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The Risk of Additional Testing Follow-Up with Ashley Holt. Episode 44.
In this highly personal follow-up episode of "Cracking Cancer," host Dr. Kyle Concannon and patient advocate Ashley Holt navigate the "mental hell" that can arise when advanced medical technology outpaces clinical certainty. Ashley, a Stage I lung cancer survivor, shares the harrowing story of her Signatera blood test (a tumor-informed ctDNA test) turning positive on her one-year diagnosis anniversary.
The episode pulls back the curtain on the months of uncertainty that followed: a clean PET scan and brain MRI, two follow-up blood redraws, and the agonizing wait for results during the holiday…
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