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Interorgan Insights: Pulmonary Vascular Endothelial Cell Dysfunction Associated With the Nonpulsatile Pulmonary Blood Flow in an Ovine Glenn Model
In this podcast, co-first author Jonathan Hyde discusses the recently published article, ‘Pulmonary Vascular Endothelial Dysfunction is Induced by Nonpulsatile Pulmonary Blood Flow in an Ovine Classic Glenn Model’. The study used an in vivo large animal model combined with ex vivo and in vitro studies to investigate pulmonary vascular endothelial cell dysfunction associated with the Glenn procedure. The results suggest that low, non-pulsatile flow associated with Glenn physiology plays a pivotal role in development of endothelial cell dysfunction.
Pulmonary Vascular Endothelial Dysfunction Is…
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