Micro 75: Trematodes

Clinical Deep Dives · Mar 4, 2026 · 33m

This episode examines trematodes, or flukes - leaf-shaped flatworms characterised by complex life cycles involving freshwater snails. Drawing from Murray’s Chapter 75, it explores transmission dynamics, tissue localisation, and chronic disease.

Trematodes are hermaphroditic (with the exception of Schistosoma species) and require intermediate hosts. Human infection typically occurs via:

* Skin penetration by cercariae (Schistosoma)

* Ingestion of contaminated water plants or undercooked fish

Major disease categories include:

* Schistosomiasis - blood flukes causing granulomatous inflammation…