Latest / Becker’s Healthcare Podcast / Stacey A. Rizza, MD, Medical Director for Global Commercial Solutions at Mayo Clinic International

Transcript

Stacey A. Rizza, MD, Medical Director for Global Commercial Solutions at Mayo Clinic International · Becker’s Healthcare Podcast

• 0:02
  - There's a small circle of people who truly
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  - Becker's fourteenth annual CEO and CFO roundtable
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  - workforce strategy, and the leadership questions that don't
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  - Chicago.
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  - For the agenda and event details,
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  - visit beckershospitalreview.com
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  - and click on the events tab in the
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  - upper right.
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  - This is Laura Dierda with the Becker's Healthcare
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  - Podcast. I'm thrilled today to be joined by
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  - doctor Stacy Rizza, medical director for Global Commercial
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  - Solutions at Mayo Clinic International.
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  - Doctor Rizza, it's a pleasure to have you
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  - on the podcast today.
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  - Well, thank you so much. I'm really looking
• 1:05
  - forward to our discussion today.
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  - As am I. I think you're doing some
• 1:10
  - fascinating work at Mayo Clinic and really truly
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  - exciting to think about how you've been diving
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  - into many different areas and,
• 1:17
  - some of the funding you've gotten and projects
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  - you're working on. So we'll dig into all
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  - of that. But before we do, can you
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  - tell us a little bit more about yourself
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  - and Mayo Clinic's international practice?
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  - Absolutely. I'll begin with just a little bit
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  - about myself, and then I'd love to tell
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  - you about Mayo Clinic's international
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  - interest and our vision
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  - and our hopes with doing the work we're
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  - doing right now.
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  - So I'm an infectious disease doctor. I'm based
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  - out of the Mayo Clinic
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  - based in Rochester, Minnesota,
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  - and I've been with Mayo Clinic for a
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  - little over twenty years now.
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  - Like many of us in academic medicine, I've
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  - had the privilege of working in not just
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  - clinical medicine,
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  - but also working in education
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  - and in research.
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  - My clinical interests have always been in HIV
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  - and transplant infectious disease as well as tuberculosis
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  - and some of the viral hepatitis work. And
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  - those are the areas where I've had the
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  - opportunity to do some research work, and then
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  - I've been able to work in administration
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  - within Mayo's education shield as well.
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  - So if you've ever seen the Mayo logo,
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  - it has three shields for practice, education, and
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  - research, and I'm
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  - old enough now and been around long enough
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  - for now that I've been able to be
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  - involved in all of that.
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  - And throughout that work, I've also been involved
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  - in some international efforts, which led to me
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  - working with Mayo Clinic International.
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  - So Mayo is a 160
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  - years old, and we have been involved in
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  - international
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  - efforts since the very beginning.
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  - Our founder was originally from England, and even
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  - our founding brothers, his sons,
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  - have been doing international trips
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  - over a hundred years ago because they always
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  - saw the value
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  - of learning from others and sharing the knowledge
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  - that was acquired at Mayo.
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  - So international
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  - work,
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  - global work is just part of Mayo Clinic's
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  - DNA.
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  - So as part of that, Mayo Clinic International
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  - is part of Mayo
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  - that is helping foster and expand Mayo's mission
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  - to be the leaders in global health.
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  - And we see ourselves doing that by working
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  - with groups around the world.
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  - So we don't go and just sort of
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  - stake a claim and build an Mayo Clinic
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  - in other parts of the world because clearly
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  - that would never be effective.
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  - But we
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  - find collaborators
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  - and partners in other parts of the world
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  - that are values aligned and mission aligned
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  - and have
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  - a goal towards serving patients,
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  - advancing health care, and working together to touch
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  - more lives.
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  - And we go into relationships
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  - where we can do that together.
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  - And that's been a privilege. I've been working
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  - with Mayo Clinic International for a number of
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  - years now, and it only gets more exciting.
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  - And the more work we do and the
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  - more
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  - groups we learn from and and work with
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  - around the world and the more patients' lives
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  - we touch, it just becomes more and more
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  - gratifying.
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  - That's amazing to hear. And, you know, what
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  - inspirational work you're doing at Mayo Clinic International
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  - and everything that you have in terms of
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  - the different diseases that you've worked on and,
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  - research development
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  - and community care,
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  - is so critical in order to bring that
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  - treatment to life.
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  - Now, how do you approach bringing Mayo Clinic
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  - standards
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  - of care into such a different healthcare systems
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  - when you're looking across the world? I know
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  - there's a lot of variation in in regulatory
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  - environments too that are different. So what does
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  - that look like as you're trying to bring
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  - Mayo Clinic's ethos into those spaces?
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  - That's a wonderful question. Probably the most important
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  - question.
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  - Whenever you talk to a US based group
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  - that's going to be working in any other
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  - environment in any other part of the world.
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  - And the short answer is you don't bring
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  - Mayo Clinic in its form anywhere else in
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  - the world.
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  - It it wouldn't work and it shouldn't work.
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  - Health care is local.
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  - But what we're doing is we're sharing our
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  - knowledge, we're sharing our experience,
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  - we're sharing the mistakes we made so hopefully
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  - others don't have to make it, And we're
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  - really working collaboratively.
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  - Collaboration is the pivotal word in this.
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  - So as I mentioned briefly earlier, for us
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  - to just cut and paste something from Mayo
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  - Clinic
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  - and paste it into somebody else's health care
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  - enterprise with outpatient clinic or a hospital or
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  - a public health system.
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  - It it just doesn't work because they have
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  - different regulatory environments. They have different places where
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  - they're starting
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  - compared to where we're practicing medicine.
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  - They have different drugs available to them. They
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  - have different staffing models. They have all sorts
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  - of different,
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  - extenuating
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  - circumstances
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  - that means health care needs to be very
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  - specific
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  - to their needs and where they are.
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  - So what we see is the journey we
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  - go on together
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  - is to work with our collaborators,
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  - identify where they are right now, and that's
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  - actually really important and not always easy, but
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  - that's the first body of work.
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  - Listen and understand
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  - where they want to go and then work
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  - together in a way that we are the
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  - knowledge partner and we can help
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  - advance and accelerate their health care and accelerate
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  - them on their journey to their vision.
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  - So for instance, I'll just give you a
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  - very tangible example. Let's say there's a group
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  - in another part of the world that wants
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  - to develop a cancer center.
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  - Well, there are many, many things that go
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  - into it. So we go and look at
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  - what are their capabilities, what are the,
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  - you know, infrastructure
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  - pieces they have in place,
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  - what are the staffing they have in place,
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  - where are the protocols, how are the patients
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  - referred, what are the payer models for those
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  - patients,
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  - and then use our experience and then help
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  - them move forward.
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  - That may involve some of their doctors perhaps
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  - coming to Mayo to train and learn a
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  - few things.
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  - It may involve us sending over many of
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  - our experts to train people in market. It
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  - may involve our facility
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  - experts, our supply chain experts, our nursing experts.
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  - The list is long because health care is
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  - complex.
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  - But we're there to help advance, accelerate,
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  - and
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  - elevate
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  - from our knowledge
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  - and move them to the place they wanna
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  - be. It's not exactly taking mayo and plopping
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  - it down someplace else.
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  - That makes a ton of sense. You know?
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  - And it was really much more thoughtful of
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  - an approach, in order to
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  - bring that level of care, but have that,
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  - as you mentioned, be all healthcare, being local,
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  - knowing how it fits into that culture, that
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  - community, and, what's going to make a big
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  - difference for you. So I know you've been
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  - deeply involved in the global HIV and infectious
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  - disease work from NIH funded research to committees,
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  - within the WHO and CDC. So how has
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  - that clinical and research background shaped the way
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  - you think about international healthcare and relationships?
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  - Oh, it's a great question. And in the
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  - global health world, I am a baby in
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  - the global health world. I'm engaged and involved,
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  - but compared to many of my colleagues who
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  - have devoted their entire career to global health,
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  - I have had the ability to experience it
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  - and be a part of it.
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  - And any knowledge, any experience in working with
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  - ministries of health, with other governments to understanding
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  - how research is performed in different government environments,
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  - how clinical trials are started
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  - either in The US or how you can
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  - do collaborative clinical trials
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  - across borders,
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  - how we can share data in some situations,
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  - how we can co enroll.
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  - All of that has been incredibly helpful for
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  - me
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  - to look at health care not just in
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  - a very narrow lens,
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  - but look at health care
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  - as an ecosystem.
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  - So clinical practice is obviously sort of the
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  - flashy hot part that everyone wants to talk
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  - about is how do we help our patients
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  - because that's what's most important.
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  - But I can tell you from my experience
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  - in working in education, working in research, working
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  - in global health, working with government agencies,
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  - working with international agencies,
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  - we have to think of that in a
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  - multifaceted
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  - way. We have to think about how we
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  - train the workforce for the next generation to
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  - keep taking care of this hospital. We'll plop
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  - down a hospital
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  - but not have a way to put in
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  - educational programs or workforce feeding programs
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  - would be very short sighted. And that has
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  - been very helpful, the experience I had previously.
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  - How do we continue
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  - to push health care to the edge for
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  - the patients who need new treatments that don't
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  - exist now?
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  - Or treatments that don't exist in their country
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  - or in their market.
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  - How do we get them involved in clinical
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  - trials?
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  - How do we get
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  - data information that the WHO is giving protocols,
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  - the CDC is giving protocols? How do we
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  - monitor that? How do we look at bio
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  - banking, collecting data in a way that'll inform
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  - what's happening in health care in that region?
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  - But also,
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  - it's a global world, like I keep saying
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  - in the pivotal words collaboration.
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  - How do we all share that work?
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  - Share that information. How do we share that
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  - work and continue to push science forward?
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  - At Mayo Clinic, we've got great data in
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  - The United States.
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  - But
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  - back when I used to do some of
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  - my HIV collaborations to work with groups in
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  - Africa,
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  - in India, in Southeast Asia. That's how we
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  - really start to understand disease on a better
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  - level and we all benefit from it. So
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  - it may have seemed like somewhat of a
• 10:56
  - windy path, but in retrospect, all those experiences
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  - I had before have been incredibly helpful to
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  - understand
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  - how you help
• 11:04
  - groups and how we at Mayo understand
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  - how to make
• 11:08
  - the future of health care sustainable.
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  - I love I love that. And, you know,
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  - I think especially when you look at health
• 11:16
  - care sustainability, there's so much that goes into
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  - it, whether you're looking at access points or
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  - the financial challenges,
• 11:23
  - from care providers as well as the patients
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  - in the communities. And so having that reliance
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  - on science and the clinical trials, the evidence,
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  - and to your point, ideally being able to,
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  - figure out how to
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  - provide better data in those spaces. And it
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  - really seems like it would make a difference.
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  - Absolutely. And, you know, it's easy to say
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  - share data. It's really hard to process three
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  - lines. So I don't want to,
• 11:50
  - minimize the work that goes into it, but
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  - I think it's
• 11:53
  - understanding the value and doing the work to
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  - as best as we can start to share
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  - that data. And if you can't even transfer
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  - data, start to share the understandings.
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  - Knowledge
• 12:04
  - should have no boundaries.
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  - Just because we discover a therapy or a
• 12:08
  - great protocol
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  - or a staffing model or anything you can
• 12:12
  - imagine, a therapeutic
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  - in The United States, it should benefit patients
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  - in Sri Lanka,
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  - in Kazakhstan,
• 12:21
  - in Australia, everywhere in the world. We should
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  - all benefit from each other's
• 12:25
  - knowledge and each other's advances.
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  - I love that. And what a great vision
• 12:30
  - and mission when you think about what health
• 12:32
  - care,
• 12:33
  - could potentially do and how it could really
• 12:35
  - be transformed globally.
• 12:37
  - Now I wanted to get into technology a
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  - bit more as well. How are some of
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  - the new technologies changing the field of infectious
• 12:43
  - disease from your perspective?
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  - Technology is changing everything,
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  - including medicine and very much so in infectious
• 12:51
  - disease. So there's so so many ways.
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  - I can kinda start at a 30,000 foot
• 12:56
  - level, then I'll take it down to sort
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  - of more
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  - granular levels.
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  - So anything to do with
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  - algorithms, large language models, machine learning, or what
• 13:08
  - we all colloquially
• 13:09
  - call artificial intelligence
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  - is absolutely
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  - transforming
• 13:14
  - infectious disease and population health.
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  - So we have the ability now to actually
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  - predict
• 13:21
  - outbreaks better than we ever had before. Before
• 13:24
  - we'd sit and wait till it hit us
• 13:25
  - in the face and then we'd be you
• 13:27
  - don't have to be reactionary.
• 13:29
  - Now we have the way with the data
• 13:31
  - in many different areas and working together to
• 13:34
  - actually predict when something's gonna happen. And again,
• 13:37
  - I'll give you a very, very specific example.
• 13:40
  - In the COVID pandemic,
• 13:42
  - as we were all across The United States
• 13:45
  - first starting to get COVID
• 13:47
  - and had a shortage of many personal protective
• 13:50
  - measures like masks and gloves and gowns,
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  - we were able to put together, we with
• 13:55
  - our collaborators at Mayo,
• 13:57
  - algorithms where we could do predictions
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  - on which little town was gonna get hit
• 14:02
  - next. So we can get the masks and
• 14:05
  - the gloves to them because we didn't have
• 14:07
  - enough for everybody just yet. We eventually would.
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  - But we can move it, all the equipment
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  - we needed and the,
• 14:14
  - the resources we needed ahead of time,
• 14:18
  - get there a day or two before the,
• 14:20
  - you know, peaks hit to make sure we're
• 14:23
  - using our resources most effectively.
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  - On top of all the algorithms that can
• 14:28
  - look at predicting antimicrobial
• 14:30
  - resistance and outbreaks and monitoring other parts of
• 14:33
  - diseases, infectious diseases that will happen,
• 14:37
  - we also, at a level lower, have much
• 14:39
  - better technology
• 14:41
  - for sequencing genomes, which matters if you're a
• 14:44
  - human to sequence our genome, but to sequence
• 14:46
  - all the pathogen genomes.
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  - So by doing that, we can actually diagnose
• 14:51
  - much faster,
• 14:52
  - far more specifically,
• 14:54
  - and very quickly predict resistance in many different
• 14:57
  - ways so we can treat quickly with the
• 15:00
  - right drug. And with multiomics, we can even
• 15:03
  - start to accelerate and understand
• 15:06
  - how the pathogen
• 15:07
  - may actually interact with other drugs so it's
• 15:10
  - actually helping feed drug development to get new
• 15:13
  - medicines as they're coming.
• 15:15
  - On top of that, we have machines. If
• 15:17
  - you talk about automation and robots,
• 15:20
  - In the past, if somebody was in a
• 15:21
  - hospital room and then left, we had to
• 15:23
  - have a human go in and decontaminate it.
• 15:26
  - And that can be quite a process particularly
• 15:28
  - for certain infectious diseases where you don't want
• 15:30
  - the next person to come in until it's
• 15:33
  - been fully sterilized.
• 15:34
  - We now have robots and automation that could
• 15:37
  - go in and sterilize a place.
• 15:39
  - We have ways in, much lower cost in
• 15:43
  - the field diagnostics.
• 15:45
  - So rather than somebody having to draw blood
• 15:47
  - and send it out, at Mayo Clinic, I
• 15:49
  - get the result quickly. But if you're, you
• 15:51
  - know, in another part of the world that
• 15:53
  - doesn't have
• 15:54
  - a massive
• 15:55
  - diagnostic lab in your backyard,
• 15:58
  - you used to have to send it out
• 15:59
  - and wait a very long time for the
• 16:01
  - results to come back, which impacts the antibiotics
• 16:04
  - being used, the care being given,
• 16:06
  - and the potential for others being infected.
• 16:09
  - Now we have low cost in the field
• 16:11
  - diagnostics
• 16:13
  - because of technology and because of these advances,
• 16:16
  - we can get diagnoses very very quickly.
• 16:18
  - So I could keep going on and on
• 16:20
  - and on. There are so many ways that
• 16:22
  - technology is impacting infectious disease
• 16:25
  - which is wonderful. It's exciting.
• 16:28
  - Is it all perfect? No. But that's part
• 16:29
  - of progressing.
• 16:31
  - It'll keep getting better
• 16:32
  - and, you know, you we will have far
• 16:35
  - more tools in our toolbox
• 16:37
  - to do what you need to do infectious
• 16:39
  - disease. Is to identify when the infection's coming,
• 16:42
  - hopefully ahead of time.
• 16:44
  - Be prepared for it.
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  - Diagnose
• 16:48
  - it very very quickly, and get the right
• 16:50
  - drug immediately at the right time to not
• 16:52
  - only take care of the patient, but infectious
• 16:55
  - disease compared to every other
• 16:58
  - specialty on the planet, we're not just dealing
• 17:00
  - with the human, we're dealing with the pathogen
• 17:01
  - too. And there's always a risk of infecting
• 17:04
  - others. So for us, it's not just treating
• 17:06
  - the patients so they get healthy, but preventing
• 17:08
  - others from getting infected as well.
• 17:11
  - Sorry. I could go I get very excited
• 17:13
  - when I start talking about stuff. No. That's
• 17:15
  - great. I can tell
• 17:16
  - You're very passionate, which is awesome. And I
• 17:18
  - think that's, you know, the most fun to
• 17:20
  - have people who are passionate about what they
• 17:22
  - do and and love, kind of changing the
• 17:24
  - field and and transformation in that way. So,
• 17:27
  - that's great.
• 17:29
  - Absolutely.
• 17:31
  - Excellent. Well, I think as we're, you know,
• 17:33
  - looking ahead,
• 17:35
  - Mayo Clinic has some recent engagement in markets
• 17:38
  - like Vietnam and the Gulf Region. So what
• 17:40
  - do you see as being the biggest opportunity
• 17:42
  - for global health collaborations over the next few
• 17:44
  - years?
• 17:46
  - Well, global health is more of what I
• 17:48
  - would consider sort of a public health initiative.
• 17:50
  - So there are many, many things we can
• 17:52
  - do in public health around the world,
• 17:54
  - but that's not specifically where Mayo is doing
• 17:56
  - most of its work in global health.
• 17:59
  - But through our collaborations, the Mayo Clinic International
• 18:03
  - in Southeast Asia,
• 18:05
  - in the GCC region,
• 18:07
  - in South America,
• 18:10
  - Mexico,
• 18:11
  - Central America,
• 18:12
  - China. There are many, many parts of the
• 18:14
  - world that we have.
• 18:16
  - Our partners, our collaborators, and people we're working
• 18:19
  - with. We really feel that that's how we
• 18:21
  - can together make a difference.
• 18:24
  - So as we share our knowledge and experience
• 18:27
  - in not just one, but in multiple markets
• 18:29
  - around the world,
• 18:31
  - we're touching, as you can imagine, so many
• 18:34
  - different lives.
• 18:35
  - And through some other initiatives that Mayo works
• 18:37
  - on, we are learning from those groups through
• 18:40
  - our data, through all sorts of different mechanisms
• 18:44
  - that now we can share. So it's not
• 18:47
  - just that
• 18:48
  - a Chinese group would have Chinese data, US
• 18:50
  - group would have US data,
• 18:52
  - and a Middle Eastern group would have their
• 18:54
  - data.
• 18:55
  - Suddenly, if we're all able to understand
• 18:58
  - each other's data and test algorithms,
• 19:01
  - test therapeutics,
• 19:02
  - test clinical trials against diverse genetic
• 19:06
  - and environmental
• 19:09
  - settings.
• 19:09
  - It's only gonna move our therapeutic development faster,
• 19:13
  - our diagnostics
• 19:14
  - faster, and our understanding of how to screen
• 19:17
  - and prevent disease faster.
• 19:20
  - We also find even in the work that
• 19:22
  - we do, which is a little more operational,
• 19:24
  - we are learning so much from these groups
• 19:27
  - as we're able to share our experience.
• 19:30
  - And then what we may learn from one
• 19:31
  - market not only influences what we know, but
• 19:34
  - then we can share it with other markets
• 19:36
  - as well.
• 19:37
  - So I think what you're hearing is the
• 19:40
  - mentality of a network.
• 19:42
  - It's not just few little one offs like
• 19:44
  - we're just gonna work in Mexico or we're
• 19:46
  - just gonna work in one area.
• 19:49
  - By us intentionally diversifying and touching many parts
• 19:53
  - of the world, we're really able to not
• 19:55
  - only serve our patients, their patients,
• 19:59
  - but also many other parts of the world
• 20:01
  - at the same time
• 20:02
  - by learning, sharing, and advancing
• 20:05
  - our ability to care for patients, our ability
• 20:07
  - to understand disease, our ability to push health
• 20:10
  - care forward together.
• 20:13
  - That's amazing to hear and, you know, truly,
• 20:15
  - truly a testament to the great power of
• 20:18
  - innovation that,
• 20:19
  - Mayo Clinic brings to, it seems like, everything
• 20:21
  - that you do and so much forward thinking
• 20:23
  - and,
• 20:24
  - really amazing that you're able to have such
• 20:26
  - an international reach. So thank you so much
• 20:29
  - for joining us on the podcast today, Doctor.
• 20:30
  - Rizzo. This has been a really fun and
• 20:32
  - informative conversation,
• 20:34
  - and inspired by your passion of how you're
• 20:36
  - attacking all the different things that you're working
• 20:37
  - on and, truly making a difference across the
• 20:40
  - world.
• 20:41
  - Well, thank you so much, and thank you
• 20:42
  - for taking an interest and working in health
• 20:45
  - care across the world. It's something clearly that
• 20:48
  - at Mayo Clinic we deeply believe in, and
• 20:50
  - we appreciate you helping us bring these stories
• 20:52
  - to life.