1277-SLC Transporters in Cancer Metabolism
The Solute Carrier (SLC) transporter family, a vast group of over 450 proteins, serves as the primary gateway for moving essential nutrients like glucose, amino acids, and lipids across cell membranes. While these proteins maintain healthy metabolic balance in normal tissues, they are frequently hijacked by cancer cells to fuel rapid growth and resist medical treatment. Key transporters such as GLUT1, LAT1, and xCT drive metabolic reprogramming, helping tumors survive in harsh environments and evade the immune system. Because of their central role in malignancy, these transporters have become…
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