CAD: Dual vs Triple Therapy

Evidence at the Bedside · Mar 8, 2026 · 23m

In this episode of Evidence at the Bedside, we review the evidence-based management of coronary artery disease (CAD) patients requiring both anticoagulation and antiplatelet therapy. We break down practical strategies for balancing ischemic risk and bleeding risk, including guidance on dual vs triple therapy, duration of therapy, and medication selection.This discussion covers high-yield clinical scenarios such as atrial fibrillation with recent PCI, acute coronary syndrome (ACS), and patients requiring long-term anticoagulation after stent placement. We also review guideline-supported…