Latest / The Operator's Manual with Fexingo: Daily Decisions, Tactical Wins, and Business Execution
How a Single Plant Delay Shook the Global Pharma Supply Chain
In Episode 39 of The Operator's Manual, Lucas and Luna drill into a specific 2025 event: a six-week shutdown at a Pfizer plant in Kalamazoo that created ripple effects across the entire generic drug market. They trace how one manufacturing line went from running at 95 percent yield to zero, why the backup supplier couldn't fill the gap, and what the episode reveals about fragility in pharma operations. Lucas walks through the numbers — 15 percent of the US supply for a common chemotherapy drug vanished overnight — and Luna pushes back on whether regulators should mandate buffer…
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