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Microglia Overdrive Causes Sleep Loss in Alzheimer's | Lexington News
Scientists at the University of Kentucky have uncovered a shocking twist in Alzheimer’s research: brain immune cells called microglia, not neurons, are the real villains behind sleep loss in the disease. These cells, meant to protect the brain, go into overdrive when they detect amyloid plaques, triggering a damaging cascade that disrupts sleep years before memory issues appear. Think of them like a sprinkler system gone rogue—floods the house instead of putting out the fire. The breakthrough? Researchers found a way to dial down this overactive response, potentially restoring two hours of…
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