343-Sympathetic functional units encoding

Paper Talk · Dec 28, 2025 · 17m

The paper details an article and associated research focusing on the molecular and functional diversity of sympathetic postganglionic neurons within the celiac-superior mesenteric ganglia (CG-SMG) complex. Through single-cell transcriptomics and functional assays like chemogenetics and optogenetics, the study identifies two genetically distinct subpopulations of CG-SMG neurons: Calb2-positive neurons and Nxph4-positive neurons. The research establishes that these distinct genetic identities correlate with specific anatomical projections and physiological roles, with Calb2-positive neurons…