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Where Did the Simufilam Data Vanish? The Filamin A Mystery

Where Did the Simufilam Data Vanish? The Filamin A Mystery

Hope for months of life was funded with sixteen million dollars in federal grants-yet investigators later found zero original data to support the mechanism behind simufilam. How did a drug program that enrolled hundreds, sparked four simultaneous investigations, and ended with the announcement “the drug did not work” come to rest on no surviving primary records?

In this episode, we tell the story of the filamin A hypothesis and the simufilam program, tracing how a single laboratory’s data became the foundation for clinical trials and…

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