Including People with Suicidal Ideation/Behavior in CNS Trials
In this episode of Mind the Methods (the ISCTM podcast), Dr. Mark Opler speaks with Dr. Elizabeth Ballard, Associate Scientist at the NIMH Intramural Research Program and the 2025 recipient of the ISCTM Lewis Alan Opler Prize, about the evolving science of suicidal ideation and behavior. Dr. Elizabeth Ballard explains why many commonly used tools were built for risk documentation and legal protection, not for detecting treatment-related changes in clinical trials, and how repurposing them can obscure true signals, particularly for rapidly acting interventions. Drawing on trial examples, Dr…
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