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1551-SpaMTP for Spatial Metabolomics&Transcriptomics

The paper introduces SpaMTP, an open-source software framework designed to bridge the gap between spatial metabolomics and transcriptomics. While these two fields offer distinct insights into cellular regulation, researchers previously lacked integrated tools to analyze their data simultaneously. Built upon the familiar Seurat architecture, this new platform offers advanced capabilities for metabolite annotation, joint clustering, and multimodal visualization. By streamlining the processing of mass spectrometry and gene expression data, SpaMTP enables a more comprehensive understanding of…

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