Latest / Pharmacy Podcast Network / Rewriting the Script: Pharmacogenomics in Pharmacy’s Future with Dr. Vanessa Lesneski | Precision Medicine Pharmacist Podcast
Transcript
- 0:05Speaker 1: You are listening to the global network of podcasters dedicated
- 0:09Speaker 1: to the pharmacy profession.
- 0:10Speaker 2: Welcome to the Pharmacy Podcast Network.
- 0:24Speaker 3: Welcome to another episode of the Precision Medicine Pharmacist on
- 0:27Speaker 3: the Pharmacist Podcast Network. I'm your host, doctor Melissa Smith,
- 0:31Speaker 3: and today we are diving into a critical and exciting
- 0:34Speaker 3: conversation about the evolution of pharmacogenomics and what it means
- 0:38Speaker 3: for the future.
- 0:39Speaker 4: Of our profession.
- 0:42Speaker 3: Our guest is a true leader in the space, doctor
- 0:44Speaker 3: Vanessa Lesnewski. She is a pharm d and a dedicated
- 0:48Speaker 3: educator at the Lee Coom School of Pharmacy and a
- 0:51Speaker 3: pioneer in the implementation and innovation of PGX and clinical practice. Together,
- 0:56Speaker 3: we'll explore how pharmacy education is adapting and what new
- 1:00Speaker 3: career paths are opening up, and why now more than ever,
- 1:04Speaker 3: pharmacists must take control of their role and guiding in
- 1:08Speaker 3: the interpretation and application of this genetic data. Vanessa, you
- 1:13Speaker 3: are a dear friend to me, but also is an
- 1:16Speaker 3: honor to have you on this episode today.
- 1:18Speaker 4: So first of all, welcome.
- 1:21Speaker 2: Thank you. I'm happy to be here.
- 1:23Speaker 4: Oh yes, I'm happy to have you here.
- 1:25Speaker 3: Give a brief overview and just introduce yourself to the
- 1:28Speaker 3: audience because I'm sure that they are wanting to hear
- 1:30Speaker 3: a little bit more.
- 1:31Speaker 2: All right, So I am doctor Vanessa Lesnaski.
- 1:34Speaker 1: I started my pharmacy journey at the University of Florida,
- 1:40Speaker 1: got my doctators there Gators, and from there I did
- 1:46Speaker 1: a little small stint in retail, but that wasn't quite
- 1:49Speaker 1: for me, which honestly was surprising because I had waited
- 1:52Speaker 1: tables a lot before that, so I thought that that
- 1:55Speaker 1: was going to be a good fit.
- 1:55Speaker 2: But you know, love when you learn.
- 1:58Speaker 1: So from there, I had the awesome opportunity need to
- 2:00Speaker 1: work for a pharmacy benefits manager. I mean, I did
- 2:02Speaker 1: a lot of their escalated cases as a clinical pharmacist
- 2:05Speaker 1: for them, so that was super fun and that really
- 2:07Speaker 1: just kind of ignited my passion for like diving in
- 2:10Speaker 1: deeper for patients. From there, I had a very exciting
- 2:15Speaker 1: opportunity to work for a startup in pharmacogenomics. And what
- 2:21Speaker 1: had happened was my mom's friend's sister was sitting next
- 2:25Speaker 1: to somebody on an airplane.
- 2:26Speaker 2: So sometimes it is not what you know who you know.
- 2:30Speaker 1: I think you need to have the way really, So
- 2:34Speaker 1: I entered the world of pharmacogenomics kind of like on
- 2:37Speaker 1: the spot. I really just did a lot of digging
- 2:39Speaker 1: and learning on my own and jumped in as a
- 2:42Speaker 1: subject matter expert for.
- 2:43Speaker 2: A startup company. And we had a lovely run.
- 2:47Speaker 1: But we were a startup company and you know, things
- 2:50Speaker 1: shifted as far as the payment reimbursement goes, and unfortunately
- 2:55Speaker 1: that company kind of collapsed. Eventually it morphed and then morphed,
- 3:00Speaker 1: and but you know, the vision is still alive. And
- 3:04Speaker 1: as from there, I went to and worked for compounding pharmacy,
- 3:07Speaker 1: which was super fun for all your pharmacists out there, Like,
- 3:10Speaker 1: if you were trying to find something that as you're calling,
- 3:13Speaker 1: definitely take a look at compounding. That was super fun.
- 3:15Speaker 1: I really enjoyed it. It was like being a cook
- 3:18Speaker 1: in the kitchen.
- 3:19Speaker 2: You know, and your technicians are your lifeline there. I
- 3:24Speaker 2: didn't really know their stuff, so that was that was
- 3:27Speaker 2: really fun.
- 3:28Speaker 1: But I got to set up a nutrition program for them,
- 3:30Speaker 1: so I had a really fun little wormhole there.
- 3:34Speaker 2: So now I've got two wormholes. I've got pharmacogonomics and
- 3:37Speaker 2: a nutrition wormhole that.
- 3:38Speaker 1: I have gone down and a friend of mine suggested
- 3:42Speaker 1: that I come work with her at Lake Erie College
- 3:44Speaker 1: of Osteopathic Medicine in their School of Pharmacy in Bradenton, Florida.
- 3:50Speaker 1: So I was like, well, that sounds interesting and different.
- 3:53Speaker 2: So I kind of jumped.
- 3:54Speaker 1: In and I started there and I've been there for
- 3:59Speaker 1: eight years and I have done a couple of fun,
- 4:03Speaker 1: interesting things. I started an elective that's super unique. It
- 4:07Speaker 1: was the first one of its kind and in the
- 4:10Speaker 1: United States.
- 4:11Speaker 2: And functional medicine, but that's not what we're here to
- 4:13Speaker 2: talk about, no.
- 4:14Speaker 4: But it is applickable, it's appliable there ye, So, like this.
- 4:18Speaker 1: Concept of personalized medicine is really out there, and you know,
- 4:22Speaker 1: that's part of what functional medicine is. And so for
- 4:25Speaker 1: the people that are listening, functional medicine, the quick and
- 4:28Speaker 1: dirty definition is it is looking at the root cause
- 4:31Speaker 1: of disease. So why is your patient, you know, why
- 4:35Speaker 1: are they having the issues that they're having, What is
- 4:37Speaker 1: actually causing that? And how do we reverse it? Support it?
- 4:41Speaker 1: You know, change and.
- 4:42Speaker 3: The DNA is a very foundational cause, right.
- 4:48Speaker 2: Yeah. So strangely enough, my two little niches.
- 4:51Speaker 1: Fit together really nicely because at the end of the day,
- 4:54Speaker 1: everybody's an individual, right, Like you and I could go
- 4:57Speaker 1: out to a restaurant and we're going to order something
- 4:59Speaker 1: different off the menu because we're different people. So we're
- 5:03Speaker 1: at the same restaurant, we're having the same experience, but
- 5:05Speaker 1: we're eating different foods, so we're all different. So that
- 5:09Speaker 1: kind of like both of those things marry very nicely.
- 5:13Speaker 1: So anyways, so yeah, So then circling back forward, I
- 5:16Speaker 1: had that wonderful experience working with the genetics company, so
- 5:22Speaker 1: I brought that experience with me to teaching, which the
- 5:25Speaker 1: students really enjoy hearing about that. So at that company,
- 5:30Speaker 1: to kind of go backwards, that company was really trying
- 5:33Speaker 1: to give doctors an actionable report because you know, a
- 5:38Speaker 1: genetic report is kind of.
- 5:39Speaker 2: Rough to read.
- 5:40Speaker 1: Yes, So so that's kind of like where I am.
- 5:45Speaker 1: So I've spent the last years in education, which is
- 5:48Speaker 1: I think phenomenal. It's a perfect fit for a lot
- 5:50Speaker 1: of pharmacists because we are constantly educating patients on what
- 5:56Speaker 1: it is that they need to take from their medication
- 6:01Speaker 1: and what they need to do with their medications. So
- 6:02Speaker 1: we are natural educators. So I've really enjoyed it being
- 6:07Speaker 1: an educator. So yeah, that's my story is gone along.
- 6:10Speaker 4: It's a great story.
- 6:11Speaker 3: It gives perspective that you don't always you know, land
- 6:14Speaker 3: where you think you're going to when you initially start
- 6:17Speaker 3: your career. You've got to be able to be adaptive
- 6:19Speaker 3: and pivot and explore other options to make yourself that
- 6:22Speaker 3: much more rounded and capable as a pharmacist as well.
- 6:26Speaker 3: So that's so cool. I'm glad you shared that. But
- 6:29Speaker 3: you also within teaching you provide pharmacogenomics within the curriculum
- 6:36Speaker 3: and that's correct, yes, correct, So.
- 6:39Speaker 1: The there is you know, for the accreditation process, one
- 6:43Speaker 1: of the requirements is to include some pharmacogenomics. Now, the
- 6:47Speaker 1: accreditation process, the body that governs that, they're not very
- 6:51Speaker 1: very specific about exactly what needs to be in the
- 6:53Speaker 1: curriculum as far as pharmacogenomics, but it does need to be. Yeah,
- 6:57Speaker 1: So you know a lot of schools undergone curriculum changes
- 7:01Speaker 1: we did in twenty twenty one, I believe, and you.
- 7:05Speaker 2: Know we've gone to this module program.
- 7:08Speaker 1: Our previous curriculum had a scandalone to credit course in pharmacogenomics.
- 7:12Speaker 2: Now we have the pharmacogenomics.
- 7:14Speaker 1: Built into each module for the different disease states. But
- 7:19Speaker 1: then we also have like a little bit of introduction to.
- 7:21Speaker 2: Genetics in our early first year.
- 7:24Speaker 1: Classes, and then it is also built into some lectures too,
- 7:29Speaker 1: so we still include it. It's just not a scandalone course,
- 7:34Speaker 1: I would like to see that beefed up a little bit,
- 7:37Speaker 1: So that's probably my responsibility at least. Also, you know,
- 7:43Speaker 1: I think there needs to be a little bit more
- 7:46Speaker 1: governing and we need to kind of I think pharmacists
- 7:48Speaker 1: do need to take a moment and come together and
- 7:50Speaker 1: stay with that.
- 7:51Speaker 3: Looks for there's quite a few around the country, especially
- 7:54Speaker 3: getting into the PGUI two rotations for pharmacists as well,
- 7:57Speaker 3: offering more of.
- 7:58Speaker 4: Those as well.
- 8:01Speaker 3: So it's it's definitely becoming more of a concentrated focus
- 8:06Speaker 3: and a specify and I see it becoming a specialty
- 8:11Speaker 3: under pharmacy here in the near future.
- 8:13Speaker 4: There's a lot of different things.
- 8:14Speaker 2: Yeah, so that's a double edged short.
- 8:15Speaker 1: That's funny that you bring that up, because that was
- 8:17Speaker 1: one of the things on the list of questions that
- 8:19Speaker 1: you had about the training. So you know, we have
- 8:25Speaker 1: a lot of board certifications already, so I could actually
- 8:28Speaker 1: argue this both ways. So I do like the idea
- 8:32Speaker 1: of pharmacists specializing in pharmacogenomics.
- 8:34Speaker 2: I think that we need more knowledge and education out there. However,
- 8:40Speaker 2: I worry that, you know, with with the cost of everything.
- 8:44Speaker 1: Increasing, pharmacy salaries are pretty much staying stagnant, which is.
- 8:47Speaker 2: Okay, it's a good salary, but you know, you have
- 8:50Speaker 2: to be careful.
- 8:51Speaker 1: And then when you start to get these different certifications.
- 8:54Speaker 2: You have to pay for the update, the yearly update
- 8:56Speaker 2: of those sort of Oh.
- 8:57Speaker 3: Yes, definitely, different licensers require different different types of fees
- 9:02Speaker 3: and all types of continuing education around it too, yep.
- 9:06Speaker 1: Right, so that that's just more money at somebody's pocket.
- 9:09Speaker 1: And I just worry sometimes of all these certifications are
- 9:12Speaker 1: a little bit not to be negative, but a little
- 9:14Speaker 1: bit of a business. Yeah, So I think we should
- 9:16Speaker 1: be careful.
- 9:16Speaker 3: It's in our intuitive nature as a pharmacist as well
- 9:20Speaker 3: to already be incorporating this type of thought process in
- 9:24Speaker 3: our verification. Right, So, thinking about the pharmacokinetics, we see
- 9:28Speaker 3: it all the time. You see it when you're verifying,
- 9:29Speaker 3: even at the retail level with omeprazol and cliputogrel. Big
- 9:32Speaker 3: interaction there for it not activating clip putogrel from the
- 9:35Speaker 3: twocent nineteen inhibition. So we're already got that concept. It's
- 9:39Speaker 3: just remembering that concept as the genetics come into play.
- 9:42Speaker 3: It's it's the same concept, it's just the genetic role
- 9:45Speaker 3: as opposed to the drudgia drug interaction role. But yeah,
- 9:50Speaker 3: and this kind of leads me into exactly kind of
- 9:52Speaker 3: your point there with like the cost of thing like
- 9:54Speaker 3: the cost of tuition, different things. We've seen a significant
- 9:58Speaker 3: decline in pharmacy school enrollment really and applications drop from
- 10:01Speaker 3: over yours a statistic around one hundred thousand and twenty
- 10:05Speaker 3: eleven to just around forty thousand by twenty twenty one,
- 10:08Speaker 3: and the number of new graduates in twenty twenty two
- 10:10Speaker 3: fell to a forty year look.
- 10:13Speaker 4: So that's interesting.
- 10:15Speaker 3: So what do you think aside from yes, cost is
- 10:20Speaker 3: a big one, anything driving this downturn? And how do
- 10:24Speaker 3: you see PGX potentially reigniting the interest in pharmacy as
- 10:28Speaker 3: a forward looking, tech savvy.
- 10:30Speaker 4: Profession for pharmacists. It's a big question, right, yeah, cop it.
- 10:37Speaker 2: Okay, So let's first the part about you know, the
- 10:42Speaker 2: downturn in but that's that's really being driven by jobs.
- 10:46Speaker 1: Yes, great, so I have sat on omissions for more
- 10:50Speaker 1: years than not at leak hom I adore.
- 10:53Speaker 4: Yeah, you have a good perspective on this.
- 10:56Speaker 2: It's my favorite committee. But it is a hard committee.
- 11:00Speaker 1: Is the time consuming, but it's it's really exciting committee
- 11:04Speaker 1: because I like to look at the applicants and you know,
- 11:08Speaker 1: the current students, and.
- 11:10Speaker 2: You get really excited about it. But and also I
- 11:13Speaker 2: also like recruit like recruitment too, like to do the activities.
- 11:17Speaker 1: But so one of the one of the reasons, and
- 11:20Speaker 1: we've been seeing this trend for for longer.
- 11:23Speaker 2: Than the statistics have shown because those of us that work.
- 11:26Speaker 4: In you see it.
- 11:27Speaker 2: Ye it.
- 11:29Speaker 1: So in twenty fourteen, when I work for the pharmacy
- 11:31Speaker 1: benefits manager, that entity, the local pharmacy that was was
- 11:35Speaker 1: here folded and we dumped three hundred pharmacists out into the.
- 11:40Speaker 2: Job market Campa Bay, yep market.
- 11:43Speaker 3: So it almost flooded it. Too much availability and not
- 11:47Speaker 3: enough job availability, all.
- 11:50Speaker 1: Right, So what we're seeing is a result of automation.
- 11:53Speaker 1: So it started much earlier and then the trends are
- 11:56Speaker 1: catching up. So we you know, the the idea of
- 12:00Speaker 1: a pharmacist standing you know, in a pharmacy at the
- 12:02Speaker 1: extra corner and the lick stick and poor, which many
- 12:06Speaker 1: pharmacists went and know what it means.
- 12:07Speaker 2: But you know they used to lick the labels to
- 12:09Speaker 2: stick them on there.
- 12:11Speaker 1: Yes, the on there right, and they would do them
- 12:16Speaker 1: with talk writers, right like I work with people who
- 12:19Speaker 1: who have you know recently, well not recently, but when
- 12:22Speaker 1: I first started working, there a people that were talking
- 12:23Speaker 1: about that. It wasn't that long ago, so you know,
- 12:26Speaker 1: there was so pharmacy feeling of prescription was very manual.
- 12:29Speaker 1: Now we have more and more automation to do.
- 12:33Speaker 2: That, right.
- 12:33Speaker 1: And then you know, when I was starting pharmacy, you
- 12:38Speaker 1: know the ninety days supply was only available through insurance companies.
- 12:41Speaker 2: Now we have those.
- 12:42Speaker 1: Available through any any pharmacy. So so the trends in
- 12:47Speaker 1: the are changing.
- 12:49Speaker 2: Uh. There's just a lot of automation.
- 12:51Speaker 1: So you know, the manual labor aspect of it is
- 12:54Speaker 1: kind of going away. We've also changed the pharmacist of
- 12:57Speaker 1: tech ratios, yes, because there is is better ways of
- 13:01Speaker 1: checking the prescription even if you're not the one filling it.
- 13:05Speaker 1: So the aspects of that have been monitored have been.
- 13:09Speaker 2: Automated. Uh.
- 13:12Speaker 1: And so you know a lot of automation, a lot
- 13:16Speaker 1: of changing of the pharmacist's responsibilities.
- 13:19Speaker 2: And honestly, pharmacists.
- 13:21Speaker 1: Now are being educated on the level of a clinician,
- 13:25Speaker 1: but when we get out into the job market, we're
- 13:26Speaker 1: not being treated like a commission.
- 13:29Speaker 2: You know, it's a four year doctorate program. I don't
- 13:31Speaker 2: have to tell you.
- 13:33Speaker 1: But when that originally came about, the idea was for
- 13:37Speaker 1: pharmacists to be providers. So the fact that we didn't there,
- 13:44Speaker 1: we didn't have like.
- 13:46Speaker 3: The the the education level isn't translating into the jobs available, right.
- 13:52Speaker 2: Correct, So you know, so we.
- 13:57Speaker 3: I feel like this is where the PGAX element is
- 14:00Speaker 3: an opportunity for job growth, for pharmacists to be.
- 14:03Speaker 4: Utilized as more of a clinician. I see where you're going, yes, And.
- 14:11Speaker 3: I feel like I have a lot of people reach
- 14:13Speaker 3: out to me just in general about what I do
- 14:15Speaker 3: to be active in the PGX space and how I
- 14:19Speaker 3: am contributing and still able to apply the knowledge right
- 14:23Speaker 3: And I.
- 14:23Speaker 4: Tell them A lot of these jobs are on the
- 14:26Speaker 4: back end.
- 14:26Speaker 3: A lot of them are with the report generation companies
- 14:29Speaker 3: and also with the laboratories themselves, helping to support the
- 14:32Speaker 3: providers who are ordering the patients who are receiving the
- 14:35Speaker 3: information as well and providing clinical counseling, applying it in
- 14:39Speaker 3: my own private practice as well as how I utilize
- 14:42Speaker 3: it the most. But I think in more and upcoming years,
- 14:47Speaker 3: we're going to see a shift in that dynamic in
- 14:49Speaker 3: the pharmacist supporting a provider with the interpretation of these results.
- 14:54Speaker 3: And we all know the reason for that is because
- 14:57Speaker 3: many of them are not trained and it's not their
- 14:59Speaker 3: fault to not understand this information. But we need to
- 15:03Speaker 3: align the stars when it comes to reimbursement at a
- 15:07Speaker 3: level like that for pharmacists to be paid for their
- 15:09Speaker 3: time to do this service as well.
- 15:11Speaker 4: So that's where I.
- 15:12Speaker 3: See the gap, and I'm sure you can appreciate that
- 15:16Speaker 3: whole level of conversation.
- 15:19Speaker 2: So total nail on the head, right.
- 15:21Speaker 1: So we have these pharmacists that are being educated on
- 15:24Speaker 1: the level of the clinician, they're getting out of school,
- 15:27Speaker 1: and then they're fulfilling these roles that are are being
- 15:30Speaker 1: taken away by automation, and rightfully so, I mean they
- 15:33Speaker 1: are trying to.
- 15:34Speaker 4: Hire maybe filling the pills, you know what I mean.
- 15:37Speaker 1: The pharmacist is a little bit I mean, but you know,
- 15:40Speaker 1: there are a lot of clinical tools that they need
- 15:43Speaker 1: even a dispensing pharmacies needs I'm.
- 15:45Speaker 4: Going to ask another end point where they need it.
- 15:48Speaker 2: They're not fl filling their clinical roles.
- 15:49Speaker 1: But there are those of us who want to practice
- 15:52Speaker 1: at the top of our licenses. As you can see
- 15:54Speaker 1: from my credentials, I do have a consultant pharmacist license
- 15:58Speaker 1: on top of my registered pharmacist license. In order to
- 16:01Speaker 1: be able to be at the top of my license,
- 16:03Speaker 1: I am on on file with the board or a
- 16:05Speaker 1: collaborative practice agreement. I don't currently have one in place,
- 16:09Speaker 1: but you know, to be able to practice at the
- 16:11Speaker 1: top of our licenses and give that give patients the
- 16:16Speaker 1: clinical expertise that we have, and the clinical expertise that
- 16:19Speaker 1: we have is that we understand the nuances of the
- 16:22Speaker 1: different medications. So for example, you know your patient needs
- 16:26Speaker 1: a beta blocker, Well, which one? Which one you pick?
- 16:29Speaker 1: You don't necessarily it may not be the right drug.
- 16:33Speaker 4: It's not protocolo picking it.
- 16:37Speaker 1: Yeah, you're picking the one where the where the salesperson
- 16:39Speaker 1: was just in the office like that may or may
- 16:41Speaker 1: not be the right It might be the right drug
- 16:43Speaker 1: for that page. Yeah, you know, but it might to say,
- 16:47Speaker 1: and I do think that pharmacists should have that role
- 16:51Speaker 1: where we are either vetting or picking the therapy for
- 16:54Speaker 1: the papient, you know, because we have the expertise to
- 16:58Speaker 1: say that.
- 16:59Speaker 2: And then when you pull in pharmacogenomics, so maybe pharmacogenomics
- 17:03Speaker 2: becomes our lifeline to say, hey, you really need us
- 17:06Speaker 2: on staff picking the fantasies because you know, in order
- 17:09Speaker 2: to apply pharmacogenomics. And I don't I mean, I don't
- 17:12Speaker 2: know what your viewership consists of, but if they.
- 17:15Speaker 3: It's a it's a pharmacists and practitioners wanting to just learn,
- 17:20Speaker 3: get more knowledge based, and just be up to snuff
- 17:22Speaker 3: with the information out there about it.
- 17:25Speaker 1: Okay, So the pharmacogenomics that we have at our fingertips
- 17:28Speaker 1: right now is regarding metabolism. So you know, really at
- 17:34Speaker 1: the end of the day, you're looking at pharmacokinetics.
- 17:37Speaker 2: Now.
- 17:37Speaker 1: I do not anticipate a doctor to be able to
- 17:40Speaker 1: have all the things that they've learned about diagnostic tools
- 17:45Speaker 1: and diagnosing a patient and evaluating a patient and hold
- 17:49Speaker 1: all that from a CoKinetic information and I can do that.
- 17:53Speaker 1: I'll over here on the pharma coconic side, right like,
- 17:56Speaker 1: so you know, having that pharmacist at least way in
- 18:00Speaker 1: and say, hey, you know, this will work best for
- 18:03Speaker 1: the patient based on the other medications they're taking, based
- 18:06Speaker 1: on their kidney clearance, based on their nutrition status, based
- 18:11Speaker 1: on their activity level, gender, even and potentially pharmacogenomics. So
- 18:17Speaker 1: I do think that, you know, in order for us
- 18:19Speaker 1: to be thoughtful and individualized therapy, we do need to
- 18:23Speaker 1: make sure that pharmacists are getting paid for their time.
- 18:25Speaker 2: There's no other way to make that.
- 18:27Speaker 4: Yes, that's where I see the future going with it.
- 18:30Speaker 3: And honestly, it has to be built internally within the
- 18:33Speaker 3: structure of the payment systems with the insurance companies, right,
- 18:36Speaker 3: So it's.
- 18:38Speaker 1: Yeah, we're not going to get any traction until we
- 18:40Speaker 1: start get paid for our time. However, if you noticed
- 18:44Speaker 1: insurance rates are significantly going up for a lot of
- 18:46Speaker 1: patients in the coming.
- 18:47Speaker 4: Year, didn't notice, I'm glad you brought it up.
- 18:51Speaker 1: Yeah, So I also am wondering if patients are going
- 18:55Speaker 1: to start to get and it's going to be patient driven.
- 18:57Speaker 1: So patients start to get fed up with the cost
- 18:59Speaker 1: of copays insurance premiums where.
- 19:04Speaker 4: They might just go to private pay.
- 19:06Speaker 1: Forget to go to private pay, just pay for them themselves,
- 19:10Speaker 1: in which case a patient may be willing.
- 19:12Speaker 2: To pay us, you know, to do this for them,
- 19:15Speaker 2: because it will.
- 19:16Speaker 1: I mean every study they've ever done when you insert
- 19:19Speaker 1: a pharmacist in the middle of her as far as
- 19:22Speaker 1: fulfilling a clinical role brings, brings down cost, increases better outcomes,
- 19:27Speaker 1: and decreases adverse effect events.
- 19:30Speaker 4: Absolutely, definitely, we.
- 19:33Speaker 2: Have the data to back ourselves up for sure.
- 19:36Speaker 4: And yes, I can't agree with you more on that.
- 19:39Speaker 2: And you know when'ts are hungry to learn these new things, right.
- 19:42Speaker 4: Well, yes, that's you brought me right into my topic.
- 19:45Speaker 1: I mean I just say the word pharmacogenomics and like
- 19:49Speaker 1: half the class's.
- 19:49Speaker 2: Eyes light up.
- 19:51Speaker 4: Tell me more.
- 19:52Speaker 1: Yes, Yeah, it's exciting and it's it's it's it's it's
- 19:56Speaker 1: a nuance to pharmacy. So it makes us stand out,
- 20:00Speaker 1: Like I mean, you know, doctors and nurses, they know
- 20:02Speaker 1: what a beta blocker is, and they know what a
- 20:04Speaker 1: beta blocker does.
- 20:05Speaker 2: You know, we're the ones that know how beta blocker's metabolized, right.
- 20:09Speaker 1: So it makes us you know, it's it's unique to us,
- 20:13Speaker 1: and it just excites students and it's it's cutting edge.
- 20:17Speaker 2: So I mean, but the same with functional medicine too.
- 20:20Speaker 1: I thought that students would think I was off my
- 20:22Speaker 1: rocker when I first started introducing little nuggets of functional
- 20:25Speaker 1: medicine in my lectures.
- 20:27Speaker 2: And they love it. They just ask for more.
- 20:29Speaker 1: I had one course where I was supposed to be
- 20:32Speaker 1: doing an applex review. We did do our an applex review,
- 20:34Speaker 1: but I've been talking about some of the other practical
- 20:39Speaker 1: applications of functional medicine, and it was flipids, yes, lolowl
- 20:43Speaker 1: iming fruit.
- 20:44Speaker 2: And so the students were like, no, no, we want more.
- 20:47Speaker 2: We'll just sit here. We don't care that we're over
- 20:49Speaker 2: on time. Yeah.
- 20:49Speaker 3: I was like, okay, I can't tell you how many
- 20:52Speaker 3: students have reached out to me just to have just
- 20:55Speaker 3: a conversation with me about what I'm doing. How I
- 20:58Speaker 3: got into the space and just wanting more, wanting more
- 21:01Speaker 3: knowledge about how they can become more educated, even outside
- 21:04Speaker 3: of school necessarily. And that's kind of my next topic
- 21:07Speaker 3: I wanted to segue into is there's there's just a
- 21:10Speaker 3: growing list of different pg X certification programs, right, so
- 21:14Speaker 3: we have ones from a s HP, a c CP,
- 21:18Speaker 3: the ORX Genomics has courses, UF has the Mayo Clinic,
- 21:22Speaker 3: and with the boards. We were talking test to Learn,
- 21:27Speaker 3: Test to Learn yees.
- 21:28Speaker 2: Another one that's out There's there's quite a few.
- 21:31Speaker 4: These are just a few that I was just naming.
- 21:33Speaker 3: But we were talking about the Board of Pharmacy Specialty
- 21:36Speaker 3: Practices as well.
- 21:38Speaker 4: And and and it's being in the foresight.
- 21:40Speaker 3: I think it's I honestly think it is something that's
- 21:43Speaker 3: coming into the near and to our reality very quickly.
- 21:46Speaker 4: Here as far as becoming.
- 21:48Speaker 3: A potential, it's been put in front of that board
- 21:50Speaker 3: a few times for it to become a specialty. And
- 21:53Speaker 3: I feel like it's this year that that that may
- 21:55Speaker 3: even be on the docket for that as well. And
- 21:59Speaker 3: so I want to think about what pathway would you
- 22:02Speaker 3: recommend for pharmacists or students who want to be, you know,
- 22:06Speaker 3: become deeper in their knowledge and expertise of expertise of PGX,
- 22:11Speaker 3: especially if they're new or transitioning from other clinical areas,
- 22:15Speaker 3: so practicing pharmacists already out or student level base right,
- 22:20Speaker 3: any any insight for them?
- 22:23Speaker 1: Okay, So I will give the University of Florida College
- 22:27Speaker 1: of Firmacy Therapeutic Exams to answer, you're ready, Yes, it
- 22:31Speaker 1: depends yes.
- 22:34Speaker 2: So it truly does depend.
- 22:35Speaker 1: It depends on what the pharmacist goal is and what
- 22:40Speaker 1: they're wanting to get from the education and what they're
- 22:43Speaker 1: wanting to do with the education, right, are.
- 22:45Speaker 2: They just curious and interested? You know so? And then
- 22:49Speaker 2: also timing do they want a live.
- 22:53Speaker 1: Experience in the learning? They want a pre recorded do
- 22:57Speaker 1: they want a webinar? So these are the things that
- 23:02Speaker 1: that they have to ask themselves when they're evaluating these
- 23:04Speaker 1: different programs. I think all the programs you listed are
- 23:06Speaker 1: very good, right, I'm not familiar with the our ex
- 23:09Speaker 1: Genomics one, I'll be honest.
- 23:10Speaker 3: Yeah, our ex Genomics has a one hour free CE,
- 23:14Speaker 3: I will say for anybody to take practitioner or pharmacists
- 23:18Speaker 3: to like. And they also have an eight hour certification
- 23:21Speaker 3: just a general overview of pharmacogenomics as well, so they
- 23:24Speaker 3: it has a higher level of teaching on it, but
- 23:27Speaker 3: also a free CE.
- 23:29Speaker 4: So check that out if anybody.
- 23:31Speaker 1: It would also be careful, like, you know, so when
- 23:33Speaker 1: I first started as a pharmacist and you're doing ces
- 23:35Speaker 1: and you're getting this and you're getting that. So some
- 23:37Speaker 1: of these certifications, it's just that entity calling it a certification.
- 23:42Speaker 2: So it depends on what they're after and what they
- 23:45Speaker 2: want to do with it.
- 23:46Speaker 1: To be careful with the certifications because it's just that
- 23:49Speaker 1: entity calling it a certificate. If you want a true
- 23:52Speaker 1: board certification, that's that's through the Board of Pharmacy Specialties, right,
- 23:57Speaker 1: which is what we were talking about there. Yeah, So
- 24:01Speaker 1: so be careful with that that, you know. A.
- 24:05Speaker 3: I think we're just getting foundational knowledge more than they're
- 24:08Speaker 3: getting in school is what people are hungry for.
- 24:11Speaker 4: So I will these are multiple options.
- 24:14Speaker 1: I will put up there the University of Florida's Pharmacogenomics
- 24:19Speaker 1: UH certificate programs. They're really great if you are a
- 24:24Speaker 1: pharmacist in the state of Florida. The nice thing is
- 24:27Speaker 1: is those can count as consultant hours, so sometimes if
- 24:30Speaker 1: you have a consultant license, those are hard to find.
- 24:33Speaker 1: They do have little mini courses, but they also have
- 24:35Speaker 1: a big, long like certificate course. They are not they
- 24:40Speaker 1: are my alma mater, but they are also one of
- 24:42Speaker 1: the ogs in from a COO genomics space.
- 24:48Speaker 2: I remember the first pharmacogenomics.
- 24:50Speaker 1: Type book that ever came out was full of University
- 24:52Speaker 1: of Florida people, so that was pretty exciting for me
- 24:56Speaker 1: as an alone. But absolutely I would it.
- 25:00Speaker 3: Has the first pheno conversion calculator for two D six
- 25:03Speaker 3: as well.
- 25:04Speaker 4: Yes, so I like that one.
- 25:09Speaker 1: I would plug that one if you're asking me to
- 25:11Speaker 1: recommend one. But also, you know, look at what fits.
- 25:14Speaker 2: Your needs and your learning style.
- 25:16Speaker 1: You know, That's one thing we talk about a lot
- 25:19Speaker 1: as advisors with our students at lee com is learning style,
- 25:24Speaker 1: like when you're studying, what works best for you, And
- 25:26Speaker 1: that applies to see E's too, because see E's you're
- 25:28Speaker 1: spending money and you want to get the biggest bang
- 25:32Speaker 1: for your buck and retain that knowledge.
- 25:34Speaker 2: Personally, if I am you know, have something.
- 25:38Speaker 1: That's recorded and I'm not like engaged with live people,
- 25:41Speaker 1: sometimes I zone out and.
- 25:42Speaker 2: I have to back it up and it takes me
- 25:44Speaker 2: longer because I've zoned out. So knowing her learning style too, I.
- 25:48Speaker 3: Think that a lot of people are hungry even just
- 25:50Speaker 3: for context around people who are actually practicing in the space.
- 25:54Speaker 3: I attended Alive Forum Earl earlier this year with a
- 25:59Speaker 3: lot of the a lot of pharmacogenomic farms. This throughout
- 26:01Speaker 3: the United States and even internationally through Australia as well.
- 26:05Speaker 3: We're participating in it, and it was just more of
- 26:09Speaker 3: presenting information in a forum that allowed people the context
- 26:15Speaker 3: of how you can apply pharmacogenomics in every different facet
- 26:19Speaker 3: of practice. So when we think about those different areas,
- 26:23Speaker 3: I mean we can think about inbulatory care, hospitals, long
- 26:27Speaker 3: term care labs, and remote clinical or consulting jobs.
- 26:31Speaker 4: So from your advantage point, where do.
- 26:34Speaker 3: You see the most exciting opportunities right now in which
- 26:39Speaker 3: settings are truly embraced are really embracing pharmacogenomics in a
- 26:43Speaker 3: day to day clinical decision? I mean where I've seen it,
- 26:47Speaker 3: you know, hospital space, yes, clinics, things of that nature.
- 26:52Speaker 4: Josiah Allen is.
- 26:53Speaker 3: One within his hospital setting that implements that and also
- 26:58Speaker 3: provides that pgua I too residency program for pharmacists as well.
- 27:04Speaker 4: Let me look that up right.
- 27:05Speaker 3: Now because I'm going to give a shout out to
- 27:06Speaker 3: him because that's a big one for people to look at.
- 27:09Speaker 4: But I want to hear from you too.
- 27:11Speaker 1: So well, you know, I recently was able to talk
- 27:17Speaker 1: with some other universities recently and they they're not as
- 27:22Speaker 1: far as long as I expected.
- 27:23Speaker 2: So I think it.
- 27:24Speaker 1: Depends on the institution, It depends on the setting. But
- 27:28Speaker 1: I do think that you know, like I was talking
- 27:32Speaker 1: about how patients. You know, we have seen this uptick
- 27:35Speaker 1: of patients being dissatisfied with the current healthcare that they're offered.
- 27:41Speaker 1: So I do see like some of these you know,
- 27:46Speaker 1: one on one private pharmacists working with patients. I actually
- 27:51Speaker 1: think the community setting would be a really fun way
- 27:54Speaker 1: to do that. It's just how do you free up
- 27:57Speaker 1: some time for the pharmacist without overstressing them, because there
- 27:59Speaker 1: are are you overstressed? So that that's one area I think.
- 28:04Speaker 1: I have had a practice site a doctor's office for
- 28:07Speaker 1: the last five years, and I really think embedding a
- 28:10Speaker 1: pharmacist into every doctor's office is the true exciting answer
- 28:17Speaker 1: to a lot of healthcare related issues. I think that
- 28:23Speaker 1: they could incorporate pharmacogenomics. They could also incorporate monitoring tie
- 28:28Speaker 1: trading of drugs to optimal outcomes, catching adverse effects become
- 28:32Speaker 1: before they come serious become serious.
- 28:35Speaker 2: So I think.
- 28:36Speaker 1: Ambulatory care pharmacy is not something that really exists outside
- 28:39Speaker 1: of academia on a regular basis. I mean there are some,
- 28:43Speaker 1: but I think that is the key to improving health care,
- 28:48Speaker 1: improving outcomes, improving patient satisfaction, and also improving pharmacist satisfaction
- 28:55Speaker 1: with their day to day duties.
- 28:56Speaker 3: Yeah, just a kind of full circle moment from one
- 28:59Speaker 3: of us talking about before too.
- 29:01Speaker 4: Josiah Allen, he was out.
- 29:02Speaker 3: He's out of Saint Elizabeth Healthcare in Cincinnati, Ohio. So
- 29:06Speaker 3: that's where the PGY two Clinical Pharmacogenomics Pharmacy Residency program
- 29:12Speaker 3: is located and he's.
- 29:13Speaker 4: The director of that.
- 29:14Speaker 3: So keep keep your students in mind for that. That's
- 29:17Speaker 3: another extension of them being able to pursue it outside
- 29:20Speaker 3: of school. Also, perfecting peds. Have you ever heard of
- 29:23Speaker 3: doctor Jenna Quinn with perfecting peds. She's a very she
- 29:26Speaker 3: specializes with utilizing pharmacogenomics that in that patient population. And
- 29:32Speaker 3: so that's a whole I mean, we think about our
- 29:35Speaker 3: young population, right and and implementing it there. And there's
- 29:38Speaker 3: different ways of incorporating the pharmacogenomics specifically with kids, right
- 29:43Speaker 3: because of just the nature.
- 29:46Speaker 1: If you if you're a pharmacist out there and you're
- 29:48Speaker 1: interested in pharmacogenomics, like I mean, I literally taught myself pharmacogenomics.
- 29:53Speaker 1: I was teaching myself pharmacogenomics when farm GKV was this.
- 29:59Speaker 4: Like yes, you always tell me that it was like
- 30:03Speaker 4: hard to find get context about that.
- 30:05Speaker 3: You were you started back with your with the company
- 30:09Speaker 3: that you worked the genetics company you worked with back
- 30:11Speaker 3: in what what year was that?
- 30:12Speaker 4: I want context around this.
- 30:13Speaker 2: It was twenty four I think it was twenty fourteen.
- 30:15Speaker 4: I probably twenty fourteen between that time frame it was.
- 30:20Speaker 2: Yeah, it was kind of around there. Maybe it was
- 30:21Speaker 2: twenty twelve.
- 30:23Speaker 4: Yeah, so early was back, is it right?
- 30:25Speaker 2: Back then? H what was that?
- 30:27Speaker 4: I said, early stages.
- 30:29Speaker 1: Yeah, so you know, there there was you know, there
- 30:32Speaker 1: was some pharmacogonal mixed education in pharmacy school back then,
- 30:35Speaker 1: at least at the University of Florida Pioneer. But you know,
- 30:40Speaker 1: it really wasn't anything that was talked.
- 30:41Speaker 2: About too much.
- 30:42Speaker 1: I worked for a really great company prior to working
- 30:45Speaker 1: for the startup company, and they were doing some research
- 30:49Speaker 1: with two D six and too moxifen.
- 30:52Speaker 2: Way back then, there were because they had so much data.
- 30:54Speaker 2: I mean, we we we did like we we.
- 30:57Speaker 1: Adjudicated about eighty percent of the prescriptions, you know states,
- 31:00Speaker 1: So that was pretty.
- 31:01Speaker 3: Yeah, I guess perspective on what's being covered as far
- 31:04Speaker 3: as the cost of testing, right right.
- 31:06Speaker 1: So so yeah, so back then when I got the
- 31:12Speaker 1: connection to work for this startup company. I was like,
- 31:15Speaker 1: I need I have to learn more, and so I
- 31:18Speaker 1: just sat there and you know, absorbed everything I could.
- 31:22Speaker 2: Uh.
- 31:22Speaker 1: Farm GKB, which is its own website now, was like
- 31:26Speaker 1: a website within a website, and that's where I got.
- 31:29Speaker 2: A lot of information.
- 31:30Speaker 1: They have a YouTube channel, which is kind of cool.
- 31:32Speaker 1: They have lots of resources. If you are a teacher
- 31:35Speaker 1: like me and you need good graphics, they have beautiful
- 31:38Speaker 1: graphics for pathways. So I do recommend that website a lot.
- 31:42Speaker 1: Cpig is your other big website for fharmacogenomics. They do
- 31:47Speaker 1: put out guidelines, but the FDA does have a list
- 31:51Speaker 1: of medications that they recommend genetic considerations for a lot
- 31:58Speaker 1: of this stuff. There's not there's not a lot of
- 32:00Speaker 1: drugs that require genetic testing, but it is recommended for
- 32:05Speaker 1: more drugs than you would actually think. It's making it
- 32:08Speaker 1: into the package in sort. That is something that is
- 32:10Speaker 1: being pushed by the FDA to have that data. Be honest,
- 32:16Speaker 1: drug companies don't want to do that data because it
- 32:18Speaker 1: pigeonholes them. If you do exactly on a drug and
- 32:22Speaker 1: you find that it doesn't work great in a population.
- 32:24Speaker 1: Plavix is your best example of this, then then they
- 32:27Speaker 1: can't service a portion of pack population, and they don't
- 32:30Speaker 1: like that exactly.
- 32:32Speaker 3: However, it's more it's safe, better safety for a file
- 32:34Speaker 3: for selection for the patient.
- 32:36Speaker 4: God forbid.
- 32:38Speaker 2: They do have to do that now. So so that's
- 32:41Speaker 2: kind of you.
- 32:41Speaker 1: Know, so there are there are you know, entities out
- 32:44Speaker 1: there that are are housing this information and you can
- 32:47Speaker 1: you can learn a lot on your own without.
- 32:49Speaker 2: Even spending money on these certific certification programs.
- 32:52Speaker 3: Yeah, and quite honestly, when I went through my process
- 32:54Speaker 3: of becoming more familiarized with PGX, that was kind of
- 32:57Speaker 3: a similar journey. I did do a certification course, but
- 33:01Speaker 3: my practical knowledge came from the practical use of it.
- 33:05Speaker 3: It was actually applying it, counseling on it, and presenting
- 33:09Speaker 3: it in different forums to people so.
- 33:13Speaker 4: They would understand how important it is.
- 33:16Speaker 1: So back in twenty twelve, twenty fourteen, whenever I think
- 33:20Speaker 1: it was twenty twelve, thank you're right, twenty twelve, when
- 33:24Speaker 1: I was working for the startup company, what our product was.
- 33:26Speaker 2: Was totally different than anything else in the market.
- 33:30Speaker 1: It kind of arguably still is, and what it was
- 33:33Speaker 1: doing is it was marrying the pharmacogenomics with the medications
- 33:38Speaker 1: of the patient was actually taking. The doctor got a
- 33:41Speaker 1: real life, actionable report that was for that patient. Yes,
- 33:46Speaker 1: at the end of the day, it's not just your
- 33:49Speaker 1: pharma code, not just your genetics that are determining how
- 33:52Speaker 1: you handle drugs.
- 33:53Speaker 2: It's also the other drugs.
- 33:55Speaker 1: It's also you know, kidney liver function, nutrition status, gender
- 34:00Speaker 1: for some drugs. So you know, it was marrying all
- 34:03Speaker 1: that together and putting it in a piece of paper
- 34:07Speaker 1: for the position to know what that was very time consuming.
- 34:12Speaker 2: We did those reports in Excel, so that was that.
- 34:15Speaker 3: Was the Now automation and AI have come into the
- 34:19Speaker 3: picture with all that, so it has definitely that there
- 34:22Speaker 3: you go with the more less burden but more clinical.
- 34:26Speaker 4: We can look at the information as opposed to creating
- 34:28Speaker 4: the wheel.
- 34:29Speaker 2: Right if pharmacist, if pharmacists had gotten.
- 34:33Speaker 1: Reimbursed for our time in creating those reports like directly
- 34:37Speaker 1: like we like, we probably still would be doing that,
- 34:41Speaker 1: And I think that's better, Like, yes, we can automate this,
- 34:44Speaker 1: but for cost savings. But you know, sometimes you have
- 34:48Speaker 1: to ask us that the right thing to do and
- 34:49Speaker 1: and so sometimes I wonder is that the right thing
- 34:52Speaker 1: to do?
- 34:52Speaker 2: And I do think I do think it's helpful. But
- 34:55Speaker 2: I do think having this special sauce of a pharmacist.
- 34:58Speaker 4: Oh yes, the oversight has to be there.
- 35:01Speaker 1: Yeah, And even talking to a physician or talking to
- 35:04Speaker 1: a patient.
- 35:04Speaker 3: Oh no, I think yes, they don't want to just
- 35:07Speaker 3: have something regurgitated to them from some automated PDF and
- 35:12Speaker 3: a lot of times when they're even reading it, they
- 35:14Speaker 3: don't even know interpreting it and understanding it is just
- 35:18Speaker 3: not translating. So when they can, and patients would rather
- 35:22Speaker 3: be speaking to a pharmacist in general, and physicians are
- 35:25Speaker 3: now becoming a lot more welcoming of that because now
- 35:29Speaker 3: that it's being asked of them to be ordering from
- 35:32Speaker 3: their patients more often and they're getting in these I
- 35:35Speaker 3: find more often than not it's a patient being having
- 35:38Speaker 3: the barrier of the provider not feeling comfortable with ordering
- 35:41Speaker 3: and then having to find it through different types of
- 35:44Speaker 3: labs that will provide it to them.
- 35:47Speaker 4: And yes, it's a big barrier for them, for sure.
- 35:51Speaker 2: It's a lot.
- 35:52Speaker 4: There's a lot to bite off here, Definitely.
- 35:55Speaker 1: I just think I still think though that that pharmacists,
- 35:59Speaker 1: you know, however you slice that, I do think in
- 36:01Speaker 1: order for us to take the next step in providing
- 36:04Speaker 1: patients better healthcare. I do think pharmacists just need to
- 36:07Speaker 1: be paid for their time and their clinical expertise.
- 36:10Speaker 4: I can't agree with you more. I can't agree with
- 36:13Speaker 4: you more.
- 36:14Speaker 3: That is something that I've been working towards for many years,
- 36:17Speaker 3: now you more than me, but definitely many years in
- 36:20Speaker 3: the working.
- 36:21Speaker 4: It'll it's coming.
- 36:22Speaker 3: I see it on the horizon for us, coming on
- 36:25Speaker 3: sooner than later in my opinion.
- 36:27Speaker 4: But I want to first of all thank you for
- 36:30Speaker 4: being on this episode with me today.
- 36:32Speaker 3: You've brought such great insight into the space of academia
- 36:38Speaker 3: where pharmacogenomics is how you're providing that to your students
- 36:41Speaker 3: that currently go to LEECOM. We've talked about many different
- 36:44Speaker 3: facets of how it can be incorporated and next steps
- 36:47Speaker 3: for anybody.
- 36:48Speaker 4: Who may be interested in pursuing it as well.
- 36:51Speaker 3: So I want to just conclude with that's bringing us
- 36:54Speaker 3: to the end of today's episode. I want to thank
- 36:56Speaker 3: Vanessa for being on the episode today. You have been
- 36:59Speaker 3: a huge asset and bringing forth knowledge about where how
- 37:02Speaker 3: PGX is being implemented into the academic space for pharmacy students,
- 37:06Speaker 3: and I just wanted to thank you for being here.
- 37:09Speaker 1: Thank you so much for having me. It was lovely
- 37:11Speaker 1: to get a chance to talk about this. I'm passionate
- 37:13Speaker 1: about pharmacogenomics. I'm passionate about.
- 37:15Speaker 2: Taking pharmacy to the next level. So thanks for having me.
- 37:18Speaker 3: Oh, You're so welcome. I'm so glad you were able
- 37:20Speaker 3: to be here and to our listeners. If you're inspired
- 37:23Speaker 3: by today's discussions, check out are my shows notes actually
- 37:28Speaker 3: for links for these PGX training programs and certification opportunities.
- 37:33Speaker 3: I wanted to leave those there for anybody interested in
- 37:36Speaker 3: furthering their education and pharmacogenomics and being able to start
- 37:39Speaker 3: implementing with your own patient populations. So until next time,
- 37:44Speaker 3: I'm doctor Melissa Smith. Thanks for tuning in to the
- 37:46Speaker 3: Precision Medicine Pharmacist on the Pharmacist Podcast Network. Stay curious,
- 37:51Speaker 3: stay innovative, and always be precise. Wh