055-The brain-immune code
This comprehensive review explores the evolving understanding of the central nervous system (CNS) and its intricate relationship with the immune system, challenging the long-held concept of CNS immune privilege. It highlights the crucial roles of the glymphatic system, which clears waste from the brain, and meningeal lymphatic vessels, which drain antigens to the periphery, in maintaining brain-immune dialogue. The text further discusses how inflammation, aging, and neurodegenerative diseases like Alzheimer's disrupt this delicate balance, leading to an "altered immune code" that can…
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