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The Sic That Screamed: Half a Milligram, Full Psychedelic Mystery
The Sic That Screamed: Half a Milligram, Full Psychedelic Mystery
Half a milligram of quipazine is printed in the scientific record with a sic-an editor’s signal that the number looks wrong but was left as written-and that same tiny dose is reported to have produced a full psychedelic response. How could a compound that caused reliable nausea and blocked human testing also show unmistakable psychedelic markers in animals at doses supposedly far below prior thresholds?
In this episode, we trace the paper trail from a 1966 research optimism to animal head-twitch responses in 1977, primate…
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