Latest / Skin Anarchy / Reprogramming Skin Cells for True Anti Aging with Serucell

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Reprogramming Skin Cells for True Anti Aging with Serucell · Skin Anarchy

• 0:00
  SPEAKER_00: Hey guys, welcome back to another episode of Skin Anarchy.
• 0:02
  SPEAKER_00: This is your host, Ecta, and I'm really excited to introduce you guys to a new brand that I've come across lately, and mostly because, as everybody knows, we love science-backed options here at SA.
• 0:12
  SPEAKER_00: And I think uh rightfully so because the skincare industry is growing so rapidly and there are so many options, and I think with all the promises out there, it's really important now more than ever to lean on science and to follow it, you know, when it comes to true innovations and skin health.
• 0:27
  SPEAKER_00: So, with all that said, I would love to introduce you guys to the co-founders of the brand Cerucell.
• 0:33
  SPEAKER_00: I have with me today Dr.
• 0:34
  SPEAKER_00: Walter Neto and Dr.
• 0:36
  SPEAKER_00: Brett Gerald.
• 0:37
  SPEAKER_00: Welcome, Dr.
• 0:37
  SPEAKER_00: Neto and Dr.
• 0:38
  SPEAKER_00: Gerald.
• 0:38
  SPEAKER_00: I'm so excited to host you.
• 0:40
  SPEAKER_01: It's a pleasure, it's a pleasure to be here.
• 0:42
  SPEAKER_01: Thank you so much for the opportunity.
• 0:44
  SPEAKER_01: Yeah, thank you.
• 0:45
  SPEAKER_00: Yeah, no, it's it's an honor to host you both and to learn from you today.
• 0:48
  SPEAKER_00: I'd love to understand more about how you guys came to the decision to begin Seri Cell and where all of this, the innovation and the vision started.
• 0:57
  SPEAKER_00: If you could kind of walk us down memory lane.
• 1:00
  SPEAKER_01: Uh yeah, sure.
• 1:01
  SPEAKER_01: So I'll let you know a little bit of my background.
• 1:03
  SPEAKER_01: So uh I'm a licensed physician.
• 1:05
  SPEAKER_01: My uh background is in general surgery, also specializing wounds.
• 1:09
  SPEAKER_01: I started doing research about 30 years ago.
• 1:13
  SPEAKER_01: Started doing uh medicinal plants uh research into the rain into the Brazilian rainforest where I am originally from.
• 1:20
  SPEAKER_01: And then I then from that you know went to doing cancer stem cell research, bone engineering, and skin engineering as well.
• 1:28
  SPEAKER_01: But over the last few years, about eight, nine years, I've been working on CCT, which is cell communication technology, which is the programming of the body, which is how you know what like how your cells communicate and what happens as you get older.
• 1:45
  SPEAKER_01: And then uh and then CERCL was basically born out of this work that I have been done over the last few years, focus on CCT.
• 1:53
  SPEAKER_02: That's really exciting.
• 1:54
  SPEAKER_02: This is Brett, ER physician, um, still practicing and the biomedical researcher as well.
• 2:00
  SPEAKER_02: My mom was a biology professor.
• 2:02
  SPEAKER_02: I have a graduate degree in biology, and uh, I did a lot of work in the lab.
• 2:07
  SPEAKER_02: I've been friends essentially since college.
• 2:09
  SPEAKER_02: We find uh something that interests us, or if there's a question uh that we find fascinating, we we tend to go down these wormholes, and and that was kind of night as for uh seracel.
• 2:21
  SPEAKER_02: Um Walter was doing some really cool stuff uh trying to understand how uh wounds were operating, how how they actually function in real time.
• 2:31
  SPEAKER_02: And so we had a lot of conversations just discussing how how cells interact with each other, and that's that was uh so we pursued this, and that's that's how we are uh evolved to this today.
• 2:44
  SPEAKER_00: Yeah, that's very exciting, actually, because I think this cell to cell communication aspect, I've never really seen it addressed, you know, in the OTC space, and we don't get the chance as consumers to learn as much as I think you would, you know, in medical school and graduate training.
• 2:59
  SPEAKER_00: But I would love if you guys could kind of give us a 101, you know, on this is this aspect of truly like what is what are the hallmarks of wound healing and what are what were some of the things that were kept in mind when you were crafting the brand and coming up with the formulations.
• 3:14
  SPEAKER_01: You know, one analogy that we love to use that you know I think everyone is kind of familiar with is comparing the body to a computer, you know, you have the hardware, which is you know your organs, what you can feel and touch, but you have the software as well, which is the programming of your body.
• 3:33
  SPEAKER_01: Now, as we get older, this programming just started accumulating errors, just like you know, you have a computer, and then you know everything works well, and then 10 years later the computer doesn't run as well anymore, and then you download a new Windows version, then suddenly everything works well again.
• 3:54
  SPEAKER_01: It's basically the same principle.
• 3:56
  SPEAKER_01: Your programming, you know, your cellular programming, you know, the way that your cells communicate when you when you're younger, they are vibrant and the cells communicate in a very robust and a very healthy way.
• 4:10
  SPEAKER_01: And as you get older, this programming start accumulating errors, and things don't work the same way.
• 4:16
  SPEAKER_01: And it is the same way with aging.
• 4:18
  SPEAKER_01: And what we wanted to do, update your cellular programming, and then your aging cells, in a way, they start to remember the way that they used to behave the way when they were younger.
• 4:31
  SPEAKER_01: And that's when you see an increase in elastic and increasing collagen, you see some of the reverse aging signs that we all have.
• 4:39
  SPEAKER_00: Well, you said I'm thinking back to my old computer, you know, from like 2001 and how you would defrag the hard drive or something, you know, because I mean it's a really it's a great analogy.
• 4:49
  SPEAKER_00: And you know, I know right now, you know, longevity science is kind of taking off, and they're talking a lot about like methylation of DNA, and there's a lot of things going on.
• 4:58
  SPEAKER_02: One of the things that's interesting is we don't really can we don't think about aging until we start seeing the ramifications of aging.
• 5:04
  SPEAKER_02: You know, cell cellular aging probably starts in the early to mid-20s uh when you're invulnerable.
• 5:11
  SPEAKER_02: And uh so you don't really notice these effects of these compound issues, you know, be it uh diet, rest, uh UV light, pollution, alcohol, smoking, you know, whatever you throw into the mix, all these things are having direct impact on health.
• 5:27
  SPEAKER_02: And in this case, specifically skin health, and your body, you know, when you're young and vibrant, you don't notice this stuff, and then all of a sudden you're faced with the the ramification, so to speak.
• 5:38
  SPEAKER_00: Yeah, it kind of like builds up over time, you know.
• 5:40
  SPEAKER_00: Absolutely.
• 5:41
  SPEAKER_00: I know in skin health, I'm sure both of you are pretty familiar with it.
• 5:44
  SPEAKER_00: I but for consumers out there, we talk a lot about like micro trauma, and you know, people discuss this a lot in a way that I think is they're using it as an umbrella term, but I want to further understand from a wound healing perspective about this concept of micro traumas.
• 5:59
  SPEAKER_00: You know, I know um you just mentioned UV light, right?
• 6:02
  SPEAKER_00: And I think along with that comes things like you know, physical exfoliation, little nicks and tears that we might get in our skin.
• 6:09
  SPEAKER_00: So, how does wound healing play a role in our day-to-day skin health and just kind of you know repairing these little micro traumas?
• 6:17
  SPEAKER_01: Yeah, I think that like, you know, in order for us to understand aging in particular, I think we need to understand what actually happens on your skin in the pathology level, right?
• 6:27
  SPEAKER_01: When you look at the national slides, because we have actually done biopsies and trying to figure it out.
• 6:32
  SPEAKER_01: And uh, you know, and that kind of you know makes me think of uh an article no animal testing, the biopsies were on us, yes, yeah, yeah.
• 6:40
  SPEAKER_01: They were not on us, that is true.
• 6:43
  SPEAKER_01: Self-testing, yeah.
• 6:44
  SPEAKER_01: But uh, but you know, like uh you know, there was this L'Oreal study that was basically conducted on the 1980s, you know, they're really trying to understand what is the difference between uh somebody who is 18 and somebody who is 60 when it comes to their skin.
• 7:01
  SPEAKER_01: You know, what what is the difference?
• 7:03
  SPEAKER_01: So they actually saw a decrease in elastin, uh, that which makes your you know your screen in that elasticity that we all naturally have when we're younger, you know, a decrease in collagen.
• 7:15
  SPEAKER_01: And we also see change in what we call like the red ridge.
• 7:19
  SPEAKER_01: You know, uh the red ridge is basically the interface between the two layers of the skin that we have.
• 7:27
  SPEAKER_01: So based on the skin, we have two layers.
• 7:30
  SPEAKER_01: We have the dermis, which is the deeper, which is the deeper layer, uh, is made 90% of this particular cell type named fibroblast, and that is the epidermis, which is the top layer where you can feel and touch, and that's made 90% of this other particular cell type named keratinocytes.
• 7:48
  SPEAKER_01: Now, the interesting part about this two layers is that the epidermis has no blood vessels.
• 7:57
  SPEAKER_01: Two skins, so these two layers are communicating basically at all of the time, you know, when it comes to a wound, when it comes to any kind of stress that basically creates them to do.
• 8:08
  SPEAKER_01: Particular interface that you have when you're younger, they they almost look like legolocs, you know.
• 8:17
  SPEAKER_01: They, you know, the two layers connect each other and they are almost in an undulating pattern.
• 8:23
  SPEAKER_01: When you get older, this onulated pattern becomes almost like a flat line.
• 8:28
  SPEAKER_01: But skin, you know, is not con the two layers are not connected, and that's what causes your thin skin, you know, when you get older.
• 8:36
  SPEAKER_01: Interface is decreased so that it's less oxygen, so there is less nutrient, and there is less support going from the dermis to the epidermis, because the epidermis, like we're talking about, is avascular and has no blood vessels.
• 8:51
  SPEAKER_01: So these are the things that we actually need to understand how actually aging skin is, you know, on a on a cellular level.
• 9:01
  SPEAKER_01: What we do with a serous cell, we take all of that into consideration.
• 9:06
  SPEAKER_01: And uh what we try to do, you know, we try to mimic what of what your skin is in a dish.
• 9:13
  SPEAKER_01: That's why the importance is of the dual cell secretome, of the multicellular secretome that we actually create, because your skin is not a particular cell line.
• 9:23
  SPEAKER_01: And that's what also makes us different from having a single cell line secretomes like you've seen you know in some other brands.
• 9:31
  SPEAKER_01: And then we kind of, you know, so we use these healthy cells, we try to replicate what your skin is in a dish, then we create a stress because you only heal when you're wounded, right?
• 9:41
  SPEAKER_01: You know, being a cut, being in a burn, everything that you do, it is a stress.
• 9:46
  SPEAKER_01: So when your body is stressed, it starts this cascade of signaling, basically make your skin healing.
• 9:53
  SPEAKER_01: And then we we we do the same thing, you know, in on an in vitro or in a dish, you know, in our lab, and then we collect all of the signaling that the cells are basically trying that you know to heal themselves, which you would see normally in me or you, you know, if we get cut or if we get burned.
• 10:14
  SPEAKER_01: And that's what basically serial cell is.
• 10:17
  SPEAKER_01: Now, what makes us different is that a lot of uh a lot of brands out there they use like a single cell line.
• 10:25
  SPEAKER_01: I'm not gonna mention any names, you know, of particular brands.
• 10:28
  SPEAKER_01: There's a few brands.
• 10:29
  SPEAKER_01: There are a few, not many, but there are like a few brands out there, but that's only seen part of the picture of the picture because that's not how your skin actually works, you know.
• 10:40
  SPEAKER_01: And we we have actually analyzing if you if you use a single cell line, either fibroblasts or keratinocytes, or if you use the dual cell line, you know, which is keratinocytes and fibroblasts together, the result of the stress that the physiological stress that we created to these cells, it is a way different.
• 11:03
  SPEAKER_01: It's much more complex, which mimics much more of what the human body can actually do.
• 11:09
  SPEAKER_01: So what we do is literally, we just we don't really create anything.
• 11:15
  SPEAKER_01: We just tap on our naturally ability to heal, and that's where serious cra really shines, and that's what it's based on.
• 11:23
  SPEAKER_02: One thing to consider is like when uh when people go to their aesthetician and they're getting poked, prodded, scraped, burned, peeled, that's all an attempt to injure the skin to get to elicit a response.
• 11:38
  SPEAKER_02: Uh, we're able to elicit a similar response in a dish.
• 11:42
  SPEAKER_02: So you don't have to go through all those sort of uh mechanizations.
• 11:46
  SPEAKER_00: I think we've used this analogy a lot on the podcast where you know somebody will come on and we're trying to explain to them how does skin care work.
• 11:54
  SPEAKER_00: And I you had spoken very wonderfully about this, about the keratinocytes, how they're ava it's a vascular layer.
• 12:00
  SPEAKER_00: There's they're really dead cells, you know.
• 12:02
  SPEAKER_00: So whatever you're putting on top of them is really like a broth that you put in a cell culture, you know, you're putting the media on top of the cells and you're feeding them, right?
• 12:11
  SPEAKER_00: That's the whole idea that people are going for.
• 12:13
  SPEAKER_00: But it really is important to highlight exactly what you guys explained, which is that there's this interconnection between the dermis and the epidermis, and the actual signaling that's happening is what's leading to healthy outer layer skin that we're looking at continuously.
• 12:27
  SPEAKER_02: You bring up a really important part, you know, like when we do our secretome, there's there's well over uh a thousand proteins and and molecules that we are able to generate, and they all act in concert to maintain a homeostasis.
• 12:42
  SPEAKER_02: And that that's you know, at the fundamentally, that's what the body is trying to do is just maintain uh a certain uh level of of cellular activity.
• 12:52
  SPEAKER_02: These to elicit an injury is to kind of uh ramp up that that response, otherwise the cell is going to be operating kind of at as as it always does.
• 13:03
  SPEAKER_02: And so it, you know, this is the the other thing that's great, I think, that is unique to our product is that we utilize since we're utilizing skin cells, it's already a language that the body is aware of.
• 13:17
  SPEAKER_02: You know, we're as Walter alluded to, we're not adding anything new, we're just augmenting what's already there.
• 13:23
  SPEAKER_00: Yeah, no, that makes a lot of sense.
• 13:24
  SPEAKER_00: And I and I would love to actually learn more about the KFS uh complex.
• 13:29
  SPEAKER_00: I know that's your proprietary ingredient in your formula, and if you could talk to us a little bit about this.
• 13:34
  SPEAKER_01: Yeah, so you know, uh everything has you know comes comes from the anatomy of your skin.
• 13:39
  SPEAKER_01: So we take into consideration how the skin actually works, especially with the epidermis being avascular, and these two cells interacting all of the time for anything that they do.
• 13:50
  SPEAKER_01: So it made sense for us, you know, whenever we were collecting the signalings, you know, that we get from these cells under uh stress, if we could replicate the skin much closer to what your natural skin actually is, and that means like these two cell lines working together.
• 14:07
  SPEAKER_01: So, and that's what we do.
• 14:08
  SPEAKER_01: So we create this multicellus secretone that resembles much more of your skin, what actually is and what it looks like than if you're using a single cell line, and that's what KFS was actually born.
• 14:21
  SPEAKER_01: And just going back, you know, when when uh talking about aging, you know, I mean, I like to call true anti-aging, you know.
• 14:30
  SPEAKER_01: Uh it's not something that is just superficial, you know.
• 14:35
  SPEAKER_01: To really achieve what anti-aging really means, you need to, you know, boost your elastin, you need to boost your collagen, you know, it's something that really is, you know, is on the cellular level.
• 14:49
  SPEAKER_01: And that actually comes back to us on the ret ridge, you know, because some of the biopsies that we have actually seen is that some of the things that we see on the ret ridge when the ret ridge gets older, which is the flattening of the line, we have seen some some of some reverse on that to basically you know make the ret ridge much more like similar and look like when you are younger.
• 15:17
  SPEAKER_01: So that's what I we we like to call like true anti-aging.
• 15:21
  SPEAKER_01: And we think that we can achieve that by mimicking what your skin is with a dual cell line on a cellular level with the stress, which you know creates a much more you know innate intelligence of healing that we have than if you're using like you know a much more uh simplistic approach with the which would be a single cell line.
• 15:46
  SPEAKER_02: Mass specs of our single cell lines.
• 15:48
  SPEAKER_02: We did uh keratinocytes, we did fibroblasts, and they they all produced you know unique profiles.
• 15:55
  SPEAKER_02: But what was really cool to witness is when we when we co-cultured them together, there was actual synergy and there was molecules and proteins created that didn't exist in either of the of the single uh cell line samples.
• 16:09
  SPEAKER_02: So there is real communication happening.
• 16:12
  SPEAKER_02: Uh you know, it just goes to the the you know the brilliance of the body and how how amazing it is.
• 16:19
  SPEAKER_02: Um, you know, Walt spoke about the the ret ridge.
• 16:23
  SPEAKER_02: You going back on that, we see in our you know, as people continue to use our our product, the the KFS serum, we see increase in the undulation uh of the ret ridge.
• 16:35
  SPEAKER_02: So we're getting more surface area and more ret pegs, so pegs.
• 16:39
  SPEAKER_02: So you have increased communication, you have increased vascularity, increased oxygenation, that's all going to the epidermis.
• 16:47
  SPEAKER_02: Interestingly, also you're seeing below that, you're seeing a much more organized uh cellular matrix of uh of collagen and elastin below the ret ridge.
• 16:59
  SPEAKER_02: So you know the the whole all all these cells are responding to this, to these signaling in a positive manner.
• 17:07
  SPEAKER_00: The ret ridge, you guys, just for I know um we just you mentioned undulating, and that's a great word to use that just for everybody to understand, it's kind of like your skin taking like dips into the dermis.
• 17:18
  SPEAKER_02: So it like goes the dermis.
• 17:20
  SPEAKER_02: I think if you're looking at a profile, it's kind of like a wavy line.
• 17:24
  SPEAKER_02: Yeah, and uh, you know, and as if you think of a wave, uh a wave, there's much more surface area under a wave than there is under a flat line.
• 17:33
  SPEAKER_01: And you know, and and it is basically the interface, you know, is the communication line between the two layers.
• 17:41
  SPEAKER_01: And uh, you know, as we were talking about, you know, because the epidermis is avascular, that's a very important line because everything from the dermis has to have to diffuse through this layer to nourish the epidermis.
• 17:57
  SPEAKER_01: So the red ridge is basically the communication line where everything diffuses from the dermis to the epidermis.
• 18:04
  SPEAKER_00: Your top layer, the epidermis doesn't communicate with the dermis, it doesn't know, like there's no communication in the body telling it what it needs.
• 18:11
  SPEAKER_00: You're gonna see levels like the signaling is gonna be completely different because your body's interpreting that everything's fine on the top layer when it's not.
• 18:19
  SPEAKER_02: And like, you know, for example, uh, people using collagen creams and things like that, you know, collagen's a huge molecule, it doesn't penetrate through the skin, you know, because the skin is a huge barrier.
• 18:30
  SPEAKER_02: So, yes, it acts as a uh moisturizer, a moisturizer and a good shield, but it's not able to diffuse through and and really uh augment change.
• 18:40
  SPEAKER_00: It's what is it, 500 Daltons limit that if you're putting something on your skin, like it will not go through and collagen is way beyond that.
• 18:48
  SPEAKER_00: We really miss the mark, you know, with a lot of the products we see on the market where you know we're just thinking that okay, if I slather something on my skin, you know, it's gonna eventually glow and it's gonna look beautiful and my makeup's gonna look great on it, but really that's not what's going to heal your scars or your hyperprimation, or you know, that's it's not doing anything because again, the same principles that you stated, you know, you're not getting the adequate blood supply and the nutrients that come from the dermis.
• 19:16
  SPEAKER_02: You know, people that utilize our products they feel some changes initially, but you're not really going to start seeing the results for a couple weeks because this, you know, the skin is turning over every 28 to 60 days, depending on your age.
• 19:31
  SPEAKER_02: As you increase this the healthy signaling over time, that's when you start seeing the results of healthier skin.
• 19:40
  SPEAKER_02: And you know, there's no there's no magic bullet for this stuff, uh, contrary to uh what people would tell you.
• 19:47
  SPEAKER_02: So you know, we're we're really very much uh results driven, and uh and so that's where our you know our our science focuses.
• 19:55
  SPEAKER_00: I love that.
• 19:56
  SPEAKER_00: I I love that so much, and I'm so glad you guys are bringing that to the space because we need more of that.
• 20:01
  SPEAKER_00: I think with you know, I'm sure both of you have seen it, you know, in the world of medicine, I think it's kind of a bubble because you're so used to actual like you know, like medications and stronger, stronger options, but in the OTC space, it's so unregulated, and now people are hitting a wall, you know.
• 20:17
  SPEAKER_00: I I see so many posts all the time where consumers are saying, well, nothing works, you know, I'm gonna go apply some beef tallow to my skin.
• 20:24
  SPEAKER_00: Yeah, and I'm like, that's not it.
• 20:26
  SPEAKER_00: That is not it, you know, you have to keep looking.
• 20:29
  SPEAKER_00: So what you're doing is is so novel and it's so needed in this space because there's consumers are very confused.
• 20:35
  SPEAKER_00: I that's what I see every day.
• 20:37
  SPEAKER_01: One thing that I love about our product is what Brett mentioned, like these are all natural peptides, you know.
• 20:44
  SPEAKER_01: So this is a language that your body understands.
• 20:47
  SPEAKER_01: So these are not synthetics like you, like you see in uh in in a lot of products out there.
• 20:54
  SPEAKER_01: So in a way, it's a programming that your body already understands.
• 20:58
  SPEAKER_01: We are just updating and make your body remembering them the way that you used to behave when it was younger.
• 21:05
  SPEAKER_02: One thing that's also kind of uh I think cool about our product is is that it you see uh it positive impacts on ages and and types, skin types, and male and female, because what happens is the body, you know, whatever it needs, it finds in our serum, and then it gets augmented.
• 21:26
  SPEAKER_02: And so what doesn't need it, you know, it's so we get a lot of positive feedback where people have tried numerous products, they just weren't ever getting the result they needed, and all of a sudden they are getting something, they find that they don't need makeup now.
• 21:42
  SPEAKER_02: They you know, like they're almost going down to just just our serum and they're they're thrilled about it, which is it's cool.
• 21:50
  SPEAKER_02: It's I work in an emergency room typically, so most of my my patients are are not terribly happy, so it's really cool to to see people.
• 22:00
  SPEAKER_02: You know, coming back with exciting and and positive uh results.
• 22:05
  SPEAKER_00: At the end of the day, you know, I think what we're all really looking for is for our skin to heal as we age, you know, and I think that a lot of us kind of miss the mark and we we look over that, but really with the skin concerns that I hear about, you know, from just general people that chime in to us, you know, as a show, they they ask us, you know, what what's gonna help with my sagging skin?
• 22:27
  SPEAKER_00: What's gonna help with my hyperpigmentation, like I mentioned before, you know, or like for example, acne is a huge concern.
• 22:33
  SPEAKER_00: And not just the acne, but like the post-inflammatory stuff, you know, like the hyperpigmentation, the scars, the pitting.
• 22:40
  SPEAKER_00: I mean, it's a huge problem.
• 22:42
  SPEAKER_00: And there's nothing on the market that is really doing what we're talking about here, where they're saying we're gonna have to change how your skin communicates, you know, for it to actually heal.
• 22:52
  SPEAKER_02: There's something about aging with dignity, and there's a lot of products that people are initially have you know a fond response to, but then all of a sudden there's you know, they're left with like scar tissue, uh, you know, some some pretty invasive things.
• 23:08
  SPEAKER_02: And and ideally with our products, people are circumventing this and they don't have to experience that, you know.
• 23:15
  SPEAKER_02: If if you're 70, you're never gonna look 20, but you could look 40, you know, and that's not an unreasonable ask if if you're taking care of yourself.
• 23:23
  SPEAKER_00: I want to actually um highlight one thing.
• 23:26
  SPEAKER_00: I think Walter, you said this about the peptides, and I I think this is so important to highlight because all of us know about peptides.
• 23:32
  SPEAKER_00: So, like if you're a skincare enthusiast, you love skincare, you've heard peptides at some point, but that's very important what you said versus natural peptides versus synthetic peptides.
• 23:42
  SPEAKER_00: And this is a concept I've never heard anyone really talk about, where they don't discuss that with your natural peptides, they're actually going to go to the location that they're supposed to go to.
• 23:53
  SPEAKER_00: There's a lot of synthetic peptides, don't possess that.
• 23:56
  SPEAKER_00: I would love to talk to you guys a little bit about this AI-driven approach.
• 24:00
  SPEAKER_00: I know that you've utilized it in your brand, and just I would love to learn more about AI RD.
• 24:06
  SPEAKER_02: Our uh technology it is we have six manufacturing patents.
• 24:11
  SPEAKER_02: And so what that is, is when we we talk about a secretome.
• 24:16
  SPEAKER_02: So a secretome, for those that don't know, is uh the stress response uh of a cell.
• 24:23
  SPEAKER_02: And so what we've we've done and we're exploring, uh not to get too crazy with it, but what we're going is like so these secretomes are the essentially data banks of your body, and uh what we do is like when we're uh investigating a particular thing, we will access our secretome and uh and we we educate an AI about it, and and that means so say we have problem A, and so we try to give as much information to the particular AI about problem A, and problem A, everything that that's normal about it, and then we try to find as many things that are abnormal about it, and then we task the AI to review what we're doing in our what we have in our secret home to f possibly uh create um therapies or possible to address a particular issue.
• 25:22
  SPEAKER_02: Uh so like you know, one of the things we have a biomedical side of our company that we're we're using this to look at other organs, but skin is where kind of where our love is because it's where we deep dove with the most hard science.
• 25:35
  SPEAKER_02: And so this is where we're really pushing, and we we're we're coming up with some really exciting results.
• 25:41
  SPEAKER_01: Multicell cyclone can stand on its own, or it can also be used as a library when you can pick and choose with the help of AI to determine some possible combination to have a therapeutic use.
• 25:56
  SPEAKER_01: We already on the second phase of that particular uh process, and uh we actually have partner with uh Marshall University Pharmacy School to do some testing for us, and we're really excited to the next phase of that of that project.
• 26:13
  SPEAKER_00: I think AI is is definitely you know the next step in everything, pretty much.
• 26:18
  SPEAKER_02: But I think you know, the the thing that's uh what it's it's providing us is you know, we had reams and reams uh to you know of data, and there's just no efficient way of going through it.
• 26:32
  SPEAKER_02: And and AI just provides a tool to to evaluate data, look for patterns that you may be aware of, or more likely not be aware of.
• 26:42
  SPEAKER_02: It's not making decisions, it's it's just accelerating accelerating uh data interpretation so we can you know to see what the next step is.
• 26:52
  SPEAKER_02: It's it's expedited our research by uh decades, probably.
• 26:57
  SPEAKER_00: I think that the more we can learn, the faster we can learn it about skin health, the more likely we're gonna get consumers away from this whole like you know, made in a kitchen skincare and get them to the real options, you know.
• 27:09
  SPEAKER_02: Oh yeah.
• 27:09
  SPEAKER_02: I mean, gosh, yeah, you know, Walter and I you know used to watch like Shark Tank or some shows like that, and you're just like, what is going on?
• 27:18
  SPEAKER_02: And that was kind of like, you know, when we were crazy enough to create a brand, we're like, well, we're gonna make something that's medically sound and something we'll be proud of, you know, to put out on the market.
• 27:29
  SPEAKER_02: And that's how KFS started.
• 27:31
  SPEAKER_01: Yeah, you know, like and and KFS is a total spin-off of my of our burning wound healing research.
• 27:38
  SPEAKER_01: And the way that actually we we decided to develop serious is that like, because you know, since this was created for wounds and but just learning everything that goes around the wounds and learning about cell communication and how it degrades with uh time.
• 27:54
  SPEAKER_01: You know, I was talking to Brett and I was like, Brett, I think that this could have some really positive impact on aging cells, you know, a very small batch, and uh we gave it to some, you know, to some friends and family, you know, about 50 to 100 bottles to see, and people went absolutely crazy about it.
• 28:10
  SPEAKER_01: And that's how Cericell was born.
• 28:12
  SPEAKER_00: I I'll tell you what, you know, I've tried the products, I really love them, they're very nice.
• 28:16
  SPEAKER_00: Like even on first application, I mean the formulations are very, very nice and very sophisticated, and also obviously the long-term facts are really the the bread and butter here, right?
• 28:26
  SPEAKER_02: Well, at the end of the day, people want stuff that that doesn't, you know, they want things that impact their life positively.
• 28:32
  SPEAKER_02: They don't they don't want a homework assignment.
• 28:34
  SPEAKER_02: So it's gotta be results driven and it's gotta play well with others.
• 28:39
  SPEAKER_01: Our product is hypoallergenic, it absorbs very easily.
• 28:43
  SPEAKER_01: We only recommend to be used first, but you can layer all the products with it if you want to.
• 28:49
  SPEAKER_01: Uh, but uh you know, it plays well with uh others, it does great by itself as well, and uh, you know, we we get some really great comments.
• 28:59
  SPEAKER_01: I wanted people to have a good experience, you know, when they are applying our serums.
• 29:04
  SPEAKER_02: Yeah, I mean, like even our bottle, like we designed the the dispenser so you it's actually overfilled and you get 100% of the bottle because you know we were reading when we first started that you know, people buy products and sometimes up to 20 was unaccessible, you know.
• 29:19
  SPEAKER_02: Yeah, and we're like that well, that's that's not cool.
• 29:23
  SPEAKER_02: We try to be really thoughtful in how we created this.
• 29:26
  SPEAKER_02: Nailed it.
• 29:27
  SPEAKER_00: You've really nailed it.
• 29:27
  SPEAKER_00: I mean, it's not thank you.
• 29:29
  SPEAKER_00: Yeah, no, it's it's a great set of products, and I think that it definitely shows that you've put thought into, you know, even the little things, even though the science is hard hitting, but I think when it comes to unfortunately, you know, with consumers, all of the other stuff also, you know, it resonates sometimes more than it should, in my opinion, you know.
• 29:47
  SPEAKER_00: But with with the products, I've noticed everything's great.
• 29:49
  SPEAKER_00: The packaging's great, that you know, the application, like you know, Walter, you were mentioning it absorbs, it absorbs really fast actually into your skin.
• 29:57
  SPEAKER_00: And it doesn't leave any kind of residue and it's very, very workable, you know.
• 30:01
  SPEAKER_00: And I know for a lot of women out there, this is very important for us consumers, you know, female consumers, because we do wear makeup.
• 30:08
  SPEAKER_00: It's important to have make sure your skincare is working with your routine.
• 30:11
  SPEAKER_00: It's not just, you know, that's it's not just the only thing you do, and then you can't do anything afterwards.
• 30:16
  SPEAKER_00: So that is a big aspect of it.
• 30:17
  SPEAKER_01: You know, we had some uh makeup artists who have you know they love our products so much, they all they all they were using almost as a primer before makeup.
• 30:26
  SPEAKER_02: Yeah, we had a we had an Oscars event a few years ago where you had four winners and like Wow, we didn't know who they were, but uh we got some feedback, so that was kind of cool.
• 30:38
  SPEAKER_00: That's really cool, yeah.
• 30:40
  SPEAKER_01: Yeah yeah, yeah.
• 30:41
  SPEAKER_01: We have we have been in the Oscars bag for the maybe three years over the last everybody, everyone wins back, and we have also you know been on the Grammys, uh on all of the Grammy's bags as well over the last three to four years, and the response has been really positive.
• 30:59
  SPEAKER_00: So you're like the secret that all celebrities aren't telling us about, then like we're not hearing about the it's time to let the secret out.
• 31:07
  SPEAKER_00: Yeah, letting it out, no more gatekeeping, you know.
• 31:11
  SPEAKER_02: That's right, no more gatekeeping.
• 31:13
  SPEAKER_00: I really believe in the idea that you know, if you put the science there, it's gonna work.
• 31:18
  SPEAKER_00: And I just I wish more people would understand that, you know, I really do, because at the end of the day, your skin is an organ.
• 31:25
  SPEAKER_00: We've said that, like I think odd nauseum at this point, you know, on this podcast.
• 31:28
  SPEAKER_00: You have to really treat it like that.
• 31:30
  SPEAKER_00: So the fact that you guys have such a heavy-hitting product, it it really brightens my day to know that you're you know you're doing it right.
• 31:36
  SPEAKER_00: But what is the future for series law?
• 31:37
  SPEAKER_00: Anything that's coming up that you can share with us?
• 31:39
  SPEAKER_00: I don't want to pry too much, but anything you can share with us.
• 31:42
  SPEAKER_01: Currently, we have three products on the market.
• 31:45
  SPEAKER_01: We have our eye serum, our facial serum, and our recovery serum, which is our post-procedure, but it can also be used for ultra-sensitivity skin.
• 31:53
  SPEAKER_01: But we have nine products already formulated and ready to be launched.
• 31:59
  SPEAKER_01: Uh, we have uh a next serum, which is we are really excited about that as well.
• 32:04
  SPEAKER_01: We have a dual sphere exfoliant, which we're also very excited, and all this have been tested already.
• 32:11
  SPEAKER_01: We have a hair serum that uh it is people are really loving it right right now, and we have versions of both worlds, you know, because as we were talking about before, our product, you know, KFS takes about two weeks to so you start seeing, you know, a tuning in your lesson in college.
• 32:31
  SPEAKER_01: And but a lot of people want quicker results.
• 32:34
  SPEAKER_01: So we found a way to incorporate our KFS serum with a topical, almost like a topical Botox.
• 32:42
  SPEAKER_01: So you can have the best of both worlds.
• 32:44
  SPEAKER_01: So all of these in the pipeline to be launched in the next few years.
• 32:48
  SPEAKER_02: Yeah, so like people, if they sign up for our email, often we do specials and and we test new products.
• 32:54
  SPEAKER_02: Uh, if you know, if people buy something, we we send other things to see how people like or you know, hopefully not dislike our stuff.
• 33:04
  SPEAKER_02: But we're we're always testing and and trying new things.
• 33:08
  SPEAKER_02: Our approach is let's let's address real world problems with real answers, and that that's kind of what drives the products that we design.
• 33:15
  SPEAKER_00: For everyone listening, if you haven't checked out the brand yet, I will be linking everything in the show notes of this episode.
• 33:21
  SPEAKER_00: So definitely go check them out.
• 33:22
  SPEAKER_00: I got the website, there's a lot of information on there as well, and um some reviews that you can look at.
• 33:27
  SPEAKER_00: But I really recommend that you guys invest in science-backed skincare.
• 33:31
  SPEAKER_00: I cannot stress that enough.
• 33:33
  SPEAKER_00: If you're looking for real options and you want to actually change your skin, you want to heal your skin.
• 33:38
  SPEAKER_00: This is such a solid option for you.
• 33:40
  SPEAKER_00: Check them out.
• 33:40
  SPEAKER_00: But thank you both so much, Walter and Brett.
• 33:42
  SPEAKER_00: This was such an honor to host you and to learn from you.
• 33:44
  SPEAKER_01: Thank you so much.
• 33:45
  SPEAKER_01: Great for the opportunity, you know, because one of the we basically don't do almost like no marketing.
• 33:51
  SPEAKER_01: So, you know, everything that we do is you know has achieved to like an organic, you know, a ground, you know, movement level.
• 33:59
  SPEAKER_01: So being here is uh it was a great opportunity.
• 34:02
  SPEAKER_01: Thank you so much, and we hope that people can try our serum and enjoy it.
• 34:06
  SPEAKER_02: And if people have questions, they can email.
• 34:08
  SPEAKER_02: We'll we're happy to answer.
• 34:09
  SPEAKER_02: Uh Walt and I don't sleep a whole lot, so we're always available.
• 34:13
  SPEAKER_02: Yes.
• 34:13
  SPEAKER_00: Yeah, as true physicians, right?
• 34:15
  SPEAKER_00: Like no sleep, no sleep needed.
• 34:18
  SPEAKER_00: Yeah.
• 34:18
  SPEAKER_00: No, I mean, that's great.
• 34:19
  SPEAKER_00: That's really great.
• 34:20
  SPEAKER_00: I love what you guys are doing.
• 34:21
  SPEAKER_00: And yeah, everybody like chime in to us as well.
• 34:23
  SPEAKER_00: We can connect you to the Serious All team as well.
• 34:26
  SPEAKER_00: So please let us know if you need anything.
• 34:28
  SPEAKER_00: But thank you again, and I'll be back next time.
• 34:30
  SPEAKER_00: Hey guys, so I hope you love that episode.
• 34:33
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• 34:37
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• 34:40
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• 34:55
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• 35:02
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• 35:10
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• 35:12
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• 35:15
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• 35:20
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• 35:26
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• 35:32
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• 35:37
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