1081-Microbial Single-Cell Omics In Situ
Researchers have developed a new method called Laser-Induced Forward Transfer (LIFT) to perform high-quality single-cell genomics and transcriptomics on microbes within their natural environments. This technique allows for the precise isolation of individual bacteria from complex samples, such as human saliva, mouse gut tissues, and cancerous tumors, using automated imaging and Raman spectral fingerprints. By bypassing the limitations of traditional microfluidics, the study successfully mapped cell-fate commitment during bacterial sporulation and identified specific metabolic activities in…
The skinny
The skinny isn't ready yet — notes appear once the transcript is processed.