790-Whole-Body Cellular Mapping of Laboratory Mouse

Paper Talk · Apr 13, 2026 · 19m

This research introduces a pioneering spatiotranscriptomics platform designed to map the entire molecular and cellular landscape of the laboratory mouse. By combining Array-seq technology with a novel computational algorithm called LABEL, researchers can now simultaneously identify 379 distinct cell types and 16 major organ systems within a single whole-body section. This framework transitions biological study from isolated tissue analysis to a comprehensive systems biology approach, capturing how cells interact across the entire organism. To demonstrate its utility, the authors mapped…