Latest / Hope & Histamine: The Paediatric Allergy Podcast
Basophil Activation Test (BAT): Accuracy, Interpretation & Clinical Use in Allergy Diagnosis
In this episode, we dive deep into the Basophil Activation Test (BAT) — one of the most advanced tools in modern allergy diagnostics. Join us as we break down how BAT works, when to use it, and what the evidence really says about its accuracy in diagnosing IgE-mediated food allergy, drug allergy, and complex sensitisation patterns.
You’ll learn:
• How BAT compares with skin prick testing and specific IgE
• The clinical value of basophil activation markers such as CD63 and CD203c
• When BAT improves diagnostic confidence and reduces the need for oral food challenges
• Limitations, pitfalls…
The skinny
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