
1257-AI-Driven Nanoplatforms for Targeted Ovarian Cancer
Recent research focuses on overcoming the high mortality and treatment resistance of ovarian cancer by targeting its immunosuppressive tumor microenvironment. Scientists are utilizing single-cell and spatial omics technologies to map the precise location of "exclusion structures" where immune cells like Tregs and TAMs congregate in hypoxic regions to block therapy. These detailed spatial atlases guide the development of biomimetic nanoplatforms, such as cell membrane-coated carriers, which can bypass immune clearance to deliver drugs directly to these core areas. To improve precision, an…
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