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419: Immune Firepower & Hormones: Understanding Gender‑Linked Autoimmune Disease - XX & XY Chomosomes!
Hormones, Chromosomes & Immunity — The Hidden Gender Divide* Autoimmune diseases behave differently in XX and XY bodies. Women’s immune systems are wired to be stronger but more reactive because two X chromosomes carry multiple immune‑regulating genes, while men’s single X and Y chromosomes produce a calmer, more suppressed immune profile. Hormonal shifts through puberty, pregnancy, menopause, and menstrual cycles amplify these differences — oestrogen stimulates immune activity, progesterone calms it, and testosterone suppresses inflammation. This explains why conditions such as lupus…
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