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Detecting the Undetectable: Dr. Andrew Callen on Spinal CSF Leaks

Spinal CSF leaks are among medicine’s most elusive disorders—often missed, misdiagnosed, or misunderstood. But emerging imaging techniques are changing that narrative.

In this episode of Frame by Frame: Rethink Imaging, host Chris St. John welcomes Dr. Andrew Callen, the pioneering radiologist behind the University of Colorado’s multidisciplinary CSF Leak Program, to discuss how specialized MRI and CT protocols are enabling clinicians to “detect the undetectable.”

Dr. Callen explains how subtle imaging details, like distinguishing fat from fluid through fat-suppressed T2-weighted MRI, can…

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