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Polygenic risk scores – The Truth in our Genes
The biorevolution podcast #22
Polygenic risk scores (PRS), put simply, look at gene variants across the human genome in order to determine an individual's risk of getting a disease, from different types of cancer to type II diabetes. PRS could complement current risk prediction models and lead to a more accurate risk prediction. However, for PRS to become a useful clinical instrument, transparent ways to assess their performance and careful communication of disease risks to individuals are key. In episode 22 of We’re doomed we’re saved, Andreas Horchler and Louise von Stechow speak to two PRS…
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