497-hPSC-Derived Immune Cells for Cancer Immunotherapy

Paper Talk · Feb 12, 2026 · 18m

Human pluripotent stem cells (hPSCs) provide a scalable, genetic platform for cancer immunotherapy. By engineering iPSCs to create "off-the-shelf" CAR-NK, CAR-T, and CAR-macrophage cells, researchers can enhance anti-tumor activity while reducing immune rejection and toxicity.

References:

Human pluripotent stem cell-derived innate and adaptive immune cells for cancer immunotherapyShah, Zahir et al.Cell Stem Cell, Volume 0, Issue 0

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