Mark Cuban: Disrupting the business of healthcare, part 1

20-Minute Health Talk · May 13, 2026 · 17m

In the first episode of this two-part discussion, host Chethan Sathya, MD, sits down with entrepreneur Mark Cuban for a candid look at why Cuban has set his sights on fixing the economics of healthcare. Cuban shares how the “power of broke” shaped his risk mindset, why curiosity beats bravado, and how democratized knowledge and AI are lowering the barrier to entrepreneurship. He unpacks the origin and mission of his new pharmacy business, Cost Plus Drugs, which is all about radical price transparency, straightforward markups, and passing savings to patients. He also discusses his new pushes…