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Early Drinking Rewires Brain for Stress | Science News

New research from UMass Amherst reveals that early-life alcohol use combined with stress can permanently alter brain circuits, leading to reduced cognitive flexibility and increased risk of relapse later in life—even after years of sobriety. The study, using mice with brain structures similar to humans, found that this combo weakens the brain’s natural stress response, particularly in the locus coeruleus, a region linked to decision-making and oxidative damage seen in Alzheimer’s. The findings suggest that quitting drinking isn’t enough to reverse these changes, highlighting the urgent need…

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