Latest / The Sirona Health Podcast: PMDD, Hormones & Mental Health
Why Do Some Women Get PMDD and Others Don't? The Genetics Behind It
If two women have identical hormone levels but completely different experiences of their cycle, what's actually different between them? In this episode, Dr Georgina Standen goes back a step further than hormones themselves, into the genetics and cell biology behind why some brains are wired to be more hormone-sensitive than others.
In this episode:
The classic hormone-suppression study that proved PMDD isn't about hormone levels at all
What twin studies tell us about how much of PMDD is inherited
The specific genes researchers keep finding — ESR1, a serotonin receptor gene, and GABRB2
The…
The skinny
The skinny isn't ready yet — notes appear once the transcript is processed.