How McKesson Mastered Pharmaceutical Distribution

The Operations Podcast with Fexingo: Process, People, and Profit in Modern Business · May 22, 2026 · 9m · transcript

In this episode, Lucas and Luna dive into the operational genius behind McKesson—one of the world's largest pharmaceutical distributors. They explore how the company's massive DC in Olive Branch, Mississippi, processes over 100,000 unique SKUs daily with 99.9% accuracy. From the 'tote-and-chute' system to the real-time inventory algorithms that prevent drug shortages, Lucas breaks down the engineering of a supply chain most of us never see. They discuss the thin margins—around 1.5%—and how scale and precision make the business profitable. Luna asks about the bottlenecks in…