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#28 - How AI Confidence Masks Medical Uncertainty

Can you trust a confident answer, especially when your health is on the line?

This episode explores the uneasy relationship between language fluency and medical truth in the age of large language models (LLMs). New research asks these models to rate their own certainty, but the results reveal a troubling mismatch: high confidence doesn’t always mean high accuracy, and in some cases, the least reliable models sound the most sure.

Drawing on her ER experience, Laura illustrates how real clinical care embraces uncertainty—listening, testing, adjusting. Meanwhile, Vasanth breaks down how LLMs…

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