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Why Swiss Skincare is Setting the Standard for Skin Health with Cellcosmet · Skin Anarchy

• 0:00
  SPEAKER_02: Hey guys, welcome back to another episode of Skin Anarchy.
• 0:03
  SPEAKER_02: I am really excited to introduce you guys to a new brand today that I have fallen in love with.
• 0:08
  SPEAKER_02: Um, you know, as you know, we're always looking for very science-backed solutions here at Skin Anarchy.
• 0:14
  SPEAKER_02: Many of you chime in with wanting recommendations, wanting new options for your skin health.
• 0:19
  SPEAKER_02: And I feel like the brand we're gonna be um talking about today is really kind of focusing right there, you know, in terms of the whole skill health skin health component um when we talk about skincare.
• 0:30
  SPEAKER_02: So without further ado, I want to introduce you guys um to the chief scientific officer and the um the general manager North America of Sol Cosmet.
• 0:41
  SPEAKER_02: Uh so without further ado, let me introduce Dr.
• 0:43
  SPEAKER_02: Jeremy Sawyer and uh Jennifer Hassel.
• 0:46
  SPEAKER_02: Welcome to the show.
• 0:47
  SPEAKER_01: Thank you so much for having us.
• 0:48
  SPEAKER_01: We're really excited to be here.
• 0:50
  SPEAKER_02: Yeah, I'm excited to have you.
• 0:53
  SPEAKER_00: Thank you for the invitation.
• 0:55
  SPEAKER_00: Yeah.
• 0:55
  SPEAKER_02: Yeah, Dr.
• 0:56
  SPEAKER_02: Sawyer, I'm excited to kind of uh pick your brain a little bit, you know, on the show because I feel you have a background in cellular and molecular biology.
• 1:05
  SPEAKER_02: And, you know, back in when I was in in college, all of my professors that were, you know, of similar background, it was like talking to the most intelligent people on the planet.
• 1:14
  SPEAKER_02: So, you know, you're gonna get a lot of questions from me, you know, about clarifications.
• 1:18
  SPEAKER_02: But I'd love to get started if if we could talk about Dr.
• 1:20
  SPEAKER_02: Sherry, what made you want to get involved with this brand and and really um what what is uh Cell Cosmet's vision when it comes to skincare?
• 1:29
  SPEAKER_00: Yeah, absolutely.
• 1:30
  SPEAKER_00: So once again, thank you for the invitation.
• 1:32
  SPEAKER_00: I'm so happy to to talk with you about the the the brand and science behind Cell Cosmetics.
• 1:36
  SPEAKER_00: So Cell Cosmet's vision is rivaled by the belief that science is both a key driver of innovation and rigorous essential method to guarantee and prove that quality and efficacy of a product.
• 1:49
  SPEAKER_00: And four years ago, when I talked with Stancred, or CEO, I immediately connected with vision because I firmly believe that science, scientific method, is one of the best ways to address the current crisis of the trust, you know, everywhere in the society, in science, in beauty industry.
• 2:10
  SPEAKER_00: Many brands promise impressive results without providing solid scientific proof.
• 2:16
  SPEAKER_00: And finally, it is the sense of purpose of Celcosmet who claim behind each claim we have a rigorous, robust uh sciences efficacy claim.
• 2:28
  SPEAKER_00: You know, for example, we are claiming that our last uh generation of product are preserving skin microbiome.
• 2:38
  SPEAKER_00: Several brains are guaranteed or claim uh microbium-friendly and assume or support this claim within vitro studio study, only in Petrich dish completely disconnected with the real time.
• 2:54
  SPEAKER_00: In our situation, when we claim that we preserve and we strengthen skin microbiome, we perform clinical studies.
• 3:02
  SPEAKER_00: That means for each volunteer of the clinical study, we we we sequences each bacteria living on the skin of the people, and before and after, we measure the percentage of each bacteria and what we will be able that we we maintain and we strengthen the right and good uh microbiome.
• 3:24
  SPEAKER_00: It's just an example to explain why I may I may be the most lucky chief science of cosmetic brand because I have an opportunity to spend a lot of money to prove the efficacy of food product.
• 3:39
  SPEAKER_02: That's amazing.
• 3:40
  SPEAKER_02: I love what you said because I think that that's one of the biggest, biggest misunderstandings that I've seen, because my the microbiome became a buzzword, you know, at some point, I think a few years ago in this industry.
• 3:53
  SPEAKER_02: And exactly what you said, when you're looking in in a petri dish at bacteria and the way they grow, the way they interact, it's incredibly different than the way they are going to act on actual human tissue.
• 4:06
  SPEAKER_02: You know, that's a very, very different scenario.
• 4:08
  SPEAKER_02: And so I just from the get-go that you've mentioned this is wonderful, you know, because very few brands talk about this very relevant piece of information.
• 4:19
  SPEAKER_02: And, you know, if you're gonna if you're gonna market something to say that this is a microbiome related product, you know what I mean, and it's meant for skin health and it's meant to actually fix the dysbiosis going on, you know, that's ruining your skin barrier, you have to actually try it on people, you know, you have to actually have studies.
• 4:37
  SPEAKER_02: So I agree with you.
• 4:38
  SPEAKER_02: But um, Jennifer, I would love to for you to chime in because I know you have so much experience in this industry.
• 4:42
  SPEAKER_02: I mean, what was it like for you to get involved with with the brand and you know, um what they were doing?
• 4:48
  SPEAKER_02: I mean, what are your thoughts on on this whole topic of the microbiome?
• 4:52
  SPEAKER_01: Oh, absolutely.
• 4:53
  SPEAKER_01: So um I actually, when I met uh Tankerd is a CEO as well as the chairman, um, I actually knew this brand from my esthetician.
• 5:02
  SPEAKER_01: So when I used to go, obviously same esthetician today almost, um, but I discovered Cell Cosmet a long time ago and was impressed by the product.
• 5:12
  SPEAKER_01: So when I was introduced to the brand, um, I was really excited to get involved in a brand that really held the science at the forefront of the products that they produced and have been doing it for decades.
• 5:24
  SPEAKER_01: So it wasn't about kind of jumping on um a trend, it was really about the belief that we could care for the health of our skin in a much more positive aging process by constantly revitalizing, right?
• 5:39
  SPEAKER_01: Constantly working at the cellular level to um help us age gracefully, right?
• 5:44
  SPEAKER_01: Um, and so for me, that was what was really exciting.
• 5:47
  SPEAKER_01: And then when the introduction with the um process and the technology that they used with the ingredients before the microbiome, and understanding that not only, yes, these are the ingredients, yes, they are um extremely kind of strong ingredients that will work to protect the microbiome, but we proved it out that as we age, right, it becomes more and more fragile.
• 6:12
  SPEAKER_01: And the fact that the good bacteria that we're losing, we're actually proving that we're actually getting it back when these ingredients are applied to our skin.
• 6:22
  SPEAKER_01: So I think every day I spend time with with Jeremy and I constantly learn about how we can improve from a scientific level and scientific testing of what ingredients are truly from a holistic standpoint in our formulas going to make a difference in our skin.
• 6:38
  SPEAKER_02: That's wonderful.
• 6:39
  SPEAKER_02: I love that.
• 6:39
  SPEAKER_02: And I love that you guys are really approaching the microbiome with this with this fresh perspective, I think, you know, that we haven't really seen in the industry.
• 6:47
  SPEAKER_02: You know, Dr.
• 6:48
  SPEAKER_02: Sawyer, I'd love for you to dive in deeper for us to understand the technologies that are that have been developed and that are being used in the products uh that you know with that cell cosmet has in its lineup.
• 7:00
  SPEAKER_02: Um can you tell us a little bit about the technology portion?
• 7:04
  SPEAKER_00: So let's start by cell control metal, for example.
• 7:08
  SPEAKER_00: So maybe before to deep dive on the on or exclusive and owner proprietary uh technology, let's explain some biochemistry information, you know, basic biochemistry of protein and peptide, because you know your your cytope, the main uh innovative technology uh are a huge uh cocktail of protein and peptide.
• 7:34
  SPEAKER_00: But let's explain why cell control method is was and is still a disruptive method.
• 7:42
  SPEAKER_00: You know, peptide and protein are made of of small building block called amino acid.
• 7:48
  SPEAKER_00: And it is this amino acid assembled with a huge and complex structure forming 3D shape which bring the activity.
• 7:58
  SPEAKER_00: Uh if you heat, if you remove the water of the environment of protein and peptide, you completely lost the the the activity of protein and peptide.
• 8:11
  SPEAKER_00: Uh it's it's really clear.
• 8:13
  SPEAKER_00: For example, if you put uh ROS factor EGF, he is able to activate some specific receptor.
• 8:22
  SPEAKER_00: If you disrupt the the structure of EGF, you completely lost the activity.
• 8:29
  SPEAKER_00: Finally, the cell crosswall method cell control method is a method which guarantees and preserves the 3D structure and so the activity of protein and peptide during the industrial uh process.
• 8:44
  SPEAKER_00: You know, it's it's really important you keep in mind that in cosmetic product protein and peptide are often designated, you know, to simplify manufacturing process to extend the safe life.
• 8:58
  SPEAKER_00: In our situation where cytopeps uh complex peptide and protein are still in water in the natural environment in order to keep the huge activity from the laboratory up to the final product uh you applied every day in the bath.
• 9:17
  SPEAKER_00: Yeah, it's it's it's really a huge, huge uh technological and and manufacturing challenge.
• 9:24
  SPEAKER_00: You know, uh each day my operation chief asks me if I can simplify the process, you know, uh, because it's a nightmare for the the manufacturing.
• 9:34
  SPEAKER_00: But to be sure to keep the the the best activity as possible, we developed this method.
• 9:41
  SPEAKER_00: But behind this cell control method, there is another characteristic because the protein and peptide come from cells, and you know, cellular environment is liquid and crowded, you know.
• 9:55
  SPEAKER_00: Cells, it's not an empty environment.
• 9:58
  SPEAKER_00: There is sugar, protein, peptide, it's a crowded environment.
• 10:02
  SPEAKER_00: And if you are not able to recreate the croded environment, you there is a huge risk to keep the structure of protein.
• 10:10
  SPEAKER_00: So in cell control method, there is some secret ingredients that we had uh we had we put in the in the specific step of the formulation to keep to maintain to mimic the the crowded environment, natural crowded environment, once again to keep the the 3D structure and to to amplify the activity of uh of protein.
• 10:35
  SPEAKER_02: Wow, that's really really fascinating.
• 10:37
  SPEAKER_02: I've you know, and I think that's something that it's never really talked about at all is this idea that there is a crowded, yeah, inside of every cell, it's very, very crowded.
• 10:47
  SPEAKER_02: And um everything has its place, you know, and everything's going where it's going for a reason.
• 10:52
  SPEAKER_02: And and that's a that's very interesting when I look at that, you know, bringing that whole system out in, you know, in the way that we're now talking about putting it in a formula and then, you know, making it available.
• 11:04
  SPEAKER_02: I mean, the bioavailability, for example, is a topic nobody speaks about, you know, but then with that also comes these components that you're talking about, which is that a peptide isn't always the same thing, you know.
• 11:16
  SPEAKER_02: A peptide if it's if it loses its functionality, like you said, if even one amino acid acid is messed up or lost, you know, you've completely lost the ability to bind with the receptor and you know, and to what works.
• 11:28
  SPEAKER_02: So I mean, it these are very fundamental scientific topics that unfortunately, you know, I think a lot of consumers believe that all peptides are the same, and this is why it's so important.
• 11:40
  SPEAKER_02: Yeah.
• 11:41
  SPEAKER_00: Yeah, and let me take the link with our own technology, Cytopep.
• 11:46
  SPEAKER_00: You know, Cytope, just the the name is Cyto in Greek mean cells, uh, in last Greek it means a pep for peptide.
• 11:54
  SPEAKER_00: And finally, our cytope is a huge complex cocktail of protein, peptide, amino acid, and enzyme, much more 5,000 different peptides and protein.
• 12:05
  SPEAKER_00: This is why it's absolutely uh an evidence for me to keep in good environment because we have so huge difference specificity with the protein and peptide.
• 12:18
  SPEAKER_00: And in fact, why we choose to capitalize on the protein and peptide, you know, DNA is the code of the life.
• 12:26
  SPEAKER_00: Protein and peptides are the motor of the life.
• 12:30
  SPEAKER_00: That's why our technology capitalized on the holistic activity of protein and peptides, and finally, uh, the great diversity of the protein, once again, much more 5,000, is the the the guarantee that you'd address, you'd activate several lots of different pathways in in the skin, you know.
• 12:51
  SPEAKER_00: And and finally, uh for me it's an evidence because aging is a multifactorial process.
• 12:58
  SPEAKER_00: There is not only one pathway involved in the in the edging.
• 13:03
  SPEAKER_00: Uh between intrinsic factor, extrinsic factor, there is uh imbalance of oxidative stress, some transcription factor are uh activited, another one as are under or regulated.
• 13:17
  SPEAKER_00: That's why for me to have a huge diversity of protein and peptide is the guarantee to stimulate to have a better anti-aging activity.
• 13:29
  SPEAKER_02: Yeah, no, that makes a lot of sense actually, because at the end of the day, I like I like what you said that you know aging is a multifactorial thing.
• 13:36
  SPEAKER_02: And especially when you look at it from the biology standpoint or physiology standpoint, I think one of the biggest um pitfalls for consumers is this idea that you know, if I just buy something that, for example, look at growth factors, right?
• 13:50
  SPEAKER_02: People think if I buy a serum that is packed with growth factors, it's going to work on my skin.
• 13:56
  SPEAKER_02: But what happens?
• 13:58
  SPEAKER_02: Instead of working, it causes inflammation because none of those things are you know optimized.
• 14:04
  SPEAKER_02: None of those uh proteins that you're working with are actually optimized to work with your skin's normal physiology.
• 14:10
  SPEAKER_02: So what you end up doing is putting a lot of um, you know, probably poorly manufactured, you know, bioproducts all over your skin and eliciting this immune reaction, right?
• 14:22
  SPEAKER_02: So that's where I feel like it's very, very important for consumers to understand that there is a very specific science behind anything that is meant to interact with your skin or its receptors or any of the proteins or anything that's found on the surface, you know, that's very specific and it's a very meticulous process to be able to understand that as well.
• 14:43
  SPEAKER_02: I mean, everybody's microbiome is different.
• 14:46
  SPEAKER_02: So we have to understand what species exist in what concentrations, and then understand what do they need.
• 14:55
  SPEAKER_02: So, based off that understanding, can you talk to us a little bit about the microbiome and educate us, you know, about this?
• 15:02
  SPEAKER_02: So we understand what we should be expecting.
• 15:04
  SPEAKER_02: You know, if we're looking for a support for a microbiome-based product, what should we be expecting?
• 15:11
  SPEAKER_00: Yeah, yeah, absolutely.
• 15:12
  SPEAKER_00: Yeah.
• 15:13
  SPEAKER_00: And yeah, so regarding the microbiome territory, it's just an amazing revolution for me in medical, in skincare, because we just learned that uh finally in in quantity and in terms of number of bacteria living on the skin, it's quite just below of the bacteria of the gut.
• 15:32
  SPEAKER_00: So that's mean it's in quantity and quality, um, skin microbiome is absolutely important for us for the skin quality.
• 15:41
  SPEAKER_00: Uh sorry, do you want to add something, Jennifer?
• 15:44
  SPEAKER_01: No, no, no, but I just think, I mean, actually, I'm learning, right?
• 15:46
  SPEAKER_01: I mean, I didn't realize that it actually had the same volume that your gut bacteria has.
• 15:51
  SPEAKER_01: So to me, I mean, I don't think people um assimilate the two.
• 15:54
  SPEAKER_01: I'm sure maybe a lot of of your listeners do, but I think it's really um important to understand that the impact of how being able to manage and um help control and protect that microbiome on your skin really does impact how your screen your skin reacts every single day.
• 16:12
  SPEAKER_01: Yeah.
• 16:13
  SPEAKER_00: Yeah, yeah.
• 16:14
  SPEAKER_00: And what it is really interesting because it's uh finally there is several link in the the clinical study we performed 10 years ago uh aiming to decipher the impact of popu of uh of pollution, we finally we we understood that pollution could modify uh directly uh skin quality for sure, but modify as well the skin bacteria.
• 16:41
  SPEAKER_00: And finally, and you're absolutely right, Dr.
• 16:44
  SPEAKER_00: Edka's, the each skin microbiome are unique.
• 16:49
  SPEAKER_00: And thanks to new technology, huge uh big data AI sequence technology, we are able to follow to quantify more and more different bacteria living on the skin, and to predict uh some skin events.
• 17:06
  SPEAKER_00: And what what we learned and what we published two years ago is that there is a specific bacteria signature we could predict the the appearance of skin disorder in environment, uh in polluted environment.
• 17:23
  SPEAKER_00: And you know, for me it's it's why I'm really lucky to be there because we are absolutely convinced that the next skincare generation are the personalized generation, the product, but before the product is to be able to offer the best uh skin diagnosis, holistic diagnosis.
• 17:40
  SPEAKER_00: That means in the future, I would like to be able to develop my product according to the skin microbiome sequencing, according to exposure measurement.
• 17:51
  SPEAKER_00: We are able to measure the pollutants which are exposed every day by just a sampling of uh several air fibers.
• 18:00
  SPEAKER_00: We are able to predict and to measure the physiological age with the epigenetic markers, and for me it's really fantastic.
• 18:09
  SPEAKER_00: It's it's so so interesting period regarding the science and what we have in terms of opportunity to develop the product.
• 18:17
  SPEAKER_02: Absolutely.
• 18:17
  SPEAKER_02: Yeah, no, it's it's like the you know, the sky is the limit, I think, with this topic because there's so much that we don't know.
• 18:24
  SPEAKER_02: And you know, Jennifer, talking about like the gut and the skin that Dr.
• 18:28
  SPEAKER_02: Sawyer mentioned, I agree with you.
• 18:30
  SPEAKER_02: I feel like for consumers, it's a very big learning curve, right?
• 18:34
  SPEAKER_02: Because like we we don't really understand that the gut microbiome, like you know, we think of the gut as like superpopulated, but everything kind of mimics that.
• 18:44
  SPEAKER_02: I mean, at the end of the day, I when I when I first started learning about these products, I mean, microbiome came on the scene.
• 18:50
  SPEAKER_02: It was almost as if, like, you know, you're now trying to understand that bacteria play a much bigger role than just like what we know about with digestion and what there's this whole like gut skin access and like gut brain axis, and there's all these different things.
• 19:04
  SPEAKER_02: So I would love to get your perspective here because you have so much, you know, experience, like you've seen so many brands and you've seen the industry evolve.
• 19:11
  SPEAKER_02: How do you think, you know, this is going to like with everything cell cosmic is doing and also what's being propagated in the industry?
• 19:19
  SPEAKER_02: Like, how do you think the microbiome really fits in to overall, you know, beauty and wellness in the industry?
• 19:25
  SPEAKER_01: Yeah, personally, I've kind of gone down this journey.
• 19:28
  SPEAKER_01: So, kind of both personally and professionally, I started looking at the gut health.
• 19:32
  SPEAKER_01: So I actually was at Vivemeyer many years ago.
• 19:37
  SPEAKER_01: Um, and I really wanted to understand how stress, what I was eating, what was happening in my life, how my skin was reacting, how my hair was reacting, that I couldn't seem to get a handle on it until kind of stepped away to figure out how truly all the interconnections of our body, and we know, right?
• 19:59
  SPEAKER_01: We know our body is all interconnected, but I think we as an average consumer, we don't think about that every day.
• 20:05
  SPEAKER_01: And when we started to change what was going on in our diet, um, what was happening with how our body was processing, and you know, I'm always open up, I I have a thyroid issue, it slows down.
• 20:17
  SPEAKER_01: Well, when I when I spent the time to fix basically my gut health and my diet, my thyroid started working all by itself again, right?
• 20:26
  SPEAKER_01: And then my skin was brightening up and my hair was getting more stronger.
• 20:32
  SPEAKER_01: And I started to see all of these correlations just as an individual, and then I look at the business that we're in and the fact that we need more education about the science of how we're going to take care of our skin health, and I'll say our hair health, and overall, obviously, our gut health, so that we can make a difference and the microbiome are all interrelated.
• 20:56
  SPEAKER_01: And you know, I I always defer back to the scientists is how can you help us better understand how we can make an impact when we were in the test for our um the postbiotic complex, right?
• 21:10
  SPEAKER_01: The three marine ferments of our uh of our product.
• 21:14
  SPEAKER_01: And the fact that we didn't even know about PCR tests until COVID, right?
• 21:18
  SPEAKER_01: We, as a consumer, didn't.
• 21:20
  SPEAKER_01: And when we ran the PCR tests, I didn't realize that we were losing all of our good bacteria as we were aging.
• 21:27
  SPEAKER_01: We just knew that we had lots of different bacteria in our skin.
• 21:30
  SPEAKER_01: But there were there are good forces at work, and we need to make sure that we're protecting them as we age and make sure that we're increasing them, if at all possible, between protecting against the exposomes as well as what we're actually putting into our bodies.
• 21:45
  SPEAKER_01: So it really is this holistic story that I think we all have to get stronger at telling, and very specifically when we're talking about skincare, how do we help our consumers?
• 22:00
  SPEAKER_01: Our family, our friends actually make those decisions to protect the health of their skin.
• 22:05
  SPEAKER_01: Because in the end, right, it's all about the longevity of the health of our skin, no matter how we choose to care for ourselves.
• 22:13
  SPEAKER_02: Right.
• 22:13
  SPEAKER_02: Does that make sense?
• 22:14
  SPEAKER_02: Yeah, absolutely.
• 22:15
  SPEAKER_02: You know, I completely agree.
• 22:17
  SPEAKER_02: And I think that that's very, it's very, very important because I think, especially with, you know, this whole anti-aging conversation, that's the most relevant piece, is that we are changing when we age.
• 22:28
  SPEAKER_02: I mean, it's the biggest part about it.
• 22:30
  SPEAKER_02: I mean, I think people have this terrible way of like kind of portraying anti-aging in the industry where they're always talking about like things like wrinkles and snagging and all this, but no one's really discussing what you brought up just now.
• 22:41
  SPEAKER_02: You know, it's like you your body is changing.
• 22:43
  SPEAKER_02: The your the bacteria on your skin are changing, you know, the different concentrations of things are changing.
• 22:48
  SPEAKER_02: I mean, all of these things have to be accounted for just to have a healthier life.
• 22:53
  SPEAKER_02: So yeah, I I agree.
• 22:54
  SPEAKER_02: And I think that's a very strong pillar, you know, that I would love to see more amplified in our industry is this idea of like health before anything else, you know.
• 23:03
  SPEAKER_01: Yep, yeah.
• 23:04
  SPEAKER_01: I agree with you.
• 23:04
  SPEAKER_01: And you know, one of the I think what you you asked in the beginning about, you know, why did I join Xel Cosmet?
• 23:11
  SPEAKER_01: And um it was fascinating to me is when I started using the products.
• 23:16
  SPEAKER_01: I came, I came back from Switzerland and two weeks later, maybe two or three weeks later, people started complimenting on me on my skin.
• 23:25
  SPEAKER_01: Now, I've been using beautiful products, right?
• 23:28
  SPEAKER_01: Most of my my career at least.
• 23:32
  SPEAKER_01: And people just would cut, your skin looks great, it looks, it's glowing, it looks healthy.
• 23:37
  SPEAKER_01: Like I made all of these kind of contacts to someone that's in an industry.
• 23:42
  SPEAKER_01: And then when I would share this experience with other people, I said, just wait, don't say anything.
• 23:48
  SPEAKER_01: Use the products, use them regularly.
• 23:50
  SPEAKER_01: People will comment on the vibrancy and the health of your skin, and you may not even see it yet.
• 23:55
  SPEAKER_01: And so to me, that was just such a turning point that if we can produce beautiful scientific-based products where people can see a visible difference in their skin, sometimes unbeknownst to them, they're taking good care of their skin.
• 24:10
  SPEAKER_01: You know, that was very compelling when when um I started.
• 24:13
  SPEAKER_01: So I kind of wanted to put that introduction.
• 24:15
  SPEAKER_01: I love that.
• 24:15
  SPEAKER_02: No, I love that.
• 24:16
  SPEAKER_02: I think that's really cool.
• 24:17
  SPEAKER_02: And I know that um, you know, one more question I do have to follow with that.
• 24:21
  SPEAKER_02: I know that Swiss-based skincare is always like, I always associate it with like the best of the best.
• 24:27
  SPEAKER_02: Like I just have like very deep admiration for Swiss products.
• 24:31
  SPEAKER_02: And I would love to get um your insight, Jennifer, on this, because I feel like, you know, what is going on that we don't do here in America or anywhere else?
• 24:40
  SPEAKER_02: Because I mean the technology seems to just be much more advanced, you know, out in the products that come out of you know, that part of the world.
• 24:47
  SPEAKER_02: So anything you can share with us?
• 24:49
  SPEAKER_01: Well, I I know uh Jeremy can share some of the the deep science and technology behind it, but there is there is a true source of pride and integrity on safety being always tantamount to anything that's being produced in Switzerland, but very specifically by Cell Cosmet.
• 25:09
  SPEAKER_01: Um, but the precision um in all of the development and the technology in every step of the way of the of the development process, everything is checked, triple checked, everything from triple filtration systems for our water that's going into our products to air evacuations, uh, to having ISO certifications.
• 25:31
  SPEAKER_01: We have four ISO certifications.
• 25:33
  SPEAKER_01: Jeremy loves this topic.
• 25:35
  SPEAKER_01: Um, but for me, it's it's about every point in the process, we are making sure that we are at the highest standards to protect the end consumer, bottom line.
• 25:46
  SPEAKER_01: We want to deliver the best quality products and we want to protect them in every process.
• 25:50
  SPEAKER_01: Doesn't mean that every person's skin isn't different, but we've taken all the safeguards to deliver the highest quality products.
• 25:57
  SPEAKER_01: And Cell Cosmet is 100% Swiss made.
• 26:01
  SPEAKER_01: So when we look at from our footprint and the impact we make, um we make sure that 100% Swiss made, um, and that every every uh step in the process complies with all the EU standards, which are very important.
• 26:18
  SPEAKER_00: Yeah, I I think what the difference is we are really, really demanding.
• 26:24
  SPEAKER_00: During each each step, we we would like to make sure we we make the best quality, the best safety.
• 26:31
  SPEAKER_00: An example, once again, it's a link with microbiome.
• 26:34
  SPEAKER_00: We would like to protect to preserve all microbiome, but you know, when you are putting cosmetic product on the market in European authority, you have to prove that you have very low level in terms of contamination.
• 26:46
  SPEAKER_00: And for every normal cosmetic product, you can reach 1000 colony forming unique CFU.
• 26:55
  SPEAKER_00: CFU is a measurement, you need to measure the level of bacteria there is inside of our product.
• 27:04
  SPEAKER_00: Once again, the authority guidelines allow to reach 1000 CFU.
• 27:10
  SPEAKER_00: In your situation or threshold, uh, if you visit our manufacturing um uh lab, every people have a mask to protect the the we have the best protection level to produce the the product.
• 27:29
  SPEAKER_00: And at the end, to make sure that the product um works, you know, the the efficacy, we perform one clinical test for each product, not only euro product.
• 27:40
  SPEAKER_00: For example, with gentle clean cleanser, just a cleanser, we perform clinical tests to make sure that you preserve the hydrolipid films that we hydrate, there is gentle, there is no aggressive, and finally for each product we make the best uh quality, make best standard uh as possible.
• 28:00
  SPEAKER_02: Wow, that yeah, 10 10 is very, very low.
• 28:03
  SPEAKER_02: Yeah, I was gonna say that's basically sterile.
• 28:05
  SPEAKER_02: So yeah, no, but for sure.
• 28:07
  SPEAKER_00: No, but 10 10 CFU is equivalent to the pharmaceutical standard.
• 28:12
  SPEAKER_02: Yeah, that's amazing.
• 28:14
  SPEAKER_02: I mean, I've gotten some products.
• 28:15
  SPEAKER_02: I mean, no, I'm not you know talking bad about any other brand, but like sometimes I've gotten PR where I'm looking at the bottom.
• 28:21
  SPEAKER_02: I'm like, I think something is growing in this.
• 28:24
  SPEAKER_02: This is not good, you know.
• 28:26
  SPEAKER_02: So definitely not good.
• 28:28
  SPEAKER_02: Yeah.
• 28:29
  SPEAKER_02: So there's a huge difference, actually.
• 28:31
  SPEAKER_02: I mean, it just keeping that in mind between like some of the products I've seen, you know, is that don't go through that regulatory, you know, rigorous check at every level.
• 28:40
  SPEAKER_02: That's that's a huge, huge thing.
• 28:42
  SPEAKER_02: I think for anyone consumers out there, I think that should be for us at this point.
• 28:47
  SPEAKER_02: Now that we've seen that there is clinical grade, actual clinical grade skincare, there should be an absolute understanding in the consumer base that like we demand that.
• 28:56
  SPEAKER_02: You know what I mean?
• 28:57
  SPEAKER_02: It's it's there shouldn't be a compromise with that because especially if you're buying something that's supposed to really help you with things like acne or anything, you know, that's like a pathology, you have to be very careful that there have been regulatory things that have been, you know, uh implemented in the production of those you know products that you're using.
• 29:15
  SPEAKER_02: So I encourage that for all of our listeners.
• 29:18
  SPEAKER_02: But Dr.
• 29:18
  SPEAKER_02: Schlayer, I want to talk to you about postbiotics.
• 29:20
  SPEAKER_02: I would love for you to talk about this topic as a general understanding so our listeners can understand like what are postbiotics and also how are you guys approaching them differently?
• 29:31
  SPEAKER_00: That's a good question.
• 29:32
  SPEAKER_00: You know, postbiotic defined as a preparation of inanimate microorganisms andor their components or byproduct of good bacteria having a benefit, good effects on the health of the host.
• 29:47
  SPEAKER_00: It was published by Nature in 2021.
• 29:52
  SPEAKER_00: Um finally, because in cosmetic products it's forbidden to put living bacteria.
• 29:58
  SPEAKER_00: So we decided to capitalize on the good byproduct, some metabolites named postbiotics.
• 30:06
  SPEAKER_00: And finally, we create our own blend of three postbiotic coming from uh marine bacteria uh living in really stressful situations, you know, uh because these bacteria, the postbiotic coming from these bacteria are living in really stressful situations.
• 30:23
  SPEAKER_00: That means they are able to stay alive in stressful condition and capable to product some specific postbiotics.
• 30:33
  SPEAKER_00: And finally, this unique complex is made of one coming from uh it's a secret, you know, the origin, but one is rich in protein and exopolysacchloride to improve the skin barrier, you know, to create a thin former technology.
• 30:49
  SPEAKER_00: Another one comes from bacillus family, is is rich in lipids, antioxidant and anti-inflammatory property, uh, and it protects again blue light.
• 31:00
  SPEAKER_00: And finally, another postbiotic coming from another uh bacillus uh batch is rich in phospholipids, protein and and and vitamins to energize the skin, you know.
• 31:12
  SPEAKER_00: And you are right, we were probably one of the first brands uh capitalizing or introducing postbiotic technology in in the cosmetic product.
• 31:24
  SPEAKER_02: Well, yeah, no, that's very fascinating to me, especially with like extremophiles, like what they produce, you know, um, in terms of yeah, that's that's really cool.
• 31:33
  SPEAKER_02: I think postbiotics have been very misunderstood for a long time.
• 31:36
  SPEAKER_02: I think many times consumers don't really understand where they fit in, you know.
• 31:40
  SPEAKER_00: Yeah.
• 31:41
  SPEAKER_00: So that's true.
• 31:43
  SPEAKER_00: Between probiotic, mean living, prebiotic, a food for for bacteria, and postbiotics, the the byproduct, the metabolites, metabolite coming from bacteria.
• 31:54
  SPEAKER_00: Yeah, you are right, it's quite difficult.
• 31:56
  SPEAKER_00: That's mean we we need to explain a bit here.
• 32:00
  SPEAKER_02: So, you know, I would love to understand, you know, in terms of like trying to kind of stay ahead of the curve.
• 32:06
  SPEAKER_02: I mean, what are you what do you think is the biggest hurdle right now with with this category of cosmetics?
• 32:14
  SPEAKER_02: I mean, I know that my the microbiome is a very complex topic, you know.
• 32:17
  SPEAKER_02: So maybe maybe you can uh kind of tell us a little bit about what what do you think some of the hurdles right now for the industry are in terms of bringing products?
• 32:26
  SPEAKER_02: Obviously, Cell Cosmet is wonderful.
• 32:28
  SPEAKER_02: The brand is, you know, it's it's a great brand, but I'm sure that when you look forward into the future, what do you imagine is gonna happen with the microbiome as it pertains to OTC products?
• 32:40
  SPEAKER_02: And what should where should we be going with this from the science?
• 32:44
  SPEAKER_00: We can imagine, as the first essay in in for the gut, a graft of LC microbiome.
• 32:52
  SPEAKER_00: You know, we can imagine in the future to have a kind of mask made of living, good living bacteria, but a blend capable to mimic the uh the complex microbiota of people with really nice skincare or LC people and so on.
• 33:12
  SPEAKER_00: And I'm sure in the next few years we'll see application with kind of maybe ocatulated living bacteria or masks with biomaterial because in the past I I worked a bit on biomaterial and bioprinting, and I'm sure, and I know uh some companies are working on to develop biomaterial capable to apply and to mimic and modify skin microbiome.
• 33:44
  SPEAKER_00: Today, in Europe, it's forbidden to claim that we modify, we improve, modulate skin microbiota.
• 33:51
  SPEAKER_00: That's why we only claim that we protect, but in reality, we are already able to modify to strengthen skin bacteria.
• 34:00
  SPEAKER_00: In our clinical study, we we we we we observed that 28 days after application of ultravital, one of our iconic products, we improved the the percentage, the quantity of nice bacteria, uh cut bacterium bacteria, which is now to decrease with aging.
• 34:19
  SPEAKER_00: We we are able with our product to maintain and uh increase a bit this this well-known good bacteria.
• 34:26
  SPEAKER_00: Um from one part in terms of technology, once again, coming soon, and some brands are proposing something now, but I'm I'm but I'm not sure it's we will reach the best way, it's to to to um to measure, to identify the unique uh skin microbiota signature for everyone, you know, because today you need PCR, mass spectrometry to perform to sequence the the the signature in laboratory.
• 34:59
  SPEAKER_00: But the next few years I'm sure we'll be able to to in real time on in maybe in in clinics to sequence uh in real time the the signature to be able to predict uh maybe appearance of of some skin disorder.
• 35:18
  SPEAKER_02: That's very, very fascinating.
• 35:19
  SPEAKER_02: I I think you know you're right.
• 35:21
  SPEAKER_02: I think imaging is like the next level also, you know, right now they have all of those imaging techniques and like um you know, dermatology offices, at least I see them a lot here in the States, where they're able to then look at your, you know, your dermis and and figure out like you know different levels of like collagen and you know just elasticity.
• 35:40
  SPEAKER_02: But then when I think about the microbiome, I'm like, you know, there should be some imaging mechanism where we can tell what kind of strains are present on someone's face, you know, if they come into like an office and then you customize it, right?
• 35:53
  SPEAKER_02: Right there based on that.
• 35:55
  SPEAKER_01: Yeah, I think the personalization is going, you know, I think we've all been talking about personalization for a really long time.
• 36:02
  SPEAKER_01: And I just think it's it's getting closer to um more reality of how we can actually turn personalization around in quicker turns, in terms whether it's in a dermatologist's office where you could do these types of scanning.
• 36:16
  SPEAKER_01: And imagine if you could do those kinds of bacteria scannings, you probably could help some of the skin concerns that are just constantly uh kind of, you know, test and try different products to see if you can get the results that you're looking for.
• 36:29
  SPEAKER_01: But if you could get the information right and be able to work those course of action would be huge.
• 36:35
  SPEAKER_01: Um, and I think personalization is really kind of on the next frontier.
• 36:40
  SPEAKER_01: If we can make it efficient to be able to turn it around and and provide the consumer or the client or the patient what they're really looking for and what they want.
• 36:49
  SPEAKER_02: No, I agree.
• 36:50
  SPEAKER_02: And I think you know what's really fascinating about this and everything, um everything that we've discussed is the idea of the pathologies.
• 36:58
  SPEAKER_02: I think I get most excited about people because right now there's a there's a very strong increase.
• 37:04
  SPEAKER_02: And you know, I was reading something the other day about this with people who are being diagnosed with like autoimmune disorders.
• 37:11
  SPEAKER_02: And what that's doing is it's causing an uptick in people with eczema and these like, you know what I mean, these kind of um skin pathologies.
• 37:18
  SPEAKER_02: And when you look at eczema and you look at the dysbiosis of eczema, it's very much linked to, you know, the microbiome.
• 37:27
  SPEAKER_02: It's very much linked to like why the skin barrier is not strong.
• 37:31
  SPEAKER_02: And, you know, I know there's a genetic component there as well, and that's fine, but the microbiome is fascinating to me, especially for very severe conditions, you know.
• 37:40
  SPEAKER_02: I I I think that's where it's going to make a huge difference when it difference when it comes to like how um we are treating allopathically, you know, patients that come in for these serious conditions and you know what those options will look like 10 years from now compared to just right now, where we don't have much, you know, that we can offer these patients.
• 38:00
  SPEAKER_02: So it's very exciting.
• 38:02
  SPEAKER_01: Yeah, it is.
• 38:02
  SPEAKER_01: I think I think the future holds a lot for us in terms of how we care um, how you how doctors care for people and how we care for ourselves.
• 38:11
  SPEAKER_02: Absolutely.
• 38:12
  SPEAKER_02: Absolutely.
• 38:13
  SPEAKER_02: So I I want to actually ask, you know, um, in terms of like being a luxury brand, right?
• 38:18
  SPEAKER_02: Because I mean, I look at Sol Cosmet and you guys are definitely in that luxury sector.
• 38:22
  SPEAKER_02: I mean, how has that been in terms of um fitting because you're so science-backed?
• 38:27
  SPEAKER_02: So, like, where is that uh in between between luxury and like clinical grade?
• 38:31
  SPEAKER_02: I mean, is there like a differentiation, do you think?
• 38:34
  SPEAKER_02: Uh, or is it blending together now?
• 38:37
  SPEAKER_01: I think I think it's blending more and more together.
• 38:40
  SPEAKER_01: Um, I think, I think clinical and luxury were very separate, but I think indiv people are so much more well educated about um ingredients, about how they take care of their skin, of their health, their hair, everything, that I think that there is this blending and people want the science to support luxury too, right?
• 39:02
  SPEAKER_01: You know, it would be like if you were to purchase a very expensive handbag, knowing that the master craftsmen have been at for decades studied, trained to develop something very specific that's going to last and work very well for a very long time.
• 39:19
  SPEAKER_01: It's the same thing in luxury.
• 39:20
  SPEAKER_01: We're looking for the science to support that this luxury, you know, at a price point that is higher than the average to deliver the results that we really want.
• 39:31
  SPEAKER_01: So I think that there's really a blending.
• 39:33
  SPEAKER_01: And I think there's a blending between luxury and clinical from a retail standpoint.
• 39:38
  SPEAKER_01: I think there's a blending of luxury and clinical from a dermatologist, you know, from the dermatologist's office or the plastics surgeon's office, right?
• 39:46
  SPEAKER_01: We're seeing a rise in that space where more and more people are having um plastic surgery and more and more people still continue to go to the dermatologist and seek the advice.
• 39:56
  SPEAKER_01: So I do think that there's a nice blending and merging of the two.
• 40:00
  SPEAKER_01: And I think it's very important.
• 40:02
  SPEAKER_01: Um, if you're going to invest in the health of your skin, you want to make sure that it's backed by science.
• 40:08
  SPEAKER_02: I agree.
• 40:09
  SPEAKER_02: I totally agree.
• 40:10
  SPEAKER_02: Now I want to um, Dr.
• 40:11
  SPEAKER_02: Claire, I want to ask you about the ultra-cell-intensive XT.
• 40:14
  SPEAKER_02: I know that it's a new launch in the US coming up.
• 40:18
  SPEAKER_02: I'd love for you to talk about that and what that is and what we can look forward to.
• 40:22
  SPEAKER_00: Absolutely.
• 40:23
  SPEAKER_00: So, in fact, for the first time ever, we we developed a product with never reached uh of uh cellular um extra concentration.
• 40:35
  SPEAKER_00: You know, uh we already have Ultracell, it's a cure for 12 days.
• 40:41
  SPEAKER_00: Uh, with because I don't speak about the cellular index, you know, it's it's a huge part of personalization of brain.
• 40:50
  SPEAKER_00: You know, we have our technology cytope, uh, blend and cocktail of protein and peptide, and at different concentrations according to the product, and cellular index start by one and and reach level six.
• 41:05
  SPEAKER_00: Six is the highest concentration of Cytope cellular extract.
• 41:10
  SPEAKER_00: And with ultracell XT, we launch the product with 50% more of cellular extract and with index eight.
• 41:20
  SPEAKER_00: What's the benefit?
• 41:22
  SPEAKER_00: That means it's simply we are just doubling the efficacy compared to our classic ultra-cell formula.
• 41:28
  SPEAKER_00: That means, and it's uh for 24 days of treatment after the application, we're doubling the the benefits, the clinical measurement compared to the classical one.
• 41:42
  SPEAKER_00: Uh, and finally, for the first time, we put really highest huge concentration of uh cellular extract.
• 41:51
  SPEAKER_00: And what we observe at this concentration in the lab, we performed some some tests, molecular and cellular test.
• 41:57
  SPEAKER_00: We observed that at this concentration we stimulate the wind-nealing process.
• 42:02
  SPEAKER_00: You know, it's it's there is a test meaning scratch test where we are able to mimic a skin injury and we we measured the capacity.
• 42:12
  SPEAKER_00: Uh and if we are able to accelerate the recovery step and the wound-healing test.
• 42:18
  SPEAKER_00: And at this concentration with the IC8 cellular index, we accelerate the the the this step.
• 42:26
  SPEAKER_00: So that means this product is already used for post-procedure because it sues the skin, it reinforces uh skin barrier function, it decreases the redness, and with this concentration, we will improve significantly the recovery, especially the the wound healing process, and so it makes sense for post-procedure application, for example.
• 42:49
  SPEAKER_02: Oh wow, that's really exciting for post-procedure.
• 42:52
  SPEAKER_02: That's really, really um fascinating.
• 42:54
  SPEAKER_02: So I'd never thought about that with the microbiome, how it can help with post-procedure stuff, because that makes sense actually in the wound healing.
• 43:03
  SPEAKER_00: Um that's it it's not the the the microbiome, it's this activity is burned by cytopep, you know, the blend of protein peptide.
• 43:12
  SPEAKER_00: It's it's not due to uh postbiotics.
• 43:15
  SPEAKER_00: Yeah.
• 43:15
  SPEAKER_01: But there is post there is postbiotics in the product, so there are only two.
• 43:21
  SPEAKER_01: So it's it's cytope plus the postbiotic.
• 43:24
  SPEAKER_01: Um, but the all of the testing that we've been doing is specifically on cytopep and how um, as we've been talking with dermatologists, the opportunity with pre- and post-treatments with ultracell-intensive truly does make a difference in that kind of recovery period and repair period.
• 43:42
  SPEAKER_01: Um and the the current product today is is brilliant and it is really is a product that consumers is one of our best-selling products and is used regularly to reboot your skin, right?
• 43:55
  SPEAKER_01: Because if this cytope actually, you know, through ATP testing, stimulates the cellular energy, right?
• 44:01
  SPEAKER_01: It boosts the cellular energy in our skin.
• 44:03
  SPEAKER_01: And so that testing proves that we're we're getting our skin to work harder, right?
• 44:08
  SPEAKER_01: When we apply uh cytope to the skin.
• 44:11
  SPEAKER_02: That makes sense.
• 44:12
  SPEAKER_02: Yeah, that makes sense.
• 44:13
  SPEAKER_02: Well, it's very exciting, you know.
• 44:14
  SPEAKER_02: I think that w the way you guys are really approaching this topic is so novel and it's exciting to see that technology is is now, you know, really advancing um when it comes to this.
• 44:25
  SPEAKER_02: It used to be something micro the microbiome, peptides, all of these were such buzzwords for me, you know, even a year ago.
• 44:32
  SPEAKER_02: And I I always used to look at brands and say, I just wish that we had more understanding, you know, of of what the how this works.
• 44:39
  SPEAKER_02: Is it even working?
• 44:40
  SPEAKER_02: And I feel like you guys are really kind of bringing that forward for consumers to get behind this the science and really understand how these things work and physiologically how they actually improve skin health overall more than anything.
• 44:53
  SPEAKER_02: So very exciting.
• 44:55
  SPEAKER_02: Thank you.
• 44:56
  SPEAKER_02: Well, thank you both so much for your time.
• 44:58
  SPEAKER_02: This has been so great to learn from you and to chat with you.
• 45:00
  SPEAKER_02: I hope everyone listening, I hope you guys learned as much as I did.
• 45:03
  SPEAKER_02: Um, but you know, I'm a huge believer in the line.
• 45:06
  SPEAKER_02: I think it's wonderful.
• 45:07
  SPEAKER_02: I've been using it and I love it.
• 45:08
  SPEAKER_02: Um, it's it definitely does make a difference.
• 45:11
  SPEAKER_02: After you use it for even a week, I think you will start noticing changes in your skin.
• 45:15
  SPEAKER_02: It just look you look healthier overall.
• 45:18
  SPEAKER_02: So yeah, it's very nice.
• 45:20
  SPEAKER_01: Well, thank you so much for having us.
• 45:21
  SPEAKER_01: Yeah, yeah.
• 45:22
  SPEAKER_02: Happy throws that.
• 45:25
  SPEAKER_02: Thank you so much.
• 45:27
  SPEAKER_02: Hey guys, so I hope you love that episode.
• 45:29
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