1019-Cell Death in Cancer

Paper Talk · May 23, 2026 · 21m

This review article examines the complex landscape of regulated cell death and its critical role in cancer development, progression, and treatment. While apoptosis has long been the primary focus of oncology, the authors highlight how emerging pathways like necroptosis, pyroptosis, and ferroptosis provide new opportunities to overcome therapy resistance. These diverse death programs do not function in isolation; instead, they form an interconnected network that influences the tumor microenvironment and the effectiveness of the immune system. By understanding how malignant cells evade these…