567-HistoSweep for Digital Pathology and Omics

Paper Talk · Feb 28, 2026 · 22m

Researchers have introduced HistoSweep, a computationally efficient and scalable framework designed for high-resolution tissue quality control in digital pathology and spatial omics. The tool addresses a critical gap in the field by moving beyond simple foreground-background separation to generate cellular-resolution masks that exclude artifacts, acellular voids, and noise. By integrating color statistics, texture descriptors, and adaptive thresholding, HistoSweep preserves biologically meaningful microstructures without requiring expensive GPU resources. Experiments across 25 diverse…