Latest / Stuff You Should Know / How Migraines Work
Transcript
- 0:00Speaker 1: Brought to you by the reinvented two thousand twelve camera.
- 0:03Speaker 1: It's ready. Are you welcome to stuff you should know
- 0:08Speaker 1: from house toff works dot com? Hey, and welcome to
- 0:16Speaker 1: the podcast on Josh Clark with Me. Is always this
- 0:19Speaker 1: Charles Chuck Bryant suffering from what looks like a headache.
- 0:24Speaker 1: And I just did that. Okay, that was method podcasting
- 0:28Speaker 1: and I was falling for it on a purpose. So
- 0:32Speaker 1: what's your witty intro? Because this is a fan request?
- 0:37Speaker 1: Is this super fan buddies? Yeah? Cooper Chuck? Oh was it? Yeah?
- 0:41Speaker 1: Does he have migraines? Cooper? Uh? Well, we'll say his name,
- 0:44Speaker 1: Aaron Cooper. He didn't mind. He's all over the place.
- 0:46Speaker 1: He uh has been asking for this podcast for a
- 0:49Speaker 1: couple of years and I finally wrote him to day.
- 0:52Speaker 1: I was like, Merry Christmas, jerk. Yeah, can you imagine
- 0:56Speaker 1: having a migraine that's bad enough? Having a migraine in
- 1:00Speaker 1: Kansas is like a million times words and having to
- 1:04Speaker 1: listen to us make fun of it. Uh, Aaron requested this,
- 1:08Speaker 1: and we I just want to go ahead and say
- 1:09Speaker 1: Aaron has the RS, which we'll get to. He has
- 1:13Speaker 1: alternating sides that they occur on sounds pretty been having
- 1:18Speaker 1: since he was a kid, and he has his triggers
- 1:22Speaker 1: food based sometimes sugar, caffeine, water, and now, and he
- 1:26Speaker 1: has his treatment now, which is when he sees the aura,
- 1:30Speaker 1: he knows it's coming too ecceteran migraines, dark room and
- 1:36Speaker 1: water and nap for like an hour and a half.
- 1:38Speaker 1: And he says he's gotten way better at staving them off.
- 1:41Speaker 1: So that's Kopa said it would feature you, so they're
- 1:45Speaker 1: not give me my money. There's the introduction. Is it really? Oh,
- 1:49Speaker 1: I'm glad you did that because I had none? Okay, great, Yeah,
- 1:53Speaker 1: welcome to the podcast. So Chuck, yes, uh, well, let's
- 1:59Speaker 1: talk about my brains. It sounds like, from what you
- 2:01Speaker 1: just described, Cooper is sadly um a pretty typical migraine
- 2:07Speaker 1: stuffer in that you have to really pay attention to
- 2:09Speaker 1: it yourself, figure out what works for you, what triggers it,
- 2:12Speaker 1: and when it's coming, and basically treat yourself because doctors
- 2:18Speaker 1: don't really have much of an idea of what migraines are. Um,
- 2:22Speaker 1: we know that they're not headaches because headaches are caused
- 2:25Speaker 1: by vaso constriction in the brain tightening of blood vessels, right,
- 2:30Speaker 1: that is right. Just Uh, they used to think that
- 2:33Speaker 1: migraines were caused by vaso dilation, just the opening of
- 2:37Speaker 1: blood vessels in the brain. That's still a common factor
- 2:42Speaker 1: in migraines. But that's not the only peace to the puzzle, right, Um,
- 2:47Speaker 1: Like you said, my migraines typically focus on one side
- 2:51Speaker 1: or the other. Um, they seem to be passed down
- 2:55Speaker 1: among families. Yeah, you're I think if one of your
- 2:59Speaker 1: parents had had my brains, you're about fifty more likely,
- 3:02Speaker 1: and if both of your parents had them, you're seventy
- 3:04Speaker 1: percent more likely. Now you were sevent in trouble. Yeah, yeah,
- 3:09Speaker 1: your parents. Have you ever had one? No, you don't
- 3:13Speaker 1: get them. No, And I seem to remember my mom
- 3:15Speaker 1: or my dad saying that they had them. But it
- 3:20Speaker 1: may have been a cluster headache. We'll get to those later.
- 3:22Speaker 1: There's there was ten times likelier that it was your
- 3:25Speaker 1: dad that said that. Then, because menton has more likely
- 3:28Speaker 1: to get cluster heady. But women are more likely to
- 3:31Speaker 1: get migraines, right, Like, Uh, eight percent of women get
- 3:34Speaker 1: migraines and six percent of men. That would make women
- 3:37Speaker 1: three times more likely. Yeah, that's in America, at least
- 3:40Speaker 1: twelve to twenty four Americans have migraines million. Right, there's
- 3:45Speaker 1: a hundred homeless people worldwide, so they can and this
- 3:50Speaker 1: this is the general overview. They can last anywhere from
- 3:52Speaker 1: a few minutes to the some reports of years without stop,
- 3:58Speaker 1: which can you imagine, now, why would you be alive still? Yeah, exactly,
- 4:02Speaker 1: Like I can't imagine that even an hour, it would
- 4:07Speaker 1: be horrible, but years, days, months, it's horrible. I don't
- 4:11Speaker 1: get headaches much at all, but when I do, I'm
- 4:13Speaker 1: not a happy camper. Loss of vision, vomiting tremors, stroke
- 4:17Speaker 1: like symptoms. These are what migraines can do to you, right,
- 4:20Speaker 1: and um that you hit upon something with that last one,
- 4:23Speaker 1: the stroke conditions or stroke symptoms. UM. The the migraine
- 4:28Speaker 1: has been kind of it's been taken out of the
- 4:30Speaker 1: realm of headaches and has recently been reclassified as a
- 4:33Speaker 1: neurobiological condition. And UM the stroke symptoms you talked about
- 4:38Speaker 1: some some migraines, some type of migraine. UM see sufferers
- 4:44Speaker 1: suffer from UM these stroke like symptoms, like they have
- 4:48Speaker 1: cognitive impairment, like they can't recognize words all of a
- 4:51Speaker 1: sudden like their armigo numb yeah. Um, they can't talk
- 4:55Speaker 1: correctly and when that happens, there's a migraine that coming. Right. Yeah,
- 5:01Speaker 1: there's are set up. Oh. Also triggers. That's a big
- 5:05Speaker 1: one too. Yeah, that's there's there's always a trigger and
- 5:09Speaker 1: they can we'll talk about the triggers in detail, but
- 5:11Speaker 1: they can vary. It's all according to the person. They're
- 5:14Speaker 1: different for everybody. Right, So here's what we know so
- 5:17Speaker 1: far as going on in the brain. Right, Um, there's
- 5:21Speaker 1: some sort of trigger, right, and we'll talk about triggers.
- 5:23Speaker 1: But let's say you, um the example used as you
- 5:28Speaker 1: didn't eat like you normally do. Yeah, you didn't get
- 5:31Speaker 1: out for lunch at noon, um, and something in that
- 5:36Speaker 1: lack of routine or changing routine sets off the NO
- 5:39Speaker 1: susceptors in the brain pain receptors the remember yeah, um.
- 5:46Speaker 1: The NO susceptors release chemicals called neuropeptides, and neuropeptides are
- 5:51Speaker 1: unique their neurotransmitters, which means that this is how one
- 5:56Speaker 1: neuron communicates with another. They create the electrochemical imp that
- 6:00Speaker 1: creates the language of the brain. Right, you know a
- 6:02Speaker 1: lot about the stuff now I do well. Version in
- 6:04Speaker 1: the brain, my friend. Yeah. But the and this is
- 6:07Speaker 1: where it relates to migraines. Neuropeptides, these proteins UM can
- 6:12Speaker 1: be a neurotransmitter or they could be a neuromodulator, and
- 6:16Speaker 1: a neuromodulator can turn the volume up or down on
- 6:19Speaker 1: the transmission of other neurotransmitters. Right. In this case, these
- 6:23Speaker 1: neuropeptides turn the volume way up on the pain receptors
- 6:28Speaker 1: in the brain, and so all of a sudden you
- 6:31Speaker 1: start to experience a headache like you've never had before
- 6:33Speaker 1: in your entire life. Yeah. Basically makes these pain sensing
- 6:37Speaker 1: cells way more sensitive than they ever would have been, right. Um.
- 6:41Speaker 1: The the neuropeptides also, for some reason relax blood vessels
- 6:46Speaker 1: in the brain, which causes the vasidilation. Um. But they
- 6:49Speaker 1: also think that this is what causes the auras. Yeah,
- 6:53Speaker 1: now the auras. We I don't think we saw what
- 6:54Speaker 1: that is. It's like a sort of a hallucinogenic visual
- 6:59Speaker 1: thing that happens. Um lights lines blurry things, and they
- 7:04Speaker 1: will or tunnel visions and they will proceed. It's a
- 7:09Speaker 1: warning sign like migraines are coming. Maybe thirty minutes maybe
- 7:12Speaker 1: and a day, but it's a coming. So that's what
- 7:15Speaker 1: ours are, right, Um. And they think that that comes
- 7:19Speaker 1: from this vasidilation in the brain, Like basically you're your
- 7:23Speaker 1: brains just doing something screwy because all of a sudden
- 7:26Speaker 1: there's a lot more blood flow and it maybe somebody's
- 7:29Speaker 1: getting pressed on, somebody's getting a lot more oxygen's overworking.
- 7:32Speaker 1: Who knows. Well. They can also cause leakage, actual leakage,
- 7:35Speaker 1: right eventually they and that makes the tissue around the
- 7:40Speaker 1: brain swell in your skull. So you have a lot
- 7:44Speaker 1: more oxygen, you have leaking blood vessels, you have these auras,
- 7:49Speaker 1: and you have in this cascade of heightened pain reception
- 7:55Speaker 1: in the brain, and there is your migraine. As far
- 7:58Speaker 1: as we understand it now, this is the most recent
- 8:01Speaker 1: thinking of what migraines are. And some guy just told
- 8:04Speaker 1: us this like thirty minutes thirty minutes ago. Hot off
- 8:07Speaker 1: the presses. Uh. And since we mentioned triggers, we should
- 8:11Speaker 1: talk about those for a second. They can depend on Uh.
- 8:15Speaker 1: It's that they're not even the same for everyone. As
- 8:17Speaker 1: Coup pointed out, they can be different things for him,
- 8:19Speaker 1: like sometimes he said, caffeine will trigger it. Sometimes a
- 8:22Speaker 1: lack of caffeine will trigger it. Right, It seems like
- 8:25Speaker 1: the one constant in migraines is that they are they
- 8:29Speaker 1: are triggered by change. Yeah, yeah, yeah, true, Yeah, that's
- 8:34Speaker 1: really good things. Um so like food related um some
- 8:38Speaker 1: say that caffeine, alcohol, cheese, gluten, nuts, soy msg. They
- 8:45Speaker 1: can be triggers. Um smells, strong smells, strong smells like
- 8:49Speaker 1: skraut onions, cologne. You got an elevator with somebody with
- 8:53Speaker 1: really heavy perfume, you might get off the water with
- 8:55Speaker 1: an aura happening. Yeah, and you're gonna be like, curse
- 8:58Speaker 1: you snoop dog. Right. They can be behavioral, like we said,
- 9:04Speaker 1: if you don't get enough sleep, or if you didn't
- 9:06Speaker 1: eat on time, or if you're stressed, or maybe you
- 9:09Speaker 1: just had sex or you're not having sex. Not having sex. Second,
- 9:13Speaker 1: that's a real bummer. Um. Exercise, you exercise too hard
- 9:17Speaker 1: or you don't exercise enough. So it's it's you never
- 9:21Speaker 1: can't tell. That's what makes migraines such jerks. No, and
- 9:24Speaker 1: this is we should say, like all of these are
- 9:26Speaker 1: are like the characteristics the symptoms of all of the
- 9:31Speaker 1: migraine sufferers in the world. Sure, for one person it
- 9:34Speaker 1: might be Uh, they might be Uh no sex anchovy,
- 9:39Speaker 1: um catheine just suffer. That's my Friday night dude. Right.
- 9:46Speaker 1: There's also hormones. Yeah, and that's why they think that women,
- 9:50Speaker 1: um might have more than men because of hormonal changes
- 9:53Speaker 1: that women experience that men do not. And there's a
- 9:56Speaker 1: lot of correlative evidence among up that implicate hormones in
- 10:01Speaker 1: in in migraines like UM, migraines typically start after puberty
- 10:06Speaker 1: and women right when the hormones really start kicking in
- 10:10Speaker 1: UM they are very very rare. And women after menopause,
- 10:14Speaker 1: when hormones are depleted, they actually can come about again
- 10:18Speaker 1: in post mental puzzle women with hormone replacement therapy, UM,
- 10:23Speaker 1: they can correlate with menstruation and and uh, when a
- 10:28Speaker 1: woman becomes pregnant, has been pregnant, Uh, the migraines often
- 10:34Speaker 1: subside or just go away completely. Right. So there's something
- 10:36Speaker 1: to that. Oh yeah, there's a lot to it. The
- 10:38Speaker 1: sad thing is that we have no idea what it is.
- 10:41Speaker 1: You know, there's some poor schemo out there having a
- 10:43Speaker 1: migraine right now and there's nothing anybody can do to
- 10:48Speaker 1: help him right now. Well, maybe they're the dulcet tones
- 10:50Speaker 1: of Josh Clark and his earbuds will make that go away?
- 10:54Speaker 1: You think maybe because there are environmental factors that can
- 10:58Speaker 1: make them happen, so maybe they can make them go away.
- 11:00Speaker 1: I think that the dulcet tones of my voice was
- 11:03Speaker 1: the cause of migraine, like a flashing light like remember
- 11:06Speaker 1: the Nissan pulsar. Do you remember the break light went
- 11:10Speaker 1: They actually had to slow the pattern because people were
- 11:13Speaker 1: having seizures. Apparently that is probably an urban legend, but
- 11:17Speaker 1: it's a good one that I remember from the eighties.
- 11:20Speaker 1: That sounds very much like an urban legend. Loud noises, um,
- 11:23Speaker 1: strong smells, like we said, weather pattern like rain, yeah, um,
- 11:29Speaker 1: either when it's about to come on or it's just
- 11:32Speaker 1: changed subsided, especially when it happens quickly e g. The summer,
- 11:37Speaker 1: the change in barometric pressure. I suspect has a lot
- 11:39Speaker 1: to do with that. Josh, what are the types of migraines? Well, Chuck,
- 11:43Speaker 1: there is the classic migraine. We're gonna start with the second. First,
- 11:48Speaker 1: there's the classic migraine that is preceded by an aura
- 11:52Speaker 1: of some sort. The head pain comes on and uh,
- 11:57Speaker 1: you're in big trouble. Right. There also chronic migraines, which
- 12:01Speaker 1: are arguably among the worst, be more than fifteen a month. Yeah,
- 12:06Speaker 1: that's basically a lot of classic a lot of classic migraines, right, um,
- 12:12Speaker 1: common migraines. This is migraine pain with no aura. Yeah,
- 12:16Speaker 1: no aura. Yeah, it's this is like a burger king
- 12:19Speaker 1: of of horrible headaches, isn't it? Like however you want it? Yeah,
- 12:24Speaker 1: but they did say that the common migraine though, while
- 12:27Speaker 1: you may not have an aura, there might be feelings
- 12:30Speaker 1: of euphoria or cognitive problems signaling like here it's a coming, right,
- 12:35Speaker 1: which is so depressing if you think about it, like, man,
- 12:37Speaker 1: I feel great and then you think crap. Uh. There
- 12:44Speaker 1: are or I'm sorry, ocular migraines, which you get our
- 12:49Speaker 1: symptoms without the pain of the headache, and they can
- 12:54Speaker 1: just be like thirty minutes and they go away. So
- 12:57Speaker 1: I don't understand if there's no pain and involved, and
- 13:01Speaker 1: all you're getting is the hallucinogenic aura symptoms like what's
- 13:05Speaker 1: the rub I mean imagine is distracting, but right, and
- 13:10Speaker 1: this is probably a little concerning, like you're like, am
- 13:12Speaker 1: I losing my mind? I have a brain tumor It's true.
- 13:16Speaker 1: I'd like to hear from someone that suffers from ocular migraines. Actually,
- 13:19Speaker 1: I wanted a better understanding of that firsthand. Abdominal migraines
- 13:22Speaker 1: common in children, pretty awful. It's like all of the
- 13:25Speaker 1: symptoms of a migraine except for the head pain. So
- 13:29Speaker 1: you have sensitivity, a light nausea, vomiting um, screeching at
- 13:34Speaker 1: anybody who tries to talk to you, that kind of thing,
- 13:36Speaker 1: you know. The other thing Coop said is that he
- 13:39Speaker 1: very much used to experience while he still experiences the nausea,
- 13:43Speaker 1: but he said that he has gained such control over
- 13:45Speaker 1: his vomit reflex that he has not thrown up since
- 13:49Speaker 1: nine since Ghostbusters. He said, wow. Yeah, any also reference Seinfeld,
- 13:55Speaker 1: of course, because I was gonna say that black and
- 13:57Speaker 1: white cookie. That's right. H. Then there are cluster headaches,
- 14:00Speaker 1: which we mentioned that men get more often, and they
- 14:03Speaker 1: are not migraines, but they say they may be the
- 14:06Speaker 1: most painful headache of all. But you remember and Donnie Darko,
- 14:09Speaker 1: where Drew Barrymore tells everybody. There's some linguists who said
- 14:12Speaker 1: that cellar door is the most beautiful phrase in the
- 14:15Speaker 1: English language. Cluster headaches. Those two words they evoke. Do
- 14:20Speaker 1: you know what a grape shot cannonball is? What it
- 14:24Speaker 1: looks like. Okay, so I see one of those, But
- 14:27Speaker 1: they're white and squishy balls that are connected together, almost
- 14:32Speaker 1: like tumors, but they're real circular. They're spherical, right, and
- 14:38Speaker 1: they start to like kind of drip and fall off,
- 14:40Speaker 1: but they're constantly replaced. That's what comes into my mind's
- 14:43Speaker 1: eye when I hear the word, the term cluster headache. Well,
- 14:47Speaker 1: it sounds like it's that bad because it's a sudden
- 14:49Speaker 1: explosion of pain after you've gone to sleep, Like you'll
- 14:54Speaker 1: be asleep and you'll wake up with this happening very quickly,
- 14:57Speaker 1: and it's usually behind one of your eyeballs. I think
- 15:00Speaker 1: that's what my dad used to have, because he used
- 15:01Speaker 1: to talk about it's right here and he pointed his
- 15:04Speaker 1: eye and I would just laugh and say, Dad, you're
- 15:07Speaker 1: so funny. So I'm getting that only in one way
- 15:13Speaker 1: or another. The reason they call him cluster heaches is
- 15:15Speaker 1: because they occur a bunch of times over the course
- 15:19Speaker 1: of a couple of weeks. Then they'll go away, like
- 15:21Speaker 1: for a year maybe then they'll come back in clusters
- 15:25Speaker 1: in clusters over several weeks or whatever, and then go
- 15:28Speaker 1: ahead with a thunderclap headache because I've never heard of that.
- 15:31Speaker 1: Thunderclap headaches are um, very sudden, very severe. They're pretty
- 15:37Speaker 1: much cluster headache, except they don't follow the same pattern.
- 15:41Speaker 1: They just kind of come and go. They don't seem
- 15:43Speaker 1: to follow any kind of pattern really, and it's like
- 15:45Speaker 1: they're shorter. But um, if you get thunderclap headache, you
- 15:50Speaker 1: may have blood pooling in your brain and you need
- 15:52Speaker 1: to go see a doctor. Yeah, that's it's a pretty
- 15:54Speaker 1: good sign that there's something very wrong with your brain. Um,
- 15:57Speaker 1: And we should say cluster headaches and thunderclap headaches don't
- 16:01Speaker 1: tend to occurrent families, whereas my graines to look at you,
- 16:07Speaker 1: So how do you know? How do you get diagnosed
- 16:10Speaker 1: with this? Basically you go in and say I think
- 16:13Speaker 1: I have a brain tumor, and the doctor starts running
- 16:16Speaker 1: tests on you using m ryes, cat scans, spinal taps,
- 16:21Speaker 1: rule everything else. Everything else is ruled out, and they go,
- 16:24Speaker 1: I think you might have migraines. But since we can't
- 16:27Speaker 1: really explain migraines, well, I can't say for certain spinal tap.
- 16:31Speaker 1: You ever had one of this? No, well, there's no
- 16:34Speaker 1: reason that you should have, have you No, of course
- 16:37Speaker 1: not well not, of course not people have them. But
- 16:40Speaker 1: I just you know, you always laugh at spinal tap
- 16:42Speaker 1: because the band and the movie, but you don't think
- 16:45Speaker 1: about a needle going into your spine. That's what they're doing.
- 16:48Speaker 1: They're tapping your spine like you tap a maple tree
- 16:50Speaker 1: for syrup. And it's a big it's a big, long,
- 16:54Speaker 1: like pretty heavy gauge. It's not like a tiny one.
- 16:57Speaker 1: It's big. I'd need more than a local anist at
- 17:00Speaker 1: it for that. My friend knock me out completely. I
- 17:04Speaker 1: don't know that they can because they probably have to
- 17:06Speaker 1: be um cognizant and aware and in control of your
- 17:12Speaker 1: body so you don't move no, thank you. Uh. Some
- 17:17Speaker 1: weird symptoms we talked about nausea and vomiting and stuff
- 17:21Speaker 1: like that. You can also fart a lot. I've saw
- 17:26Speaker 1: that flatulence problem. Flatulence a lot. You can be really thirsty,
- 17:32Speaker 1: you can smell weird things that aren't there. You can
- 17:36Speaker 1: think that you're appendages have grown in size, like my
- 17:42Speaker 1: arm has grown. If they actually have, it's probably just overeating.
- 17:46Speaker 1: If your arm gross. If your appendages grow in size,
- 17:50Speaker 1: food cravings, temporary blindness, no fun. This is what Coop
- 17:55Speaker 1: suffers from. And he still takes the time to do
- 17:58Speaker 1: all those photoshop drops of us because he did a
- 18:03Speaker 1: really good job with the Stepbrothers one. I mean, did
- 18:06Speaker 1: you look at the detail in it? And they're all
- 18:07Speaker 1: really good and so that was the peak. Yeah, so
- 18:12Speaker 1: you got a migraine, Josh, what do you do well again?
- 18:17Speaker 1: People people seem to treat themselves, or tend to treat themselves.
- 18:21Speaker 1: They figure out what their triggers are, so they become
- 18:24Speaker 1: very aware. If you're a um, chocolate sitar, uh, you
- 18:33Speaker 1: shouldn't exercise, right. If that's you, that's my Friday night,
- 18:38Speaker 1: you're gonna you're gonna stay away from exercise. You're going
- 18:41Speaker 1: to stay away from sitar music, and you're gonna not
- 18:44Speaker 1: eat chocolate, which sucks, but that's what you're gonna do.
- 18:47Speaker 1: And so you're going to prevent it. Right, there's a
- 18:50Speaker 1: cute treatment. There's preventative treatment. So you can prevent it,
- 18:53Speaker 1: um by paying attention to what triggers. These things, paying
- 18:58Speaker 1: attention to like if you get an aura, yeah, then
- 19:03Speaker 1: you're acute. Treatment kicks in, maybe you are going to
- 19:07Speaker 1: treat yourself acutely even before an ora kicks in. If
- 19:11Speaker 1: if you expose yourself to one year triggers um and
- 19:14Speaker 1: then if you if you do get the idea that
- 19:16Speaker 1: you're going to have a migraine, you can often treat them.
- 19:19Speaker 1: Like Coupe said, with you know a couple of eccrin migraines,
- 19:23Speaker 1: which are really just um insides. Yeah, taylan a advilt
- 19:28Speaker 1: non steroidal anti inflammatory drugs, right, and that's going to
- 19:31Speaker 1: keep your brain from vasodilating supposedly. Yeah, and with ecceterrin,
- 19:36Speaker 1: we should say that they specifically made the migraine UH
- 19:40Speaker 1: pill and it's a combination of aspirin, ACTA, menefin, and caffeine,
- 19:46Speaker 1: which migraine people said that works for me. You take
- 19:52Speaker 1: these before head pain comes on. Once your head pain
- 19:55Speaker 1: comes on, you need something stronger called SUMA trip hand
- 20:01Speaker 1: summetric TAN, which is also called immatrix. Remember the immatrics
- 20:05Speaker 1: adds with the semi coming at you. Yeah, yeah, right,
- 20:08Speaker 1: Well apparently this stuff works after your head has started exploding. Yeah,
- 20:15Speaker 1: it works pretty well from what most people say, right right. Um.
- 20:18Speaker 1: I think also it's one of those things where there
- 20:21Speaker 1: works for you or it doesn't. I guess if it
- 20:23Speaker 1: works really well, you're gonna go all over the internet.
- 20:25Speaker 1: Sound great, it is right, um, but I think it
- 20:27Speaker 1: cannot work in people. But if you have nausea, if
- 20:30Speaker 1: you have vomiting, fortunately for you there is uh summetrip
- 20:34Speaker 1: tan I hope that's how you say it, um nasal sprays. Yeah,
- 20:39Speaker 1: so you can't puke that back up. There's also injections.
- 20:42Speaker 1: If you go at the hospital with the migraine, they're
- 20:44Speaker 1: probably going to give you an injection of that. But
- 20:46Speaker 1: as the author says in this article, you can get
- 20:49Speaker 1: your very own immatrix injection. Yeah, preventative. They found that. Uh,
- 20:57Speaker 1: and this is always so weird with me. For prescription drugs,
- 21:00Speaker 1: they find the off label use. They're like, well, your
- 21:03Speaker 1: blood pressure meds are stopping your migraines. That's cool. And
- 21:07Speaker 1: there's a whole host of these antidepressants. Uh, Like I said,
- 21:11Speaker 1: blood pressure medication, anihistamine, supro heptidine, cholesterol drugs, cardiovascular calcium
- 21:19Speaker 1: channel blockers. They can all help with migraines with channel blockers.
- 21:22Speaker 1: I wonder if that has to do with this, if
- 21:24Speaker 1: it slows down the transmission of neurotransmitters because they go
- 21:29Speaker 1: through ion channels. That's where the actual molecules go through. UM,
- 21:34Speaker 1: So I wonder if that has something to do with it.
- 21:36Speaker 1: And then obviously with like a blood pressure medicine that's
- 21:39Speaker 1: going to keep vasodilation from occurring. UM. And then serotonin,
- 21:44Speaker 1: they figured out that, like you said, antidepressants and other
- 21:47Speaker 1: drugs that act on serotonin regulation or production have been
- 21:52Speaker 1: shown to alleviate migraines or keep migraines from coming up
- 21:56Speaker 1: on right, So serotonin has something to do with Sarah
- 21:59Speaker 1: to owning hormones, anchovies, the crazy botox supposedly, Well, they
- 22:08Speaker 1: just found that one of the weird side effects reported
- 22:11Speaker 1: was that a fewer migraines and fewer headaches. But no
- 22:14Speaker 1: one should go and get botox to relieve their migraines.
- 22:17Speaker 1: We're not saying that. It's just we call that a sidebar,
- 22:22Speaker 1: we do. Uh. And what about what Emily likes to
- 22:26Speaker 1: call hokey pokey treatments and what other people call alternative medicine. Well,
- 22:32Speaker 1: the one that jumped out at me is butter burr. Yeah,
- 22:35Speaker 1: I've never heard of that. I hadn't either, but it's
- 22:37Speaker 1: an herbal supplement. The problem is is um it may
- 22:40Speaker 1: contain cancer causing compounds. So it's like, no, we're migraines
- 22:45Speaker 1: or early death from cancer. I don't know, Rye Bo Flavian,
- 22:50Speaker 1: eat your broccoli. Co enzyme Q tin supplements, cocute tin.
- 22:55Speaker 1: Oh you know about cocute tin? Sure? Uh, fever few.
- 22:59Speaker 1: It's an herbal supplement that apparently helps. It's an anti inflammatory.
- 23:04Speaker 1: And then there are different things you can do like massage,
- 23:09Speaker 1: breathing techniques, yoga, acupuncture has been said to help some folks.
- 23:13Speaker 1: If you're into this alternative thing, I think whatever helps
- 23:16Speaker 1: you know, well, Chuck, let's finish this. Let's bring this
- 23:20Speaker 1: migraine to an in with famous people. Yeah. So apparently
- 23:23Speaker 1: there is a theory of the migraine personality that people
- 23:27Speaker 1: who have migraines are more driven, more creative. And then
- 23:31Speaker 1: there's a lot of people who are driven in creative
- 23:34Speaker 1: or were who had migraines, like we're before migraines killed them,
- 23:39Speaker 1: right exactly, Virginia Wolf, Cervantes, uh, Nietzsche, Elvis, Freud, Monet,
- 23:47Speaker 1: BEng It's also possible that all these people just happen
- 23:50Speaker 1: to have migraines and we're creative famous, and there really
- 23:54Speaker 1: isn't a migraine personality. You know. Percy Harvin, some Minnesota
- 24:00Speaker 1: Vikings receiver played for the Florida Gators. Yeah, I was
- 24:03Speaker 1: like to have a visceral reaction to that. Yeah, he's
- 24:07Speaker 1: a migraine sufferer and he'll u I mean, it keeps
- 24:09Speaker 1: him out of practice, out of games. He has to
- 24:11Speaker 1: go basically home and seclude himself in a dark room.
- 24:14Speaker 1: Apparently they're really really bad, despite the effect he played
- 24:18Speaker 1: for Florida. I don't want to I don't want to
- 24:20Speaker 1: wish that on anybody. Maybe Tim Tebow, maybe who's this
- 24:24Speaker 1: Auburn coach? Yeah, yeah, what about him? Let's wish some
- 24:31Speaker 1: migraines on them. You got anything else, I'm done, so KOPA.
- 24:37Speaker 1: I hope buddy, you have a good Christmas and that
- 24:39Speaker 1: your migraines. I hope we enlightened you some. He's probably like, no, yeah,
- 24:44Speaker 1: I don't even know all this. Yeah, thanks, anyway, this
- 24:46Speaker 1: would have been waiting two years for what how about this?
- 24:48Speaker 1: Let's wish let's everybody just go and wish that the
- 24:52Speaker 1: scientists will hurry up and cure migraines. Come about that.
- 24:57Speaker 1: Do you want to learn more about migraines and see
- 24:59Speaker 1: a picture of a brain getting hit by lightning? You
- 25:03Speaker 1: can type that word in, Oh, we didn't talk about
- 25:06Speaker 1: the word migraine, Chuck. The etymology of the word migraine,
- 25:09Speaker 1: I should say, uh, comes from two words hem acrania
- 25:14Speaker 1: half a brain, remember it only hits part of your
- 25:17Speaker 1: brain at once, and another word megram, which is actually
- 25:21Speaker 1: now another word for migraine, but megrim back in the
- 25:24Speaker 1: eighteenth century meant basically a low feeling on a whim,
- 25:29Speaker 1: or what a delicate woman would experience, you know, when
- 25:32Speaker 1: she You know how women used to feign, or they
- 25:34Speaker 1: think women feigned a lot or whatever. This was associated
- 25:38Speaker 1: with the migraines were associated with women. Ah, So megram,
- 25:45Speaker 1: hem acrania, migraine got you. Do you want to learn
- 25:49Speaker 1: more about migraines and hem acrania and megrims and type
- 25:56Speaker 1: in either seagrams or migraine in the search bar at
- 26:01Speaker 1: how stuff works dot com and that should bring up
- 26:03Speaker 1: something interesting. You should since I said hendy, search parts
- 26:06Speaker 1: time for a listener. Mail Josh, this is about first kisses.
- 26:10Speaker 1: We got a lot of great emails. I'm going to
- 26:12Speaker 1: read one of them now, um, because this is a
- 26:15Speaker 1: nice message attached. Hi guys, including Jerry, I just listen
- 26:19Speaker 1: to your podcast I'm Kissing and made me think about
- 26:21Speaker 1: my first kiss. I'm twenty seven years old and my
- 26:23Speaker 1: first kiss happened but two years ago. When I was
- 26:28Speaker 1: growing up, I never dated and sadly not by my
- 26:30Speaker 1: own choosing. I would admire the popular boys from Afar
- 26:33Speaker 1: and imagine what it would be like to kiss them
- 26:36Speaker 1: when go ahead, Okay. When high school came around, I
- 26:40Speaker 1: had a lot of friends, but I began feeling bad
- 26:42Speaker 1: about myself because I never had a boyfriend. No one
- 26:45Speaker 1: was interested in dating me. I was always the best
- 26:47Speaker 1: friend who was just one of the guys. Wait, Chuck,
- 26:51Speaker 1: I'm confused. Is this is from a guy or a girl?
- 26:53Speaker 1: From a girl? I took a long time. It took
- 26:56Speaker 1: a long time, but eventually gained a tentative piece just
- 27:00Speaker 1: being single. Then one day strings swelling. Then one day
- 27:05Speaker 1: I met Dylan Awesome. We became friends. Six months later,
- 27:09Speaker 1: a miracle happened. He actually was interested in me and
- 27:12Speaker 1: I was interested in him. At the same time we
- 27:16Speaker 1: started dating. We had our first kiss, which quickly turned
- 27:18Speaker 1: into a full blown makeout, which you know, usually the
- 27:22Speaker 1: first kis stuff that's going from you know, zero to
- 27:26Speaker 1: sixty pretty fast. Right. It was amazing and completely worth
- 27:31Speaker 1: waiting for. We are still together and the kisses are frequent.
- 27:34Speaker 1: All to say that I want to encourage, Here's where
- 27:36Speaker 1: the good message comes in. All to say that I
- 27:38Speaker 1: want to encourage anyone out there who feels like they
- 27:40Speaker 1: are a late bloomer in life and the romance department.
- 27:43Speaker 1: I believe there's a lid for every pot, and someday
- 27:46Speaker 1: that person who was worth the weight will show up
- 27:49Speaker 1: in your life. I'm a side note. When I first
- 27:52Speaker 1: started listening to your podcast, I thought the woman at
- 27:53Speaker 1: the beginning was saying from house to Forks dot com.
- 28:00Speaker 1: I was very confused how it related. That is from
- 28:02Speaker 1: Leah in Calgary, Alberta, Canada. Earth, Leah, thank you very
- 28:07Speaker 1: much for writing in stay warm up there in Calgary
- 28:11Speaker 1: this winter. That was a late bloomer, not um, you're
- 28:17Speaker 1: just going that well, you threw me off. I want
- 28:21Speaker 1: to hear some late bloomer stories that are none. I
- 28:24Speaker 1: was just a late bloomer and their people bloom at
- 28:26Speaker 1: different times, and I'm still blooming buddy, I want to
- 28:29Speaker 1: hear late bloomer stories that don't necessarily have anything to
- 28:32Speaker 1: do with kissing. But if you bloomed lately in some realm,
- 28:37Speaker 1: I want to hear about it. Do you want to
- 28:38Speaker 1: hear about it? Absolutely? We want to hear some emails
- 28:41Speaker 1: about it. You can wrap it up and send it
- 28:44Speaker 1: to stuff Podcasts at how stuff works dot com for
- 28:53Speaker 1: moral on this and thousands of other topics. Is it
- 28:55Speaker 1: how stuff works dot com. To learn more about the podcast,
- 28:58Speaker 1: Click on the podcast on in the upper right corner
- 29:01Speaker 1: of our homepage. The House staff Works iPhone app has arrived.
- 29:04Speaker 1: Download it today on iTunes. M HM brought to you
- 29:10Speaker 1: by the reinvented two thousand twelve camera. It's ready, are
- 29:13Speaker 1: you