Pharma 39: Histamine and Bradykinin - Vessels, Leakage, and Alarm

Clinical Deep Dives · Feb 2, 2026 · 1m

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This episode examines histamine and bradykinin as first-response mediators—fast, local signals that change vascular tone, permeability, and sensation almost instantly. We explore why these systems are indispensable for defence yet prone to excess, and how antagonists work not by silencing immunity but by restoring proportion. Seeing histamine and bradyk…