Latest / The Inspired Stories Podcast / Sean Cumiskey: From Global Hedge Funds to Saving Lives Through Biotech
Transcript
- 0:04Welcome to another edition of the Inspired Stories podcast,
- 0:08where leaders share their experiences so we can learn from
- 0:11their successes and be inspired by how they've overcome
- 0:14adversity. My name is Anthony Kotaspodi,
- 0:17and today's guest is Sean Comiskey.
- 0:19Sean is the Head of Investor Relations at Omega Fund
- 0:23Management, a global life sciences investment firm based
- 0:27in Boston that supports early to late stage biotech and
- 0:31healthcare ventures. Founded in 2004, Omega Funds has
- 0:35raised $2.5 billion to invest in exceptional entrepreneurs
- 0:41developing innovative products across multiple therapeutic
- 0:45areas, including oncology, immunology, rare diseases,
- 0:50medical devices, and precision medicine, aiming to help bring
- 0:54groundbreaking treatments to patients worldwide.
- 0:58Neshawn has a long history in investor relations and strategic
- 1:02development, having held key roles at prominent hedge funds
- 1:05and investment firms at How do I Say This?
- 1:09Why Hang Capital? It's a it's actually, it's
- 1:12actually Yeehong in. Yeehong Capital.
- 1:15Management is it's Mandarin for perseverance, most people
- 1:19Yeehang, but it's Yeehong. Yeehong Capital Management He
- 1:23helped grow assets under management from 350 million to
- 1:27over 3.5 billion. He also LED business development
- 1:32and product development at Farallon Capital Management, a
- 1:35$40 billion global fund, and directed global investor
- 1:39relations at York Capital Management.
- 1:41His previous experience encompasses senior roles in
- 1:44banking and investment consulting as well as asset
- 1:48management. Sean joined Omega in March 2024,
- 1:52bringing his deep expertise in capital development and business
- 1:55strategy to the team. Now before we get into all that
- 1:59good stuff, today's episode is brought to you by my company,
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- 2:38AD back benefits.com. All right, back to our guest
- 2:41today, Head of Investor in Relations at Omega Fund
- 2:44Management, Sean Kaminsky. Thanks for making the time to
- 2:47Share your story today. It's a pleasure to be here,
- 2:49Anthony. Thank you for having me on.
- 2:51Yeah. So, OK.
- 2:53How did you first get your start in this world of, call it, asset
- 2:56management? It was also a long time ago, I
- 2:59think initially when I was an undergrad and, and was fishing
- 3:03for things to do, I thought I would want to be a lawyer.
- 3:06I was, I was always writing, always like to engage in
- 3:12situations where there was debate and discussion and, and,
- 3:15and was a good student in terms of like English and liberal arts
- 3:17and, and those types of, you know, kind of skills kind of
- 3:19lead you toward law school. And, but I worked for a law firm
- 3:23for a summer as an undergraduate and I realized the law is not,
- 3:28there's the law that you think it, you're, you might be getting
- 3:30to and there's what being a lawyer really is.
- 3:32And I realized that that being a lawyer was probably not, you
- 3:36know, in, in, you know, in my future in terms of what I, what
- 3:39I kind of like to do. Just like too much like reading
- 3:42too much pouring through. Like boring case law.
- 3:44Especially like big law firms, it is, you know, the associate
- 3:47to, you know, the associate track is, is, is really a grind.
- 3:50And we used to call it being on semi colon patrol, right?
- 3:52You're just kind of reviewing documents and things all day
- 3:55long. And, and that is fine, But I
- 3:56have another side of my personality, which is very much
- 3:59kind of forward facing and like interact with people as opposed
- 4:02to kind of documents. And so, you know, at that point
- 4:05I kind of thought, well, you know, let's think maybe about,
- 4:07you know, kind of finance or, or kind of something that was more
- 4:10kind of money oriented, even though I didn't have much
- 4:11experience in that. But I was fortunate to get into
- 4:14a, a bank training program out of undergraduate.
- 4:17And then afterward was able to work in kind of the, the private
- 4:20Bank of the old Chase Manhattan Bank, which is kind of managing
- 4:23assets for kind of high net worth individuals and families.
- 4:26And as opposed to, let's say, investment banking or, or
- 4:29commercial banking, it was less transactional, more relationship
- 4:31oriented. And ultimately the fees that you
- 4:34generate are more in line with the value that you drive for the
- 4:36client. So it was much more aligned with
- 4:38kind of how I think of the world as opposed to just kind of
- 4:41selling and kind of pushing product and and and being
- 4:43transaction oriented. Anything wrong with that?
- 4:46But I really like kind of being on the side of the client.
- 4:49And so that really kind of got me started in asset management.
- 4:52OK, so before we get to what you're doing current day with
- 4:56Omega Funds, let's pick out one of your career stops along the
- 5:01way that you would consider to be the most formidable for you
- 5:05and why. What is it that you gain from
- 5:07that experience? I would say probably I was on
- 5:12the investment committee and management committee at a firm
- 5:15called IV Asset Management, which was a global fund of funds
- 5:18manager at based in New York. So essentially we managed hedge
- 5:22fund portfolios, you know, taking different hedge fund
- 5:25managers and putting them into to a, you know, groups of
- 5:27portfolios for insurance companies, for kind of
- 5:30sovereigns, for pension funds, etcetera.
- 5:32And we had a pretty large global organization managed about 16
- 5:36billion head offices in San Francisco, New York, London,
- 5:40Tokyo and Hong Kong. And so it was a large complex
- 5:44organization basically engaging in very, very kind of
- 5:48sophisticated investment strategies in addition to the
- 5:51the management and kind of, you know, business challenges that
- 5:54you have across the line. And so we managed, you know, was
- 5:58kind of in that 2, 2003 through 2000 kind of 11 type period
- 6:03where you had significant global growth, but then you had a
- 6:06financial crisis in 2008. And so it kind of taught me to
- 6:10manage individual conflicting agendas, to be able to manage
- 6:14clients and products in a time of growth and in a time of
- 6:17stress and actually learning some important lessons along the
- 6:21way in terms of what really makes leadership and what kind
- 6:24of passes is leadership in in our business.
- 6:27And so I was able to be involved in a lot of different
- 6:30strategies, a lot of different types of asset classes and with
- 6:33clients, you know, all over the world with different priorities
- 6:36and different perspectives, in addition to having managed a
- 6:39global team. So it was challenging on a
- 6:41number of fronts and I learned a a lot of very, very important
- 6:44lessons from that time. Let's pick out just one.
- 6:51You know, I think there's different types of, you know, in
- 6:54terms of lessons as it relates to either people or that
- 6:57there's, you know, people lessons, there's business
- 6:59lessons, there's kind of strategy, kind of, you know,
- 7:02tactical lessons. You know, I would say during
- 7:05the, the most consistent thing during that time that that I
- 7:08leaned on was just transparency and candor and communication
- 7:13within the organization in terms of, you know, people are
- 7:16incredibly intuitive in terms of what's kind of happening,
- 7:19whether it's good or bad. And so providing, you know, the,
- 7:23I would say the, the clarity and perspective that many people
- 7:29need if they're working underneath you.
- 7:31And the other thing is in times of stress, you know, if you can,
- 7:35you know, kind of keep your head while others are losing theirs,
- 7:39that is a significant, you know, kind of advantage that you can
- 7:44kind of take with you over time because it is very easy to get
- 7:47caught up in the day-to-day, especially when things are not
- 7:49going the way that you want. And if you have that bleed into
- 7:52your, the interactions with your people or your family or, or, or
- 7:55other people in your life, it can kind of start rolling
- 7:58downhill pretty quickly. And so, you know, you have to
- 8:01kind of step back and realize the sun will always come out
- 8:03tomorrow, even if it doesn't seem that way.
- 8:06And, and in managing people in terms of being able to be candid
- 8:11with people about what is going on with the business, whether
- 8:13it's on the positive side or, or when things aren't going so
- 8:15well. Do you think you're just sort of
- 8:18wired naturally to have this perspective?
- 8:21Did you have some mentors along the way that coached you or
- 8:24maybe a course that kind of like steered you towards this thought
- 8:27process? Well, when I was, when I was at
- 8:29Ivy, I had, we had a, you know, a very good executive team And
- 8:33one of the things that we were all assigned as part of the
- 8:36management committee, we were assigned a management coach.
- 8:39And just because it was, seemed to be a good thing.
- 8:42There were six of us that were on this committee managing a
- 8:44pretty big business. And initially I thought a
- 8:46management coach, you know, that's just going to tell you
- 8:48basic stuff like be honest with your people or, you know, make
- 8:51sure you make sure you credit where credit is due and things
- 8:53like that. I was just very, I, I, I, I
- 8:55wasn't anti or against the concept.
- 8:58I just didn't see that, you know, the, the, the real need,
- 9:01which was a blind spot. And after spending time with,
- 9:06you know, the, the individual management coach that I was
- 9:07assigned to, they really helped me kind of look inside myself
- 9:12and strengthen my good habits. I did have and kind of wean
- 9:17myself off of the, of the habits or practices I had that were
- 9:20probably less constructive that I just didn't see.
- 9:22And so I think it kind of made me aware that you can always
- 9:27receive feedback and improve, even if it's something that you
- 9:31think is very, very straightforward.
- 9:33And you know, being more introspective and really
- 9:36assessing kind of your, your own strengths and weaknesses and
- 9:40your own true interests is is very, very helpful.
- 9:44And you know, that really kind of set me on the path to where I
- 9:47am now in terms I realize. What are the things that really
- 9:49make you get out of bed and they get you excited about in the
- 9:51morning about your business and are you doing them everyday?
- 9:55What are the things that get you excited to get out of bed
- 9:58everyday, Sean? Well, I think, you know,
- 9:59there's, you know, in, in our business like an asset
- 10:02management or hedge funds or, or venture capital or, or you know,
- 10:05what people have called alternative investment
- 10:07management. But really where you have kind
- 10:10of the, the most profitable firms, the most competitive
- 10:13people, the most difficult markets or, or problems and the
- 10:17most intelligent clients. So it's challenging in all
- 10:19fronts, which is great, but there's a typically, you know,
- 10:22kind of a couple of tracks that you can take.
- 10:24You know, 1 is kind of maybe just being more of a manager,
- 10:27right? Managing business unit, managing
- 10:29people, managing processes. The other side is really kind of
- 10:32being involved with clients and products.
- 10:34And we're kind of the, the rubber really hits the road on
- 10:36the revenue side. And I found that I was kind of
- 10:38being more kind of not through any kind of, I would say
- 10:44conscious effort on my part moving more toward the
- 10:47management side when I really enjoyed the client and the
- 10:50product side much more. And so getting out of the things
- 10:53that Get Me Out of bed or helping to drive revenue to come
- 10:56up with new innovative products to work with clients, to bring
- 10:59business into the firm, to keep business from leaving the firm,
- 11:02to be really being on the front lines as opposed to being in in
- 11:06staff meetings all day. Now there's some people that are
- 11:08phenomenal at that, right? You have to be, you have to be
- 11:10really be honest about what you're good at.
- 11:14And there are some people up within very large organizations
- 11:16that are phenomenal at kind of surfing the bureaucracy, if you
- 11:19want to say that, or kind of taming the bureaucracy and, and,
- 11:22and being in meetings all day and making them productive.
- 11:24I'm just not that way. I'd much rather be on the front
- 11:28lines. And so it was a real kind of, I
- 11:32would say, aha moment for me in terms of where I want to spend
- 11:36my time, if I can, where I'm most effective and what are the
- 11:40things that get me, Get Me Out of bed in the morning.
- 11:42And it's really the client, the product size as opposed to being
- 11:46a full time manager, Not that I, you know, I'm opposed to
- 11:49managing. I've managed teams and I, I
- 11:51think I've been OK at it. But it's again, it's, it's more
- 11:54of the, you know, kind of the, the front end of the business as
- 11:58opposed to kind of managing the structure, if you will.
- 12:02So how did the door open for you to join Omega Funds?
- 12:05So I was at a firm called Yeon Capital Management, which I had
- 12:09joined when they were about $350 million.
- 12:12I wanted to do something entrepreneurial at that time of
- 12:14the business, which for reasons we can talk about later, but and
- 12:18was able to grow them to, you know, kind of 3 1/2 billion.
- 12:20I was the Co chief operating officer and kind of tenured
- 12:23faculty, if you will, was not looking to, to, to go anywhere,
- 12:27But I've always had a very kind of personal interest in biotech
- 12:30and life science going back, you know, many years I've been
- 12:33personally invested life science funds.
- 12:36You know, I've, I've seen kind of the impact that, you know,
- 12:38new medicines and therapies have on, on, on patients and I've
- 12:41always been very interested in that.
- 12:43And the opportunity came up at Omega when they were doing a
- 12:46search to hire someone to really kind of bring a, a more senior
- 12:51perspective and, and, and, you know, to the, the front end of
- 12:55their business in, in life sciences.
- 12:57And I was recommended, a friend of mine in, in Silicon Valley
- 13:01recommended that they speak to me.
- 13:02I wasn't looking to leave, but the more that I talked with
- 13:05them, the more I realized that the unique set of circumstances
- 13:08represented by Omega was something that may not come
- 13:11around again. So I was able to kind of put
- 13:13everything that I had, you know, kind of learned and practiced
- 13:16over time, you know, into a firm that from the investment process
- 13:20really makes a difference in, in people's lives.
- 13:23So it's very much, you know, doing well by doing good.
- 13:27And so that had tremendous amount of appeal to me.
- 13:29And, and, and so I was, it was once I got to that decision
- 13:33point, it was pretty clear that if I hadn't taken this step, I
- 13:36would have always regretted it. So with this particular
- 13:40opportunity, it was a friend that recommended you.
- 13:42As I look back over your career path, lots of great stops along
- 13:46the way. Were you headhunted for those?
- 13:48Did you apply cold? Were there was also
- 13:51recommendations, referrals where you knew somebody there?
- 13:54It's almost 100% of the time people that I know in the
- 13:57industry, you know, and you know, they're always, you know,
- 14:02I, I would say when people are looking to move from, you know,
- 14:06whatever job it might be, you know, there, there's either a
- 14:09push or a pull, right? They're either being pushed
- 14:12because they just either the internal dynamics, maybe they
- 14:14don't like their boss or just there's something about the
- 14:16current role that is just not, is unbearable or just that they
- 14:20want to look elsewhere versus the pull where there's something
- 14:23very, very attractive that they're very interested in
- 14:26someplace else that lines up well with their skills and and
- 14:29makes sense. I've always been kind of pulled
- 14:30toward things as opposed to, Hey, I want to get promoted.
- 14:33So I go to another firm that does the same thing, You know,
- 14:35I'll be slightly more senior. And so really from us, from my
- 14:40experience, it's just been, you know, my own industry network
- 14:42and, and people that I know. And so which is very, very
- 14:46important. You learn over time because in
- 14:48an industry like ours, which you're only, you know, it's
- 14:52truly 6° of separation, if not fewer degrees of separation that
- 14:55people have. Everyone knows somebody that's
- 14:58senior in our industry that has worked with you or worked for
- 15:00you or or has interacted with you as a client or, you know, a,
- 15:04a service provider. Everyone carries with them a, a
- 15:07citizenship grade essentially. And you know, I would, I always,
- 15:12you know, advise, especially kind of younger, you know,
- 15:15professionals or people that ask me for advice.
- 15:17You need to really, really pay attention to that in terms of
- 15:19how you treat people, how you interact with the outside world,
- 15:23how you deal with stress, because ultimately good
- 15:27opportunities will find you when you have a high citizenship
- 15:31grade and high integrity and high work ethic, They those,
- 15:33those opportunities will find you.
- 15:34You don't necessarily have to look for them yourself.
- 15:36And there are a lot of people that have just kind of, you
- 15:39know, kind of blown themselves up through certain types of
- 15:40behavior that, you know, that, you know, that may not be an
- 15:43indicative of who they are, but you know, it, it leaves it
- 15:45leaves an, an imprint on the way people think of you.
- 15:47Yeah. OK.
- 15:49So let's talk more specifically breakdown what it is that you
- 15:52guys do there to make a funds plain English.
- 15:55So in plain English, you know we are a venture capital firm.
- 15:58And so Simply put, what means is, is, is we provide capital to
- 16:03start up smaller companies that in our case not investing in
- 16:07technology or social media or the, the, the venture company
- 16:11might be familiar with, but in companies that are developing
- 16:14therapeutic solutions that we call unmet medical needs.
- 16:17So essentially companies that are developing new types of
- 16:20therapeutic drugs where there could be a small molecule, which
- 16:23is like a pill or a biologic like an injectable or even cell
- 16:28and gene therapy and then also medical devices as well.
- 16:32Ultimately, we're looking to improve the standard of care and
- 16:38make patients lives, you know, their outcome is better.
- 16:43And so you know, we operate, we invest in companies that are,
- 16:47you know, across therapeutic areas like oncology or
- 16:50immunology or the cardio metabolic space, things like
- 16:52that. And also on some, some medical
- 16:55devices as well. We've you know, invested in
- 16:57companies that are improving kind of insulin pumps or heart
- 17:01monitors for those that have at risk of studying cardiac arrest
- 17:04or things like that. And so we've been quite
- 17:07successful. We've developed, you know, 52
- 17:10kind of FDA approved products that have improved the lives of
- 17:13patients. But it is, it is, it's very
- 17:16complicated. You know, think about the, the
- 17:18science is very different across different disease areas and
- 17:21there's very high barriers to entry into business, which is
- 17:24one of the things that I like as well, which we can talk about in
- 17:26terms of the difference between biotech versus others.
- 17:28But essentially we're developing drugs and devices to improve the
- 17:30lives of patients. Yeah, wow, that is a great
- 17:34reason to get out of bed every morning, isn't it?
- 17:37It's, you know, it is, it is really cool.
- 17:38I think, you know, it's the, the failure rate obviously in, in,
- 17:41in our business, in drug development is quite high.
- 17:43You know, 90% of the, the drugs that you know, don't necessarily
- 17:47make it. And that's true for a lot of
- 17:48start-ups, right as well. But, and life science is
- 17:50particularly high. But the very nice thing is when
- 17:54our companies succeed, it is unambiguously good for humanity,
- 18:00right? We're not.
- 18:00And, and, and I don't want to sound like I am, you know, kind
- 18:04of disparaging kind of normal kind of tech investing, but
- 18:08we're not, we're not looking to industrialize mental illness or
- 18:11FOMO. We're not trying to incent
- 18:14consumers to spend money they have on things they don't need.
- 18:16We're not, you know, trying to attract people to sports betting
- 18:18platforms. And, and, you know, we're
- 18:20creating kind of automated solutions that throw workers out
- 18:23of work. And, and so there's a lot of
- 18:24unintended consequences that comes with new technology that
- 18:26we've seen. But in our case, it's
- 18:28unambiguously good in terms of improving the standard of care
- 18:32or developing new standards of care for a lot of really
- 18:35horrible diseases. You know, for example, we have a
- 18:37a company right now that's working on a treatment for
- 18:40pulmonary fibrosis, which is a really horrible disease that
- 18:44once you know, many cases you're diagnosed, you might have four
- 18:47to five years. And the current standard of care
- 18:48for some of these severe elements of the disease just
- 18:52kind of manages the decline, right.
- 18:55And so we have a company that actually for the first time is,
- 18:57is actually has shown some evidence where they can reverse
- 19:00the fibrosis and, and restore lung functioning, which again,
- 19:03it's a long way to go. It's a very long path, right,
- 19:05for these things to work. But that's just truly, truly
- 19:07kind of cool to see. Is there an example of something
- 19:11that's in the market helping folks right now that would be
- 19:13fun to talk about? So there's a number of things
- 19:17that we've that we've done that have been, you know, had
- 19:19significant impact. So, you know, with these
- 19:22companies, in many cases, like we don't, we won't take them all
- 19:24the way through the clinic and approval.
- 19:26Typically our job is to get them is to, to have the, the, the,
- 19:31the companies develop the drug to go through maybe phase two,
- 19:34phase one trials. And in many cases, those
- 19:36companies will either go public as an IPO to raise funds to
- 19:40further develop the therapy, or more often they will be
- 19:42purchased by large pharma companies who then will take
- 19:45them through the stage, you know, stage 3 development and
- 19:47the regulatory approvals. What has happened?
- 19:49The reason why, you know, we have firms like like ours is
- 19:53that, you know, large pharma companies are not necessarily
- 19:58good at developing their own drugs.
- 20:00You know, they're very large bureaucratic organizations.
- 20:02They can't really move as quickly.
- 20:03And so 20 years ago, you know, maybe 50% of the clinical
- 20:08trials, meaning that the, the trials where they're testing the
- 20:10drugs in patients, we talk that in the clinic, 50% of those
- 20:13clinical trials were done by small biotech companies.
- 20:16Today it's 75%. And so large pharma has largely
- 20:20outsourced the development and creation of new drugs to small
- 20:23biotech companies, which are the the companies that we fund.
- 20:28OK. What do you think sets you guys
- 20:30apart? Like you know you've mentioned
- 20:32the 52 impactful medical products market, the FDA
- 20:36approvals. How are you guys different from
- 20:38some of the other biotech and healthcare funds out there?
- 20:42It's a, it's a good question. I think, you know, there's the
- 20:46short answer is, is there are a lot of very good firms, you
- 20:48know, in our business. I think in the way that that we
- 20:52look at it as a couple different ways that would have made us
- 20:54successful. It's not that the answer isn't
- 20:56like, hey, we're smarter than everyone else or our scientists
- 20:59or our pH DS are, are more diligent.
- 21:01You know, all firms in our business have really, really
- 21:03good people. You know, where we, I think,
- 21:06differentiate ourselves is, you know, the name of the, the firm
- 21:10is Omega, which is the last letter of the Greek alphabet.
- 21:13And So what that means is we focus on what the end result is
- 21:16like what is, what is the problem we're trying to solve?
- 21:19Meaning that we don't necessarily say, OK, we have
- 21:21some scientists coming out of a lab in, you know, Cambridge or,
- 21:24or, or someplace and they have some real cool science.
- 21:27They're not quite sure what the indication or disease they might
- 21:30be able to cure with this, but it's very interesting.
- 21:32And, and so we'll, we'll fund this kind of science experiment.
- 21:35We don't really do that because we want to know what the actual
- 21:37product is going to be like. What are we trying to solve for?
- 21:40The other thing is that we work as a team.
- 21:43Many venture firms are not firms per say.
- 21:47They're more, as I would describe it, a loosely aligned
- 21:51confederation of interest, meaning that you have one
- 21:53partner, 1 senior investment person working with three or
- 21:55four associates maybe. And that team basically does
- 21:58everything for that portfolio company.
- 22:00You know, the transaction, the financing, they're on the board,
- 22:03they advise the company. And you can do that in, in tech
- 22:07or software investing, but in biotech, it's very, very
- 22:11complicated. Not only is it the initial proof
- 22:13of concept or the, the Phase 1, you know, kind of phase one data
- 22:17that trials that you're running, it's also the regulatory
- 22:20interface, it's financing the company.
- 22:22There's the clinical trial strategy.
- 22:24Once you get into the clinic and the patients, how you design the
- 22:26trials, where you do the trials. There's the chemistry
- 22:29manufacturing controls, we call CMC, which is, you know, once
- 22:33you've proven a company, a compact and work in the clinic,
- 22:35you've got to be able to manufacture it at a scale enough
- 22:37for, to, for phase three trials. So there's a whole bunch of
- 22:40things that are very, very important and typically not one
- 22:42person knows everyone or everything.
- 22:45And so the way we work is, it is as a team, we will bring in the
- 22:49various Omega experts from across the firm, no matter whose
- 22:52deal it is to make sure we have the best outcome for the
- 22:55company. And so because of that, our
- 22:57portfolio companies are supported by our entire
- 22:59organization because the way that we're all compensated is on
- 23:03the the portfolio, how well the portfolio does.
- 23:05So we all have the best incentive to make sure that we
- 23:07have the best outcome for each company.
- 23:10And so we're able to work across the firm and across disciplines
- 23:12in a way that helps the company get through the clinic more
- 23:16efficiently and more effectively.
- 23:18And so I think when you think about combine the product first
- 23:20approach and so the 52 products is a huge number for a firm of
- 23:24our size. And the fact that we're able to
- 23:26work as a team across the firm makes a real difference in terms
- 23:30of our investment outcomes. I want to hear a little bit
- 23:36more, we'll come back to what you're doing at Omega, but it's
- 23:40just keeps rattling around in my head what you did in, in terms
- 23:43of at your previous role growing assets from 350 million to 3.5
- 23:49billion, What were the key ingredients in building that
- 23:54investor trust to ensure that kind of growth?
- 23:58Well, first thing is, you know, they're, they're you have to
- 24:01have kind of quality of relationships and, and that it
- 24:06goes, again, it goes back to the citizenship grade.
- 24:08So there's, there's a number of things that have to kind of
- 24:10interface, because ultimately you need to be able to translate
- 24:13kind of what you're doing in a way that is attractive to those
- 24:17investors that have interest in the area that you know, that
- 24:20that, that your firm invests. But ultimately, you know, one of
- 24:23the one of the key things, and this is something that I always
- 24:25kind of again, emphasize to, to younger professionals is kind of
- 24:28your citizenship grade. You know, I work at some very
- 24:30kind of large, well known firms and when I took a, a kind of
- 24:34detour to work for Yi Hung, which was a, a, a smaller asset
- 24:37manager, there's always the question it will investors, did
- 24:41they respect you or did they respect the seat that you're in?
- 24:43Meaning that, let's say, you know, to make it more, you know,
- 24:47concrete or, or, or a better example for the, you know, kind
- 24:50of the, the person on the street, Let's say you're, you're
- 24:53an executive at Alphabet or, or Meta or one of these large tech
- 24:57companies. And you know, you everybody, of
- 25:00course, you're business partners and your clients, you know, kind
- 25:03of will, will, will have some sort of difference just because
- 25:06of the, the power of the company itself.
- 25:07Then you go do something that's much smaller.
- 25:09Are you going to still have that kind of respect outside the
- 25:12organization that you were at versus when you were at the,
- 25:15the, the big platform? And so the key thing for many
- 25:18people is they will work at a very large, successful firm and
- 25:21think they want to do something more entrepreneurial, go to a
- 25:23smaller asset management firm. They can't replicate the success
- 25:26because they didn't have the quite the the citizenship
- 25:29development they might they should have when they're at the
- 25:31larger firm. And so for me, it was being able
- 25:35to lean on those relationships that I've built over time to be
- 25:38able to properly represent what we're doing at Yihan, which was
- 25:41complicated, more Asia focus, a little bit more opaque than many
- 25:46folks were used to. And being able to explain that
- 25:48in a way that would, you know, be aligned with kind of those
- 25:52investors that had an interest in investing in that part of the
- 25:54world. So a lot of it is translating a,
- 25:57a more complicated, you know, investment thesis or investment
- 26:00concept in a way that is actionable to potential
- 26:04investors. While, you know, again, leaning
- 26:07on that, that that relationship and that trust because many
- 26:10people had dealt with me before and other firms and knew that I
- 26:13wasn't going to just look to just, you know, kind of say
- 26:18whatever I needed to say to, to get them interested in, in, in,
- 26:21in the fund we're running at EON.
- 26:23So how well do you understand the tech side of the companies
- 26:29that you're investing in versus, I mean, it strikes me that
- 26:31you're clearly a smart guy, you understand the investment
- 26:34strategy side of it, but how well do you understand the the
- 26:39tech side of what you guys are investing in?
- 26:42And how much do your investors, your LP's understand about the
- 26:47tech side and is that really important?
- 26:50It's a good question and and and and very relevant.
- 26:54As I think about my career, I've always been.
- 26:55I've always gravitated toward complexity.
- 26:58Things that are more complicated might be a little more difficult
- 27:00to understand at first blush. Because when you're in investor
- 27:04relations or fundraising or, or or kind of client facing role,
- 27:08the ability to translate kind of complicated concepts and
- 27:13situations in a way that is understandable and actionable
- 27:18and and truthful right to to investors is a significant
- 27:23advantage. And I've always kind of
- 27:25gravitated to those more complicated situations because
- 27:28it allows me to stand out a bit more.
- 27:29I guess you would say, think about kind of where you, you
- 27:32know, kind of really have have excelled in the past.
- 27:34And so the previous terms I worked at were all kind of
- 27:36global multi asset firms, very complicated businesses, which
- 27:40were great platforms. And for someone like myself that
- 27:43likes to learn about a lot and, and, and, and be able to
- 27:45synthesize that, synthesize that, excuse me for, you know,
- 27:49kind of investors. And so when we think about what
- 27:52we're doing here at Omega in terms of life science and
- 27:55biotechnology, it's very complicated.
- 27:57And, you know, you really need to be able to meet the investors
- 28:00where they are. You know, if they have interest
- 28:03in kind of medical science but maybe aren't as deep in oncology
- 28:06or what we're doing with specific companies, you need to
- 28:08be able to make sure you can translate that for them in a way
- 28:11that makes it understandable. Likewise, for those that are
- 28:14really, really deep in the science, you need to be able to
- 28:16make sure that you can meet them where they are.
- 28:18And if they kind of outstrip what I know, because I don't
- 28:22know everything, you need to be able to make sure that you pair
- 28:24them with the right people to firm that can get them the
- 28:26answer they need. And so that becomes very
- 28:28important because you need to kind of vary that level of
- 28:32information depending on on who you're with.
- 28:34We have clients that are many types, you know, wealthy
- 28:37families that are look to invest to make an impact in other
- 28:40impact oriented investors. It's what we do in Healthcare is
- 28:43is extremely important to them, but they're not healthcare
- 28:45experts. We also have a lot of medical
- 28:49foundations and hospitals that are investors.
- 28:52They know the science and you know, we also have a, a few kind
- 28:55of pharma companies and, and, and other kind of pharmaceutical
- 28:59entities that are also investors and they're truly expert in
- 29:02those cases. I will, I'm really just the
- 29:04major deed of the firm. I will facilitate those
- 29:07conversations with the really, really deep experts in those
- 29:09fields. I'm not trying to, to hold
- 29:12myself out as a PhD in neuroscience because I'm not,
- 29:15but we have plenty of them here and I make sure I'll be able to
- 29:18call on them when needed, which is also very, very important in
- 29:20our roles. You need to be able to extract
- 29:23the expertise in the firm and place in front of the client
- 29:25when it's necessary in a manner that is, you know, very, very
- 29:30efficient and and seamless. So you guys are not currently
- 29:35raising a fund, but as I understand it, you recently
- 29:39closed 1 Omega 8. Tell us about that.
- 29:42What did you raise, what was the target?
- 29:46So our target. Was 600 million, we raised just
- 29:49under 650, so 647. And so that was just about the
- 29:53same size that we raised back in 2021 and 2021, if you recall.
- 29:58It's kind of the, the peak of the kind of COVID everything
- 30:02bubble, right? Everything was going up and,
- 30:04and, and raising capital there was, you know what, what wasn't
- 30:07as difficult. But in the intervening three to
- 30:10five years and you've seen this across venture, private equity,
- 30:13LBO, you know, biotech fundraising has, has come down
- 30:18quite a bit. And part of that is because
- 30:20limited partners or the investors have not received the
- 30:23distributions that they would expect from their private equity
- 30:27investments, meaning the cash realizations haven't come back
- 30:29to them, whether it's via IP, OS or M&A transactions, etcetera.
- 30:34And so as a result, biotech fundraising was down about 70%
- 30:38from the peak in 2021. So for us, it's #1 being able to
- 30:45make sure that we have these very, very kind of solid
- 30:48relationships with our clients. That means communicating with
- 30:50them through both good times and bad.
- 30:52And when things aren't necessarily moving in the
- 30:54direction you want, being just, you know, candid about that and
- 30:56and giving them a real honest look at what's happening in the
- 30:59portfolios, because at the end of the day, they're all
- 31:02professional investors. They just need to know that, you
- 31:05know, you're aware of what's happening and that you can
- 31:07communicate kind of the both the pluses and minuses of what's of
- 31:09what's going on. But more importantly, we were
- 31:11able to deliver what we call DPI, which is the essentially
- 31:16cash returns to investors. So during the kind of three-year
- 31:20period where, you know, January 2022 to middle of last year
- 31:25where a lot of investors weren't receiving, you know, cash
- 31:28distributions from their venture firms, you know, we distributed
- 31:30almost $900 million of of of capital back to our LP's.
- 31:34We had 14 M&A transactions 6 / a billion and we had like 9 IPOs
- 31:39in a period where no one is really doing anything.
- 31:41And the reason why is it's not 'cause, you know, again, we, you
- 31:44know, and that really stand out that, that that stands out.
- 31:47And so we were able to, you know, it was real, the real
- 31:49proof of concept. Because at the end of the day,
- 31:51when you are able to invest in or you have a product or a
- 31:57therapy where it's a device or or a drug that has the data that
- 32:03indicates that it's going to be effective against a significant
- 32:06unmet medical need in any of these disease areas that has
- 32:09value in any environment. And the reason why is most of
- 32:14our exits, over half have been M and A transactions to pharma
- 32:17because we develop drugs that work and pharmaceutical
- 32:21companies, as you know, always have patent expirations and loss
- 32:24of exclusivity. So they need to replace their
- 32:25pipelines with newer drugs. And as I mentioned earlier, they
- 32:29outsource a lot of that to small biotech companies.
- 32:31So they're always serial acquirers.
- 32:33So they're, they're I guess in demand curve is inelastic as it
- 32:37relates to acquiring new assets as long as you have the data.
- 32:41So it doesn't. The great thing about our
- 32:42business is that it doesn't matter what's happening with
- 32:45interest rates as much or what's happening in the macro economy
- 32:49or with Ukraine and Russia or things like that.
- 32:52As long as we're able to develop these types of successful
- 32:56therapeutics that has value in any market, particularly to
- 32:59pharma. And we saw that in the last 2
- 33:011/2 years, given the amount of kind of exits and liquidity
- 33:04we're able to generate for our investors.
- 33:05So you include, you know, you, you tack on the fact that we're
- 33:09a very credible organization that we communicate very clearly
- 33:12with our investors. We're always looking to educate.
- 33:15We're able to distribute capital and return cash to our investors
- 33:20in a time when no one else was. All of those factors enabled us
- 33:23to to raise additional capital, especially with newer investors
- 33:27that were new to Omega. And so as it was a combination
- 33:30of things that enable us to be successful.
- 33:32But but we're we're, we're quite happy the way it turned out.
- 33:35So typically the way a company gets valued is here's the
- 33:42revenue, right? And depending on what field
- 33:44you're in, here's sort of a multiple of what your EBITDA is,
- 33:48for example. It strikes me though that in the
- 33:53area that you play in that maybe there's a different type of
- 33:57formula that's used. And tell me if I'm right or
- 34:00wrong here, because perhaps the company, they've got this great
- 34:03product, maybe they're starting to sell it, maybe they aren't
- 34:07selling it yet, but they know that it works.
- 34:09And so revenue numbers don't really assign the true value to
- 34:13it. Yes, that is, that is true.
- 34:19You know, I, I would say that one of the ways, if you look, if
- 34:23you think about our, our, our, our companies, you know, we, we
- 34:27invest in, you know, they're, they're cash burning science
- 34:30experiments ultimately is what they are, right?
- 34:33They, they, they have no revenues, right.
- 34:35They're burning cash and it's, and it's expensive to get a, a
- 34:38new drug in, in into the clinic, you know, and that's, that's on
- 34:41the drug side separately from the device side.
- 34:43So medical devices do have revenues.
- 34:45So if you're on the device side, it's it's very much like a a
- 34:50typical company that you would value right, kind of multiple of
- 34:52sales. You see the traction they're
- 34:53getting in the market, you know, profit margins, etcetera,
- 34:56because they're they're commercial stage companies.
- 34:58So that that's more kind of the traditional valuation metrics
- 35:02applied to those companies. But for the therapeutic and the
- 35:04device companies, you know, the valuation is really going to be
- 35:07based on, you know, kind of the, the maturity of the company in
- 35:13terms of how early it is. Is it phase one?
- 35:15Is it Phase 2 is about to go into phase three.
- 35:18The type of indication? Is it a very, very large disease
- 35:22area that has significant, you know, kind of, you know,
- 35:26commercial potential or is it something that's very more niche
- 35:30like kind of rare disease? And also, you know, kind of what
- 35:34ultimately the in many cases for the pharma companies, what the
- 35:37acquirers are willing to pay, which may not be related to the
- 35:41stage of the company at all, but their view of the attractiveness
- 35:45of the asset vis A vis their current portfolio of companies.
- 35:47So the valuation on the private side of the, of the, of the
- 35:51therapeutic companies is, is much more an art, you know, than
- 35:54a science. And it's much more related to
- 35:55the data and the indication. How good is the data?
- 35:58How much does it improve the standard of care?
- 36:00Or is it a first in class, best in class therapy against
- 36:03something that is, you know, a pernicious and, and kind of
- 36:06widespread type of disease? And so, you know, when you think
- 36:10about, you know, we don't think about like Tams or things like
- 36:12that in terms of, you know, 'cause ultimately for the, the,
- 36:16the, the, you know, the, the, the potential market for what we
- 36:20do is every person on the planet, cause everyone gets
- 36:22sick, unfortunately. But within certain disease areas
- 36:25like large oncology or immunology, there's these very
- 36:27large indications like pulmonary fibrosis that I mentioned that
- 36:31are, you know, have significant commercial potential if you're
- 36:34able to develop a therapy. And so the pharma companies will
- 36:37evaluate on that. And if you're going public, they
- 36:39will also tend to look at what the potential application of
- 36:43this, of this, of this drug is going to be a blockbuster, over
- 36:46a billion dollars in sales. What do they think that may
- 36:48reach once they reach the phase two, phase three approval?
- 36:50So there's a lot of art and science in the valuation of
- 36:53these companies as opposed to just pure metrics that you might
- 36:55see in other other, other instances.
- 36:58Makes sense. Sean, tell us about how you.
- 37:02Sorry, what was that? I said I hope I made sense.
- 37:04I don't know. I don't know.
- 37:06I'm with you. I'm with you.
- 37:07Yeah. You know, I mean, some
- 37:08businesses are pretty cut and dry where it's like, you know, I
- 37:11used to be in the E com space for a while and you know, for a
- 37:14while those multiples were pretty low.
- 37:16And then they moved up during COVID when everybody wanted an E
- 37:19com business. And now they've they've come
- 37:21back down. SAS businesses have, you know,
- 37:24their own typical multiple manufacturing.
- 37:27And so yeah, just trying to get an idea of how this space works.
- 37:29And so it's, you know, what I'm hearing you say is on the device
- 37:32side of things. Yeah, there there's sort of more
- 37:35of that more traditional formula on a biologic on you know, some
- 37:39kind of a medication. It's a bit different, right.
- 37:42It's like how good's the because it's not gone to market yet in
- 37:45this case is that. True.
- 37:47Exactly. Exactly like how good, how good
- 37:48is the data, how robust is is is the data and what is the
- 37:53indication that you know that you are are are you know how
- 37:58large is, is the problem. So, you know, there's, there's a
- 38:00company that we incubated about four years ago, almost five
- 38:05years ago called Scorpion Therapeutics, which was in the
- 38:08oncology space. So this is a company that we
- 38:09incubated ourselves. We took the manager team from,
- 38:12you know, they had a white, they had a white sheet of paper.
- 38:14They wanted to go after certain types of, of hard to cure breast
- 38:17cancers. And so we funded them and helped
- 38:20build the company, build a commercial organization for
- 38:22them. And they were in the clinic, you
- 38:25know, testing within patients within three years, which is
- 38:27very, very quick. And then at the beginning of
- 38:29last year, they were acquired by their lead asset was acquired by
- 38:33Eli Lilly for 1.5 billion upfront and another potential 1
- 38:37billion in milestone payments. Because the data that they
- 38:42showed against this type of breast cancer was so promising
- 38:45that, that Lily stepped up and, and, and, and bought the, the
- 38:49assets for a significant amount of money.
- 38:51And there's also milestone payments involved, which I
- 38:53mentioned earlier. So when we sell a company to,
- 38:56let's say, let's say we develop a, a pill for, you know, let's
- 38:59say in this case, or, or a therapeutic for, for cancer or
- 39:02something, and we sell it to, you know, Anthony Therapeutics,
- 39:06right? You will give us a many times
- 39:07there's a cash upfront payment, which could be significant.
- 39:10There's also milestone payments, meaning that as long as the
- 39:12drug, if it gets, if it gets, you know, passes phase three
- 39:15trials, we get another milestone.
- 39:17If it gets approved by the FDA, we get another milestone
- 39:19payment. So there's milestone payments
- 39:20down down the road as drugs hit certain sales targets or certain
- 39:24regulatory approvals. Let's shift gears just a little
- 39:29bit. I want to hear about how no, I
- 39:32want to come back to this because here's The thing is you
- 39:35guys are developing so many really cool technologies, right?
- 39:39And these things come out and then you've got this called
- 39:43doctors all over the the country, all over the world who
- 39:46are busy, you know, up to their elbows and their day-to-day
- 39:49practice. And they don't know about, for
- 39:52example, this new breast cancer treatment that, you know, is
- 39:55very effective against certain very difficult to treat types of
- 39:59breast cancer. You know, call it small town
- 40:03Ohio, you know, you know, farm country Iowa, where no
- 40:08disrespect to the doctor, but just hasn't hit his radar yet or
- 40:12her radar yet. Like how do you sort of bridge
- 40:14that gap? How do you?
- 40:16And this probably is less your role, right, and more the role
- 40:19of like, whoever's kind of acquiring, you know, what it is
- 40:22that you guys have helped to develop.
- 40:23But it's just something I've always wondered about.
- 40:26Like, how do you sort of think about bridging that gap to
- 40:29here's the latest breakthrough and, you know, how do we
- 40:32actually tell the world about it?
- 40:34Yeah, I mean, a lot of a lot of times the, you know, the data
- 40:36for like companies, especially on the, on the, you know, some
- 40:39of the trial data is published, right?
- 40:41They're published in, you know, in the Journal of American
- 40:43Medical Association or, or, or New England Journal of Medicine,
- 40:46things like that, right. There's a lot of, you know, as,
- 40:48as things, as, as therapies are developed, there's a lot of the
- 40:52science and the and the clinicals are published.
- 40:54There's also a lot. And so there's a lot of you
- 40:56know, and all doctors mostly will be, you know, if they read
- 40:58these journals and and we'll have a sense of what for
- 41:00certain, you know, if they're a cardiologist or, and they're
- 41:03looking at maybe, you know, kind of diseases that, you know,
- 41:06drugs that lower, let's say cholesterol or things like that,
- 41:08or they're, you know, an oncologist, you know, certain
- 41:11types of oncology. They're aware of that.
- 41:13Some of the drugs that are entering trials, in many cases
- 41:16they may in for the leading, you know, kind of academic medical
- 41:19centers, you know, they may be participating in the trials
- 41:21themselves, you know, their patients.
- 41:23But there are a lot of very kind of specialized conferences where
- 41:28a lot of the private companies and even the large farmer will
- 41:30present results for, you know, phase one, phase two, phase
- 41:33three studies for certain types of indications.
- 41:35So within the community, they're, they're you when things
- 41:37are working or there's positive results or you know, kind of
- 41:41landmark studies that are being done, there's quite a bit of, of
- 41:45awareness. Ultimately when a drug is
- 41:49approved and the labeling in the FDA is, is has signed off on
- 41:53everything. And that really at that point is
- 41:55really, like I said, ultimately it's usually the pharma company
- 41:57or it could be the, if the company's gone public and
- 42:00they're publicly traded, the stand alone company themselves
- 42:03to make sure that they can properly market and educate the
- 42:06end consumer, you know, the, the, the primary care physicians
- 42:09or the, OR the, the patient communities in many cases about
- 42:13these new therapies. Yeah.
- 42:16And that bless us, right? Because we're not, we're not,
- 42:17we're not in the business of kind of marketing
- 42:19commercialized. We're just a small kind of
- 42:20venture capital. Yeah, we're, we're, we're there
- 42:22to get the science up and running and get the, and get
- 42:25the, the drug through the clinical trial process
- 42:28successfully. And then typically there's, you
- 42:31know, the, the, whether the company goes public and takes
- 42:33the, the commercialization on their own or they're purchased
- 42:36by like a Merck or Lilly or, or Sanofi or somebody that will
- 42:40then bring it into house, finish the phase three trials,
- 42:42interface with the regulator and, and, and have the
- 42:44commercial half behind it. You know, we talked earlier,
- 42:48Sean, about how the fact that you're working at a company that
- 42:53the, the whole goal is to do good, right, and to improve the
- 42:56quality and the length of people's lives, help them
- 43:01through their medical challenges.
- 43:03But not too long ago in your own life, there was a big challenge
- 43:08that arose for you personally that, you know, kind of bled
- 43:12over into the professional space.
- 43:14I'd like to explore that. I'd like to hear more about that
- 43:16and how you got through that and what it meant for you.
- 43:19Yeah, sure, sure. I mean, I was in San Francisco
- 43:23and working for a company called Farallon Capital Management,
- 43:27which does, you know, kind of a large multi strategy hedge fund
- 43:30will also some private asset strategies.
- 43:32Very well respected has been around for a very long time.
- 43:35One of the, I would say one of the blue chip firms in in our
- 43:37industry and was in position to take a senior leadership role at
- 43:42the firm. Assuming that, you know, I I was
- 43:44able to, you know, execute and, and and and do well, etcetera.
- 43:48And my wife was diagnosed with breast cancer and that was in
- 43:53the beginning of 20, kind of beginning mid 2015.
- 43:59And you know, I had two young children at the time who were
- 44:05in, and one was in elementary school, 1 was in middle school.
- 44:08You know, Farallon is a phenomenal firm, but this
- 44:10industry is, is not for the faint of heart.
- 44:12You, you have to kind of be all in.
- 44:14That's one of the reasons I like, you know, venture capital,
- 44:16hedge funds, you know, private equity, those types of, of, of
- 44:19businesses because it really is kind of the sharp end of the
- 44:22spear, so to speak, in, in asset management.
- 44:24And you need to be kind of all in 100%.
- 44:27You can't be half and half. And so I was trying to do well
- 44:31at Fairlawn, but also support my wife and, and, and, and kids
- 44:34and, and I was not doing particularly well at each, you
- 44:40know, I, I, I thought I could, but I was dropping the ball, you
- 44:44know, in, in both places. And I realized that, you know,
- 44:49it's, you only go around, you know, maybe once, depending on
- 44:53your religious beliefs, maybe you're being incarnated.
- 44:55But, you know, in this lifetime, you really have, have one kind
- 44:58of ride around the merry go round and, and family was, was,
- 45:02is, is, was the most important. So I, I, I left Fairlawn and
- 45:06took an entire year off to help my wife recover, support the
- 45:10kids. I did a lot of nonprofit work
- 45:12and kind of got back into the, the real world, so to speak,
- 45:15which was, I think, you know, very, very grounding 'cause we
- 45:17kind of lose track of ourselves. And in this, the, the world of
- 45:20war and venture hedge funds, what have you.
- 45:23And, you know, I talk to people about it and they say, hey,
- 45:27that's, you know, that's an admirable thing to do, you know,
- 45:30and yes, but you know, I should have done it earlier.
- 45:35I, I, I like everyone else. I thought I could do it all.
- 45:38And then I just hit a brick wall and it became painful, painfully
- 45:41obvious. That's something I had to give.
- 45:43And that thing was certainly not my family.
- 45:45So I took a full year off in 2016, did a lot of, like I said,
- 45:50you know, tutoring and, and, and educational work, which I've
- 45:53always been a, a, you know, kind of a fan of.
- 45:56And then when I decided I wanted to go back to work, I was
- 45:59fortunate that again, the citizenship element, a lot of
- 46:01firms, you know, reached out to me and, and, you know, for
- 46:04opportunities. And did I want to go back to
- 46:08kind of a complicated high headache, high friction type of
- 46:11job in these large firms? Or did I want to do something
- 46:14more entrepreneurial? And that's when I decided to
- 46:17join Yeehung, which was a very small firm at the time.
- 46:19And I said, if I want to put to, you know, put to work everything
- 46:22I've learned and be solely responsible for a lot of the
- 46:25business decisions, this is the time to do it.
- 46:27And I was fortunate that a lot of my former investors and
- 46:29people I know were very receptive to what we were doing
- 46:32again, because of the citizenship angle that I had in
- 46:34the past. And and so, you know, it was, it
- 46:38was, it was stressful 'cause I, you know, you don't know if
- 46:40you're gonna go back to work or if people are wanna hire you
- 46:44after, you know, you've been out for a year and, you know, and
- 46:47you sit around and say, wow, you know, am I ever gonna be able to
- 46:50do what I love or am I gonna find the right job?
- 46:52And you know, why did I leave? But you know why you leave?
- 46:55You had to and so all those things kind of run through, run
- 46:59through your head. And although it did turn out
- 47:02well, certainly, you know, it was, it was a, it was a learning
- 47:06experience and, and you know, it just kind of just forces you
- 47:09again to pay attention to what really, really matters.
- 47:11And we all kind of give lip service to that.
- 47:13But until you're really in that situation, it it, it, it just
- 47:17becomes much more meaningful. So as you were heading into
- 47:21this, you find out that your wife has breast cancer.
- 47:25From the diagnosis, from what they could tell, what was the
- 47:30general prognosis? I mean, there's no guarantees,
- 47:33right? It could look pretty treatable
- 47:34and then turns out it's not or or vice versa.
- 47:37But what what was sort of the feeling?
- 47:39What was the sense in that moment?
- 47:41We had a, we had a, just because of some, you know, kind of
- 47:47biological and kind of genetic history my wife had, she was
- 47:49always going in to, to, to, to, to, to get tested.
- 47:53And, and so when we were living in New York City, when I was
- 47:57working for York, when we decided we needed, we thought
- 48:00maybe having our kids in California instead of Manhattan
- 48:02would be a a bit better for them.
- 48:05When I joined Fairlawn and we were fortunate to go into San
- 48:07Francisco, that UCSF did one additional test on my wife that
- 48:12actually caught the cancer relatively early.
- 48:16So we knew there's always kind of a risk that this would
- 48:18happen. It just kind of, you know, and,
- 48:20and then it in fact did. And had she been diagnosed with
- 48:27this type of cancer 15 years ago or even 10 years ago, the
- 48:32outcome may not have been good, but she was.
- 48:34There's a drug on the market called Herceptin, which was
- 48:36developed by Genentech that was very, very effective against her
- 48:41type of cancer. So we knew that the prognosis
- 48:44was, was good, But, but the road, you know, the road is, is
- 48:50a challenge you want with, there's no, you know, there's
- 48:52just varying degrees of difficult when you deal with
- 48:53cancer. So the chemotherapy and all of
- 48:55those types of things, you know, the course of treatment and the
- 48:59radiation, the surgery, you know, it's, it's really a, a, a,
- 49:01a bit of a, a, a long road and a challenging road.
- 49:04And certainly I, I give all due credit to my wife, who is much
- 49:07more mentally tough than, than, than I was and, and, and held up
- 49:11much better than I did during that whole time.
- 49:14But but again, as, as you know, when I was interviewing at
- 49:17Omega, you know, I met one of our executive partners was one
- 49:21of the was at Genentech at the time they developed perceptive,
- 49:24you know, which saved my wife's life, you know, so, you know,
- 49:27it, it being at Omega kind of brought things back full circle.
- 49:30But, you know, we were very fortunate that we were
- 49:33conservative with our finances and we didn't necessarily, you
- 49:36know, I didn't have to have to work for a certain period of
- 49:38time. So I had the luxury of being
- 49:40able to take it, take time off. A lot of people don't, you know,
- 49:43a lot of people have dealing with family illnesses, whether
- 49:46it's, you know, it's, it's, you know, with the children or
- 49:48spouses or, or parents, and they don't have a luxury of, of
- 49:51taking the time that I did it. So we were very, very fortunate
- 49:55in that respect. But it it definitely, like I
- 49:57said, it just brought a lot of things into, into very sharp
- 49:59focus that I, you know, I had always acknowledged.
- 50:03But you know, it becomes much more real in in the moment.
- 50:05Was there was there any hesitation making that move,
- 50:07stepping away from work for a year?
- 50:11Initially, I, I, I fought it because I, I, it was pretty
- 50:14clear that I needed to step away and I just was stubborn.
- 50:17You know, I thought I could, I thought I could, you know,
- 50:19handle everything and, and, and be Superman and all that stuff.
- 50:22But, you know, look, we're all human.
- 50:25We all have, we all have our, we all have our, we all have our,
- 50:27our, our breaking points. And, and, and I certainly said
- 50:30it was, you know, kind of hit mine and it became pretty
- 50:32obvious that, that I needed to leave.
- 50:34I was a little concerned, you know, when I left.
- 50:36It's like, would people Remember Me?
- 50:38Would I be able to, when I decided if I wanted to go back
- 50:40in the industry, would I be able to get a job or, you know, would
- 50:43I, you know, what, what, what does that look like?
- 50:45And, you know, those were, those are things that you think about,
- 50:49you know, during that time. But like I said, it did work out
- 50:51well, fortunately. But you know, it was it, it, it,
- 50:55it, it is, you know, it, it's, it's an uncertain time, right?
- 50:58And you know, for many of us, our identity is our job in many
- 51:02cases, especially in this industry.
- 51:04And so I, I think I've been a little fortunate that, you know,
- 51:07my job has always been what I do.
- 51:09It's not who I am and so, but Even so it was, it was hard kind
- 51:13of leaving a very prestigious firm in a high profile role to
- 51:16just kind of hang out. And you know, I'm glad that you
- 51:20said it exactly the way that you said it because for so many high
- 51:23performers, entrepreneurs, executives, etcetera and and I
- 51:28and I am guilty of this. I'm raising my hand myself.
- 51:31I very much identify who I am with what I do right.
- 51:34And in those times where I've changed what it was I was doing
- 51:38or I had exited something and didn't know what the next thing
- 51:42was. It's very unsettling.
- 51:45It's very confusing, disturbing. Like where do I sort of fit in?
- 51:50Like I, I was anchored to who I was over here in this job, in
- 51:54this role, in this company. And now that's gone and it and
- 51:58it does feel like part of the your identity has dissolved.
- 52:01Sure, no, I, I, I 100%. And because you know, some of us
- 52:06when you're, when you're, when you throw so much of yourself
- 52:09into your professional life, which in many cases you kind of
- 52:11have to do. And, and especially in the
- 52:12industries that that, that you mentioned and, and the one that
- 52:15I'm in, it's, you know, you can't be 50% there, 80% there.
- 52:18You have to be kind of 110% there all the time.
- 52:21And stepping back from that, it's like, OK, so now who am I
- 52:24exactly? And you know, what is, what is
- 52:26my identity? And, and like I said, I've
- 52:28always been fortunate that I've always kind of divorced a little
- 52:31bit who I am versus what I do. But it was still a challenge,
- 52:34you know, because they don't have an, an identity per say.
- 52:36And, and I give full credit to my wife, who, you know, turned
- 52:40me toward, you know, doing much more volunteer work, which I
- 52:44plan to do. But she kind of, you know, kind
- 52:46of directed me there. I've always been interested in
- 52:47education and tutoring and things like that.
- 52:49And so I was able to kind of channel that to be able to give
- 52:53some back to people. As I say, in the in the real
- 52:55economy, we, you know, I have this, you know, I live in a fake
- 52:59economy of like hedge funds and private equity and, and venture
- 53:02capital and, and, you know, start-ups, whatever.
- 53:05That's kind of the, the fake economy, the real economy is
- 53:07what most people go through on a day-to-day basis.
- 53:09And you know, in many cases, you know, we kind of lose a touch of
- 53:13that a little bit. And so kind of being pulled back
- 53:18into that in terms of kind of what is really kind of going on
- 53:21outside of the world that you're in and you realize you are in a
- 53:24bit of a bubble. And so and and so it, it does
- 53:28force, you know, some some some grounding on you if you don't
- 53:31have it already. Sean, what's your superpower?
- 53:37You know, I dread that question because, you know, I, I, I don't
- 53:41know if I have an answer. I think it and as, as I, as I
- 53:44think about it, I, I think what has enabled me to excel in the,
- 53:50in the rules that I have had and is that I am much more of a
- 53:57multi disciplinary thinker, meaning that I am very, very
- 54:03broadly curious. And then I'm able to take kind
- 54:06of what are very kind of complicated, like I said,
- 54:09situations, strategies, what have you, and synthesize that in
- 54:12a way that also builds upon kind of like business strategy and
- 54:16business imperatives within these organizations that I work.
- 54:18So you take a lot of different elements from whether it's just
- 54:21not of the financial, the narrative, the storytelling, the
- 54:24numbers, you know, the, the, the, the, the, the, the, the
- 54:28sizzle and the steak, so to speak.
- 54:30And to be able to work with people from a long, long, long,
- 54:37long list of, of disciplines that exist within these firms to
- 54:40kind of make the 1 + 1 = 3. And I don't, I can't really
- 54:43distill that into, into one word or phrase, but I think that has
- 54:46served me, you know, served me very well.
- 54:49I don't know if that's a superpower.
- 54:50I have no idea. But that is historically what
- 54:52is, you know, what is distinguished I've been able to
- 54:55do. How about something fun you like
- 54:57to do outside of work, Sean? You know what, I love the
- 55:02outdoors, you know, hiking and, and you know why my, my mother
- 55:07growing up in Northern California was a card carrying
- 55:09member of the Sierra Club. You know, so I like to, I like
- 55:11to, to get out, I like to be outside and in the outdoors.
- 55:13And, and so places like Boston or San Francisco, great for that
- 55:16because you can, you can get out pretty, you know, pretty easily
- 55:19where, as opposed to when he lived in Manhattan, it was, it
- 55:21was much more of a battle to, to, to get out to, to, to where,
- 55:24you know, where, where there's a little bit of nature.
- 55:26But I do love to be out in the outdoors.
- 55:30I do love to, to travel. I travel a lot for work, but
- 55:33it's very sterile. Work travels sterile, right?
- 55:35You're, you're playing car, hotel, meeting restaurant, hotel
- 55:40playing back, right? Whereas I like to do a lot of
- 55:43kind of cultural kind of tourism with my wife and seeing the
- 55:46world, so to speak. And I do, I read a lot.
- 55:50I think that's something that is becoming, you know, ever more
- 55:55scarce just in terms of how society is and kind of how easy
- 55:58it is to, you know, to pretension spans to wander.
- 56:01You know, I find reading is one of the best ways to just
- 56:07distinguish yourself. You know what?
- 56:09Do you like to read? I read, I mean, I mean, there's
- 56:13a lot of stuff that I read for, for work.
- 56:15And one of the great things about our business is like the,
- 56:17the science continues to advance.
- 56:19And so we need to kind of stay on top of things.
- 56:20Even if I'm not a scientist. There's a lot of things that we
- 56:22read kind of a publication standpoint, but there's a lot
- 56:25of, I read a lot of kind of, I try to spread my, my reading,
- 56:30my, my personal reading between something that's more work
- 56:33related or economics or markets or, or kind of related to what I
- 56:36do, something that's maybe fun, kind of like a murder mystery or
- 56:39who knows, right? Or you know, or some like
- 56:42historical fiction. So, but you know, you do need to
- 56:46take the time and, and space away from the day-to-day, put
- 56:49your devices to the side. I do this on Sundays and, and,
- 56:52and read, whether it's the Economist or some of the news
- 56:54publications related to biotech, you know, some of the current
- 56:57investment memos and decks from our portfolio companies.
- 57:00That's all information that you need to have to, to be able to
- 57:03retrieve. And many people will, you know,
- 57:05feed it into ChatGPT. But you can do that for certain
- 57:07things, but it's not the same as being able to retrieve it on
- 57:10your own. I was going to ask actually, do
- 57:13you? Still read completely read all
- 57:16of these articles, all these decks, etcetera.
- 57:18Or are you feeding a lot of them into AI and asking for summary
- 57:22so that you can ultimately consume and synthesize more
- 57:25data? It depends if it's something.
- 57:29That is very, very lengthy on something that is kind of a
- 57:32little bit of ancillary interest, but not, not super
- 57:35important in many cases. I, I can get an AI summary and
- 57:38then decide if it's something that I really want to delve
- 57:40into, right? I don't, I, I use it as, as, as
- 57:43a, you know, as, you know, some of the, the AI tools as a source
- 57:50of, you know, kind of support, but not necessarily
- 57:52illumination. And what I mean is that it'll,
- 57:55it'll help me direct where I want to spend more time as
- 57:58opposed to using it as a shortcut to take away time.
- 58:01If that's, if that makes, if that makes sense.
- 58:03I'm going to use it as a shortcut to learning.
- 58:05I use, I use it as a shortcut to what I want to learn more about.
- 58:08Gotcha, get some summaries. On things that you're not sure
- 58:12about, if it's worth investing the extra time.
- 58:14And then from the summary, you can determine, oh, these two
- 58:18things out of these five, this is what I want to dive deeper
- 58:21into and I'm going to go and consume it the old fashioned
- 58:23way. Exactly.
- 58:24And and just, I'm just old fashioned I guess in.
- 58:26Terms of I, I just find I retain things if I'm, if I'm actually
- 58:29reading it on my own. And that's a a muscle that you
- 58:31need to, especially today, you need to kind of work really,
- 58:34really hard to maintain because there's so many things that are
- 58:37just, you know, competing for your attention.
- 58:38There's a lot of very surface, how to say kind of surface
- 58:43knowledge out there. But again, in in our business
- 58:46and especially, you know, when you're more of a specialist and
- 58:49you're dealing with more comic complex kind of complicated
- 58:52concepts, you you need to, to, to, to dive in on your own.
- 58:56Yeah, for sure, Sean. I've just got one more question
- 58:59for you today, but before I ask it, I want to do 3 quick things.
- 59:03First of all, if you want to get in touch with Sean Kaminsky
- 59:05today, he's given us his e-mail address to hand out to you.
- 59:08It is SC at omegafunds.com. SC at omegafunds.com and we'll
- 59:14have that in the show notes too. Also, as a reminder, if you want
- 59:18to get more employees access to benefits that won't hurt them
- 59:21financially and carries a financial upside for the
- 59:23company, reach out to us at Add Back benefits.com.
- 59:27Finally, if you will take just a moment to leave us a comment or
- 59:30review on your favorite podcast app, you will hold a special
- 59:33place in my heart forever. Thank you so much.
- 59:36So last question for you, Shawna, you're from now you and
- 59:38I reconnect and you're celebrating something really
- 59:41big. What's that big thing you hope
- 59:43to be celebrating one year from today?
- 59:47That's a good question, I think. You know, from the, the thing we
- 59:51recently celebrated as as a family was my wife's kind of,
- 59:55you know, 10 year marker for, you know, breast cancer
- 59:57survival, which is which once you've on it, the, the, the
- 1:00:01past, the 10 year window for treatment, you know, your odds
- 1:00:04of being of a becoming, you know, being in remission are,
- 1:00:07are, are much, much, much higher.
- 1:00:10And so that was very, that was the anniversary that we were
- 1:00:12looking for, but. You know, from, as I think about
- 1:00:16kind of over the over the next year and it's probably like a
- 1:00:18maybe a year and a half from now.
- 1:00:19What I really want to be able to do is, is you know from our,
- 1:00:24where we're raising Fund 9 on the professional side.
- 1:00:27And you know, if we can slightly increase the size from fund 8 if
- 1:00:31we want to and make it a much more seamless, less laborious
- 1:00:36process, cause fundraising is, is a grind.
- 1:00:40You know, I will, I would be thrilled to have that happen,
- 1:00:42Which means that it's really just the residual of all the
- 1:00:45restructuring and process engineering that we've done in
- 1:00:47the past years will have been effective.
- 1:00:51Say more about that some of this process.
- 1:00:53Engineering that you guys have done the restructuring to make
- 1:00:56things more efficient on the fundraising, yeah, I mean it's a
- 1:00:58lot of it is, you know, many people think.
- 1:01:00Fundraising is just kind of running around helter skelter
- 1:01:03and meeting with investors that might be interested in pitching
- 1:01:05them on your fund, etcetera. And, And, and in some ways that
- 1:01:09that is true. But, but really, you know, I
- 1:01:13come not from originally being, you know, kind of a, an asset
- 1:01:16raiser or, or, or or client person.
- 1:01:18I, I come from like the product and investment side early in my
- 1:01:20career. And so I'm very process
- 1:01:22oriented. And so, you know, you really
- 1:01:24can't manage what you can't measure.
- 1:01:26And so that means, you know, optimizing, you know, the CRM
- 1:01:30experience, a lot of CRMS out there that are not so great, but
- 1:01:33being able to make sure you're pushing the limits of what they
- 1:01:35can do for you, that you're automating things as much as
- 1:01:37possible, that you're taking the, the human element out in
- 1:01:40many cases, because that just invites, you know, kind of user
- 1:01:43error in many cases, making things kind of scalable, you
- 1:01:47know, measurable. And from a, you know, kind of
- 1:01:50marketplace or strategic standpoint, having a real
- 1:01:53strategic plan in terms of what you're going to do, how you're
- 1:01:56going to do it, how you're going to measure yourself against
- 1:01:58that. And that goes with maybe certain
- 1:02:00client segments, whether it's like, say, the hospitals or, or
- 1:02:04medical foundations or pension funds or sovereign wealth funds
- 1:02:07or family offices. Now I'm fortunate that I'm, I
- 1:02:09work with all those types of clients and kind of conversant
- 1:02:11in their own specific dialect, I guess if you will, and then
- 1:02:15building the, the team and process around the firm that can
- 1:02:18make that work. And again, it's the 1 + 1 = 3.
- 1:02:21You want to make sure that you put the firm in the best
- 1:02:23position to succeed whenever you are, whenever you're going out
- 1:02:26to, to meet an investor. And a lot of that has to happen
- 1:02:29behind the scenes prior to even getting to the meeting.
- 1:02:34Sean Kaminsky. From Omega Fund Management, I
- 1:02:37want to be the first to thank you for sharing both your time
- 1:02:39and your story with us today. I really appreciate it.
- 1:02:43No, thank you very much. It's, it's been a pleasure and
- 1:02:45I, I hope. I was able to to provide some
- 1:02:48interesting commentary on what we do, but I guess you know, the
- 1:02:51audience will decide that I've already decided the judgement is
- 1:02:54in. You did well.
- 1:02:56Thank you, Sean. That's very kind of you.
- 1:02:57Thank you, folks. That's a wrap on another.
- 1:03:00Episode of the Inspired Stories. Podcast, thanks for learning
- 1:03:02with us today.