Latest / Morning Medical with Dr. Chow / Exercise and Gut Health, Mental Health Apps, and Listeria Outbreak in Canada
Transcript
- 0:00Good morning and welcome to Morning Medical with Dr.
- 0:03Chow.
- 0:04I am Dr.
- 0:05Chi-Ming Chow, and today we have some exciting topics to discuss that could have a significant
- 0:11impact on your health and well-being.
- 0:16First up, let us talk about how exercise can improve your gut health.
- 0:22This might not be the first benefit you think of when you lace up your running shoes, but it
- 0:27is a significant one.
- 0:29Recent research has been shedding light on how physical activity can positively influence the
- 0:36gut microbiome, which is the community of microorganisms living in our digestive tracts.
- 0:42The gut microbiome plays a crucial role in many aspects of our health, including digestion,
- 0:47immunity, and even mental health.
- 0:50An imbalance in this microbial community can lead to a range of health issues, from
- 0:55inflammatory bowel disease to obesity and depression.
- 0:59So, maintaining a healthy gut microbiome is essential.
- 1:03Exercise, it turns out, can be a powerful tool in achieving this balance.
- 1:08Studies have shown that regular physical activity can increase the diversity of the gut
- 1:12microbiome.
- 1:14A more diverse microbiome is generally considered healthier and more resilient.
- 1:18This diversity helps the gut better handle various challenges, such as infections or
- 1:23changes in diet.
- 1:26One study conducted by researchers at the University of Illinois found that exercise can
- 1:30lead to an increase in the production of short-chain fatty acids.
- 1:34These are compounds produced by gut bacteria that have anti-inflammatory properties and can
- 1:40help protect against diseases such as type 2 diabetes and heart disease.
- 1:45Moreover, exercise has been shown to enhance the production of beneficial gut bacteria, such
- 1:52as those that produce butyrate.
- 1:54Butyrate is a short-chain fatty acid that serves as a primary energy source for cells
- 1:59lining the colon.
- 2:01It has been linked to reduced inflammation and improved gut barrier function, which can
- 2:06prevent harmful substances from entering the bloodstream.
- 2:10Interestingly, the type and intensity of exercise can influence the gut microbiome
- 2:15differently.
- 2:16For example, moderate-intensity aerobic exercises, such as brisk walking or cycling,
- 2:22have been found to be particularly effective in promoting gut health.
- 2:26High-intensity exercises, like sprinting or heavy weight lifting, also have benefits but
- 2:31might affect the gut microbiome differently.
- 2:35It is also worth noting that the positive effects of exercise on the gut microbiome can
- 2:40be seen in both young and older adults.
- 2:44This means it is never too late to start reaping the benefits of physical activity for
- 2:49your gut health.
- 2:51Even if you have not been active for a while, gradually incorporating exercise into your
- 2:55routine can make a difference.
- 2:58So, what is the takeaway here?
- 3:01Incorporating regular physical activity into your lifestyle is not just good for your heart,
- 3:07muscles, and mental well-being, but it is also beneficial for your gut health.
- 3:14Whether it is a daily walk, a bike ride, or a session at the gym, moving your body can help
- 3:20keep your gut microbiome in balance.
- 3:23That is all for this segment.
- 3:26Stay tuned as we delve into more fascinating health topics today on Morning Medical with Dr.
- 3:32Chow.
- 3:34The recent surge in people seeking mental health care across the country has led to long
- 3:38wait times for first appointments with therapists and psychiatrists.
- 3:44Now, a new study offers hope that while they wait to get care, patients could still get some
- 3:49relief by using evidence-based smartphone applications and wearable devices to track
- 3:54sleep and activity.
- 3:56The study shows that depression and anxiety symptoms, and suicidality, all decreased
- 4:02measurably when patients were assigned to mobile applications that incorporated
- 4:06mindfulness practices, cognitive-behavioral therapy skills, or prompts that encouraged
- 4:12mood-enhancing activities.
- 4:15The study, conducted at Michigan Medicine, the University of Michigan's academic medical
- 4:19center, is published in JAMA Network Open.
- 4:22It involved just over two thousand patients scheduled to get care in the coming weeks from
- 4:27a mental health provider at outpatient University of Michigan Health or University of
- 4:31Michigan student clinics.
- 4:34Adam Horwitz, Ph.D., the University of Michigan Medical School psychologist who is the paper's
- 4:40lead author, called the results encouraging, with implications for individuals and clinics
- 4:45alike.
- 4:47According to him, having this type of option, especially for people who are motivated enough
- 4:52to seek an appointment and wait for it, could be very valuable when providers have long wait
- 4:57lists.
- 4:58These individuals want to be doing something about their mental health but do not yet have
- 5:03access, so this suggests that providing them with some sort of digital option when their
- 5:07motivation is already high, and they are ready to do something, could begin to make a
- 5:12difference.
- 5:14Nearly all the patients completed standardized mental health assessments both at the start of
- 5:18the study and after six weeks of using the application they had been randomly assigned to
- 5:24install on their smartphone.
- 5:26All participants also wore a study-provided Fitbit or their own Fitbit or smartwatch, to
- 5:32track sleep and physical activity.
- 5:35The study randomly assigned most participants to one of two commercial applications –
- 5:40Silvercloud, which is based on cognitive behavioral therapy principles, and Headspace,
- 5:45which coaches users in mindfulness techniques.
- 5:49Both applications have been shown separately to help alleviate mental health symptoms, but have
- 5:54never been tested against one another.
- 5:57Some study participants were randomly assigned to receive a customized version of the study
- 6:02application called MyDataHelps, either alone or together with one of the commercial
- 6:07applications.
- 6:08Those randomized to receive this application received positive encouraging prompts twice per
- 6:14day based on their activity tracker data -- for example, applauding them for walking or getting
- 6:20a good amount of sleep, or suggesting a simple act to improve their mood.
- 6:25Surprisingly, no matter what group they were in, the participants' scores on standard mental
- 6:31health scales changed for the better by the end of the study period.
- 6:36At the start of the study, depression scores on average were just under thirteen on the
- 6:41twenty-seven-point PHQ-9 scale; all groups dropped by two to three points by six weeks.
- 6:48Scores on the twenty-one-point GAD-7 anxiety scale dropped by one point five to two points
- 6:54across the board.
- 6:57Meanwhile, scores on measures of protection against suicide risk increased slightly, with
- 7:02the most improvement among participants using Headspace.
- 7:06Scores on the suicide risk measurement dropped slightly across the board, indicating lower
- 7:10risk for suicidal behavior.
- 7:13Most of the study participants had their initial appointment with a University of
- 7:17Michigan mental health provider before the end of that six-week period, but the drop in mental
- 7:22health scores was similar for those who had not yet started professional treatment.
- 7:28Horwitz notes that the newly published study, called PROMPT, helped inform the development of
- 7:33a much larger study called COMPASS based at the University of Michigan that just got seventeen
- 7:38point nine million dollars in funding from the National Institute of Mental Health.
- 7:44The COMPASS study will involve not only smartphone applications, wearable activity
- 7:50trackers and standardized mental health assessments, but also genetic tests and other
- 7:56types of data collection.
- 7:58It will involve thousands of University of Michigan Health and University of Michigan
- 8:03student clinic patients who are waiting for their first mental health-related appointment.
- 8:09Both PROMPT and COMPASS seek to help researchers develop a more personalized
- 8:14approach to mental health care.
- 8:16They hope to identify which characteristics make someone more likely to respond positively
- 8:20to different forms of treatment or support, so they can use this knowledge to reduce the time
- 8:25it takes to find the approach that helps each individual.
- 8:30Horwitz notes that people seeking mobile-based mental health support have many applications to
- 8:35choose from – and that most of those applications have not gotten scrutiny through
- 8:39objective research.
- 8:41Headspace and Silvercloud have more objective evidence behind them than most of these
- 8:45applications, he notes.
- 8:47He and his colleagues were surprised but encouraged to see improvement in the group
- 8:52using the customized version of MyDataHelps, too.
- 8:56Part of the reason may have to do with the study population: people who were motivated to
- 9:00seek help for mental health concerns, had already been on a waiting list to get
- 9:04scheduled, and now had been scheduled and were waiting to be seen.
- 9:10Because mental health conditions can wax and wane in their symptom severity, applications
- 9:15that support someone during an especially low-mood or high-anxiety time could be
- 9:20important for helping them endure the time until their first appointment.
- 9:26Horwitz notes that the study participants' clinical providers did not have access to their
- 9:30application data.
- 9:32But, he said, this might be a potential option for clinics moving forward if patients want to
- 9:36grant that access by allowing their application to share a summary with their clinic.
- 9:42Data from mental health applications could even potentially help providers or systems
- 9:47understand which patients need the most-intensive approaches to psychiatric care,
- 9:51and which might be able to do all right with less-intensive care.
- 9:55That could also improve the waiting list situation for all patients, he notes.
- 10:00He likens this to a relay race.
- 10:03If we can use applications to give the patient a bit of momentum on understanding and managing
- 10:08their symptoms, even before they get to clinic, then perhaps that will help them get more out
- 10:13of therapy once they get to clinic and pass the baton from the application to a professional
- 10:19provider.
- 10:20The applications do not have the same effect as therapy, but doing something while waiting is
- 10:26still important.
- 10:28In addition to Horwitz, the study's authors are Elizabeth D.
- 10:32Mills, Ph.D., of the University of Michigan Department of Anesthesiology, Srijan Sen, M.D.,
- 10:39Ph.D., and Amy S.B.
- 10:41Bohnert, Ph.D.
- 10:44Sen, a professor of psychiatry, directs the University of Michigan Eisenberg Family
- 10:49Depression Center and is a member of the Michigan Neuroscience Institute; Bohnert is
- 10:53co-director of the University of Michigan Opioid Research Institute and a professor of
- 10:58anesthesiology.
- 11:00Bohnert and Sen are two of the three leaders of the COMPASS study.
- 11:06The PROMPT study was funded by Precision Health at the University of Michigan and the Eisenberg
- 11:11Family Depression Center as well as the National Institute of Mental Health.
- 11:16Next, let us discuss Listeria contaminations in Canada, which have been making headlines
- 11:22recently.
- 11:23From pre-packaged salads to six-layer bean dips to mushrooms, the latest contamination involves
- 11:28some plant-based beverages.
- 11:31This is not the first time food or drink products have been recalled due to Listeria in
- 11:36Canada.
- 11:38Listeria monocytogenes, widely referred to as Listeria, can be found in soil, vegetation,
- 11:45sewage, and water, as well as in the feces of both animals and humans.
- 11:51People who eat foods contaminated with Listeria may carry the bacteria and not develop
- 11:56listeriosis, but in other cases, it can be deadly.
- 12:01More than a week after the Canadian Food Inspection Agency recalled some oat, almond,
- 12:06and coconut drinks from the Silk and Great Value brands, two people in Ontario have died
- 12:11from listeriosis.
- 12:12In total, Ontario, Quebec, and Nova Scotia have twelve confirmed cases related to this current
- 12:19outbreak, according to the Public Health Agency of Canada.
- 12:24In recent years, about one hundred and thirty-four cases of invasive listeriosis have
- 12:29been reported annually in Canada.
- 12:32In the last few months alone, several products have been recalled over possible Listeria
- 12:37contamination.
- 12:38Recently, enoki mushrooms, certain meat and vegetable products, as well as salad kits and
- 12:44bean dip, were recalled.
- 12:46While none of these incidents led to confirmed cases or deaths in Canada, products had to be
- 12:51tossed due to the risk.
- 12:54So, how does Listeria end up in our food and drinks?
- 13:00Dr.
- 13:01Michael Rieder, a professor in the department of pediatrics, medicine, and pharmacology at
- 13:06Western University, explains that each time you handle a food and process it, you increase the
- 13:12chance of bacteria getting into it.
- 13:14Ultra-processed foods are thought to be at a greater risk of having some type of bacteria in
- 13:20them compared to less processed ones.
- 13:23Keith Warriner, a food scientist at Guelph University in Ontario, adds that outbreaks
- 13:28usually arise from a lapse in the plant's sanitation practices.
- 13:33If you do not do sanitation correctly, you do not monitor it, it does not matter how much you
- 13:38process it, it is going to get contaminated.
- 13:40Though well-established food and drink plants take product safety seriously, monitoring for
- 13:47these contaminations is not always up to speed.
- 13:50The challenge we have is our detection tools are not perfect, says Rieder.
- 13:55Currently, small manufacturers test for bacteria by sending a sample out to a lab.
- 14:01Not every province has a testing facility, so there can be a delay in getting the results
- 14:06back, and by that time, products have likely already been shipped and are sitting on
- 14:11shelves.
- 14:13Plants typically test maybe once a month, some once a week.
- 14:18Rieder says there should be more in-facility testing so that plants get real-time results.
- 14:23A few years ago, he helped create a Listeria test kit, in the hopes of preventing affected
- 14:28products from hitting the shelves.
- 14:31These kits have been approved by the United States Food and Drug Administration and by
- 14:36Health Canada for use in food plants and labs.
- 14:40He says his team is currently working on a swab test that will help manufacturers test whether
- 14:45their environment is also bacteria-free.
- 14:49Listeria monocytogenes is a type of bacteria that can cause listeriosis, a rare but serious
- 14:56illness with symptoms that may start suddenly.
- 15:01But symptoms can also arise up to two months after the bacteria gets into your system.
- 15:06It is sort of like a slow burn, says Lori Burrows, a microbiologist at McMaster
- 15:12University in Hamilton, Ontario.
- 15:14People may not connect the dots between what they ate and getting sick.
- 15:19Symptoms can include vomiting, nausea, cramps, severe headache, constipation, and fever.
- 15:28More severe illness may result in the brain infection meningitis and blood infection in
- 15:33newborns and older adults.
- 15:36Women who are pregnant are also at high risk, as the infection can lead to miscarriage and
- 15:41pregnancy loss.
- 15:43The mom may not feel sick, but it can be very dangerous for the fetus, says Burrows.
- 15:49Dr.
- 15:49Samir Gupta, a respirologist and associate professor of medicine in Toronto, advises that
- 15:55if you know you have consumed a contaminated product and are feeling symptoms like fever,
- 16:00body aches, and watery diarrhea, you should go see a medical provider, especially if you are
- 16:07part of an at-risk group.
- 16:09For people who have a weak immune system, doctors can prescribe antibiotics if they have
- 16:14diarrhea.
- 16:15Stronger antibiotics are given if the patient has a bloodstream infection.
- 16:20Studies suggest that delayed treatment can increase rates of complications and death.
- 16:25Foods tainted with Listeria will not look different, or have a distinct taste or smell.
- 16:31When levels of the bacteria build up on equipment in food processing plants, outbreaks
- 16:36can occur.
- 16:36Listeria can be killed through cooking or pasteurization, but researchers have shown that
- 16:42the bacteria can even survive in fridges and freezers.
- 16:46There are a number of ways you can lower your risk of getting listeriosis.
- 16:51These include washing your hands before and after handling food, cleaning fruits and
- 16:55vegetables, and avoiding certain foods like raw, unpasteurized milk, soft cheeses, or raw
- 17:02meats.
- 17:03Canadians can keep track of product recalls and safety alerts through the Canadian Food
- 17:06Inspection Agency's website.
- 17:09That is all for today’s episode of Morning Medical with Dr.
- 17:13Chow.
- 17:14I am Dr.
- 17:15Chi-Ming Chow, thanking you for tuning in.
- 17:19Stay healthy and informed, and join us next time for more insights into the world of health
- 17:25and medicine.
- 17:26Have a great day!