Latest / Wellness, Actually with Emily Oster & Perry Wilson, MD / Understanding Panic Headlines: How studies that influence your parenting choices get published
Transcript
- 0:01Speaker 1: I'm Emily Oster. This is parent Data, and today.
- 0:05Speaker 2: New tests reveal popular cereals and snacks could have potentially
- 0:10Speaker 2: dangerous levels of the same chemical found in weed killer.
- 0:17Speaker 3: Here at parent Data, we talk a lot about panic headlines,
- 0:22Speaker 3: you know, the headlines.
- 0:23Speaker 1: That cycle through your feed about coffee.
- 0:25Speaker 3: And wine and sleep and lead and the causes of autism.
- 0:29Speaker 3: And many of the panic headlines contradict the last panic headline.
- 0:34Speaker 3: Some of them end up debunked, or maybe there was
- 0:37Speaker 3: a math error. They're not as scary as they originally seem,
- 0:40Speaker 3: but in the moment these feel so scary and urgent.
- 0:45Speaker 1: There is new research that impacts you if you're a
- 0:47Speaker 1: coffee drinker.
- 0:48Speaker 4: Can more screen make your child autistic? Nearly forty percent
- 0:53Speaker 4: of parents use white noise machines to help their children
- 0:56Speaker 4: sleep sounder and longer. However, some health experts are concerned
- 0:59Speaker 4: about the effects that these machines could be having on
- 1:02Speaker 4: a child's brain development.
- 1:03Speaker 5: More and more women are actually throwing out their tampons,
- 1:06Speaker 5: opting out of using tampons for fears of toxic chemicals
- 1:09Speaker 5: that could be harmful, according to.
- 1:11Speaker 1: A recent Consumer Reports start a news study from.
- 1:13Speaker 4: Japan study on rats show that those raised in continuous way. Today,
- 1:17Speaker 4: researchers in Japan say the more time your child is
- 1:21Speaker 4: exposed to it, the more likely they could land on
- 1:24Speaker 4: the autism spectrum.
- 1:25Speaker 1: The study was conducted between one.
- 1:30Speaker 3: If you're a parent just trying to follow the science,
- 1:33Speaker 3: do what's best for your kid. Sometimes it feels like
- 1:36Speaker 3: you're being absolutely and really nonsensically bombarded with the wrong
- 1:41Speaker 3: things to do. And when it all feels like too much,
- 1:45Speaker 3: I like to call doctor Babu. Jenna Babu is an
- 1:49Speaker 3: economist like me, but unlike me, he's also a medical
- 1:53Speaker 3: doctor and he loves natural experiments, which means an experiment
- 1:59Speaker 3: he can't can observing people existing in naturally occurring circumstances.
- 2:05Speaker 3: For example, he has some excellent work on flu shots
- 2:09Speaker 3: showing that kids whose birthdays fall in the fall are
- 2:13Speaker 3: more likely to get their flu shots because they can
- 2:15Speaker 3: get them at their yearly well visits. And then he's
- 2:19Speaker 3: able to study the impact on flu shots and find,
- 2:22Speaker 3: for example, the kids are less likely to get the flu, and.
- 2:25Speaker 1: So are their elderly relatives.
- 2:27Speaker 3: This isn't a randomized trial that you can set up yourself.
- 2:32Speaker 3: This is finding something clever in the data that can
- 2:36Speaker 3: allow you to generate a causal estimate even though it
- 2:41Speaker 3: hasn't been explicitly randomized. If you've read Freakonomics, you're familiar
- 2:47Speaker 3: with this kind of research. And for me, I love
- 2:50Speaker 3: this stuff and I love BAPU, And the reason we
- 2:54Speaker 3: brought them back today is because we wanted to talk
- 2:56Speaker 3: about how research can be abused on it makes its
- 3:00Speaker 3: way into the world. I wanted to talk about how
- 3:04Speaker 3: we get to that splashy headline that warns you that
- 3:07Speaker 3: there's lead in your cheerios, or you have to throw
- 3:09Speaker 3: out all your black plastic cooking utensils, or how screens
- 3:13Speaker 3: give your kids autism?
- 3:15Speaker 1: How do we get there?
- 3:17Speaker 3: How does the research that informs that get published If
- 3:23Speaker 3: it's not the researchers aim to make us worry, they're
- 3:25Speaker 3: just curious data nerds. Why does it feel like they're
- 3:29Speaker 3: colluding with the newspapers to scare the crap out of parents.
- 3:33Speaker 3: So that's what PAPU and I are going to talk about,
- 3:35Speaker 3: what the researchers are actually aiming to do, and then
- 3:38Speaker 3: what happens to that research when it arrives in your
- 3:41Speaker 3: headlines to freak you out. We talk about the complicated
- 3:45Speaker 3: relationship between causality and correlation, the academic and popular incentives
- 3:50Speaker 3: to publish these kinds of headlines, and also who decides
- 3:54Speaker 3: what research is worth sharing with the world. This is
- 3:59Speaker 3: on the fase conversation about research, but really it's about
- 4:02Speaker 3: reassurance that there are a lot of reasons behind publishing
- 4:05Speaker 3: a story about lead and cheerios that have nothing to
- 4:08Speaker 3: do with you, or how dangerous cheerios actually are, or
- 4:12Speaker 3: whether you're a good parent who cares about the health
- 4:14Speaker 3: and well being of your kids. You are, and you
- 4:17Speaker 3: do don't throughout your cheerios. But also, if you're curious,
- 4:21Speaker 3: listen to the journey that headline chok to land in
- 4:23Speaker 3: your lap.
- 4:26Speaker 1: After the break, Doctor Babu.
- 4:28Speaker 3: Jenna, Babu Jenna, thanks for joining me.
- 4:39Speaker 2: Thank you for having me.
- 4:42Speaker 3: You've actually been on the Parent Data podcast before, but
- 4:46Speaker 3: for people who weren't listening, like you know, two and
- 4:48Speaker 3: a half years ago or whenever.
- 4:50Speaker 1: I had you. Could you introduce yourself?
- 4:53Speaker 2: First of all, it feels like yesterday, but that's right.
- 4:55Speaker 1: Oh, it just feels it's so such a treat. You're
- 4:58Speaker 1: always in my.
- 4:58Speaker 5: Head except yeah, my name is Babu Jenna. I'm an economist,
- 5:04Speaker 5: physician and professor at Harvard Medical School. I have a
- 5:09Speaker 5: book called Random acx of Medicine with Chris Worsham, and
- 5:12Speaker 5: a podcast called Freaconomics MD.
- 5:16Speaker 1: I think it's important to emphasize that although you.
- 5:17Speaker 3: Start with being an economist, you are, unlike me, also
- 5:21Speaker 3: an actual doctor.
- 5:24Speaker 2: That's true. I'm a doctor doctor.
- 5:26Speaker 1: Yeah, you see patients.
- 5:28Speaker 2: I do.
- 5:29Speaker 5: I was actually just on service for a couple of
- 5:31Speaker 5: weeks at Mass General in Boston.
- 5:34Speaker 1: In the emergency room or no, I work.
- 5:37Speaker 2: In the general medical floor.
- 5:38Speaker 5: So I spent about two weeks there in a stretch,
- 5:41Speaker 5: and so I just finished up yesterday.
- 5:44Speaker 3: Do you feel like you get a lot of ideas
- 5:46Speaker 3: for your economics work from your doctoring?
- 5:50Speaker 5: Yeah?
- 5:50Speaker 2: I do.
- 5:51Speaker 3: Yeah.
- 5:51Speaker 5: I mean there's like all sorts of random things that
- 5:53Speaker 5: you see in the hospital, things that patients will say,
- 5:57Speaker 5: or problems that you'll encounter, which I think certainly have
- 6:02Speaker 5: you given me ideas in the past. A couple of
- 6:03Speaker 5: ideas came from things I saw in the hospital.
- 6:05Speaker 1: I'm just always curious about that.
- 6:07Speaker 3: You seem like a person who gets many of your
- 6:09Speaker 3: research ideas from just walk like walking around in the
- 6:12Speaker 3: world or things that happened in your own life.
- 6:15Speaker 5: Yeah, and chat GPT is feels quite good at this.
- 6:18Speaker 5: I don't know if you've tried it for coming up
- 6:19Speaker 5: with ideas, but it's not bad.
- 6:22Speaker 3: Were you just write in like, I need a research idea.
- 6:25Speaker 3: I'm a crazy doctor who likes natural experiments. Give me
- 6:28Speaker 3: a research idea.
- 6:29Speaker 2: Yeah.
- 6:29Speaker 5: So, for example, I had some dinner with some students
- 6:32Speaker 5: at Harvard the other night, and we were talking about
- 6:34Speaker 5: chat GPT, and so I said to the bart you know,
- 6:37Speaker 5: suppose I want to study whether or not playing football
- 6:42Speaker 5: as a youth impacts.
- 6:43Speaker 2: Your long term health.
- 6:45Speaker 5: And so I asked, chat GPT, that's what I want
- 6:47Speaker 5: to know. Give me some natural experiments to try to
- 6:51Speaker 5: figure this out. And CHATCHEPT came up with a couple
- 6:53Speaker 5: of good ideas. It says, all right, well, let's look
- 6:55Speaker 5: at whether or not Pop Warner programs come into certain
- 7:00Speaker 5: at certain times. Let's look at age cutoffs, let's look
- 7:04Speaker 5: at changes in policies towards contact versus no contact football.
- 7:10Speaker 5: You know, all very plausible ideas. And I don't think
- 7:12Speaker 5: anybody has studied this question before, and so it was
- 7:16Speaker 5: remarkable that it was able to come up with ideas
- 7:18Speaker 5: that all made a lot of sense. None of them
- 7:20Speaker 5: I would pursue, but not bad.
- 7:23Speaker 2: Not bad.
- 7:25Speaker 3: I feel like my use of GPT is more limited.
- 7:29Speaker 3: Yesterday I had it make me an image of Elf
- 7:31Speaker 3: on the shelf, which was actually very was actually very good. Okay,
- 7:36Speaker 3: But the purpose of this call is not to advertise
- 7:39Speaker 3: the products of open AI, which is not a not
- 7:43Speaker 3: a sponsor, but to talk about a topic that I
- 7:48Speaker 3: think you and I both care a lot about, which
- 7:51Speaker 3: is why so much of the research that people hear
- 7:56Speaker 3: about in the world is just correlation and not causation.
- 8:03Speaker 1: And you know, we've I talk about this a.
- 8:05Speaker 3: Lot, and I guess that the I want to sort
- 8:08Speaker 3: of set the stage for the problem that we're talking about,
- 8:11Speaker 3: But then I actually want to talk about like why
- 8:13Speaker 3: this happens, which for me is the more interesting, the
- 8:15Speaker 3: more interesting question. So, uh, the canonical example of this
- 8:19Speaker 3: problem is, you know, the sort of studies show that
- 8:24Speaker 3: you know, new studies shows that you know, coffee like
- 8:29Speaker 3: generates makes you live, you know, generates higher longevity, or
- 8:33Speaker 3: new study shows that coffee makes you die sooner, or
- 8:37Speaker 3: you know new A lot of this stuff happens in nutrition,
- 8:39Speaker 3: and it's kind of.
- 8:40Speaker 1: Either specific or it can be very general.
- 8:42Speaker 3: You know, new study shows that, like people who consume
- 8:45Speaker 3: more ultra processed foods, you die sooner. And and these
- 8:50Speaker 3: are places where often when people send them to me,
- 8:53Speaker 3: then I say, you know it's correlation and not causation,
- 8:56Speaker 3: but can you give me your answer?
- 8:59Speaker 1: You know, I'm your page.
- 9:00Speaker 3: I come and I say, I saw this new study
- 9:01Speaker 3: that says blah blah blah about coffee, Like, how do
- 9:04Speaker 3: you help me understand what is the problem with that?
- 9:08Speaker 3: What are some of your concerns about that study?
- 9:11Speaker 5: Well, so, typically if someone going to ask me that
- 9:14Speaker 5: kind of question, I'd say, all right, Well, if their
- 9:16Speaker 5: goal is to understand whether taking this medication, taking this supplement,
- 9:22Speaker 5: drinking coffee is going to actually improve the quality or
- 9:27Speaker 5: length of their life, how would you study it? And
- 9:29Speaker 5: I'd say to them, the only way to really study
- 9:31Speaker 5: this is to do a randomized trial where you take
- 9:34Speaker 5: a bunch of people and you randomize some of them
- 9:37Speaker 5: to getting.
- 9:40Speaker 2: The product.
- 9:40Speaker 5: In this case, it could be coffee, it could be medication,
- 9:43Speaker 5: And you take an otherwise similar group of people and
- 9:46Speaker 5: you randomize them to not getting that, and then you
- 9:50Speaker 5: study differences in whatever outcome you care about. It could
- 9:53Speaker 5: be blood pressure, could be weight, could be how long
- 9:56Speaker 5: you live. And if you see something there, then you
- 9:59Speaker 5: can say it's because of the thing that you did,
- 10:02Speaker 5: in this case drinking coffee. In the real world, though,
- 10:06Speaker 5: you don't have that randomization for the most part, and
- 10:08Speaker 5: so you have people who drink a lot of coffee
- 10:10Speaker 5: and people who don't. And I would explain to them
- 10:12Speaker 5: that people who drink a lot of coffee are different
- 10:14Speaker 5: than people who don't. And because of that, you don't
- 10:17Speaker 5: know if it's the coffee that's leading to this health
- 10:20Speaker 5: outcome or everything else that is different in those people
- 10:24Speaker 5: who drink a lot of coffee. And I think most
- 10:27Speaker 5: most people would understand that idea if told in that way.
- 10:31Speaker 3: I mean, the other thing I will sometimes tell people
- 10:35Speaker 3: is think about this choice and think about whether it
- 10:40Speaker 3: seems like people are making it randomly. So people say,
- 10:44Speaker 3: you know, there's a relationship between family dinner, you know,
- 10:47Speaker 3: having a family dinner, homegook, family meal every night, and
- 10:50Speaker 3: outcomes for kids and your school outcomes.
- 10:53Speaker 1: Just ask them to think about, you know.
- 10:55Speaker 3: Once you accept the best way to do this would
- 10:57Speaker 3: be randomization, you would ask sort of compare groups who
- 11:00Speaker 3: do it and who do not. How close is that
- 11:03Speaker 3: to randomization? Like how much randomness do you think there
- 11:06Speaker 3: is in this choice? And with many of these choices
- 11:09Speaker 3: like what I eat or whether I have family dinner
- 11:11Speaker 3: or whatever it is, it doesn't really seem very random.
- 11:16Speaker 3: It doesn't seem like there's a very important component of
- 11:18Speaker 3: randomization there. That's like the world is not doing a
- 11:21Speaker 3: good job randomizing for you.
- 11:23Speaker 5: Yeah, and another way to put it, and we have
- 11:26Speaker 5: a technical term that we use in our studies called
- 11:29Speaker 5: falsification tests. I would say to them, all right, suppose
- 11:32Speaker 5: that I showed you that people who drive expensive cars
- 11:35Speaker 5: live longer. Would you say to me that buying an
- 11:39Speaker 5: expensive car will make you live longer? And most people
- 11:42Speaker 5: say no, absolutely not. And I'd say, well, what if
- 11:45Speaker 5: it's the case that people who drink a lot of
- 11:46Speaker 5: coffee drive fancy your cars or something like that. Then
- 11:50Speaker 5: they would sort of get Okay, I get it. There's
- 11:52Speaker 5: like there's there are other factors that are going to
- 11:54Speaker 5: be correlated with some outcome, but could not plausibly be
- 11:59Speaker 5: so in a ca.
- 12:01Speaker 3: My favorite thing I ever did about this was a
- 12:03Speaker 3: time when I took every food in the National Health
- 12:07Speaker 3: and Nutrition Examination Survey, and I correlated it with the weight,
- 12:11Speaker 3: and I showed that like, for example, dandelion greens are
- 12:15Speaker 3: associated with a lower weight, but iceberg lettuce is associated
- 12:18Speaker 3: with having a higher weight, And.
- 12:20Speaker 1: Like you know, chemical based.
- 12:22Speaker 3: Sugar substitutes are associated with higher weight, but plant based
- 12:25Speaker 3: sugar substitutes are associated with lower weight, which for me
- 12:28Speaker 3: was like such an illustration of like, you know, who's
- 12:31Speaker 3: eating iceberg lettuce?
- 12:31Speaker 1: Who's eating what kind of idiots eating dandelion greens? You know,
- 12:34Speaker 1: it's like my dad and he's also doing every other thing.
- 12:37Speaker 3: And I think that kind of thing can make this
- 12:39Speaker 3: quite vivid when you're just like, you know, well, actually,
- 12:44Speaker 3: what do you.
- 12:44Speaker 1: Think is going on?
- 12:45Speaker 3: And as soon as you point that out to someone,
- 12:46Speaker 3: the fancy car is a good example, it's like, oh yeah, okay,
- 12:51Speaker 3: Like it's not that this is not that complicated a
- 12:54Speaker 3: point to make two people I find.
- 12:57Speaker 5: Yeah, yeah, but I mean, just to be fair, they're
- 13:00Speaker 5: pretty high quality evidence about dan line greens and dimension
- 13:04Speaker 5: that's not true, there's not Can I just ask a
- 13:08Speaker 5: clarifying question when you say dandelion greens, are those the
- 13:11Speaker 5: same thing as those fancy little microgreens that you get.
- 13:14Speaker 3: No, a dan lion green is literally a part of
- 13:17Speaker 3: a dandelion. It's like instead of eating, you don't eat
- 13:20Speaker 3: the flower, but.
- 13:21Speaker 1: You eat the greens.
- 13:23Speaker 3: Yeah, microgreens are a delicious treat associated with uh, you know,
- 13:28Speaker 3: higher rates of IQ.
- 13:30Speaker 5: Or I'll say the following though, that's like, you know,
- 13:33Speaker 5: the astute listener will know that my name is A
- 13:36Speaker 5: is an Indian name, and so it's not uncommon for
- 13:39Speaker 5: Indian people to take flowers and like like fry them
- 13:43Speaker 5: in some like flour like do it comes out delicious?
- 13:46Speaker 2: I don't think it's healthy though.
- 13:48Speaker 3: Right, the flowers might be good for you, but the
- 13:52Speaker 3: frying somewhat negates It's actually that people are frying their
- 13:56Speaker 3: iceberg lettice.
- 13:57Speaker 2: That's exactly exactly.
- 14:01Speaker 4: So.
- 14:01Speaker 3: A thing I find puzzling about this space is I
- 14:07Speaker 3: feel like if you explained this, and I have to
- 14:11Speaker 3: my thirteen year old, this concept that you know, correlation
- 14:16Speaker 3: is not causation and that you would really want to
- 14:20Speaker 3: worry quite a lot about the other things that might
- 14:25Speaker 3: be driving these relationships.
- 14:26Speaker 1: I feel like that is a.
- 14:27Speaker 3: Very intuitive idea, and you know, not that like everybody
- 14:31Speaker 3: sees it immediately, but that it isn't very hard for
- 14:33Speaker 3: people to understand. Even in a you know, a short conversation,
- 14:37Speaker 3: you can kind of get people to see it. I mean,
- 14:39Speaker 3: I think, you know, I spend a lot of time
- 14:41Speaker 3: on Instagram short form Instagram videos.
- 14:43Speaker 1: Explaining this, and I think some of the time it hits.
- 14:46Speaker 3: The question I find more puzzling is why are there
- 14:49Speaker 3: so many papers which do this, which are written by
- 14:53Speaker 3: people who haven't just watched a forty five second Instagram
- 14:57Speaker 3: video or had one conversation with you, but who have
- 15:00Speaker 3: spent literally many, many years taking classes on these exact
- 15:06Speaker 3: topics and then writing papers. And these people are, you know,
- 15:10Speaker 3: professors or like, they have a lot of education, They're smart,
- 15:15Speaker 3: and I just fundamentally don't understand why so much of
- 15:20Speaker 3: this literature keeps happening, and whether the people who are
- 15:24Speaker 3: writing it think that they are uncovering something causal or not.
- 15:32Speaker 1: Do you have any insight?
- 15:34Speaker 5: I have answers, I don't know if they're insightful, But well,
- 15:37Speaker 5: let me just say the following. First of all, and
- 15:40Speaker 5: at some point later day, I'm going to tell you
- 15:41Speaker 5: about a paper that we have coming out in probably
- 15:45Speaker 5: a couple of weeks. It will be December, so I
- 15:46Speaker 5: don't know when this will air, but it will fall
- 15:49Speaker 5: into this category of a very weird sort of correlation.
- 15:54Speaker 2: And the.
- 15:57Speaker 5: Way that we would describe it in the way that
- 15:59Speaker 5: we do justscribed as finding, which I know I'm making
- 16:02Speaker 5: it sort of sound very sort of like wow, what's
- 16:04Speaker 5: what's he going to drop on me in a moment?
- 16:07Speaker 5: Is it's just a hypothesis. So I would have no
- 16:10Speaker 5: problem if people would do the kinds of studies that
- 16:13Speaker 5: you're describing, which are purely correlational studies, no sort of experiment,
- 16:18Speaker 5: serving as the backbone behind the idea and saying, look,
- 16:22Speaker 5: here's this interesting observation. We don't know what to make
- 16:25Speaker 5: of it. It could be causal for X, y Z
- 16:28Speaker 5: reason like there's a there's a channel by which this thing,
- 16:33Speaker 5: in this case dandelions, could have an effect on some
- 16:37Speaker 5: health outcome and it would work by this mechanism. You know,
- 16:41Speaker 5: this flower affects this protein in the body. This protein
- 16:44Speaker 5: in the body affects these cells. These cells affect the
- 16:47Speaker 5: development dementia something like that. Totally fine with that, because
- 16:51Speaker 5: then a reader could say, all right, well, you know
- 16:52Speaker 5: I want to investigate this or not investigate and investigate
- 16:55Speaker 5: this any further. But that's not the way the studies
- 16:57Speaker 5: come out. The studies come out as you know, danne
- 17:00Speaker 5: greens are you know, strongly associated with dementia, and therefore
- 17:04Speaker 5: you should eat you know fewer or more of these
- 17:07Speaker 5: day online greens. The question that is to your questions
- 17:09Speaker 5: like why do you see this? And among educated researchers,
- 17:13Speaker 5: I think it's two things. Probably one is I think
- 17:17Speaker 5: that they might at their core believe.
- 17:20Speaker 2: This to be true.
- 17:22Speaker 5: And this is something I've been thinking a lot about now,
- 17:24Speaker 5: which is sort of how do your beliefs impact the
- 17:27Speaker 5: way that you do science, the way that you do research.
- 17:30Speaker 5: I mean, certainly, if you have a belief that something
- 17:33Speaker 5: is right or correct true, you might do research in
- 17:37Speaker 5: a way that validates that, and you might sort of
- 17:39Speaker 5: interpret the findings in a way that that validate that.
- 17:42Speaker 5: So I think that's one problem, and I think that
- 17:44Speaker 5: was something that we've maybe saw a lot of actually
- 17:47Speaker 5: during the COVID nineteen pandemic. And then the other problem
- 17:50Speaker 5: is I think that the incentives aren't there to do
- 17:55Speaker 5: something more like, you know, it takes more work to
- 17:57Speaker 5: do something clever and creative to solve a problem in
- 18:01Speaker 5: a more rigorous way. It takes more effort and more
- 18:03Speaker 5: thinking and more creativity, and if the incentives aren't there
- 18:06Speaker 5: to do that, then you're not going to do that.
- 18:09Speaker 5: And I think in general, medical journals don't require that
- 18:13Speaker 5: as a standard. You know, you write a lot of
- 18:15Speaker 5: economics papers. Economics papers do require that as a standard,
- 18:19Speaker 5: so you would not typically see those kinds of papers
- 18:21Speaker 5: published in the best economics journals, whereas you know, almost
- 18:25Speaker 5: every week in the best medical journals you'll see a
- 18:27Speaker 5: paper like that come out.
- 18:29Speaker 1: Yeah, I mean, I think that's a that's all for me.
- 18:33Speaker 3: Like that is an answer which is almost certainly right,
- 18:35Speaker 3: which is, you know, my incentive as a researcher is
- 18:38Speaker 3: to publish my papers in the best you know in JAMA.
- 18:41Speaker 3: And if JAMA is happy to see a correlation, then
- 18:45Speaker 3: I guess I then I then that's much easier paper
- 18:48Speaker 3: to produce than than you know, something else, And so
- 18:52Speaker 3: maybe I do that. That of course pushes the question
- 18:55Speaker 3: down the line to you know what, why don't the
- 18:58Speaker 3: editors of JAMA understand the difference between correlation and causality?
- 19:02Speaker 1: A question I asked myself frequently, and.
- 19:07Speaker 3: I get the impression when I read these papers that
- 19:12Speaker 3: people think that the kinds of empirical adjustments they do
- 19:16Speaker 3: are sufficient.
- 19:18Speaker 1: I mean, this is like when you read these papers.
- 19:19Speaker 3: So just to sort of back up for people who
- 19:21Speaker 3: don't spend their days in papers about coffee and longevity,
- 19:25Speaker 3: you know, it's very common in research like this for
- 19:28Speaker 3: researchers to talk about adjusting for variables. So they say,
- 19:33Speaker 3: you know, in the data, I see not only do
- 19:35Speaker 3: you eat dandelion greens, and you know how long do
- 19:38Speaker 3: you live? Or do you have dementia. Let's say, let's
- 19:41Speaker 3: keep with our dementia thing. So not only do I
- 19:43Speaker 3: see your dandelion greens and your dementia, but I also
- 19:46Speaker 3: see you know, whether you went to high school, and
- 19:49Speaker 3: you know, some categories of income, and your sex, and
- 19:52Speaker 3: your age and maybe your race, and maybe I see
- 19:57Speaker 3: more whatever it is, and they adjust for those They
- 20:00Speaker 3: use a statistical method to effectively try to match people
- 20:05Speaker 3: with similar values of those variables. It's not usually quite
- 20:08Speaker 3: that technique, but something where I basically said, I'm going
- 20:10Speaker 3: to try to hold constant these other features so I
- 20:14Speaker 3: can be closer to being causal and my view informed
- 20:20Speaker 3: by a lot of the research I've done is that
- 20:22Speaker 3: most of the time that's completely insufficient. And then in fact,
- 20:25Speaker 3: there's tons of things we don't see about people which
- 20:27Speaker 3: are very important for their choices of, say, what to eat,
- 20:30Speaker 3: that are not summarized. A full component of somebody's interest
- 20:34Speaker 3: in their health is not summarized by two categories of
- 20:37Speaker 3: education and three categories of income, and that these are
- 20:40Speaker 3: just really insufficient. But I wonder how much.
- 20:42Speaker 1: Of it is that I just have a particular, I.
- 20:46Speaker 3: Think informed, but maybe unusual view about just how important
- 20:50Speaker 3: unobservables are, and that most of the public health profession
- 20:54Speaker 3: has a different view about how important unobservables are.
- 20:57Speaker 1: I mean, how much do you think it's that?
- 21:02Speaker 5: I think that's part of it. But I'll tell you, you know,
- 21:05Speaker 5: as someone who spent most of my life writing the
- 21:09Speaker 5: kinds of studies where we're trying to find experiments and
- 21:12Speaker 5: publishing them mostly in medical journals, there's a lot of
- 21:18Speaker 5: papers that I've sent to journals where they come back
- 21:21Speaker 5: to me and the paper gets rejected and they'll explain
- 21:25Speaker 5: why they think this is not causal. And I'm always
- 21:30Speaker 5: thinking to myself, Wow, this is like definitely causal.
- 21:33Speaker 2: It may not be important, but it's definitely.
- 21:36Speaker 5: Causal, and we've gone through great lengths to show that
- 21:40Speaker 5: there's a causal relationship here. And it's not as if
- 21:45Speaker 5: the editors don't have an understanding of these ideas, which
- 21:48Speaker 5: is always puzzling to me, because they reject pay And
- 21:52Speaker 5: it's not just me, it's other people who I work
- 21:54Speaker 5: with who are submitting papers that are using these sort
- 21:56Speaker 5: of causal designs, and they'll get rejected. And one of
- 21:59Speaker 5: the reasons they'll get rich is because they'll say, you know,
- 22:01Speaker 5: we're not sure this is causal because of X, Y
- 22:03Speaker 5: and z. But then another paper which is not at
- 22:07Speaker 5: all causal will go through. And the only way I
- 22:11Speaker 5: can sort of rationalize this is to say that I
- 22:14Speaker 5: think everybody knows that these studies that we're talking about
- 22:19Speaker 5: are just can't be true. Like the only way this
- 22:22Speaker 5: makes sense is like they just can't be true, and
- 22:24Speaker 5: so you hold a different standard to them. Even though
- 22:26Speaker 5: the language is there which is sort of close to causal.
- 22:29Speaker 5: There's these disclaimers at the end about how the study
- 22:32Speaker 5: is not causal or you can't interpret anything about the
- 22:34Speaker 5: cause relationships here based on the study design. But I
- 22:38Speaker 5: think that they have an understanding of the issues, but
- 22:40Speaker 5: they are applied differently, And the question might be why
- 22:44Speaker 5: are they applied differently?
- 22:47Speaker 1: Do you think the reason they're implied?
- 22:48Speaker 3: First of all, that's an incredibly cynical view, although perhaps true.
- 22:52Speaker 3: But do you think the reason they're applied differently is
- 22:55Speaker 3: because you, as a journal editor, know that like if
- 23:00Speaker 3: you publish, not that your work is intimportant, but some
- 23:02Speaker 3: of the things that you work on, I think are not.
- 23:05Speaker 3: Some of the things you work on are very headline friendly,
- 23:07Speaker 3: but some of the things you work on are not
- 23:08Speaker 3: very headline friendly. And so you know, like you publish
- 23:12Speaker 3: a Bapuo paper, you know that it's causal, but maybe
- 23:15Speaker 3: the New York Times doesn't care you publish something that says,
- 23:19Speaker 3: you know, ultra processed foods caused dementia, or dandelion greens
- 23:22Speaker 3: don't cause dementia or whatever, like the New York Times,
- 23:25Speaker 3: well section they're calling, they're calling you, yeah, And I mean,
- 23:29Speaker 3: how much do you think that matters?
- 23:32Speaker 5: I think it matters. I'm and you know, as you're
- 23:34Speaker 5: saying that, my mind is sort of racing, like how
- 23:36Speaker 5: could you how could you sort of start to study that?
- 23:39Speaker 5: I mean, I wonder if there are any shocks to
- 23:43Speaker 5: media interest in these topics or something like that where
- 23:47Speaker 5: you could really show that when the New York Times
- 23:50Speaker 5: or something like that becomes interested in a topic, that
- 23:54Speaker 5: you start to see more papers being published in the
- 23:57Speaker 5: top journals on that or something to that, because I
- 24:00Speaker 5: do think that's part of it that the journals are
- 24:03Speaker 5: responding to. I mean, ultimately, the job of the journals
- 24:07Speaker 5: is to create scientific information that shapes the scientific record.
- 24:10Speaker 5: That's your certainly one goal, I think, but the other
- 24:13Speaker 5: is to sort of make sure people read their journal
- 24:15Speaker 5: to be to feel like they're being relevant, Like that's
- 24:17Speaker 5: the core part of their business model. So if they're
- 24:20Speaker 5: not publishing things that people don't want to read, that's
- 24:23Speaker 5: a problem. And one of the things that people have
- 24:26Speaker 5: an appetite for there's a demand for is this kind
- 24:29Speaker 5: of science. Now why that is I don't know, Or
- 24:34Speaker 5: why there's a demand for this low quality science, I
- 24:37Speaker 5: don't know. I mean, I certainly understand why there's an
- 24:39Speaker 5: interest in understanding whether or not coffee has an effect
- 24:41Speaker 5: in your life or all these things that we are
- 24:43Speaker 5: sort of do all the time.
- 24:46Speaker 1: Yeah, I mean, I think people.
- 24:50Speaker 3: Part of the reason for the demand is like if
- 24:52Speaker 3: you as the now we're like on one step you
- 24:55Speaker 3: know below this, But like the New York Times would
- 24:58Speaker 3: like people to click on their things and read them.
- 25:01Speaker 3: And something that says, you know, coffee has this effect,
- 25:05Speaker 3: or you know, plastics have or whatever. It is like
- 25:08Speaker 3: something that sort of causes people to worry about a
- 25:12Speaker 3: topic that is relevant for their lives. That is a
- 25:16Speaker 3: great thing to get people to click on. That's like
- 25:19Speaker 3: popular click clicker location.
- 25:22Speaker 2: Yeah, I mean there's a question of sort of what.
- 25:24Speaker 5: I don't know that the right word here is research integrity,
- 25:27Speaker 5: But you know, I will sometimes see things where people
- 25:31Speaker 5: will landbast a journalist for talking about a study that's
- 25:36Speaker 5: clearly not causal. And my view is, like, why are
- 25:38Speaker 5: we picking on the journalists. The journalist wasn't trained to
- 25:41Speaker 5: do this, right, We should be picking on the journal itself,
- 25:43Speaker 5: the journal editors, or even the researchers who decided to
- 25:47Speaker 5: do that, like they really should know better, and yet
- 25:52Speaker 5: they're they're doing that. And I think that, like, again,
- 25:55Speaker 5: we can always quibble about what's an important study or
- 25:58Speaker 5: a creative study that I would have no problem debating that,
- 26:02Speaker 5: But I think that most people can agree that certain
- 26:05Speaker 5: studies are just not likely to be right, or you
- 26:08Speaker 5: have no idea whether they're right or wrong. And I
- 26:10Speaker 5: think people would agree with that.
- 26:12Speaker 3: I mean, I think that's I find that very cynical,
- 26:15Speaker 3: and I think maybe a different way to say it
- 26:17Speaker 3: is I think it goes back to this thing you
- 26:19Speaker 3: said at the beginning about sort of people believe something
- 26:22Speaker 3: to be true, you know, if I believe it to
- 26:24Speaker 3: be true for whatever reason based on the outside, you know,
- 26:28Speaker 3: like based on other things I know about the world,
- 26:30Speaker 3: maybe from better studies, maybe something. If I really have
- 26:33Speaker 3: a core belief that like eating more ultra process foods
- 26:35Speaker 3: is bad for you, which I think is a belief
- 26:37Speaker 3: that many people have and may be a reasonable belief,
- 26:41Speaker 3: and then I publish a study in which there's a
- 26:44Speaker 3: correlation between you know, the share of your food that's
- 26:47Speaker 3: ultra processed and your health outcome, of which there are
- 26:50Speaker 3: many studies, even though almost all of those studies really
- 26:55Speaker 3: it's very hard to know how much of that affect
- 26:58Speaker 3: is the food and how much is all of the
- 26:59Speaker 3: other differences. And really maybe you would dig into people
- 27:02Speaker 3: and they would say, well, yeah, you know, there's probably
- 27:04Speaker 3: some other confounds that the fact that they they're more
- 27:07Speaker 3: comfortable saying to a journalist, you know, people should eat
- 27:11Speaker 3: less ulster processed foods, because they're coming in with the
- 27:15Speaker 3: belief that that is right, and that this is this
- 27:18Speaker 3: paper reinforces something which they really already thought it was true.
- 27:21Speaker 3: And even if you said, well, this particular paper didn't
- 27:23Speaker 3: really add that much to my knowledge, I was already
- 27:26Speaker 3: very sure that was true. And so I'm comfortable saying
- 27:28Speaker 3: that it should change people's behavior, not so much because
- 27:31Speaker 3: this particular piece of evidence that we've produced, but just
- 27:34Speaker 3: because I generally think that that's the thing people should do,
- 27:36Speaker 3: and this is an opportunity to express Then.
- 27:39Speaker 5: Yeah, I totally agree. It's such a hard question to study.
- 27:43Speaker 5: I mean, the way I've thought about this is like,
- 27:45Speaker 5: are there particular topics where you could reasonably show that
- 27:51Speaker 5: a researcher would have a particular view in mind, and
- 27:54Speaker 5: to see whether or not their studies sort of align
- 27:58Speaker 5: with those views.
- 28:00Speaker 2: You know.
- 28:01Speaker 5: The example that I sometimes tell my undergraduate students is,
- 28:05Speaker 5: you know, think about sort of evidence on masking. There's
- 28:09Speaker 5: not like a ton of studies, and certainly not a
- 28:11Speaker 5: ton of high quality studies on this, But if you
- 28:13Speaker 5: were to see that individuals who published research that showed
- 28:17Speaker 5: that masks are beneficial for the prevention of COVID nineteen
- 28:23Speaker 5: and you look at researchers who found the opposite. If
- 28:26Speaker 5: we looked at those researchers on social media prior to
- 28:29Speaker 5: ever publishing any studies on this topic, would those who
- 28:33Speaker 5: were in the first category be more likely to be
- 28:35Speaker 5: wearing masks, to be tweeting.
- 28:36Speaker 2: About masks things like that.
- 28:38Speaker 5: Like, I think that there are ways to sort of
- 28:40Speaker 5: show that our researchers views about the world. And I
- 28:45Speaker 5: won't even call it ideology because there's no ideology about
- 28:47Speaker 5: coffee and longevity. It's sort of I think it could
- 28:50Speaker 5: be true. There's an incentive for me to publish this,
- 28:53Speaker 5: so I'm going to do it. But thinking about how
- 28:56Speaker 5: the incentives, whether it's career incentives, financial incentives, ideological incentives,
- 29:03Speaker 5: how much the role of incentives play in the questions
- 29:07Speaker 5: that people ask and the way they study them and
- 29:10Speaker 5: the answers that they find. I think is an untapped
- 29:14Speaker 5: area for research, but could be really interesting.
- 29:18Speaker 3: Yeah, And I think, I mean there's so many pieces
- 29:20Speaker 3: of the incentives. There's my personal incentives, there's you know,
- 29:22Speaker 3: how aligned am I with some you know, with an
- 29:25Speaker 3: existing set of beliefs that that other people have. You know,
- 29:29Speaker 3: I think there is some work on like whether it
- 29:31Speaker 3: is you know, how much more difficult it is to
- 29:33Speaker 3: publish something that goes again some existing scientific paradigm, which,
- 29:37Speaker 3: of course, in some ways it should be, because if
- 29:39Speaker 3: you know, everyone says the sky is blue, and you
- 29:41Speaker 3: write a paper that says the sky is green, like, probably.
- 29:45Speaker 1: We shouldn't publish your paper.
- 29:46Speaker 3: But yeah, you know, but that kind of thing in
- 29:50Speaker 3: settings in which is less clear, can can result in
- 29:55Speaker 3: you basically sort of stasis in a in a field
- 29:59Speaker 3: until sort of something surprising happens.
- 30:02Speaker 5: Yeah, you know what conversations I've never had. I've never
- 30:05Speaker 5: asked a journal editor.
- 30:06Speaker 2: Why they publish these studies.
- 30:07Speaker 5: I would love to know the answer that question.
- 30:10Speaker 3: I would love to know the answer to that question too.
- 30:12Speaker 3: I've never managed to find someone to discuss it with me.
- 30:15Speaker 3: I mean, the other thing it's very interesting is probably
- 30:17Speaker 3: like two in the weeds for here, but like an
- 30:21Speaker 3: aspect that's totally so. In economics, like, the peer review
- 30:24Speaker 3: process is very very different than medicine, and economics like,
- 30:26Speaker 3: the peer review process takes an extremely long time, and
- 30:28Speaker 3: there are.
- 30:29Speaker 1: Many people who have means.
- 30:31Speaker 3: It's too extreme in some ways in my view, but
- 30:33Speaker 3: it's you know, you'll have five different people writing you
- 30:35Speaker 3: three pages about how terrible your paper is, and every
- 30:38Speaker 3: single line is the worst. You'll revise and resubmit, and
- 30:41Speaker 3: it's just like a lot of commenting and a lot
- 30:44Speaker 3: of like people reading things in great detail. The referee
- 30:50Speaker 3: process in medicine is much faster, but it also is
- 30:54Speaker 3: way much more about like, here is this paper, do
- 30:58Speaker 3: I like it or not?
- 30:59Speaker 1: More or less as is? And then you know.
- 31:02Speaker 3: That that kind of allows for less space for an
- 31:05Speaker 3: expert reviewer to fix something.
- 31:08Speaker 2: Yeah, yeah, you know, we have this paper.
- 31:12Speaker 5: I'll tell you the finding.
- 31:15Speaker 1: Are you going to tell me the finding of the paper? Now?
- 31:17Speaker 2: I'm going to tell you that.
- 31:17Speaker 5: Oh no, I just I want to tell you another
- 31:19Speaker 5: because it does illustrate some of the things we're talking
- 31:21Speaker 5: about now.
- 31:21Speaker 2: But then I want to do.
- 31:22Speaker 1: That and I want to hear about this.
- 31:23Speaker 5: Yeah, yeah, so we have this paper that shows so
- 31:29Speaker 5: a couple of years ago we had this paper in
- 31:31Speaker 5: the New Aternal Medicine that showed that kids who are
- 31:32Speaker 5: born in August have higher rates of ADHD diagnosis than
- 31:36Speaker 5: kids who were born in September, and the idea was
- 31:38Speaker 5: that in this other economists had shown this as well.
- 31:41Speaker 5: But the idea is that kids were born in August
- 31:43Speaker 5: are often the youngest kids in their class, and so
- 31:46Speaker 5: when they behave differently, that's sort of perceived to be
- 31:49Speaker 5: reflective of ADHD, as opposed to the recognition that these
- 31:52Speaker 5: kids are just younger for their their grade. And that
- 31:56Speaker 5: all stems from the idea that ADHD is a subjective diagnosis.
- 31:59Speaker 5: You don't see the same thing for asthma, you don't
- 32:01Speaker 5: see the same thing for diabetes, because those are more
- 32:04Speaker 5: objectively determined. And now fast forward a couple years later,
- 32:08Speaker 5: we have this paper now which shows that the diagnosis
- 32:13Speaker 5: of ADHD goes up on Halloween. And so we look
- 32:19Speaker 5: at millions of visits to pediatricians on Halloween versus all
- 32:23Speaker 5: the surrounding days. We definitely account for the possiblity that
- 32:28Speaker 5: parents who go to the doctor on Halloween take their
- 32:30Speaker 5: kid there might be different and we show that we
- 32:32Speaker 5: don't think that that's what's going on, and we show
- 32:35Speaker 5: that the diagnosis rate of ADHD is higher, and what
- 32:39Speaker 5: we think is going on is that there are some
- 32:41Speaker 5: children who the provider was thinking about this as a
- 32:45Speaker 5: possibility of a diagnosis ADHD, but they never sort of
- 32:48Speaker 5: pull the trigger on the diagnosis. But on that day,
- 32:52Speaker 5: the behavior the child is different for obvious reasons, right,
- 32:54Speaker 5: Like they're excited about Halloween, right, So they're just less attentive,
- 32:58Speaker 5: they're not answering questions, and so that diagnosis gets made.
- 33:02Speaker 2: It's not a huge.
- 33:02Speaker 5: Effect, but it's it's clearly measurable. You can see it
- 33:05Speaker 5: in the data. And you know, we write this paper
- 33:08Speaker 5: up and we don't know whether this is underdiagnosis or overdiagnosis.
- 33:12Speaker 5: Could be it could be overdiagnosis, right like something as
- 33:15Speaker 5: arbitrary as Halloween leads you to make a diagnosis that
- 33:19Speaker 5: you otherwise wouldn't have made. But it could also be underdiagnosis,
- 33:22Speaker 5: like these children could be. This could be what we
- 33:24Speaker 5: call a stress test, Like you do a cardiac stress
- 33:27Speaker 5: test to look for heart disease. This could be an
- 33:30Speaker 5: ADHD stress test where if that child responds in such
- 33:32Speaker 5: a way on Halloween that you now think about the
- 33:36Speaker 5: diagnosis of ADHD more firmly, that might be indicative of
- 33:39Speaker 5: something that needs to be addressed in that child. So
- 33:42Speaker 5: that could be underdiagnosis. So we write this paper and
- 33:46Speaker 5: we send it to a lot of places, medical journals,
- 33:48Speaker 5: all good places, and you know, most of the reviews
- 33:51Speaker 5: are actually generally like on the methods, they don't have
- 33:54Speaker 5: anything to say. But from a number of places we've
- 33:57Speaker 5: gotten feedback back, both from the editors and from sometimes
- 34:01Speaker 5: reviewers about how this finding is highly stigmatizing to the disease,
- 34:06Speaker 5: and we've had an extraordinarily difficult time to get it published.
- 34:09Speaker 5: Now we're trying going a different route, but you know,
- 34:13Speaker 5: my pushback has been, well, look, you know we're not
- 34:16Speaker 5: calling it. We're not saying that this over diagnoses or
- 34:19Speaker 5: this these are frivolous diagnoses. In fact, if this is
- 34:22Speaker 5: under diagnosis, you know, what does it mean to a
- 34:24Speaker 5: parent that the for their child, the only way that
- 34:28Speaker 5: they would have gotten diagnosed with ADHD is if by
- 34:31Speaker 5: chance they happened to go on Halloween, and otherwise it
- 34:33Speaker 5: wouldn't have been diagnosed with a condition that their child
- 34:36Speaker 5: might have. Like that arbitrariness and the diagnosis I think
- 34:40Speaker 5: should should be concerning to people. It might be inevitable,
- 34:45Speaker 5: but it should certainly be something that flags your attention.
- 34:48Speaker 2: And we've had a really.
- 34:49Speaker 5: Difficult time getting this thing published because, for lack of
- 34:53Speaker 5: better words, what I think are the optics. I mean,
- 34:54Speaker 5: that's what we're that's the feedback that we're getting.
- 34:57Speaker 3: That's very frustrating because, of course, if you sort of
- 35:02Speaker 3: have the very high minded view we're all supposed to
- 35:04Speaker 3: have of science, which is like, we're going to learn things,
- 35:06Speaker 3: and we're going to get data, and then we're going
- 35:07Speaker 3: to use it to make decisions and we're going to
- 35:09Speaker 3: you know, put truth out in the world to sort
- 35:13Speaker 3: of say, well, here's the thing, Like I believe it
- 35:15Speaker 3: to be true, but I feel that people shouldn't hear
- 35:17Speaker 3: it because it will make them feel bad, or it
- 35:20Speaker 3: will you know, the variety of reasons that I that's very.
- 35:24Speaker 1: That must be very frustrating.
- 35:26Speaker 5: It is, but we keep keep watching on. But tell
- 35:29Speaker 5: me when you're ready for this other random finding.
- 35:31Speaker 2: Yes, I'm ready.
- 35:32Speaker 3: Okay, So, so I have one other thing I want
- 35:35Speaker 3: to I want to close this out, and then I
- 35:36Speaker 3: want to hear your random finding.
- 35:37Speaker 1: Okay.
- 35:38Speaker 3: So when I once asked my undergraduate this like sort
- 35:42Speaker 3: of sums up this entire conversation. I once asked my
- 35:44Speaker 3: undergraduate class we had gone through one of these papers
- 35:47Speaker 3: that I was complaining about, and then I asked them
- 35:50Speaker 3: like this sort of question we're have here, just like
- 35:52Speaker 3: sort of whose fault is this? And there was a
- 35:55Speaker 3: kid who kind of thought about it for a while
- 35:57Speaker 3: and then he basically was like, well, I think it's
- 36:01Speaker 3: my fault. And he said, you know, I clicked on
- 36:05Speaker 3: that headline, and that's why they put up the headline,
- 36:08Speaker 3: and that's why the person wrote the story, and that's
- 36:11Speaker 3: why the journal took the article, and that's why the
- 36:13Speaker 3: researcher wrote the article so the journal would take it,
- 36:17Speaker 3: and the journal took it so the guy would write
- 36:19Speaker 3: about it, and the person wrote about it because they
- 36:21Speaker 3: knew it would get a good headline, and they put
- 36:23Speaker 3: the headline on so I would click on it, and
- 36:26Speaker 3: so this is my fault. And I was like, yeah,
- 36:28Speaker 3: I guess it is. It's like, thank you for the lesson.
- 36:33Speaker 3: So that's why twenty year olds are smart.
- 36:36Speaker 2: Yeah, that's almost like reader shaming. I don't know. I wouldn't.
- 36:39Speaker 2: I don't think it's his fault. I don't think it's
- 36:43Speaker 2: his fault at all.
- 36:50Speaker 3: More parenting it including the importance of debunking panic headlines
- 36:55Speaker 3: for the sake of parents' mental health, and we finally
- 36:58Speaker 3: get to Bapu's groundbreaking research after the break, just to
- 37:15Speaker 3: sort of close it because it's a parenting podcast. I
- 37:18Speaker 3: think that so much of what I spend my time
- 37:22Speaker 3: doing is sort of dialing down people's panic around these
- 37:26Speaker 3: kind of headlines which come up all the time in parenting.
- 37:28Speaker 1: Because if you had to.
- 37:30Speaker 3: Pick a space in the world to write panicky headlines,
- 37:34Speaker 3: parenting would be it, because that's really what people like
- 37:37Speaker 3: to click and I guess just to like not to
- 37:40Speaker 3: put too fine a point on it, but I think
- 37:43Speaker 3: actually in the parenting space it can be quite bad
- 37:47Speaker 3: in the sense of, you know, we talk about this,
- 37:49Speaker 3: you and I talk about this like oh, like of
- 37:51Speaker 3: course nobody thinks that this is true, and like, you know,
- 37:54Speaker 3: researchers know it's not.
- 37:55Speaker 1: But here's why.
- 37:55Speaker 3: Here's the sort of interesting academic thing. But I think
- 37:58Speaker 3: for many people who who click on these adlines, who
- 38:01Speaker 3: see them, actually it does make them feel really bad,
- 38:06Speaker 3: and it does make them worry about behaviors which are
- 38:10Speaker 3: which they're already taking. You know, I let my kid
- 38:12Speaker 3: watch a screen and is it my fault that you know?
- 38:15Speaker 1: They have ADHD?
- 38:16Speaker 3: It's such a common question, and so it's not free
- 38:20Speaker 3: these things. This is not just an academic debate once
- 38:22Speaker 3: it gets out into the world.
- 38:25Speaker 5: So your your statement makes me think of a like
- 38:29Speaker 5: a research question, which is, you know, I think the
- 38:33Speaker 5: journals and the people who write these articles probably view
- 38:35Speaker 5: these articles as being costless, meaning that there's no cost
- 38:39Speaker 5: imposed on society from generating this kind of knowledge. But
- 38:42Speaker 5: what if you did a study where you showed that
- 38:46Speaker 5: if there is a paper that comes out that shows
- 38:49Speaker 5: some purported link between autism or ADHD or something, you know,
- 38:56Speaker 5: where we don't have a good firm understanding of what's
- 38:57Speaker 5: causing it, and it links it to a very common
- 39:00Speaker 5: behavior or common thing that people might do. I wonder
- 39:05Speaker 5: if you see, like in the weeks or months following that,
- 39:08Speaker 5: you see you know, increased diagnoses of anxiety or depression,
- 39:15Speaker 5: or increased prescription fills among mothers versus of young children
- 39:20Speaker 5: who have that condition versus mothers of young children who
- 39:23Speaker 5: do not have that condition, or something like that. You
- 39:25Speaker 5: have to find something that was really splashy that got
- 39:27Speaker 5: people like, oh my goodness, could this possibly be true?
- 39:31Speaker 5: But if your sort of hypothesis is right, which I
- 39:34Speaker 5: totally think it is. I mean, you see studies like
- 39:36Speaker 5: this and you think, oh, what did I do wrong?
- 39:38Speaker 5: You didn't want to do anything wrong? Yeah, what I
- 39:40Speaker 5: do wrong? It's a paralyzing feeling, I think for a parent.
- 39:44Speaker 5: So it would be great to do that, to show
- 39:46Speaker 5: that these studies have impact. It's not you know, maybe
- 39:49Speaker 5: coffee and you know, heart attacks is not a good
- 39:53Speaker 5: one because no one's really going to feel bad, but
- 39:54Speaker 5: they're probably.
- 39:56Speaker 3: Tail and all and autism Thailand. I mean, it's like
- 39:59Speaker 3: a bunch of these things where I hear about them
- 40:01Speaker 3: a lot.
- 40:03Speaker 2: Or vaccine related things. Yeah, you know, like you know,
- 40:06Speaker 2: you know what you know?
- 40:07Speaker 5: What is the cause of effect of vaccines on various
- 40:09Speaker 5: different or COVID nineteen vaccine of various different outcomes? If
- 40:12Speaker 5: your child had some outcome and you ascribed it to
- 40:15Speaker 5: a vaccine, your view of vaccines might be different. Your
- 40:20Speaker 5: views of the federal government might be different after that,
- 40:23Speaker 5: for reasons that were sort of totally unfounded and would
- 40:27Speaker 5: never have entered your mind had that kind of study
- 40:29Speaker 5: not been published.
- 40:32Speaker 1: Okay, to close, can you please tell us your result.
- 40:34Speaker 1: I'm dying.
- 40:35Speaker 5: Wow, Now I kind of feel bad because you're going
- 40:37Speaker 5: to see there's a link between what I literally just
- 40:39Speaker 5: said and what I'm about to say.
- 40:41Speaker 2: All right, but that's life, all right, So let me
- 40:44Speaker 2: just frame it about it.
- 40:45Speaker 5: There was a study I don't know, maybe ten years ago,
- 40:49Speaker 5: a long time ago, which looked at taxi cab drivers
- 40:52Speaker 5: in London and it showed that a particular part of
- 40:58Speaker 5: the brain called the hippocampus is enlarged in an enhancing
- 41:04Speaker 5: way in these drivers. And the reason why is because
- 41:07Speaker 5: they had to memorize all these streets they're driving around.
- 41:09Speaker 5: There is actually a test that they had to take
- 41:11Speaker 5: called the Knowledge and the idea was that because of
- 41:13Speaker 5: the hippocampus is involved in spatial processing and spatial recognition,
- 41:19Speaker 5: that that part of the brain becomes stronger, for lack
- 41:22Speaker 5: of better words, just like if you exercise certain parts
- 41:24Speaker 5: of your body, they'll become stronger. Same intuition. The hippocampus
- 41:28Speaker 5: has also been implicated in Alzheimer's disease. Now the study
- 41:33Speaker 5: that's coming out and it's coming out in the British
- 41:36Speaker 5: Medical Journal in a.
- 41:36Speaker 2: Couple of weeks.
- 41:38Speaker 5: We use this data that you're probably familiar with, where
- 41:41Speaker 5: death certificates in the United States have recently been linked
- 41:44Speaker 5: to occupation. So we're looking at these data and what
- 41:47Speaker 5: kind of questions can we answer? And I think about
- 41:50Speaker 5: this study in London taxicab drivers a long time ago,
- 41:55Speaker 5: and I'm like, well, I wonder what if we look
- 41:57Speaker 5: at taxicab drivers in the United States. What is you know,
- 42:01Speaker 5: what do rates of Alzheimer's dementia look like in taxicab
- 42:04Speaker 5: drivers as a cause of death compared to every other occupation.
- 42:08Speaker 5: And so we look at something like four hundred and
- 42:10Speaker 5: fifty occupations, and taxicab drivers and ambulance drivers not like EMTs,
- 42:16Speaker 5: but ambulance drivers who are just literally doing the same thing.
- 42:19Speaker 5: They have to drive all different places, they don't know
- 42:21Speaker 5: where they're going, they have to memorize these roads. They
- 42:24Speaker 5: have the two lowest rates of Alzheimer's related dementia contributing
- 42:28Speaker 5: to mortality than all other occupations, and we show that
- 42:34Speaker 5: they have No, they're not lower in terms of other
- 42:37Speaker 5: forms of dementia that are not thought to be related
- 42:39Speaker 5: to sort of hippocampus or what we call Alzheimer's disease.
- 42:43Speaker 5: And so it's a very strange finding. And of course
- 42:47Speaker 5: we're not going to come out and say you should
- 42:50Speaker 5: become a taxi cab driver. We're not going to come
- 42:52Speaker 5: out and say you should stop using Google Maps.
- 42:55Speaker 3: I think the headline here is is, like, you know,
- 42:58Speaker 3: using Google Maps dementia.
- 43:01Speaker 1: That's the headline I would go with.
- 43:02Speaker 5: And I've already shortaged stocks for Google or alphabet whatever.
- 43:05Speaker 2: It's called an anticipation of this.
- 43:07Speaker 5: But like you know, we literally one of the last
- 43:09Speaker 5: lines to say is you know, we view this as
- 43:12Speaker 5: just generating a hypothesis. It's an idea. Think more about
- 43:16Speaker 5: how you might study this in a more causal way.
- 43:19Speaker 2: We don't.
- 43:19Speaker 5: We're not arguing that this is causal. We're not using
- 43:22Speaker 5: causal language. We're just saying it's an idea, a really
- 43:26Speaker 5: strange idea. And so I think that, like there is
- 43:29Speaker 5: space for correlational studies that are a answering interesting questions that
- 43:35Speaker 5: have not been already published on fifty times before in
- 43:38Speaker 5: the last two years. So there is space for those
- 43:40Speaker 5: studies if they're a answering or looking for interesting relationships
- 43:45Speaker 5: that haven't previously been studied, and b not claiming more
- 43:50Speaker 5: than what they're claiming and saying, look, here's what here's
- 43:52Speaker 5: what it makes us think about, here's how we should
- 43:55Speaker 5: look at this further. I think those kinds of things
- 43:57Speaker 5: are useful.
- 43:57Speaker 3: Yeah, And I think from this there's like a million
- 44:00Speaker 3: sort of quite interesting studies one could think about doing
- 44:03Speaker 3: that would dial more into causality.
- 44:06Speaker 1: Like the thing the obvious thing that comes to mind.
- 44:07Speaker 3: For me is, you know, randomly in like basically fMRI,
- 44:13Speaker 3: put people in an fMRI machine and then you know,
- 44:16Speaker 3: have them do two months in which they do some
- 44:19Speaker 3: training on you know, different kinds of maps and sort
- 44:23Speaker 3: of like linking this to some of these this research
- 44:25Speaker 3: questions around you know, can we encourage people to stay
- 44:28Speaker 3: undamented by like pushing their brain in various ways?
- 44:32Speaker 5: Yeah, yeah, looking at that and then maybe doing memory
- 44:34Speaker 5: assessments of these individuals. I mean, there's all sorts of
- 44:37Speaker 5: ways that you could do this, and to be honest,
- 44:40Speaker 5: probably none of them would work, but that that's totally fine.
- 44:43Speaker 5: But it's just sort of at least it's a different
- 44:46Speaker 5: idea than what we see.
- 44:51Speaker 1: I love it, Thank you, Bapu. I really love having you.
- 44:55Speaker 2: I love being here. Thank you. It feels like just yes, sir.
- 45:11Speaker 3: Parent Data is produced by Tamar Avishai with support from
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- 45:38Speaker 3: I'd encourage you to go to our website and just
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