Latest / Health and Homestead Pod / Ep.8: GLP-1/GIP in Diabetes and Obesity

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Ep.8: GLP-1/GIP in Diabetes and Obesity · Health and Homestead Pod

• 0:08
  SPEAKER_01: Welcome to Health and Homestead with Laura and Alley.
• 0:13
  SPEAKER_03: Disclaimer.
• 0:14
  SPEAKER_03: This podcast is for educational and entertainment purposes only.
• 0:18
  SPEAKER_03: The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment.
• 0:24
  SPEAKER_03: Do not avoid or delay obtaining medical advice based on the shit that we say.
• 0:28
  SPEAKER_03: Thanks.
• 0:29
  SPEAKER_03: Hi.
• 0:30
  SPEAKER_03: Oh my god, welcome to episode eight.
• 0:32
  SPEAKER_03: Episode Episode.
• 0:34
  SPEAKER_03: Episode eight.
• 0:36
  SPEAKER_03: And we're already gonna break the protocol of what our podcast is because we have a heavily requested topic: obesity and GLP1 medications.
• 0:45
  SPEAKER_03: Yeah.
• 0:46
  SPEAKER_01: GLP1, GIPs, and they are indicated for both diabetes and obesity.
• 0:50
  SPEAKER_01: So hits on both of our professional snaps for both of us.
• 0:54
  SPEAKER_01: Snaps for both.
• 0:55
  SPEAKER_03: So we're gonna miss a homesteading tip today, so sorry about that.
• 0:58
  SPEAKER_01: Apologies, yeah.
• 0:59
  SPEAKER_01: Yeah, but if you cure your diabetes, it'll help you with homesteading.
• 1:02
  SPEAKER_01: I don't know.
• 1:04
  SPEAKER_00: I don't know.
• 1:05
  SPEAKER_01: It'll help you with everything.
• 1:06
  SPEAKER_03: Anyway, yeah, anyways, but yeah, we're gonna get into that today.
• 1:10
  SPEAKER_03: It's gonna be an information-packed episode.
• 1:13
  SPEAKER_01: Action-packed, but that's a good thing though, because this is everybody's own GLP1.
• 1:17
  SPEAKER_03: Yeah, it's funny because we were getting ready to press record the other day to record episode seven.
• 1:22
  SPEAKER_03: Yes.
• 1:23
  SPEAKER_03: And I had an an old customer of mine call and be like, Can I just want to know how do I get a GLP one?
• 1:28
  SPEAKER_03: Like, how do I bring it up with my doctor?
• 1:30
  SPEAKER_03: It's like, just fucking ask for it, man.
• 1:32
  SPEAKER_03: But yeah, yeah.
• 1:32
  SPEAKER_03: Anyway, it's it's heavily requested.
• 1:34
  SPEAKER_03: I get a ton of questions about it.
• 1:36
  SPEAKER_03: So we're gonna I talk about it all the time at work as a diabetes educator, so yeah.
• 1:41
  SPEAKER_03: But first, let's go over how old we are.
• 1:44
  SPEAKER_03: Okay, let's talk about this.
• 1:45
  SPEAKER_03: Yesterday I was sitting outside of my daughter's school picking her up.
• 1:50
  SPEAKER_03: She's after basketball practice.
• 1:52
  SPEAKER_03: She's in grade eight, so she is gonna be 13 next week, actually.
• 1:56
  SPEAKER_03: Oh yeah.
• 1:58
  SPEAKER_03: She was texting me on her own mobile device that she has at 12 years old and tell because we asked her what's going on this weekend, and I don't know.
• 2:06
  SPEAKER_03: Like, we'll I'll talk to my friends over the weekend and we'll make plans.
• 2:09
  SPEAKER_03: I'm like, Can you imagine how the times have changed?
• 2:12
  SPEAKER_03: Because when we were in grade eight, we had the plans set to the minute.
• 2:16
  SPEAKER_03: We did not have cell phones, we'll start there.
• 2:19
  SPEAKER_03: Yeah, they hadn't been invented yet.
• 2:20
  SPEAKER_03: They hadn't been invented yet.
• 2:22
  SPEAKER_03: But we by the time we left school at three o'clock on a Friday, like we knew what we were doing to the minute.
• 2:28
  SPEAKER_03: And why?
• 2:28
  SPEAKER_03: Why was that?
• 2:30
  SPEAKER_03: This is the process of making a plan in the 90s.
• 2:33
  SPEAKER_03: And I ran through in my head and I was like, oh my god, this is wild how different 30 years has changed things.
• 2:39
  SPEAKER_03: But so if you just left it up on a whim and wanted to make plans over the weekend, this is the process of a grade eight.
• 2:46
  SPEAKER_03: Of a grade eight, so you'd go to your landline in your kitchen on the weekend.
• 2:52
  SPEAKER_01: That's a phone with a cord for all you all you little ones out there.
• 2:56
  SPEAKER_03: The Vista, the Vista 1000 with the speed dials in the side.
• 3:01
  SPEAKER_03: Remember program the oh program the speed dials.
• 3:04
  SPEAKER_03: That was a big thing.
• 3:05
  SPEAKER_03: Yeah, no caller ID back then either, so we had no idea who was calling.
• 3:08
  SPEAKER_03: It was called now.
• 3:09
  SPEAKER_03: We just ignore if we hear a home phone, it's like, what the fuck, what the fuck kind of noise is that?
• 3:14
  SPEAKER_01: You have a home phone?
• 3:15
  SPEAKER_03: No, not anymore, but I did.
• 3:16
  SPEAKER_03: I did in my last house because I felt like I needed one, but the only people that called were people that wanted money.
• 3:22
  SPEAKER_03: Yeah, they're only telemarketers for sure.
• 3:24
  unknown: Yeah.
• 3:24
  SPEAKER_03: Anyway, so to make a phone call in the 90s, you had to first make sure no one was on the interweb.
• 3:29
  SPEAKER_03: Yeah, couldn't do both of those things at the same time.
• 3:31
  SPEAKER_03: If you had the internet, you had to shut it off because dial up internet took your phone line, children.
• 3:36
  SPEAKER_03: You would call your friend on their home phone.
• 3:41
  SPEAKER_03: Just chaos.
• 3:42
  SPEAKER_03: Yeah, absolutely.
• 3:43
  SPEAKER_03: I still have my friend's home phone numbers programmed in my own mind.
• 3:46
  SPEAKER_03: Every one of them.
• 3:47
  SPEAKER_03: But you go to the kitchen on your landline.
• 3:49
  SPEAKER_03: So we have remember we had a phone bench, like a little bench and sit on beside the phone.
• 3:53
  SPEAKER_03: Yeah.
• 3:53
  SPEAKER_03: Yeah, because that's where we had to be.
• 3:55
  SPEAKER_03: Designated phone.
• 3:56
  SPEAKER_02: We never had cordless phones back then.
• 3:57
  SPEAKER_02: No, they weren't invented yet.
• 3:59
  SPEAKER_01: You would call your friend.
• 4:00
  SPEAKER_01: You'd probably talk to their mom or dad first.
• 4:03
  SPEAKER_01: You would call their house, is what you'd do.
• 4:04
  SPEAKER_01: You wouldn't call them.
• 4:05
  SPEAKER_00: And be like, hi, is Beth home?
• 4:09
  SPEAKER_01: Oh my God.
• 4:10
  SPEAKER_01: So this is this is where my anxiety started because Wild.
• 4:13
  SPEAKER_01: I would have to write it out what I was gonna say because if the dad answered, I'd be I'd be like this, but then if the mom answered, I'd be like this, and that's where it started.
• 4:22
  SPEAKER_01: Oh my god, I'm just realizing I'll have to talk to my therapist.
• 4:25
  SPEAKER_03: Can you imagine if kids these days had to like call and talk to the gatekeeper parents before they talk to the kids?
• 4:31
  SPEAKER_01: And then you have the dads that just buck with you.
• 4:33
  SPEAKER_01: Yeah.
• 4:33
  SPEAKER_01: And then you had the dads that are like, so and just ask you.
• 4:36
  SPEAKER_01: Kings of the dad jokes.
• 4:37
  SPEAKER_01: Oh my god.
• 4:38
  SPEAKER_01: Yep.
• 4:38
  unknown: Anyway.
• 4:39
  SPEAKER_03: How's your family?
• 4:40
  SPEAKER_03: I just want to talk to Beth.
• 4:41
  SPEAKER_03: Yeah.
• 4:42
  SPEAKER_03: I just want to make plans.
• 4:43
  SPEAKER_01: I just want to are you coming over tonight to play Dream Phone or So am I taking Dream Phone to you or so?
• 4:49
  SPEAKER_03: Yeah.
• 4:49
  SPEAKER_03: We'd call them on the landline.
• 4:51
  SPEAKER_03: They'd come in their kitchen, sit in front of their whole family and talk to us on the phone.
• 4:54
  SPEAKER_03: Yeah.
• 4:54
  SPEAKER_03: We'd make a plan.
• 4:56
  SPEAKER_03: That was already made.
• 4:57
  SPEAKER_03: That was already made.
• 4:58
  SPEAKER_03: And you'd be like, all right, I'm leaving in 10 minutes.
• 5:00
  SPEAKER_03: And you just trusted that.
• 5:01
  SPEAKER_03: You couldn't track their location.
• 5:02
  SPEAKER_01: No, you couldn't text them and be like, where yet?
• 5:04
  SPEAKER_03: Yeah.
• 5:04
  SPEAKER_03: And you can sit to see where all of her friends are.
• 5:07
  SPEAKER_03: And I made her turn her location off because that's really creepy to me.
• 5:09
  SPEAKER_03: Creepy.
• 5:09
  SPEAKER_03: I don't like that at all.
• 5:10
  SPEAKER_03: But where all of her friends are in the world.
• 5:11
  SPEAKER_03: She goes, Oh, look, so-and-so is in Toronto.
• 5:14
  SPEAKER_03: I'm like, there's no reason you didn't know that.
• 5:16
  SPEAKER_03: There's no reason you need that information.
• 5:17
  SPEAKER_03: Anyway.
• 5:18
  SPEAKER_03: Wild.
• 5:19
  SPEAKER_03: So give us some more examples of the 90s and how things, how times are different because how the turns have tabled.
• 5:25
  SPEAKER_03: Yeah.
• 5:25
  SPEAKER_03: It's crazy.
• 5:26
  SPEAKER_03: Wild to me.
• 5:28
  SPEAKER_03: Anyway, that was what ran through my mind waiting for her for 45 fucking minutes yesterday after Birch.
• 5:33
  SPEAKER_03: I was wondering where you went.
• 5:34
  SPEAKER_03: She told me she was done at 4 30 because she wasn't feeling well, and then she felt fine.
• 5:39
  SPEAKER_01: And I was like, she had a text message that she could have sent you, but she didn't.
• 5:44
  SPEAKER_03: Yeah.
• 5:45
  SPEAKER_03: Oh my.
• 5:46
  SPEAKER_03: So we had a very silent drive home after I gave her the years thinking about the 90s.
• 5:52
  SPEAKER_03: Anyway.
• 5:52
  SPEAKER_03: Anyways.
• 5:53
  SPEAKER_01: Um let's get right into it.
• 5:54
  SPEAKER_01: Yep.
• 5:55
  SPEAKER_01: So I'm gonna I'm gonna start.
• 5:56
  SPEAKER_01: Um again, I'm gonna go over kind of the diabetes aspect of things.
• 5:59
  SPEAKER_01: Laura's gonna go over obesity, and this is Allie.
• 6:03
  SPEAKER_01: Nobody can tell our voices apart, even AI drive.
• 6:05
  SPEAKER_01: Speaker one, speaker two, transcribe, speaker three, speaker four question mark.
• 6:09
  SPEAKER_01: They don't know who was talking, but anyways, you guys will know.
• 6:12
  SPEAKER_01: Um, so GLP1 medication, so that's your um, like your Ozempic, your Wagovi, your rebelsis.
• 6:20
  SPEAKER_01: The Wagovi obviously is that well, not obviously, but Wagovi is the weight loss side of things, so we'll leave that one to Laura.
• 6:25
  SPEAKER_01: And there's some that you can get that are that those are just GLP1s, but you can also get a combo drug that is GLP1 and GIP.
• 6:34
  SPEAKER_01: It doesn't really matter what those mean.
• 6:36
  SPEAKER_01: You can look at you look it up.
• 6:37
  SPEAKER_03: There's long words that we don't have to go over, but you are not going to be studying for MCATs and M Clecks or whatever they're called based on this podcast.
• 6:44
  SPEAKER_01: This is if you're very general.
• 6:46
  SPEAKER_01: This is very general information.
• 6:47
  SPEAKER_01: You're gonna have to Google the rest for look in your medical textbooks.
• 6:51
  SPEAKER_01: Yeah.
• 6:51
  SPEAKER_01: Um, so the the GLP GIP combinations are like your terzeptide is the generic name for it, but Monjaro, which would be the diabetes uh form of it, and Zeppan.
• 7:01
  SPEAKER_01: Same medication, different pen.
• 7:03
  SPEAKER_01: Yes, okay.
• 7:04
  SPEAKER_01: So, what is a GLP one?
• 7:05
  SPEAKER_01: So a GLP1 is a wonderful medication.
• 7:08
  SPEAKER_01: Liquid gold is liquid gold, one would say.
• 7:11
  SPEAKER_01: Um, it's a peptide.
• 7:13
  SPEAKER_01: So it's a peptide that tells the pancreas after you eat to secrete insulin.
• 7:17
  SPEAKER_01: So insulin is something that lowers your blood sugar.
• 7:20
  SPEAKER_01: When you eat, your blood sugar goes up.
• 7:21
  SPEAKER_01: You secrete insulin normally, a normal pancreas will secrete insulin and your blood sugar will go down.
• 7:26
  SPEAKER_01: That's great.
• 7:27
  SPEAKER_01: It also helps to suppress glucagon.
• 7:29
  SPEAKER_01: Glucagon is a hormone that raises your blood sugar.
• 7:32
  SPEAKER_01: So, in suppressing that, that helps to keep your blood sugar low as well.
• 7:36
  SPEAKER_01: Um, it slows digestion and it delays gastric emptying.
• 7:39
  SPEAKER_01: That's kind of the biggest one when it comes to the side effects of this medication.
• 7:42
  SPEAKER_01: So that's we'll get into those in a minute, but that's kind of where it all stems from is that slowing, slowing down of the digestion that people aren't used to.
• 7:51
  SPEAKER_01: It also communicates with the brain, the hypothalamus, and it tells them, tell it tells them, tells all your hypothalamus that you're full.
• 7:58
  SPEAKER_01: Hypothalmi?
• 7:59
  SPEAKER_01: Hypothalmi octopod.
• 8:02
  SPEAKER_01: Tells them all that you're full.
• 8:03
  SPEAKER_01: And again, your hypothalamus is probably telling you you're full now.
• 8:09
  SPEAKER_01: If you're not on a GLP1, you're just used to ignoring it.
• 8:12
  SPEAKER_01: Um, so this is a medication that when you're on it, you should really listen to your body.
• 8:17
  SPEAKER_01: It does improve insulin sensitivity as well.
• 8:19
  SPEAKER_01: So that just means um the insulin that's in your body, sometimes it's not effective, sometimes it's there, but not doing what it's supposed to.
• 8:25
  SPEAKER_01: So GLP1s can actually make that um sensitivity, like the insulin work a little better.
• 8:31
  SPEAKER_01: Decreases food noise.
• 8:32
  SPEAKER_01: That is the biggest, one of the biggest things for people that they say that it decreases their cravings by lowering the dopamine response to food.
• 8:40
  SPEAKER_01: So you don't get it gives you pleasure.
• 8:42
  SPEAKER_01: Dopamine gives you pleasure.
• 8:43
  SPEAKER_01: So if you used to get, I mean, people are people are addicted to food.
• 8:47
  SPEAKER_01: There's that's a that's a thing.
• 8:49
  SPEAKER_01: But also if you like your treats, your sweets, your snacks, and all that stuff, um, by lowering the dopamine response, you are making it so that those foods are not not on the top of your mind.
• 9:00
  SPEAKER_01: It just makes it so decreasing food noise, that is one of the biggest um things that people say that that helps them with this medication.
• 9:08
  SPEAKER_03: Um and people that are not addicted to food or have food issues, when you say food noise, like uh the companies made that up just to sell this stuff, it was like, that's great if you've never heard food noise before.
• 9:20
  SPEAKER_03: But thanks, skinny, get out of here.
• 9:21
  SPEAKER_03: Yeah, skinny bitches can say that.
• 9:23
  SPEAKER_03: But if you've ever struggled with with weight and your relationship with food, like food noise is real, and that's a perfect way to sum it up like what it is, because it is noise, it's always there.
• 9:33
  SPEAKER_03: You're always thinking about it.
• 9:35
  SPEAKER_03: What am I gonna have for my next meal?
• 9:36
  SPEAKER_03: When am I gonna get and it truly does get rid of it?
• 9:38
  SPEAKER_03: Yeah, and it's out it's out unreal, yeah.
• 9:41
  SPEAKER_01: Crazy.
• 9:41
  SPEAKER_01: And it works directly on the brain to do that, so that's that's an important part.
• 9:45
  SPEAKER_01: So the body actually makes these things, the body makes GLP1 and the body makes GIP.
• 9:51
  SPEAKER_01: So, why do we need it in an injection?
• 9:53
  SPEAKER_01: Why do we need to take it in an exogenous kind of form?
• 9:56
  SPEAKER_01: Because the body makes it, yes, but it does destroy it minutes after it's made.
• 10:00
  SPEAKER_01: So unfortunately, if we were just relying on our own stores, they wouldn't be there for very long.
• 10:05
  SPEAKER_01: But scientists were just playing around with ghillomonsters one day.
• 10:09
  SPEAKER_01: Um scientist will do, as one will do.
• 10:13
  SPEAKER_01: They they so they took the spit, which is gross, the saliva of the gila monsters, and they found that a very, a very similar hormone lasted seven days.
• 10:22
  SPEAKER_01: So that's why you take the injection every seven days, is because this um this form lasts seven days, and it helps us to not destroy it.
• 10:29
  SPEAKER_01: So it helps to keep this, like I said, natural hormone that we normally have in our body just makes it last longer.
• 10:34
  SPEAKER_01: So that's the the purpose of the medication.
• 10:37
  SPEAKER_01: So the biggest thing is the side effects.
• 10:40
  SPEAKER_01: People come in, they know the side effects.
• 10:42
  SPEAKER_01: So they say, I don't want to go on this medication because of all of these things.
• 10:46
  SPEAKER_01: So this is why it's very important to kind of go over these and ways that you can mitigate these.
• 10:51
  SPEAKER_01: I'm not saying that you're not gonna have any of these side effects if you do these things, but we can really limit the amount that you're going to be struggling with them.
• 10:58
  SPEAKER_01: So nausea, vomiting, and diarrhea are things that can definitely happen.
• 11:04
  SPEAKER_01: But in order to kind of minimize those effects, you're going to do smaller meals because the because of the delayed gastric emptying.
• 11:11
  SPEAKER_01: If you're used to eating like a big breakfast and then you're used to eating a big lunch and a big supper, you eat your breakfast, okay.
• 11:17
  SPEAKER_01: When lunch comes around, there's still half of that food in there.
• 11:20
  SPEAKER_01: Yeah, you're used to it being digested and your belly being ready for ready for the next big meal.
• 11:25
  SPEAKER_01: That's not really what happens with this because it slows everything down.
• 11:28
  SPEAKER_01: That's how it helps with blood sugars, is because all of that food is not being digested at once, causing a sugar spike.
• 11:34
  SPEAKER_01: Um, so yeah, so they so it can cause nausea just because you're you're fuller than you want to be.
• 11:42
  SPEAKER_01: You're you're used to eating more food and now you have to cut back and you and you really I don't know.
• 11:47
  SPEAKER_03: Relate back to our constipation episode too, because your gut has it's like a brain.
• 11:51
  SPEAKER_03: It's a brain brain.
• 11:52
  SPEAKER_03: Yep.
• 11:52
  SPEAKER_03: It takes a minute for it to signal back and say you're full.
• 11:56
  SPEAKER_03: Yeah.
• 11:56
  SPEAKER_03: So if you are a really fast eater, which it's always important to eat slowly, but if you're a really fast eater and eat, neat, neat, you can't eat the same amount that you used to when you're on a GLP one.
• 12:06
  SPEAKER_03: So And once that fullness hits, you're gonna be uncomfortable, but for a super long time now.
• 12:12
  SPEAKER_03: For way longer than before because your stomach is not emptying as quickly.
• 12:16
  SPEAKER_01: So it's one thing to go to an all-you-can-eat buffet, it's another thing to go to like have a Christmas dinner or something like that.
• 12:20
  SPEAKER_01: But this is gonna be every day for you now, like if you're used to eating eating big meals.
• 12:25
  SPEAKER_01: Um, so yeah, you get fuller quicker.
• 12:27
  SPEAKER_01: So just kind of just kind of relax when it comes to that stuff.
• 12:31
  SPEAKER_01: GI upset and sulfur burps are another very common um side effect that people say.
• 12:35
  SPEAKER_01: So limiting fatty foods.
• 12:37
  SPEAKER_01: This is something that's usually part of the education, but not always.
• 12:41
  SPEAKER_01: Um, fatty foods take longer to digest.
• 12:44
  SPEAKER_01: So if they take long anyway, and then this medication is slowing down that process, they just want to get out of your body.
• 12:51
  SPEAKER_01: So they might go back up.
• 12:52
  SPEAKER_01: Instead of continuing along, they might try to go back up.
• 12:55
  SPEAKER_01: So that's where those sulfur burps kind of come from.
• 12:58
  SPEAKER_01: And of course, GI upset is just because there's it's there and and it doesn't, it doesn't want to be.
• 13:03
  SPEAKER_01: Um, acid reflux and heartburn.
• 13:05
  SPEAKER_01: So again, small meals, this is gonna help.
• 13:07
  SPEAKER_01: When it comes to acid reflux and reflux of any kind, I just think of it as your stomach's full, you're trying to put more down there, it has nowhere else to go.
• 13:15
  SPEAKER_01: Yeah, it's not gonna go down very quickly, so it's gonna come back up.
• 13:17
  SPEAKER_01: So just so that's where the vomiting comes in too.
• 13:20
  SPEAKER_01: But like reflux is just you just gotta small meals is the biggest thing.
• 13:25
  SPEAKER_01: And no eating like directly before bed.
• 13:27
  SPEAKER_01: Yes, because when you lay down, if it's still in your belly, it's gonna want to come back up.
• 13:31
  SPEAKER_01: Because the recommendation for eating anyway is like sitting up for 30 to 45 minutes after.
• 13:36
  SPEAKER_01: This slows everything down, so it's like I don't know what the actual number is, but like it would be like an hour and a half to two hours.
• 13:42
  SPEAKER_01: Like you really have to be mindful of these things.
• 13:44
  SPEAKER_01: Constipation.
• 13:45
  SPEAKER_01: Please refer to our last episode on that.
• 13:48
  SPEAKER_01: But the biggest thing, the D for D, if you if you will, was fiber, fiber, water, and movement.
• 13:54
  SPEAKER_01: If you make these kind of changes when you start taking this medication, uh, that's really gonna help.
• 14:00
  SPEAKER_01: So fiber, make sure anytime you increase your fiber, you increase your water because those two go together.
• 14:06
  SPEAKER_01: They're like a synergistic relationship, kind of.
• 14:08
  SPEAKER_01: Just like us.
• 14:09
  SPEAKER_01: So just like just like better together.
• 14:11
  SPEAKER_01: Just like our us sister.
• 14:12
  SPEAKER_01: So um, so yeah, if you think of constipation, think of us.
• 14:16
  SPEAKER_01: In other words, pretty much the other biggest thing, and a lot of people this is kind of a longer term one, but a decrease in lean muscle mass.
• 14:25
  SPEAKER_01: Yes, if you take this needle and you change absolutely nothing um about your kind of behaviors, your daily behaviors, you are decreasing your appetite.
• 14:35
  SPEAKER_01: So you are decreasing the amount of overall energy that you're taking in, but that means you're taking in less protein.
• 14:40
  SPEAKER_01: Protein is the building block to building blocks to muscles.
• 14:43
  SPEAKER_01: So if you protein's the D for D.
• 14:45
  SPEAKER_01: Protein's the D for D for fucking everything, but we just don't get enough protein, and you really think you do until you monitor it, and then you realize you don't at all.
• 14:54
  SPEAKER_01: Um, so making sure you are focusing on small, um protein-rich meals, but also like what's the word I'm looking for?
• 15:02
  SPEAKER_01: The um nutrient-dense is the word.
• 15:07
  SPEAKER_01: Yes, so nutrient-dense.
• 15:08
  SPEAKER_01: Make your food count.
• 15:09
  SPEAKER_01: Make your food count.
• 15:10
  SPEAKER_01: That's exactly what it is.
• 15:12
  SPEAKER_01: So um strength and strength training is another one.
• 15:16
  SPEAKER_01: So if you put resistance on your muscles, that is what is going to grow them, that is what's going to maintain them, and that is what's going to make it so that the things that you're doing now are going to help you in the future.
• 15:26
  SPEAKER_01: So the more you do now, as far as weight training and as far as exercise, that kind of thing, it's kind of like building your muscles for later in life when they um may not be as strong.
• 15:36
  SPEAKER_01: There's other side effects that are, so those are kind of the common ones that people bring up and that happen kind of on the day-to-day.
• 15:42
  SPEAKER_01: But there are more serious ones that are rare, of course.
• 15:45
  SPEAKER_01: Um, pancreatitis is something that can um a side effect, really not a lot of evidence for.
• 15:50
  SPEAKER_03: The evidence is like the placebo group had 14 cases, the GLP one had 17.
• 15:56
  SPEAKER_03: Like it's not a significant amount.
• 15:58
  SPEAKER_01: Yeah.
• 15:58
  SPEAKER_01: But it can happen.
• 15:59
  SPEAKER_01: But enough, enough that it is, it is listed.
• 16:01
  SPEAKER_01: Um, acute can kidney injury is another thing.
• 16:03
  SPEAKER_01: But of course, if you're nauseated and you're vomiting and you're not eating and you're have diarrhea um and you're losing all this fluid, your kidneys are gonna be affected.
• 16:11
  SPEAKER_01: So that's they're gonna be very upset as well as your GI.
• 16:15
  SPEAKER_01: So that's why that could lead to that.
• 16:18
  SPEAKER_01: And gallbladder disorders is another one.
• 16:20
  SPEAKER_01: But trying to um mitigate these side effects are really gonna help with with all those.
• 16:26
  SPEAKER_01: So that is kind of the side effects for both GLPs, GLP1s, as well as the GLP1 and GIP mixes.
• 16:34
  SPEAKER_01: Um, so they're kind of like the combo drug.
• 16:36
  SPEAKER_01: The only difference that I found for the combination drugs, which is your trazeptide, which is your Monjaro, which is the diabetes form, and the Zeppam.
• 16:45
  SPEAKER_01: That's it's the exact same medication, it's the exact same dosing schedule, actually.
• 16:49
  SPEAKER_01: It's different pen, like that's the only thing different about it.
• 16:52
  SPEAKER_01: But one one test, one was uh done the clinical trials of one was done on diabetics, and the clinical trials of the other was done on obese population.
• 16:59
  SPEAKER_01: So that's really the only difference.
• 17:01
  SPEAKER_01: But they are more effective, and we see it in practice, and we can see that these are are more effective with both weight loss and um helping with your sugars because they act directly, GIPs act directly on fat tissue and improve how the body clears and stores fat.
• 17:16
  SPEAKER_01: So that's the biggest thing.
• 17:18
  SPEAKER_01: Um, they have a more pronounced effect on lipid metabolism, and that is why it helps with it, probably helps with your insulin sensitivity as well, obviously, if you're losing fat and it's helping with insulin sensitivity.
• 17:29
  SPEAKER_01: So all of the side effects for whether it be Ozempic or Monjaro for diabetes, the side effects are are generally the same.
• 17:37
  SPEAKER_01: Unfortunately, the price is not the same.
• 17:39
  SPEAKER_01: So the GLP1 GIPs are usually more expensive.
• 17:42
  SPEAKER_01: Weight loss side of things, which Laura's going to talk about, aren't always covered by your insurance company.
• 17:46
  SPEAKER_01: So that's that's kind of the other things.
• 17:49
  SPEAKER_01: That's kind of the other things too.
• 17:50
  SPEAKER_01: But there are there are apps that you can um can download.
• 17:53
  SPEAKER_01: I downloaded one.
• 17:54
  SPEAKER_01: I was like on your injection day, make sure that before you take your injection, you have a high protein meal.
• 17:59
  SPEAKER_01: Make sure you're drinking a lot of water and then have another high protein meal after your injection.
• 18:03
  SPEAKER_01: So you really have to do your your research when it comes to this.
• 18:06
  SPEAKER_01: Like do your due diligence and just make sure if you are taking these medications that you're following these, I don't say it's a it's a big thing, but you may have to make some some behavior changes, and that's okay.
• 18:16
  SPEAKER_01: And that's that's part of it too.
• 18:18
  SPEAKER_01: But um, so yeah, so that's kind of the diabetes side of things.
• 18:21
  SPEAKER_01: But where does it fit in treatment?
• 18:23
  SPEAKER_01: So, yeah, so it's not usually a first-line, um, a first-line treatment.
• 18:27
  SPEAKER_01: We do find that because usually like your metformin's your um your glycosides, whatever would be kind of your first line, but because they're cheaper.
• 18:34
  SPEAKER_01: Because they're cheaper.
• 18:36
  SPEAKER_01: Exactly.
• 18:37
  SPEAKER_01: They do like cheaper.
• 18:38
  SPEAKER_01: Um, if you are on insulin though, even if you're not on insulin, it can reduce the need of other medications just because it's so effective, but it does decrease um insulin need.
• 18:48
  SPEAKER_01: Yeah.
• 18:48
  SPEAKER_01: For the for big part, but like I said, Monjaro, sorry, was empic, but Monjaro is more effective.
• 18:55
  SPEAKER_01: The studies have shown that.
• 18:56
  SPEAKER_01: I'm not just that's not an opinion, that's a that's a fact, but it's also a combo medication.
• 19:00
  SPEAKER_01: It's a different, essentially, it's a it's a little bit extra, and that's why is because it works more like fat.
• 19:05
  SPEAKER_01: Exactly.
• 19:06
  SPEAKER_01: Yeah, so it helps with with both.
• 19:08
  SPEAKER_01: So um, so yeah, so that's kind of the diabetes piece of things, but Laura's gonna go into obesity because it is so important, and it is now a chronic disease.
• 19:18
  SPEAKER_03: It is segue.
• 19:19
  SPEAKER_03: Awesome.
• 19:20
  SPEAKER_03: Obesity is finally, finally recognized as a chronic disease.
• 19:24
  SPEAKER_03: So diabetes, high blood pressure, high cholesterol, these are chronic diseases that basically means it lasts your whole lifetime.
• 19:31
  SPEAKER_03: Obesity is one of those.
• 19:33
  SPEAKER_03: So they finally recognize it as that.
• 19:36
  SPEAKER_03: It's driven by biology, it's not a choice, it's not calories in, calories out for a lot of people.
• 19:41
  SPEAKER_03: I think 70% of obesity population, it's a large part because of genetics, so it's not your fault.
• 19:48
  SPEAKER_03: Um listen up, boomers.
• 19:50
  SPEAKER_03: Yeah, a lot of people are like, I just I can do this on my own, and maybe, maybe, maybe, but it's it's something's gonna be with you for your life, like it's gonna be a struggle.
• 20:00
  SPEAKER_03: So there is treatment for obesity now.
• 20:04
  SPEAKER_03: Um, it impacts health early.
• 20:06
  SPEAKER_03: So new evidence has shown that children living with obesity or obesity earlier in life can cause a lot of health issues later in life.
• 20:16
  SPEAKER_03: So type 2 diabetes, hypertension, whatever.
• 20:20
  SPEAKER_03: The impacts of obesity hit early.
• 20:23
  SPEAKER_03: Um, so it's important to kind of nip it when we can.
• 20:26
  SPEAKER_03: It's treatable, like I said.
• 20:28
  SPEAKER_03: So we have these medications now, which we call them liquid gold because they're just they're great, but there's also, you know, there's surgeries, there's lifestyle interventions, there's behavioral therapies that can help with obesity.
• 20:38
  SPEAKER_03: The biggest thing I want to say, like the stigma around obesity though, has to change.
• 20:42
  SPEAKER_03: It's gotta stop, man.
• 20:43
  SPEAKER_03: It's gotta stop.
• 20:44
  SPEAKER_03: Yeah, it's limiting people asking for help, seeking uh help, seeking these medications, and it's it's harms self-esteem.
• 20:52
  SPEAKER_03: Like, there's there's no need, there's no reason in the world why you should comment on somebody's weight.
• 20:57
  SPEAKER_03: And I my my daughter, I always taught her this too.
• 21:00
  SPEAKER_03: It's like, don't don't comment on something that someone couldn't change in five seconds.
• 21:05
  SPEAKER_03: Five seconds, yeah.
• 21:05
  SPEAKER_03: So if you have something in your teeth, you can say, like, yeah, you got shit in your teeth because you can change that in five seconds.
• 21:10
  SPEAKER_03: Weight, hair, skin, like anything like that.
• 21:15
  SPEAKER_03: It's none of your goddamn business.
• 21:16
  SPEAKER_03: Like, it's none you can have thoughts, whatever.
• 21:19
  SPEAKER_03: If you're don't be a dick, is that's pretty much what we're self-esteem, especially in younger people.
• 21:27
  SPEAKER_03: But it's not their fault.
• 21:28
  SPEAKER_01: Girls and boys, it doesn't matter.
• 21:30
  SPEAKER_03: Just there's obesity, there's genetic links to it.
• 21:33
  SPEAKER_03: So a definition of diabetes or diabetes.
• 21:37
  SPEAKER_03: No, that to me.
• 21:39
  SPEAKER_03: Definition of obesity, because I do love a good definition, but it's excess or dysfunctional body fat that impairs health and increases risk of long term complications.
• 21:48
  SPEAKER_03: So that contributes, biology contributes, genetics contribute, environmental factors contribute.
• 21:54
  SPEAKER_03: Like try to eat healthy, try to afford to eat healthy these days.
• 21:57
  SPEAKER_01: Well, that's exactly it.
• 21:58
  SPEAKER_01: But try to eat healthy, but the Healthy foods that you're eating have so radically modified.
• 22:04
  SPEAKER_01: It's yeah, yeah.
• 22:06
  SPEAKER_03: So uh it's not definitely it's cheaper to eat shitty these days, which is unfortunate, but um it's not a lack of willpower.
• 22:15
  SPEAKER_03: And I just want to really drive that home.
• 22:17
  SPEAKER_03: It's not it's not your fault.
• 22:20
  SPEAKER_03: So do not hesitate.
• 22:21
  SPEAKER_03: If you're looking for help, if you're looking for advice on obesity management, please don't be afraid to ask for it.
• 22:29
  SPEAKER_03: I had actually when we we recorded our last episode, I had one of my We just we just sat down in the closet to record.
• 22:37
  SPEAKER_03: And one of my old customers called me and was like, How do I ask for it with my doctor?
• 22:41
  SPEAKER_03: I'm like, just just say it.
• 22:42
  SPEAKER_03: Yeah.
• 22:42
  SPEAKER_03: Just say it.
• 22:43
  SPEAKER_03: They're not I mean, it's a conversation I can guarantee five people have already asked that day.
• 22:49
  SPEAKER_03: Do not be afraid to ask for it.
• 22:51
  SPEAKER_01: Um And we're not gonna say that healthcare providers don't have stigma too.
• 22:56
  SPEAKER_01: Like there's exactly so I mean, if it's something that there's there's some doctors out there that will just be like, oh, have you tried blah, blah, blah, blah, blah.
• 23:04
  SPEAKER_03: But and that's fair because it's every these medications are always in addition to healthy diet exercise.
• 23:11
  SPEAKER_03: Like it's not, this isn't a miracle that's gonna work all on its own.
• 23:14
  SPEAKER_03: It probably will help you lose a little bit of weight, but the healthy changes that you're wanting from these medications take work.
• 23:21
  SPEAKER_03: Yep.
• 23:22
  SPEAKER_03: Yeah.
• 23:22
  SPEAKER_03: Um, so yeah, chronic diseases last a lifetime, like diabetes.
• 23:26
  SPEAKER_03: Just treat it, treat obesity like diabetes.
• 23:30
  SPEAKER_03: BMI.
• 23:31
  SPEAKER_03: How we measure obesity is through body mass index or BMI.
• 23:35
  SPEAKER_01: Stupidest fucking metric of all time.
• 23:37
  SPEAKER_01: It is.
• 23:38
  SPEAKER_03: And but it's all we have.
• 23:39
  SPEAKER_03: It's they're working for working on it.
• 23:42
  SPEAKER_03: So when you look at the indications and like who can get these things prescribed, it's not just BMI anymore, it's like waist circumference because holding weight in your middle can be a lot more dangerous than holding weight.
• 23:53
  SPEAKER_03: Like perimenopause.
• 23:55
  SPEAKER_01: Like perimenopausal one.
• 23:56
  SPEAKER_03: Oh my god, we're just connecting all over the place.
• 23:58
  SPEAKER_03: Yeah.
• 23:59
  SPEAKER_03: Uh but body composition.
• 24:00
  SPEAKER_03: So if you're like if you are heavy into weightlifting, your weight and your height could actually say that you're obese.
• 24:07
  SPEAKER_03: But you're like 10% body fat and you're like, yeah, it's it's stupid.
• 24:11
  SPEAKER_01: But body composition, they need something to measure, they need a metric, and that's what we have, but it's changing, yeah, which is good.
• 24:18
  SPEAKER_03: Yep.
• 24:18
  SPEAKER_03: And overall health status.
• 24:19
  SPEAKER_03: So how healthy you are on paper.
• 24:22
  SPEAKER_03: On paper, like how's your blood pressure, how's your cholesterol?
• 24:25
  SPEAKER_03: Because you can be obese and be completely healthy on paper.
• 24:28
  SPEAKER_03: You know, it's whatever.
• 24:30
  SPEAKER_03: But there's all kinds of different measurements that they're starting to use now.
• 24:32
  SPEAKER_03: It's not just real related to BMI.
• 24:35
  SPEAKER_03: Um, the treatment for obesity.
• 24:38
  SPEAKER_03: So there's a lot of treatments available.
• 24:40
  SPEAKER_03: So behavioral interventions, behavioral therapies, those are great.
• 24:46
  SPEAKER_03: They're like a kind of a standard of care.
• 24:48
  SPEAKER_03: Exercise, calorie-reduced diet.
• 24:51
  SPEAKER_03: These treatments, strength training.
• 24:53
  SPEAKER_03: Yeah.
• 24:54
  SPEAKER_03: The injections, the pills, all these medications is always in addition to a calorie-reduced diet and exercise.
• 25:01
  SPEAKER_03: But I will say if you started GLP1, the calorie reduction is not going to be a problem.
• 25:06
  SPEAKER_03: It's just gonna be, like Allie said, making nutrient-dense choices and making your food count because protein is super important.
• 25:16
  SPEAKER_03: But in Canada, as of today, October 2026, the indications for using Wigovi.
• 25:24
  SPEAKER_03: I'm gonna say Wigovi because I think the the MASH one is just Wigovi, but yeah, and Zepp bound.
• 25:29
  SPEAKER_03: I don't think it's obvious.
• 25:30
  SPEAKER_03: BMI over 30, which honestly does not take much.
• 25:34
  SPEAKER_03: But over 30, you're classified as obese, you can get these medications prescribed.
• 25:39
  SPEAKER_03: Uh number two, a BMI over 27, so overweight, and then with one weight-related comorbidity.
• 25:46
  SPEAKER_03: So if you have type 2 diabetes, hypertension, high cholesterol, obstructive sleep apnea, and your BMI is over 27, you can get these things prescribed.
• 25:53
  SPEAKER_03: It's indicated for you.
• 25:55
  SPEAKER_03: If you have a BMI over 27 and have established cardiovascular disease, so if you've had a stroke, a heart attack, or if you're diagnosed peripheral artery disease, you they're indicated to reduce the risk of major events.
• 26:09
  SPEAKER_03: So to slow the progression.
• 26:11
  SPEAKER_03: Because if you have a heart attack, you're more at risk of a heart attack.
• 26:13
  SPEAKER_03: We're in we're kind of in secondary prevention mode then.
• 26:16
  SPEAKER_03: This can decrease your risk.
• 26:18
  SPEAKER_01: Secondary prevention is still prevention, though.
• 26:19
  SPEAKER_01: So very important.
• 26:21
  SPEAKER_03: Yeah.
• 26:22
  SPEAKER_03: Uh pediatric patients.
• 26:23
  SPEAKER_03: So Wagovi is now indicated for 12 to 18 years.
• 26:28
  SPEAKER_03: If they're in the 95th percentile of weight for their age and sex, and there's a chart that you go by.
• 26:34
  SPEAKER_03: But also if their weight's over 132 pounds, which is a weird measurement, but it goes by kilos, 132.
• 26:40
  SPEAKER_03: Ah, 131, damn it.
• 26:41
  SPEAKER_03: Damn it.
• 26:42
  SPEAKER_03: And an inadequate response to diet and exercise.
• 26:45
  SPEAKER_03: So this goes back to making sure obesity is treated early in life because the outcomes are worse for people that are obese earlier in life.
• 26:54
  SPEAKER_03: And number five, it's actually indicated now for treatment of non-cerrhotic liver fibrosis.
• 27:00
  SPEAKER_03: So MASH, there's a it's an acronym.
• 27:03
  SPEAKER_03: I'm not going to go over it, but if you have a certain type of liver disease, it can help um treat that.
• 27:09
  SPEAKER_03: So there's five different reasons.
• 27:12
  SPEAKER_03: And this is kind of the meat and potatoes because I get so many questions about like number one, how do I get it prescribed?
• 27:18
  SPEAKER_03: So you have to meet one of those criteria for a doctor to prescribe it for you or a nurse practitioner.
• 27:22
  SPEAKER_03: Number two, how do I get it covered?
• 27:24
  SPEAKER_03: That's the biggest thing.
• 27:27
  SPEAKER_03: No.
• 27:28
  unknown: No.
• 27:29
  SPEAKER_03: A lot of drug plans are starting to pick it up as now that it's a chronic disease, recognized as a chronic disease, but also because it decreases the risks of all these other health conditions, drug plans are a little bit more willing to pick up the cost of it.
• 27:45
  SPEAKER_03: But my biggest as a pharmacist, my best advice I can give you is if you have a private drug plan, like Blue Cross, um, Sun Life, what do you do, ESI, like all commerce, whatever.
• 28:03
  SPEAKER_03: The you call your drug plan and ask them straight out if we go V or is that bound or covered.
• 28:09
  SPEAKER_03: If it is, they'll give you like a no or they'll give you a yes, but you need to fill out this paperwork.
• 28:15
  SPEAKER_03: Ask them to send the paperwork directly to your email because a lot of them will say, go online and find the form.
• 28:22
  SPEAKER_03: I know with Blue Cross personally, Blue Cross has different forms for diabetes, for weight loss, for if you have liver disease, if you've had a heart attack.
• 28:30
  SPEAKER_03: Like there's there's all kinds of different forms.
• 28:32
  SPEAKER_03: So get them to send the one that you need to make sure that that's not a holdup for coverage for you, and then take it to your practitioner to fill out.
• 28:39
  SPEAKER_01: And then you can also follow up with them in a couple weeks or whatever just to make sure they gut yet form.
• 28:46
  SPEAKER_01: Yeah.
• 28:46
  SPEAKER_01: I've had that happen where it's been, it it took months and months and months.
• 28:50
  SPEAKER_01: Yeah.
• 28:51
  SPEAKER_01: I've I've had that happen at work too.
• 28:53
  SPEAKER_03: A doctor, a nurse practitioner, and most of the time a pharmacist can fill out these forms for you.
• 28:58
  SPEAKER_03: So if you can't get back into your doctor, if you get them prescribed and you're like, great, that's great, but they're not covered, check with your pharmacist because they may be able to fill out the forms for you, but your drug plan will tell you if they're able to do it for you.
• 29:13
  SPEAKER_03: I'm gonna say, be prepared.
• 29:15
  SPEAKER_03: If you have pharmacare, in Nova Scotia, we have pharmacare for seniors for low-income, uh, farm family pharmacare, seniors pharmacare does not cover weight management yet.
• 29:25
  SPEAKER_03: Hopefully, yep.
• 29:26
  SPEAKER_03: Yep.
• 29:26
  SPEAKER_03: Yep.
• 29:27
  SPEAKER_03: It covers them for diabetes and for heart disease if you meet certain questions for the city.
• 29:31
  SPEAKER_03: With exemption status, yeah.
• 29:32
  SPEAKER_03: Yeah.
• 29:32
  SPEAKER_03: But if you are using them for obesity, it is not covered.
• 29:36
  SPEAKER_03: So the different kinds of treatments available, like the GLP one, so we have Wigovi is for obesity.
• 29:44
  SPEAKER_03: We have Ozempic, which is for diabetes, but used for obesity as well.
• 29:50
  SPEAKER_03: And we have ribelsis, which is a pill.
• 29:52
  SPEAKER_03: So some people are dead against using a needle, and that's okay.
• 29:55
  SPEAKER_03: Whatever.
• 29:55
  SPEAKER_03: It's once a week, it's very easy.
• 29:57
  SPEAKER_03: Like once you do it once, you'll be like, oh, okay.
• 29:59
  SPEAKER_03: But if you're if you have a needophobia, that's okay.
• 30:01
  SPEAKER_03: Like there's there's other medications.
• 30:04
  SPEAKER_03: Um you take the the needle ones you take once a week.
• 30:10
  SPEAKER_03: Ribelsis, you take every day as a pill.
• 30:13
  SPEAKER_01: On an empty stomach, half hour before your first meal.
• 30:16
  SPEAKER_03: Very specific time.
• 30:17
  SPEAKER_03: But you can, it's it's an option to do it.
• 30:20
  SPEAKER_03: You also have the GLP GIP combos, which is the ZEP bound for obesity, the Mongero for diabetes.
• 30:28
  SPEAKER_03: There's also other medications that are not GLP1 medications for obesity.
• 30:33
  SPEAKER_03: So Contrave is the one that comes to mind most.
• 30:36
  SPEAKER_03: It's it's uh it's a pill.
• 30:38
  SPEAKER_03: The dose that you have to get up to is two tablets in the morning, two tablets in the evening.
• 30:41
  SPEAKER_03: So it is four pills a day.
• 30:43
  SPEAKER_03: Um but it's a combination of an antidepressant and an opioid antagonist, actually.
• 30:49
  SPEAKER_03: So it does work on the hypothalamus, similar to GLP1.
• 30:52
  SPEAKER_03: It controls your hunger pathways, your cravings, and decreases your food pleasure.
• 30:58
  SPEAKER_03: But there are some it there's some reasons you can't take that.
• 31:02
  SPEAKER_03: So if you have a seizure disorder, the antidepressant in that one is well butrin.
• 31:07
  SPEAKER_03: The contraindication to well butrin is seizure disorder because it can lower your seizure threshold.
• 31:11
  SPEAKER_03: So you cannot take that if you have seizure disorder.
• 31:14
  SPEAKER_03: If you have uncontrolled hypertension, so you have to get your blood pressure under control first.
• 31:18
  SPEAKER_03: A lot of people take opioids for chronic pain.
• 31:21
  SPEAKER_03: So if you're taking Tylenol 3 or codeine or whatever daily for like pain management, contrave is not for you because the opioid antagonist will cause you to go into withdrawal of opioids, it'll completely negate the pain effect of your opioid.
• 31:36
  SPEAKER_03: But that's that's for the contrave specifically for GLP1 GIP combinations.
• 31:43
  SPEAKER_03: Allie went over the side effects already, but the the contraindication, so you cannot take these if you are pregnant or breastfeeding.
• 31:50
  SPEAKER_03: And the reason being because they're not studied, it's not ethical to test things in pregnant ladies, so or pregnant mice, apparently.
• 31:58
  SPEAKER_03: Maybe, maybe it's okay, but we can't you can't because it's not studied in pregnant.
• 32:02
  SPEAKER_03: Um, if you have gastroparesis, so a paralysis of your like gastric emptying, that's a condition that it's not a common condition, but you can't take it if you have that.
• 32:13
  SPEAKER_03: If you have a history of pancreatitis, or if you have personal or family history of medullary thyroid cancer, multiple endocrine neoplasia, so M-E-N 2A or 2B or this certain type of thyroid cancer, because the rodent studies have shown that it can increase the risk of those little tiny hairy people.
• 32:31
  SPEAKER_03: Yep.
• 32:32
  SPEAKER_03: Not that I don't think there's any studies in humans, but with the most of the studies are done in rodents first, and that they have shown some increase in the world.
• 32:40
  SPEAKER_03: We are the study.
• 32:41
  SPEAKER_03: We are the study.
• 32:42
  SPEAKER_03: Absolutely.
• 32:43
  SPEAKER_03: Um, but those when when you can't take them, coverage for them is iffy, every plan is different, you have to call them and it changes all the time.
• 32:53
  SPEAKER_03: I know when I started, I'm on a JLP one.
• 32:56
  SPEAKER_03: I've been on one for seven years or almost, I don't know.
• 33:00
  SPEAKER_03: When saxending saxend is not even sold anymore.
• 33:02
  SPEAKER_03: That's what I started on.
• 33:04
  SPEAKER_03: Um, it was a lot easier to get them covered back then, I'm gonna say, because now everybody wants them because they've been shown to work so well.
• 33:13
  SPEAKER_03: And just because you meet the criteria to get them prescribed does not mean your drug plan will cover them.
• 33:19
  SPEAKER_03: So I know like obesity is 30 BMI or over.
• 33:23
  SPEAKER_03: There's certain plans now that only cover them for BMI over 35.
• 33:27
  SPEAKER_03: Yeah.
• 33:27
  SPEAKER_03: Or BMI over 30 plus these weight conditions.
• 33:30
  SPEAKER_03: So the indications for use, like who can get them and who can get them covered, do not correlate.
• 33:36
  SPEAKER_03: I think drug plans kind of go, they try to not get them covered.
• 33:40
  SPEAKER_03: But if you are willing, Ozempic now is generic.
• 33:43
  SPEAKER_03: So Wigovi's not generic yet.
• 33:46
  SPEAKER_03: Mongero's that bound, they have a patent for another couple years, so they won't be generic anytime soon.
• 33:50
  SPEAKER_03: But Ozempic, you can get a generic form of Ozempic.
• 33:54
  SPEAKER_03: It's about$90 a month to get prescribed Ozempic and take it.
• 33:58
  SPEAKER_03: If you're willing to pay that out of pocket, go into your doctor and say, it's it's there.
• 34:02
  SPEAKER_03: Let's try the coverage piece, but I'm willing to pay for it.
• 34:05
  SPEAKER_03: That's a lot of dollars though.
• 34:06
  SPEAKER_03: Yep.
• 34:07
  SPEAKER_03: Um in today's economy?
• 34:08
  SPEAKER_03: Yeah.
• 34:09
  SPEAKER_03: But that's for Ozempic cymagliotide generic only.
• 34:13
  SPEAKER_03: WeGovi is about, well, it's about$450 a month as of October 2026.
• 34:20
  SPEAKER_03: You can, every drug has its a plan though.
• 34:23
  SPEAKER_03: Like they all have patient support programs.
• 34:25
  SPEAKER_03: So Ozempic Care, Wagovi Care, and then like My Mongero, MyZBound.
• 34:31
  SPEAKER_03: If you go on the websites of these plans, they will usually give you these cards you can take to the pharmacy to reduce the price.
• 34:36
  SPEAKER_03: But it's with Wagovi, for example, it reduces the price from 400 and some to 300 and some.
• 34:42
  SPEAKER_01: But it can get rid of your copay, though.
• 34:44
  unknown: Yeah.
• 34:44
  SPEAKER_01: If you if you have a copay on your on your prescriptions, then it can help with that.
• 34:48
  SPEAKER_03: Yeah.
• 34:48
  SPEAKER_03: And if you're a cash-paying customer, so if you have pharmacare and you don't you don't have no coverage for these things, getting one of those cards can take the price down for you.
• 34:59
  SPEAKER_03: But it's still a lot of money.
• 35:00
  SPEAKER_03: It's still a lot of money.
• 35:01
  SPEAKER_01: Especially when you probably have other medications you have to pay for too.
• 35:05
  SPEAKER_01: Like it's it usually, yeah.
• 35:06
  SPEAKER_03: Yeah.
• 35:07
  SPEAKER_03: A lot of the time though, it can decrease the need for other medications.
• 35:10
  SPEAKER_03: Yeah.
• 35:11
  SPEAKER_03: Or reduce doses like insulin, things like that.
• 35:14
  SPEAKER_03: But check with your plan.
• 35:16
  SPEAKER_03: I guess that's the biggest advice I can say as a pharmacist is like you get the prescription, that's great, go to the pharmacy.
• 35:21
  SPEAKER_03: It's not covered.
• 35:21
  SPEAKER_03: It's like, okay, what do I do now?
• 35:23
  SPEAKER_03: You can be ahead of that by calling your plan ahead of time and saying, like, I'm going to the doctor, I want to get Govey, what do I do?
• 35:30
  SPEAKER_03: You take the forms with you to the appointment and kind of work on the coverage piece there.
• 35:36
  SPEAKER_01: But or call the company.
• 35:38
  SPEAKER_01: The company wants your money.
• 35:40
  SPEAKER_01: They do, and the the brand name companies.
• 35:42
  SPEAKER_01: The brand name companies want your money.
• 35:43
  SPEAKER_01: Generic, I mean, whatever, but they want your money.
• 35:46
  SPEAKER_01: So if you call them and say it's a it's a difference of me taking this medication and you getting some of my money, or me not taking it all and you getting none of my money, they may do something to help you out.
• 35:54
  SPEAKER_01: So it's no shame, man.
• 35:56
  SPEAKER_01: No shame.
• 35:56
  SPEAKER_01: Call the company and see what they can do for you.
• 35:58
  SPEAKER_01: Yeah.
• 35:59
  SPEAKER_03: And there's issues with shortages.
• 36:00
  SPEAKER_03: I know with when Ozempic was generic, when Symaglitide Generic came out, there were so many people that were like, oh, it's short.
• 36:06
  SPEAKER_03: I can't, I can't get it, which means it's not available.
• 36:09
  SPEAKER_03: So we have to switch it back to brand name Ozempic.
• 36:12
  SPEAKER_03: The companies want you to use brand name too, so they will give you something to make you take brand name for the cost of the generic.
• 36:19
  unknown: Exactly.
• 36:20
  SPEAKER_01: Once the generic comes out because they are losing money.
• 36:22
  SPEAKER_01: That's why.
• 36:23
  SPEAKER_03: Just do your do your due diligence, call your drug plans.
• 36:26
  SPEAKER_03: Um, a lot of the times drug plans won't talk to health professionals, and that's why I ask you to do this ahead of time because you get to the pharmacy, it's not covered, we call them, we're like, nope, I can only talk to the card holder.
• 36:35
  SPEAKER_03: So do that first.
• 36:37
  SPEAKER_03: That's very helpful for us.
• 36:38
  SPEAKER_03: And then you know right off the bat, if you if you know you can pay$90 a month if it's not covered, bonus if it is covered.
• 36:46
  SPEAKER_03: But if it's not, then it's just something you're gonna have to be willing to pay.
• 36:49
  SPEAKER_03: So um those that's that's the main questions I get.
• 36:54
  SPEAKER_03: Yeah, yeah.
• 36:55
  SPEAKER_01: And that's the nitty, that's the nitty and the gritty but the biggest thing is like with the side effects, because that's everybody's obviously that's why they don't want to take meds because of the side effects.
• 37:04
  SPEAKER_01: But if you know what the side effects are and you know how to help reduce them, it can really make your quality of life better during this.
• 37:12
  SPEAKER_03: Personal experience too.
• 37:13
  SPEAKER_03: I find like the first two days after injection day, so I inject on Friday because in my mind I know I can't eat shitty on the weekends.
• 37:22
  SPEAKER_03: That helps me.
• 37:23
  SPEAKER_03: So I know that on Saturday and Sunday I have to be careful what I eat because I find the nausea may be a little bit worse those first couple days, especially fatty food.
• 37:31
  SPEAKER_03: Yeah, especially if you eat shitty.
• 37:32
  SPEAKER_03: So it's a little mind game I play with myself.
• 37:35
  SPEAKER_03: Well, I mean if it works, it works.
• 37:37
  SPEAKER_03: Yeah, and if you know your weekend is like uh every night I have every Friday night I get pizza.
• 37:43
  SPEAKER_03: Maybe your injection day should be like Tuesday.
• 37:45
  SPEAKER_01: Yeah, yeah.
• 37:46
  SPEAKER_01: You don't want to power through with yeah, and there's nothing wrong with having pizza, and that's another thing too, like with the with the stigma.
• 37:52
  SPEAKER_01: Yeah, like it's just I don't know, don't comment on people's food.
• 37:56
  SPEAKER_01: I don't eat salads, you don't make friends with salads.
• 37:58
  SPEAKER_03: No, I just eat less of what I usually eat, and I really focus on protein.
• 38:02
  SPEAKER_03: So there I actually posted a video on Facebook and our YouTube, like our Health and Homestead one, just of a 50 gram protein shake, because that's what I usually use every morning.
• 38:11
  SPEAKER_03: You use high protein milk, you use like the good protein, high protein stuff.
• 38:15
  SPEAKER_03: It's 50 grams of protein in a shake.
• 38:18
  SPEAKER_03: And my goal every day is usually like 100 to 125 grams of protein.
• 38:23
  SPEAKER_03: That's a fucking lot.
• 38:24
  SPEAKER_01: Yeah, well, mine's more because it's per kilogram or whatever.
• 38:27
  SPEAKER_01: Yeah.
• 38:28
  SPEAKER_01: But it's difficult and it's expensive.
• 38:30
  SPEAKER_01: Like it's just one of those things.
• 38:32
  SPEAKER_01: So when you're if you're paying for food, pay for good quality food because I mean, if you're eating chips and stuff, it's just not you're not getting the calories, you're not getting the protein you need.
• 38:41
  SPEAKER_03: So and relate back to our previous conversations.
• 38:44
  SPEAKER_03: If you buy vegetables, you don't eat them all, make them into powders, man.
• 38:48
  SPEAKER_03: Powder it up, save food waste.
• 38:50
  SPEAKER_03: Don't don't waste any, it's too expensive to waste yet.
• 38:52
  SPEAKER_03: So and if you haven't eaten it, preserve it.
• 38:54
  SPEAKER_03: Yeah, whatever.
• 38:55
  SPEAKER_01: Throw it in the freezer.
• 38:56
  SPEAKER_01: If you have any questions, you can totally email us.
• 38:58
  SPEAKER_01: We can do a QA, maybe.
• 39:00
  SPEAKER_01: This would be a good one to do a QA on just for clarifications and stuff like that, whether it be for diabetes or or weight loss.
• 39:06
  SPEAKER_01: I mean, we both know about both of them, but we are both on GLP1s, we've both been on them for years.
• 39:11
  SPEAKER_03: Like I've been successful with it, but I will say, like, when I first started it, I knew better, but I ate really shitty and I didn't feel well.
• 39:18
  SPEAKER_01: Well, that's actually one that I didn't go over in the chronic fatigue.
• 39:21
  SPEAKER_01: Fatigue.
• 39:21
  SPEAKER_01: So if anybody knows me, they know I'm a sleepy girl.
• 39:24
  SPEAKER_01: I'm a sleepy girl.
• 39:25
  SPEAKER_01: So, and that got way worse when I went on this because I just wasn't eating enough.
• 39:29
  SPEAKER_01: Energy comes from food.
• 39:31
  SPEAKER_01: So if you're not eating, like you need to eat, and especially if you want to lose weight, you have to eat to lose weight.
• 39:36
  SPEAKER_01: It sounds kind of like counterintuitive, but you need protein to lose weight, or else your body just yeah, body just keeps it and stores it because thinks you're in a starvation.
• 39:45
  SPEAKER_01: Starvation mode.
• 39:46
  SPEAKER_01: Yeah.
• 39:47
  SPEAKER_01: Going through the flu pant, the Spanish flu.
• 39:49
  SPEAKER_01: Yeah.
• 39:49
  SPEAKER_03: Yeah.
• 39:50
  SPEAKER_03: Yeah.
• 39:51
  SPEAKER_03: So good action packed, information packed.
• 39:54
  SPEAKER_03: Sorry about that.
• 39:54
  SPEAKER_03: It's a little bit longer than before, but we'll uh we'll do something funner next time.
• 39:59
  SPEAKER_01: It's not so.
• 40:00
  SPEAKER_01: And we'll I'll be back with the homestead.
• 40:02
  SPEAKER_01: Sorry, this is my this is my jam, so yeah.
• 40:04
  SPEAKER_01: Maybe I'll talk about jams.
• 40:07
  SPEAKER_00: All right, until then.
• 40:09
  SPEAKER_00: Love you.
• 40:12
  SPEAKER_00: This podcast is reading.
• 40:15
  SPEAKER_00: Buddhist, buddhood, buddhose.
• 40:18
  SPEAKER_00: Loosely edited by us.
• 40:21
  SPEAKER_01: Thank you for joining us on Health and Homestead.
• 40:23
  SPEAKER_01: This podcast is a labor of love and healing for us in more ways than one.
• 40:27
  SPEAKER_01: So until next time, take care of yourself, pretend to what matters, and keep going.