New Drug Targets Tau in Alzheimer's | Lexington News

Lexington News Today | 2 Min News | The Daily News Now! · Jul 14, 2026 · 2m

A breakthrough in Alzheimer’s research is unfolding with diranersen, an experimental drug that targets tau protein—instead of amyloid—offering a fresh path to slow early disease progression. Delivered directly to the brain via spinal fluid, this antisense oligonucleotide reduces tau production, bypassing past treatment hurdles. While initial trials showed promise, especially at lower doses, higher doses didn’t deliver expected benefits—yet the results are sparking renewed hope. Scientists are also exploring a tau vaccine, heart meds repurposed for brain health, and cholesterol-lowering drugs…