Latest / Pediatrics Now: Cases Updates and Discussions for the Busy Pediatric Practitioner / How an Infectious Disease Expert Actually Eats Right Now — Plus: Bexar County’s Rabies Hot Zone
Transcript
- 0:03I'm Holly Wehment, and this is Pediatrics Now, cases, updates,
- 0:07and discussions for the busy pediatric practitioner, brought to you by UT Health's
- 0:12Department of Pediatrics.
- 0:15I'm thrilled today because joining me here in the podcast studio back on the show is Dr. Dina Sutter.
- 0:23Dina is the new Division Chief for Allergy, Immunology, and Infectious Disease
- 0:28here at UTHealth San Antonio, and she has more than 20 years of experience in infectious disease.
- 0:34Dina, thank you so much for being back here on Pediatrics Now.
- 0:38Thanks for having me, Holly.
- 0:40This is being called one of the largest cyclospora outbreaks on record,
- 0:44and it's gotten heavy social media attention.
- 0:47How do you help families separate the scale of the national number from their actual local risk?
- 0:54And what is your advice for pediatricians who are getting these questions?
- 0:58Ultimately, we know that Texas has cases.
- 1:02Like all the other parts of the country, they're being underestimated for sure.
- 1:07So I believe that we probably have, you know, there's been different reports,
- 1:12probably over 200 cases, although they're a little bit lagging.
- 1:16So I think there were about 140 that were reported a couple weeks ago.
- 1:20We have had, and this is not patients that I have, these are actually adult
- 1:23patients based on, you know, they just give the age.
- 1:26I don't know anything about the specific cases, but I know that we had one case
- 1:31reported just generally on
- 1:33our lab data last week, and then this week they're reporting nine cases.
- 1:37So without details on where the patient traveled, because potentially they went
- 1:42to another state, we do know that there was lettuce that was part of the recall
- 1:47that was distributed in Texas.
- 1:49So I think overall for parents' questions, I think that looking at what the.
- 1:56Department of Health is reporting,
- 1:59up-to-date numbers, and then getting in the network of finding out what other people are seeing.
- 2:05The reason that we actually can identify this pathogen in the vast majority
- 2:08of cases is because it's part of a PCR panel for gastrointestinal pathogens.
- 2:14If we were just using the old school methods where they had to do special staining
- 2:18on multiple stool samples, we probably wouldn't know about the vast majority of these.
- 2:22But because these panels are so readily available, and because this is in the
- 2:27news, potentially people are testing more.
- 2:30So it's really, really hard to assess how many cases we have here locally versus nationally.
- 2:35I mean, we know that there have been very, very numerous, large numbers of cases
- 2:40in Michigan, Ohio, and I think there's maybe another cluster in North Carolina
- 2:44that's being discussed.
- 2:45So Texas is relatively less affected, and hopefully we won't have a massive
- 2:51number of cases as the product was recalled. But we also know...
- 2:55That this organism takes a while to incubate in the human and actually cause disease.
- 3:02It goes through a very complex life cycle, which is, you know,
- 3:05I don't, I can tell you exactly the states, but basically, you know,
- 3:08invasion and then the organisms, you know, sporulates, you get these life forms
- 3:14that go back into the intestine.
- 3:15So basically, you know, they say you could have symptoms within like three or
- 3:18four days, but generally it's a couple of weeks.
- 3:20So the number of cases in Texas may rise, even with the product being recalled,
- 3:24because there's a delay in presentation of symptoms.
- 3:28So it's really, really, really hard to say.
- 3:31Overall, for families, one of the discussions is like, what should we avoid?
- 3:35And I think we're going to talk about that.
- 3:37The good news is that a lot of kids, I know families really try to get their
- 3:40kids to eat vegetables, but
- 3:42I feel like children, you know, especially young children who are infants and
- 3:46And young children, especially children who are immunocompromised,
- 3:50you know, transplant patients, those patients should not be eating,
- 3:53any of these fresh fruits and vegetables anyway.
- 3:55But young kids can get, you know,
- 3:56diarrhea and get dehydrated faster than adults. It can be more severe.
- 4:00But the good news is, I think, as we were discussing, a lot of times younger
- 4:03kids don't want to eat lettuce, which is maybe a good thing right now.
- 4:08Yeah, it's hard to get kids and teenagers, I know with my three kids,
- 4:12to encourage lettuce. But my son and I were having lunch together yesterday
- 4:17at a restaurant, and then he ordered lettuce wrap.
- 4:21And then when I mentioned, you know, that that's on iceberg lettuce, but it's probably okay.
- 4:25We've only had a handful of cases that we know of here in San Antonio.
- 4:30But then there was nothing I could say to get him to still, you know,
- 4:34have the lettuce or have even get that. So I guess it's not hard to convince
- 4:38people not to eat lettuce. But I mean, what is your advice?
- 4:41Yesterday, it was funny because I went over to my neighbor had extra hamburger
- 4:45patties and she was leaving town. She goes, would you like some?
- 4:48I said, sure, we'll eat hamburgers. And I went over and she had these two boxes
- 4:51of lettuce from, you know, H-E-B, which is where we all get our groceries, you know.
- 4:55And H-E-B has stated that none of their products were part of the recall.
- 4:58I think that there was some distribution of these products to Walmart is what
- 5:02I was told, you know, is what I read and possibly other stores.
- 5:05But it's hard to say, you know, you only have the information you have.
- 5:08So my neighbor handed me these hamburger patties and these two boxes of lettuce that were...
- 5:14Pre-washed, but it wasn't cut up in a salad. And she made a joke about,
- 5:17hey, you can have some diarrhea.
- 5:20And when I went home and I rinsed this lettuce, which my children do not eat
- 5:24the lettuce, but my husband and I do, I actually was a little more careful than usual in rinsing it.
- 5:29Now, I did not eat it. And it was, I don't know if it was iceberg.
- 5:33I don't think it was iceberg anyway.
- 5:34So long story short, you only have the information you have that's being reported
- 5:39in the news. Sometimes the news will have information that's not coming up on
- 5:43the health department's websites.
- 5:45The CDC is supposed to have updated information. That has really lagged.
- 5:49The reporting on a lot of these things has lagged, unfortunately.
- 5:52And so if I was going into a situation where I was going to eat lettuce,
- 5:56I tend to kind of like not follow all the rules exactly. But,
- 6:00you know, again, if you can actually wash your products, not necessarily that
- 6:04it's effective for high-burden cyclospora.
- 6:06Cyclospora, you know, you probably might reduce the number of organisms,
- 6:09but you know that you can't necessarily get all the organism off of there.
- 6:13But, you know, there's this guidance on how to manage your fruits and vegetables,
- 6:17and I can talk more about that.
- 6:18Yes. How much should we be washing our lettuce and produce? And it sounds so
- 6:22scary that it can't be washed off. Is that because the way it's grown? Yeah.
- 6:26I mean, ultimately, with any, some, you know, you should always rinse your produce.
- 6:31So I get produce from the store and it says pre-washed, and I still rinse it.
- 6:34Now, I also do things that I know I shouldn't do. I use a lot of parsley and cilantro.
- 6:39Herbs are really highly implicated in these outbreaks, even more so than lettuce,
- 6:43because if you think about the structure of an herb, when they're grown,
- 6:46there's so many different surfaces.
- 6:48And then one thing that I have been reminding myself to do is you're supposed
- 6:51to take them, you know, I shouldn't admit that I do this.
- 6:55They're in those little bunches that are tied like with a twist tie.
- 6:59And if I'm in a hurry, I'll usually like hold it and rinse it under the faucet
- 7:04and then chop it from the end. but really what you're supposed to do is take
- 7:06it apart, rinse it thoroughly in running water, and then you could like dry
- 7:11it on a paper towel or something.
- 7:12Especially for herbs, it's a problem. So if you, you know, the guidance is like
- 7:16if you get lettuce, you should discard the outside leaves of the head of lettuce,
- 7:20cut any bad parts off, any part that looks like it might be a little brown.
- 7:23I mean, ideally you don't want that.
- 7:25And then rinse all the leaves thoroughly in running water. Now.
- 7:29So cyclospora is, you know, is an organism that tends to adhere.
- 7:32It also is not eradicated by using bleach or chlorine products.
- 7:37There are some chlorine products that along the way in production you could
- 7:41use to try to reduce the burden, but that works better for bacterial pathogens.
- 7:46And cyclospora, it's not as effective.
- 7:48Overall, for food safety, because we have a lot of different outbreaks that
- 7:51are happening all the time, we can get E.
- 7:53Coli contamination, and cyclospora is classically associated with berries,
- 7:58but things like E. coli and salmonella can also be implicated in produce.
- 8:03Usually we think about salmonella with egg, chicken, and some milk products.
- 8:07But overall, if you have something like an apple that you can rinse the surface
- 8:11thoroughly, most organisms are not going to adhere to that.
- 8:14If you have something like an orange or a banana where you can peel the surface,
- 8:17those are generally considered safe.
- 8:18And this is the kind of things I tell people for when they're when they're traveling,
- 8:22you know, travel medicine advice, if they're going to a country where there's
- 8:25a high risk of diarrheal illness from various pathogens, it's always like,
- 8:30you know, you're supposed to peel it or if you can't wash it,
- 8:32it's not smooth, you shouldn't be eating it.
- 8:33So lettuce salad in general is like one of those things where I'm like,
- 8:37if you eat that, that you have a very high risk of getting diarrhea.
- 8:41And we don't think about that being the issue in the United States.
- 8:44But clearly we're having a problem, you know, you have imported products and
- 8:49it's not impossible that a product grown here could have that, you know, to be honest.
- 8:53But a lot of times these products are coming from other countries where maybe
- 8:57there's a little bit less regulation of, you know, in terms of contamination.
- 9:00They're supposed to, you know, there's all these FDA rules, you know,
- 9:03they're supposed to food safety rules. But overall...
- 9:07You get these products, and then sometimes if you get like a mixed box,
- 9:11you know those boxes that you get from the grocery store where there's like
- 9:15a pre-made salad, those are considered super risky even if there is an outbreak.
- 9:20You know, in the U.S., I wouldn't say super risky, but riskier,
- 9:23because if there's products coming from multiple countries, multiple sources
- 9:28and farms, and they get mixed together in some plant.
- 9:32You can have a lot of additional contamination.
- 9:35And so right now, the recommendation is kind of potentially avoid some of those things.
- 9:40The recall, if they don't report something, there's maybe other outbreaks going on.
- 9:45And if you don't know which product to avoid and then the product gets recalled,
- 9:48if you want to be careful, you know, getting your own head of lettuce,
- 9:51rinsing it thoroughly, rinsing your tomatoes thoroughly, rinsing all the products
- 9:54very thoroughly or peeling things.
- 9:57And if you have an immunocompromised person or someone who has a lot of health
- 10:00problems, they probably should just, you know, that could, these are riskier.
- 10:03I'm not saying don't eat them, I'm just saying that they could be riskier foods
- 10:06in the absence of knowing that you shouldn't eat a certain product or a recall.
- 10:10Obviously the other safe thing to do is to be watching for recalls.
- 10:14Because there could be recalled products on a shelf somewhere that haven't been
- 10:17removed, and you definitely don't want those things either.
- 10:21And is it just the prepackaged salads or also, you know, where you can buy salad
- 10:27in a plastic box or bagged salads? Are those riskier than a head of lettuce?
- 10:32Yeah, if there's contamination, they're considered riskier because there are more cut-up surfaces.
- 10:38And like I said, the aggregation of different vegetables that are coming from different sources.
- 10:43So if there's like, you know, one product is contaminated, it could actually
- 10:48be spread, you know, diffusely. And then they always say pre-washed and like, dude, don't do that.
- 10:55Still wash it. I still wash it. Wash it in running water. Don't soak it.
- 10:59Don't soak it. Don't, yeah. Soaking it does not, you really need the running
- 11:03water. Again, that's not super effective for, you know, for cyclospora.
- 11:07If you put it in a colander and then let the water rinse through,
- 11:10is that ideal? Yeah, that's ideal. You just need to agitate it.
- 11:13And like, again, if you have something that you can rub the surface,
- 11:16like, you know, you know, I'm using an apple as an example. There's other things.
- 11:21Then that's a lot more effective. But, you know, really vigorous rubbing the
- 11:24surface of iceberg lettuce is going to tear it up. And so you just kind of have
- 11:27to be realistic that that might not be effective.
- 11:29It. The other thing to think about is with fruits and vegetables,
- 11:33I'll give you another example of something that I should not do and I do.
- 11:36If you get like an onion, for example, or you get, you know,
- 11:39an avocado, you know, or something like that, I'll chop onion and I'm in a hurry
- 11:43and I don't cut it and then pre-peel it.
- 11:45And there is like, the onion was grown in soil.
- 11:49And so when you cut something and you drag the surface through,
- 11:52whether it's a pineapple or, you know, some watermelon or something like that,
- 11:57or even an avocado, it's safer to wash the surface of the thing and then cut it and then,
- 12:03remove the inside and not drag that surface, you know, like the surface of the.
- 12:09Onion skin or whatever, because that bacteria can be dragged through the food product.
- 12:13So peel the skin off and wash it. Ideally. Now, most of these are recommendations
- 12:17for like if you're in another country and you're preparing your own food there,
- 12:21you know, and we don't think about those things being an issue here.
- 12:24But every time we have an outbreak and a recall, then it's like,
- 12:28well, what could you have done in case you got exposed?
- 12:31You know, could you have mitigated some of the risk? Mm-hmm.
- 12:33At the restaurant, the waiter, he mentioned that he's had so much lettuce leftover,
- 12:39so he feeds it to his tortoise.
- 12:42But then I was thinking, like, wait, do you wash your hands before and after
- 12:45touching the tortoise? That could be another thing. The tortoise,
- 12:47yeah. Like salmonella risk. Salmonella risk in a tortoise, yeah.
- 12:51I mean, you know— It's interesting. The tortoise is being fed well because no one's— Yeah.
- 12:54And a lot of food preparation issue can be not contamination from a plant,
- 12:59but can be in a restaurant where, you know, people are shedding salmonella.
- 13:03For example, and then that can contaminate the food.
- 13:06Things like E. coli, there's different types of E. coli and certain E. colis we have here.
- 13:12We call them shiga toxin-producing E. colis. People are probably familiar with the O157H7.
- 13:17We definitely have ongoing outbreaks or recent outbreaks with that and other
- 13:20shiga toxin-producing E. colis.
- 13:22And that often comes from animal products. If something happens where you have
- 13:27an animal product that's cut up and mixed into something else.
- 13:30You know, you can get contamination.
- 13:34It's not just meat and eggs, though, or meat and dairy.
- 13:39You can also get that into fruit and vegetables, too. And I always tell people,
- 13:43like, if you don't want to get even something like norovirus,
- 13:45which can be easily spread from food workers, for example,
- 13:48the highest risk foods are, like, if you go somewhere and you go get,
- 13:51like, fresh salsa that's been sitting in a thing, then you have,
- 13:55like, multiple factors.
- 13:56You've got you've got vegetables from all over, you've got maybe whatever food
- 13:58handler issues there could possibly be, and then it's been sitting around.
- 14:02So I was told one time when I was in training that.
- 14:05Going to eat salsa, like at a salsa bar, you know, which we have lots of here,
- 14:09eating like pico de gallo is like the highest risk thing you could possibly
- 14:11do. Really? I didn't know I needed to worry about salsa. Yeah.
- 14:15I mean, especially if it's fresh. I mean, do I go and eat the pico de gallo? Yes, I do.
- 14:20But, you know, if you have somebody who's immunocompromised,
- 14:22they should have been giving you, depending on the level of immunocompromised,
- 14:26for example, you know, you should be getting advice.
- 14:29Pediatricians should be giving, and especially if you have somebody who's like
- 14:33on chemotherapy or has had a transplant, they're giving advice not to eat fresh
- 14:37fruits and vegetables, you know, cook these things.
- 14:40You know, cooking iceberg lettuce is not something I'm going to do,
- 14:42but, you know, that's the way to destroy these pathogens is thorough cooking.
- 14:46Same with, obviously, meat.
- 14:48And then milk products, we have outbreaks going on with milk and salmonella
- 14:53in particular, but some of these other things can contaminate milk.
- 14:56And I have, I run into a lot of patients who drink raw milk
- 14:59and this is that's one thing that if they say that I kind of like that's a very
- 15:03risky thing to do and people feel like there's health benefits but like really from the
- 15:07the farm yeah it's got to be it's more natural so it must be better is that
- 15:11the idea pasture you know pasteurizing it kills you know good things or whatever
- 15:15but like I would never drink raw milk like that's I'm I'm kind of a little bit,
- 15:20fault not following my own recommendations but I would you know if you have
- 15:22patients who are drinking raw milk things like listeria salmonella E.
- 15:26Coli, you can have contamination, and people do get sick from that.
- 15:29And there's no health benefit to the raw milk versus pasteurized?
- 15:34If there is, you know, it's questionable data.
- 15:38I think the risk benefit is really not, you know, you really should probably
- 15:41eat, you know, pasteurized cheeses, pasteurized milk, and even some that are
- 15:45supposed to be pasteurized who have had outbreaks with soft cheeses that were
- 15:49produced in the U.S., you know, after they were produced in a U.S.
- 15:52Plant, maybe have come, dairy has come from another country,
- 15:55and there were listeria outbreaks in the last few months. So there's a lot of
- 15:59different things, and this cyclospora thing has really hit the news because of the number of cases.
- 16:05The, there are over, you know, the CDC is basically saying, based on,
- 16:09you know, maybe not their site
- 16:11at the time, that there are at least 20,000 cases, not all lab confirmed.
- 16:15But I also, you know, I'm sure there are a lot of cases out there that the reporting
- 16:20is lagging and we really don't know about them.
- 16:22We're doing this interview in early August. So, and that's where the numbers
- 16:26are right now and nine in the San Antonio area. Yeah.
- 16:30And I think the thing is, like I said, you have something in the news.
- 16:33So people with diarrhea, because you can get explosive diarrhea from norovirus,
- 16:37you know, may present a little different.
- 16:39But if you see a severe diarrheal illness in the, you know, in the past,
- 16:43we didn't have these tests where you could look and sometimes you'll see a kid who's got E.
- 16:46Coli, salmonella, campylobacter, you know, norovirus, and they might have multiple
- 16:52different organisms depending on where they came from and what they ate,
- 16:55especially international travelers.
- 16:57So we wouldn't have known about a lot of these things if these tests weren't
- 17:00readily available. And a lot of places, smaller hospitals, clinics,
- 17:04like they aren't readily available, or they might be able to order them but send them out.
- 17:09So if you're in a large place like this that actually does the testing on site,
- 17:13you're going to get that data a lot faster.
- 17:15But there may be, you know, for every patient who they've identified,
- 17:18there may be patients who have very mild cases, who are asymptomatic,
- 17:23or people who are sick and just never got tested.
- 17:26The good thing about this is Is this not spread directly from human to human?
- 17:29Like salmonella can be? Yeah, salmonella can be. And also it doesn't have an animal reservoir.
- 17:34So this is just this particular species of cyclospora is only in humans.
- 17:40And you can shed it in your stool. I mean, presumably these things did come
- 17:45from a human because only humans get them.
- 17:47But you have to have like fecal contamination of water. This is probably what
- 17:50happened in this plant, this place in Mexico, right?
- 17:55The argument is not that people are actually defecating in the field.
- 17:58They probably have something equivalent to a latrine. They may have porta-potties,
- 18:04maybe the management of that contaminated water products that went on the lettuce.
- 18:14So you have to have these organisms have to be in the environment for some period
- 18:18of time, several days to a couple weeks, before they become infected.
- 18:22So if somebody is shedding in their home with diarrhea, you're not going to
- 18:27transmit it to another person like norovirus, which is very,
- 18:29very, very likely to be transmitted.
- 18:32It's really the food product is a problem here. Dina, how does pediatric cyclosporiasis
- 18:38typically present and what should prompt a clinician to specifically test for
- 18:42it since routine stool panels miss it?
- 18:45It depends on what kind of assay you have. Most people will do an assay that
- 18:50includes parasites, including Giardia, Cryptosporidium, and Cyclospora.
- 18:55If you're going to send that test... Now, if people are using different assays,
- 18:58like the pediatricians in the East community, and these are,
- 19:00you know, obviously you're not going to have on-site testing.
- 19:03You're going to order it and send it out.
- 19:04So if people are using different assays that only can include bacteria and viruses,
- 19:09then you're going to miss it in those cases. But the panel that's most commonly used is,
- 19:14today, and they've modified that panel over time, will detect it.
- 19:18Send it out. And your clinic is in University Hospital. Yeah.
- 19:21So, I mean, I haven't been sending this test, but if I have a child,
- 19:24like if we have a patient admitted to the hospital, or if I had a patient who
- 19:28I had a concern about, I'll order the test and it'll get done locally.
- 19:31But the symptoms really are, if you have a kid who's got profuse, watery diarrhea.
- 19:37Or if you have a kid who has other kinds of presentation, like fever and diarrhea,
- 19:41you know, bloody diarrhea, which does not really occur with this,
- 19:43you're probably going to send that panel if it's significant enough for all
- 19:47the patients who come in with diarrhea.
- 19:48Now, if the pediatricians in the community are not doing this because it's a
- 19:51send out, or honestly, because it's much easier to obtain a stool sample from
- 19:57a child who's admitted to the hospital.
- 19:59So if you tell a parent, like, unless this kid is stooling right there and you
- 20:02can collect it in a diaper or something, or the kid can do it on command because
- 20:05there's so much diarrhea, you send them home and they may not,
- 20:08you know, frequently people don't, come back with the stool sample.
- 20:12So I think that your patient would really have to have significant symptoms.
- 20:16It's not recommended that we do it like to survey and for surveillance type
- 20:21of testing, but, you know, it's worth sending the panel if your patient has,
- 20:26significant diarrhea because you need to know whether you should give antibiotics or not.
- 20:29And in this case, there is an antibiotic that can be used as opposed to something
- 20:33like the shiga toxin producing E. coli where you should not give antibiotics.
- 20:37Or in general, salmonella, depending on the patient's age, we generally don't
- 20:40give antibiotics if it's just diarrhea.
- 20:42So do you want to mention which antibiotic that is?
- 20:45Oh, yeah. So for this, you would get Bactrim, trimethoprim sulfamethoxazole,
- 20:50which is generally not used for other things, other kinds of diarrhea.
- 20:54Like in the old days, we might use it for Shigella, which also can be treated
- 20:58with antibiotics. But there's more resistance among Shigella.
- 21:01This is really the most effective.
- 21:03Other medications, quinolones and nitazoxinide, can be used.
- 21:07They're just not as effective as the trimethoprim sulfa.
- 21:10And the exception with salmonella is if it's a baby, four months or less.
- 21:15It could be a medical emergency.
- 21:16It depends on the age. Yeah, we've kind of bumped that age up.
- 21:19So, you know, we historically would say under three months you should treat them.
- 21:23Typically, if they have bacteria in the bloodstream, they're bacteremic.
- 21:26They have invasive disease, intra-abdominal stuff.
- 21:28We always treat everybody no matter what their age. Because it could be quickly
- 21:32life or death situation. Yeah, and then if the kid's sick, sometimes we'll treat
- 21:37kids even older than the three to four month range. It depends on how they present.
- 21:40And there's been a couple of serious cases recently involving babies.
- 21:45Yeah, we've had a lot of salmonella cases.
- 21:47It comes in waves, and sometimes you really try to pin down where the patient
- 21:51was or what the exposure was.
- 21:53In town, not at my hospital, but recently we've had a baby.
- 21:57We've had several babies with salmonella who do not eat food.
- 21:59They just take formula. And then there's always a concern is,
- 22:02you know, their salmonella contamination of formula is possible.
- 22:06And then it's really tough because you think, well, it could be in the environment,
- 22:11you know, if a parent or a sibling is shedding or they cross-contaminate formula
- 22:16preparation when they're cooking chicken or something, that could be the source.
- 22:19But these things sometimes need to be investigated and we try to hand it over
- 22:23to the health department.
- 22:24And in our Pediatrics Now news feed, we have an episode with Dr.
- 22:28J.B. Canty on salmonella and medical emergency in babies with more information on that.
- 22:35So, Dina, is there a rational clinical basis for elevated caution with iceberg
- 22:39lettuce specifically, or is it more about supply chain traceability than the vegetable itself?
- 22:46Yeah, because the prior outbreaks have been things like basil and cilantro.
- 22:51So it's not something specific to iceberg lettuce. It just happened to be the
- 22:54thing. You know, leafy greens are the highest risk, as I've discussed.
- 22:58You know, those are the things that are higher risk than other things,
- 23:01even things that you can't peel.
- 23:03If it's like, and the leafy greens and berries, specifically raspberries,
- 23:08I guess blackberries could be implicated.
- 23:09Anything that's like a bumpy surface where there's a higher risk of bacteria
- 23:13getting there or parasites in this case, it's not iceberg lettuce intrinsically.
- 23:19It's just what happened with the supply chain.
- 23:22Now they're doing investigations of different outbreaks and there may be other
- 23:26outbreaks that are being caused by other, because every summer we do have cases,
- 23:30you know, there are usually like, you know, three or 4,000 cases in the U.S.,
- 23:33and they may be coming from other sources, so they have to do these,
- 23:37you know, exhaustive epidemiologic,
- 23:39evaluations, you know, investigations to try to figure out if there's maybe
- 23:43another supplier, another food product that's being implicated,
- 23:47and if you have cases all over the country,
- 23:49you know, they can trace the one supplier, but there's concern that there might
- 23:52be, you know, other sources, and it's a lot of work.
- 23:57There are also, as we know, there have been a lot of cuts to personnel at the CDC.
- 24:03I was reading that instead of the cyclosporiasis unit, I guess,
- 24:07I don't know what they call them, they got cut down from 13 people or 12 people down to three.
- 24:12These are truly affecting the you know messaging whether there's timely messaging
- 24:17the number of people with expertise the number of people who have hands-on ability
- 24:21to do these investigations all this stuff does affect the numbers that we're getting,
- 24:26in this case and maybe the ability to you know identify them and then you know
- 24:30when you identify them then recalls can be,
- 24:33you know issued and then of course you have to have the people who are selling
- 24:36the product you know follow through.
- 24:38I think a combination of that, the distribution of this product,
- 24:41maybe the amount of, you know, parasite on there, and also,
- 24:45the fact that we have more readily available tests, more public health awareness
- 24:50will amplify the number of identified cases as opposed to what we would have
- 24:54had as maybe unidentified cases.
- 24:56Since washing doesn't reliably remove it, what should families actually do?
- 25:00Are you saying cooking produce right now is the only truly safe option?
- 25:05And is it realistic to expect restaurants to cook lettuce rather than serve it raw?
- 25:10I don't think restaurants are going to cook lettuce. And I think as long as
- 25:12the product isn't recalled, they're going to continue to serve lettuce.
- 25:15I think it's like an individual's decision of what they're going to eat.
- 25:19You know, when I got that lettuce at home and I rinsed it, I felt totally comfortable with that.
- 25:24You know, you have your own role in food safety, food preparation at home if you're cooking.
- 25:30And, you know, if there's a recall, you know, you could be, you could be,
- 25:34my cilantro could have maybe been contaminated. I just didn't know about it.
- 25:36So I just have to mitigate that risk by properly, you know, preparing and managing it.
- 25:41I will admit that I actually love Taco Bell, which is kind of embarrassing maybe.
- 25:46And I'm not, this is not a plug for them or against them. But,
- 25:50you know, I didn't go and get my, you know, occasionally I will go.
- 25:52I don't go all the time to get, you know, Taco Supreme, which,
- 25:55you know, might have lettuce on it. I was like, well, maybe I shouldn't eat that.
- 25:58You know, so like that's how much I'm changing my eating patterns,
- 26:01which is pretty minor. So you're not getting lettuce at Taco Bell.
- 26:04Well, I didn't go to Taco Bell at all since this happened.
- 26:07But, you know, this actually, I love the fact that I can't remember what year
- 26:10it was. I should have looked this up.
- 26:12There was an outbreak of E. coli that was associated with Taco Bell years and years ago.
- 26:17And they did this investigation and they took all green onions off of their
- 26:22products. And I was like, mad because I like the green onions.
- 26:25And then ultimately it turned out it was actually iceberg lettuce that caused that outbreak.
- 26:29So, you know, it's not necessarily Taco Bell or a fast food restaurant per se.
- 26:34It's just this mass distribution of a product that they don't know is contaminated,
- 26:39and is going to affect people until after maybe thousands of people have eaten
- 26:43it, you know. And so there's always going to be that lag. I mean, as y'all know. So...
- 26:49Bottom line, I appreciate how you tell us, like, but I'm not doing this.
- 26:53This is the advice because you're more relaxed.
- 26:56You know that there's a risk to a lot of things. Is that what goes into that?
- 27:00I mean, I'm not going to stop eating produce. I mean, if there's a recall, I wouldn't eat it.
- 27:04We all know how healthy it is for us. Yeah, if you have a young kid,
- 27:07and iceberg lettuce is actually not that healthy for you.
- 27:10It's like zero nutrients, but, you know, darker greens and berries,
- 27:13people really want to do that.
- 27:15I mean, I'm not telling people to change their eating patterns, but just to be aware.
- 27:19And I'm just telling them maybe to watch their food preparation.
- 27:23And then whether you go to a restaurant and eat a salad, like,
- 27:26would I go to a restaurant and eat a salad? Yes.
- 27:28If I have young kids that, you know, happen to eat vegetables and they may be,
- 27:33a toddler, you know, I don't know, I used to try to make my kids do that.
- 27:38Maybe you want to skip that. Maybe you want to give them some alternate vegetable
- 27:41that's cooked, you know, if they'll eat that.
- 27:43But if we start having more investigations into more sources and,
- 27:48you know, you start implicating more foods, why would we change the way we're
- 27:52behaving if the recalled product has been removed? Well, because maybe we don't
- 27:55have as much trust in, you know.
- 28:00In the food chain or the product chain and the testing and the reporting and
- 28:06the transparency. You know, I feel like maybe this could be a bigger problem,
- 28:10in the future. And I'm just going to say, you know, if you cut public health...
- 28:15You know, funding in employees. And this funding actually affects local health departments too.
- 28:19You know, grant money, if you don't have grant money, these people cannot do
- 28:22these investigations. They can't do the testing.
- 28:25So it's a reality. And maybe things are going to be like this or get worse. And I don't know.
- 28:31So, and as we all know, it's such a struggle.
- 28:35My last question about this outbreak, to get kids, and even for all of us,
- 28:40to really, are you getting enough fruits and vegetables.
- 28:43And I know pediatricians try to counsel patients about less fast food and eating
- 28:48more fruits and vegetables.
- 28:50But is this kind of setting us back where it's become such a worry nationally?
- 28:56I mean, I guess everybody can make that decision for themselves in terms of
- 28:59the risk assessments. But this is kind of how things are in a lot of other countries.
- 29:05Like I said, you counsel people when they're traveling not to do things like
- 29:08eating. In a lot of countries, people will actually wash their produce in various
- 29:14products that may have chlorine in them. Now, again, I said that's not going
- 29:17to work for this particular organism, but.
- 29:20Cooking all vegetables, peeling all vegetables is the safest thing to do if
- 29:26you're in a country where there may be less regulation, there may be more high
- 29:30risk of diarrheal pathogens at baseline.
- 29:33So I think that we're not there. I mean, I think we actually had a response
- 29:38and a recall, and recall the products, but as I said, you know,
- 29:42the recall happens after people have eaten it, so I think...
- 29:46You know, just do your part, you know, in terms of the things I said about the
- 29:50rinsing. I mean, those are just, you know, they're common sense things,
- 29:52but people don't always do it. They don't always follow through on that.
- 29:55And rinsing can reduce your risk.
- 29:57Yeah, it's going to reduce your risk of everything. There is no recommendation
- 30:00in this country to start using any kind of like dilute chlorine type of washing,
- 30:05you know, as people do other places. In general, that's not currently recommended.
- 30:10My sister-in-law's from another country, and she only eats cooked vegetables
- 30:13and is very careful about that and even cooks lettuce.
- 30:18Yeah, I mean, I think that that's because they grew up knowing that you'll get diarrhea.
- 30:23The other thing about this is, you know, their cyclospora is much more endemic
- 30:28in a lot of other countries, but then we import the food.
- 30:31Could there be contamination in farms here? Yeah, that's possible.
- 30:35Or in plants? That's certainly possible. But if somebody has never had an infection
- 30:41before, you're a naive host, people are going to get worse with something like cyclospora.
- 30:47The cases are more severe than if you go somewhere where it's endemic and people
- 30:51have already had it. Okay.
- 30:54And Dina, shifting to rabies, with Bexar County confirmed as a state hot zone,
- 31:00what should pediatricians tell families about wildlife exposure risk,
- 31:04and when does a scratch or a bite warrant post-exposure prophylaxis?
- 31:09So we've had some interesting rabies issues here.
- 31:12Typically, bats have been the vast majority of the number of cases of rabies.
- 31:18You know, animals that have been confirmed to have rabies.
- 31:20Testing often occurs when someone finds a sick or dead animal or someone gets
- 31:24scratched or bitten they actually have been reporting that the equal number,
- 31:28of skunk and bat cases right now and there have been Fox cases that have been
- 31:33in the news in general if a kid is scratched without breaking the skin like
- 31:39for example let's say you have like,
- 31:41the most common thing is cats you know kids like to go play with you know an alley cat or a feral cat.
- 31:47If it's something very surface and it scratches the skin minimally,
- 31:51generally we don't recommend doing anything other than washing the site.
- 31:54If there's a puncture wound, you know, then that's different.
- 31:57If you get bitten by a feral cat and then you don't have, you know,
- 32:01you don't know the cat's vaccination status, there's consideration of,
- 32:05and dogs as well. You know, we have had rabies cases in dogs that were not vaccinated.
- 32:09Then they need to be assessed. They need to wash the site. They need to go in
- 32:12and see if that the health department recommends giving rig and vaccine.
- 32:16And they don't always recommend it depending on the situation.
- 32:19But we do know this gunk strain that's endemic to South Central Texas can cross
- 32:23over to cats. It sounds like it's been crossing over into foxes.
- 32:27So, yeah, according to the Express News in May, a young boy was bitten by a
- 32:33rabid fox in Hollywood Park. And that sounds terrifying. So close to home,
- 32:38yeah. Very close to home. Yeah.
- 32:41I mean, I don't know the exact details of how the kid encountered,
- 32:45but, you know, in general, a rabid animal is either going to shy away and,
- 32:50you know, they call it dumb rabies, avoid people, or it can be aggressive.
- 32:53And so most of the time it's attacking or there's a fight between a domestic
- 32:58dog, a pet, and one of those animals.
- 33:00I have, you like stories that are personal. So two mornings ago,
- 33:06or on Friday morning, actually, I needed to get up and get here early.
- 33:09I let my dogs outside and they both ran at a raccoon that was sitting next to
- 33:13my pool drinking out of it.
- 33:14And I'm yelling, my dogs are vaccinated, but I'm yelling at them and chasing
- 33:19them, but they're not going to listen to me and go back outside.
- 33:21So the raccoon got in the pool and swam back and forth about 20 times. The raccoon?
- 33:25Yeah, to get away from my dogs. And finally, the dogs kind of like got a little
- 33:29bit less interested so he was able to get out without being but I was like,
- 33:33okay I don't want my dogs to get in a fight with a raccoon they are up to date
- 33:36on rabies vaccines but you know then do I need to reassess you know how long
- 33:40it's been and that you know obviously don't want them to get hurt,
- 33:43and you know that's all I could think about was rabies you know and also you
- 33:46know just the injury and it took a long time to get that raccoon it was that
- 33:50abnormal behavior for the raccoon no I mean they probably goes there and drinks
- 33:54well you know I just happened to get up a little earlier.
- 33:56But if an animal is coming up to you I had a fox walk right up to me Right outside
- 34:01the dental building You know, a couple months ago Like walk right up to me The dental building?
- 34:06Yeah, the dental school Oh, wow And I was like,
- 34:09Okay, it's the middle of the day. What are you doing? So those are considered not normal behaviors.
- 34:14I'm not a little kid. I didn't try to pet it, you know, but I know lots of adults
- 34:17who do things like that, too.
- 34:19They try to, you know, wildlife is cute and they try to mess with it and little
- 34:23children are at higher risk.
- 34:25So a dog and a fox is not like a dog, even though they're related,
- 34:30but they're so cute. But don't think of them that way.
- 34:33They're so cute. But they are, you know, coyotes, foxes, skunks, especially bats.
- 34:39Those are the highest risk animals we have here. Any mammal can get rabies.
- 34:44But, you know, my backyard, squirrels were being really weird today,
- 34:47walking right up to me. But generally things like squirrels and mice and rats,
- 34:51are considered to not be at risk. and possums are not considered high risk.
- 34:56They're not good hosts for it. And they also usually die when they get attacked
- 34:58by rabid animals. So a lot of weird daytime wildlife stuff, and most of them probably are not rabid.
- 35:05But, you know, really telling the parents that we have cases.
- 35:09Bats are the biggest problem. I've dealt with so many kids over my career here
- 35:13in Bexar County with kids who are playing with bats. There's a dead bat. They picked it up.
- 35:18The bat was in the room. The classic story a bat was in the room and like somebody's
- 35:22camping it's in the cabin they wake up and you know could the kid have gotten
- 35:25bitten could you have you're supposed to actually give vaccine and
- 35:29rabies immunoglobulin to all those people even because even if they were licked
- 35:33by the bat while they were sleeping yeah theory you know like you could have salivary transmission,
- 35:39into the respiratory tract without a bite which is really.
- 35:42Not well established but you know usually it's a bite maybe that is so small that it's not noticed.
- 35:48And this is something I get calls about on a regular basis. It's usually bats.
- 35:53But also we get a lot of dog bites.
- 35:55And one thing, a comment I was going to make, I'm sure the pediatricians may
- 35:59not be dealing with this, but.
- 36:01You know, occasionally, if you get a bite on your, people know you get a bite
- 36:04on your face or your head, the rabies, if you do get exposed,
- 36:08you get the animals rabid,
- 36:10you're going to develop symptoms near your brain, and it's going to travel there
- 36:14much faster than it's on your, like, your foot or your hand.
- 36:17So I recently had a case where a kid, we have a lot of dog bites here in our
- 36:21trauma ICU, and I had a kid who was bitten on the head, and the animal was,
- 36:25you know, somebody else's animal, probably wasn't vaccinated, was being observed.
- 36:30And I said, I recommend it to the team, you know, then they don't routinely
- 36:33do this. You need to go ahead and just start the rabies series because even
- 36:36if you observe this animal for 10 days and they don't show symptoms,
- 36:40it is possible, you know, usually it's a few weeks to develop rabies.
- 36:44You have a few weeks like window, but you're really supposed to vaccinate people
- 36:47right away. And if it's on the head or the face, I would really be sort of aggressive
- 36:52about trying to get the health department to get vaccine and immunoglobulin.
- 36:56So a lot of times, you know, you'll send them to the emergency room.
- 36:59I've had people who did not go to the emergency room. It's like,
- 37:02where can I get it? You know, the MetroHealth is supposed to be coordinating
- 37:05this, but we do have these products in the ER.
- 37:07And then they'd have to get follow-up rabies shots after they get the initial
- 37:10dose. And that can be a little challenging.
- 37:12And at University Hospital, it's the only level one trauma center other than BAMC.
- 37:18And so you see a lot of these cases, as you mentioned.
- 37:22Is it too late to start treatment once someone shows signs of rabies? Oh, yeah.
- 37:27I mean, there's all kinds of concoctions and protocols people have used,
- 37:32but no, you need to develop immunity fast.
- 37:36You know, you need to get them vaccinated and rig into them like right away.
- 37:40And then also your advice is if an animal's acting strangely,
- 37:44stay away and don't try to pet an animal that's walking on the street that's
- 37:49in the woods. Yeah, don't try to put any animal you don't know.
- 37:51I mean, that's really, you think that adults would know that and have common
- 37:56sense. I've dealt with so many adults who just, you know, touched every animal
- 38:00they could find. What about a stray dog?
- 38:03You know, you really shouldn't touch them. I mean, I, you know,
- 38:06would I, you know, would I, would I touch a stray dog who came up and looked,
- 38:09you know, sick and, you know, I mean, that's a risk, right?
- 38:14I've already been vaccinated for rabies in the past when I was traveling.
- 38:16So, I mean, maybe I'm, I'm safer, but I definitely don't recommend talking to
- 38:22your kids, make sure they understand, like, you know, if you see a cat or a
- 38:25dog, just don't touch it.
- 38:26You know, I mean, if it's not somebody's pet that's been vaccinated,
- 38:29especially if it's acting weird And then the pediatrician's issue is that they
- 38:34just have to deal with it after the bite happens or the questionable bite or
- 38:37the questionable exposure. And that's when I usually get called.
- 38:41Yeah, there was a guy in my neighborhood and I was walking and his dog was off
- 38:46the leash. It kept getting unhooked from the collar, actually.
- 38:50And then so he needed help. So I ran over to help him. But I asked,
- 38:52I said, is your dog up to date on rabies?
- 38:56Oh, look at you. I know, look at me. Being careful. But he just looked at me
- 38:59like, you know, kind of offended or whatever. And he's like, yeah, I think so.
- 39:03I was just like, okay, well, I guess I'll go with that.
- 39:06Yeah, yeah. I mean, I definitely wouldn't let my, you know, wouldn't want my kids doing that.
- 39:10But yeah, they do quarantine animals when there's bites. Even if they're vaccinated,
- 39:15animal control has to make you fill out a form and you have to document the
- 39:20vaccine. But you also have to fill out a form if you want to keep your animal
- 39:22at home under quarantine.
- 39:24I'm kind of strict about that. Wow. The concern is like when you don't actually
- 39:28recognize a bite like from a bat or,
- 39:30you know, people don't go seek help right away.
- 39:34We have very, very few rabies cases in the United States, but you can get it.
- 39:40There's more cases here if you don't get your kid into the clinic,
- 39:44to the hospital, and get timely treatment, you know.
- 39:48And you have a special certification, a fellowship you did on tropical medicine?
- 39:52Yeah, it's not a fellowship. It's a certification for TropMed with AST Mitch.
- 39:56So basically, it's just additional training, and you know, you have to go to
- 40:00spend time overseas. You have to, you know, there's certain criteria,
- 40:03but it was really fascinating topic.
- 40:06It is so fascinating. Is there anything, Dina, you want to mention that we didn't
- 40:10cover these very different topics, but both so important right now?
- 40:17I just really, I just really have a lot of sympathy, you know,
- 40:21for the pediatrician who's got parents asking these questions all the time,
- 40:24and then they have to be up to date.
- 40:27But, you know, Follow what's going on and develop answers to these questions or research.
- 40:34But again, if you're limited on being able to test, the decision on whether
- 40:38to test somebody, it's similar to the decision whether you should send a kid to the ED for admission.
- 40:43You've got to assess the risks and then figure out if you can do anything about it.
- 40:48If the patient's like E. coli 0157, those are kids that may need closer monitoring,
- 40:54even if they don't need antibiotics.
- 40:55So, you know, if anybody has any feedback for me, they can always email me and
- 41:00say, hey, what are you talking about? We don't we don't do that. Or this is impossible.
- 41:04I'm always interested to hear.
- 41:06And so we'll include your email address in the text for the podcast.
- 41:10So we'd like to promote having a life outside of medicine.
- 41:14What do you like to do to unplug? I know you've talked about travel before,
- 41:17and you recently got back from Italy. Yeah, I got to go to Italy.
- 41:21I attended a conference in Bologna and then did a lot of traveling to different cities in Italy.
- 41:28We drove up into the Dolomites. We went to Venice. We went to Florence.
- 41:34It was pretty cool. Wow. And the food was generally very good.
- 41:38There was some food that was like, I'm disappointed I'm eating this in Italy, but I ate a lot of pizza.
- 41:42It was fantastic. It was very good. And do you want to mention,
- 41:46I also, on Pediatrics Now, I love quotes. Is there a favorite quote?
- 41:50I would like to share a quote or two about public health, since that's what we're talking about.
- 41:58And not worrying or worrying?
- 42:01It's not a worry one. It's more like an ethical one. Okay. So one is C.
- 42:05Everett Koop, who was the Surgeon General back in the 80s to 90s,
- 42:10I think. I can't remember the dates.
- 42:12It's healthcare is vital to all of us some of the time, but public health is
- 42:15vital to all of us all of the time.
- 42:18The other one I wanted to share was by Dr. Martin Luther King Jr.
- 42:23Of all forms of inequality, injustice in health is the most shocking and inhumane.
- 42:29Will you say it again for us? I like that one. That was too fast.
- 42:35Of all the forms of inequality, injustice in health is the most shocking and inhumane.
- 42:41So that's not specifically public health, but it's a great quote for us to think
- 42:47about. As pediatricians, we really believe everybody should have access to health.
- 42:52I'm sorry. Pediatricians are the best people. They're good people. Amazing.
- 42:56Dedicating their lives. I love them. Making the world a better place.
- 43:00They are. That's wonderful.
- 43:03Dr. Dina Sutter with UT Health San Antonio Infectious Disease and University
- 43:08Health, thank you so much for being here again on Pediatrics Now. Thanks, Molly.
- 43:14We need to do these regular segments. There's always so much going on.
- 43:17Click on the link in this podcast for a free credit that may include CME,
- 43:21MOC, or ethics credit, depending on our topic or podcast.
- 43:25Coming up next week, I'll take you to the surgical unit at University Hospital,
- 43:31and you'll see behind the scenes a baby whose life was changed for the better.
- 43:36An update on plastic surgery coming up next week on Pediatrics Now.
- 43:41I'm Holly Wayment. I'll see you soon.