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Latest / Decera Clinical Education Oncology Podcast

Rationale for NTRK Testing in Patients With Cancer

In this episode, George D. Demetri, MD, and Alexander Drilon, MD, discuss the biologic rationale behind testing for NTRK fusions in patients with various solid tumors, along with clinical strategies for testing. Topics include:

Differences between NTRK fusions vs gene mutations

Frequency of NTRK fusions by age and tumor type

When to test patients for NTRK fusions and interpreting reports

Methods of testing: multiplex gene testing, next-generation sequencing of DNA vs RNA, immunohistochemistry, and liquid biopsy

Presenters:

George D. Demetri, MD

Professor of Medicine

Harvard Medical School…

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