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Fentanyl and Medetomidine Mix Threatens Overdose Response | Calgary News

A deadly new drug combo—fentanyl spiked with medetomidine, an animal tranquilizer—is spreading across Canada, causing more intense highs and dangerous withdrawal symptoms, including sky-high blood pressure. Naloxone, the overdose reversal drug, doesn’t fully counteract medetomidine, leaving users vulnerable. As supervised consumption sites close in Calgary, users are returning to unsafe outdoor spaces, while the province pushes a recovery-focused strategy that’s failing to curb deaths—especially in Edmonton, where carfentanil remains a lethal threat. Despite warnings, officials say no deaths…

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