Latest / Intellectual Medicine / The Tests Men With Prostate Cancer Should Question First | Dr. Stephen Petteruti
Transcript
- 0:00We all want to live long. We all want vitality.
- 0:02None of us want to age. But there's so much smoke and
- 0:07mirrors out there gang. There are a lot of would be anti
- 0:11aging specialist body hackers that are using the ambition you
- 0:17have for legitimate anti aging to direct you toward proprietary
- 0:23pathways selling you junk. Look, I don't mind selling you
- 0:27stuff, but it damn well better work, better be substance behind
- 0:31it. All right?
- 0:33Body hackers, we all. Want to live long?
- 0:36We all want vitality. None of us want to age.
- 0:40But there's so much smoke and mirrors out there, gang.
- 0:44My job, in part, is to separate the myth from the reality.
- 0:50So here are the things that I think are really kind of dorky
- 0:55and I don't think you should do. There are a lot of well would be
- 1:00anti aging specialist body hackers that are using the
- 1:06ambition you have for legitimate anti aging to direct you toward
- 1:12well proprietary pathways selling you junk.
- 1:17But I don't mind selling you stuff.
- 1:19But it damn well better work, better be substance behind it.
- 1:23So let's get right to it. Here's one thing I heartily
- 1:27recommend you never do a DEXA scan.
- 1:32These DEXA scans are promoted as a means of assessing percent
- 1:37body fat, muscle mass. They can do that, but at what
- 1:42price? You're being exposed to ionizing
- 1:46radiation, people. That's carcinogenic.
- 1:50You don't need it. You can get a good assessment of
- 1:54percent body fat and muscle mass through bio electric impedance
- 2:01testing. The in body is 1 brand name.
- 2:04There are others. Although I like that device, we
- 2:07use it in my practice. It enables us to determine
- 2:11percent body fat and muscle mass and compare it over time without
- 2:17risking your health, without exposing you to radiation.
- 2:21You don't fight aging by willfully exposing yourself to
- 2:26carcinogens. It is important to know how the
- 2:30muscles are doing. As go the muscle, so goes the
- 2:33bone. More muscle, more vitality,
- 2:37longer life, so bone density. No assessing muscle mass,
- 2:43Absolutely. What's a better way to do that?
- 2:46Simple grip strength. These are well validated metrics
- 2:52that correlate better with lifespan and health than blood
- 2:57pressure, than cholesterol levels, than DEXA scans.
- 3:03It's not sexy. It's a literal grip strength
- 3:07inexpensive device that any anti aging specialist should be
- 3:11familiar with and make available to you.
- 3:14It doesn't cost really anything. So this is part of my standard
- 3:18assessments is getting grip strength so we can serve as a
- 3:22point of comparison year over year.
- 3:26It's another thing that I that I don't like and I don't think you
- 3:29should ever do. I'm not a big advocate.
- 3:32In fact, I've never ordered a biological aging blood test.
- 3:39Really, these things are completely made-up, and they're
- 3:43projecting or attempting to correlate it with your
- 3:48biological age, a ridiculous concept.
- 3:52They can tell from a blood test where you rank.
- 3:55Yeah, they can compare biometric markers.
- 4:01They can compare them based upon age norms.
- 4:05That's not that relevant. What matters the most is not
- 4:09your biological biometric age. There are lab tests worthy of
- 4:15evaluating and worthy of tracking, but they don't predict
- 4:19your age, folks. So let's just stop this fantasy.
- 4:22Oh, my biological age is actually 28.
- 4:26Really, what matters is your segmental age.
- 4:31Segmental age? We don't age the same.
- 4:34If your brain is going fast, that supersedes any biometric.
- 4:40How about your heart? Your arteries?
- 4:43How about your joints? If your biological age based on
- 4:47some made-up metric is 28, but you've got advanced arthritis in
- 4:53your joints, you could have a joint that's 80 years old.
- 4:57That's the focus. We are as young as our oldest
- 5:02part, so looking at it segmentally far more important.
- 5:07How do you do that? History helps.
- 5:10There are some imaging studies that can help.
- 5:13I don't like doing a whole body MRI.
- 5:16That's another thing that is a ridiculous waste of money.
- 5:20You're going to look for what, for cancer, for hardening of the
- 5:25arteries, and you're going to find shadows all over the place.
- 5:29It's going to create anxiety. It's going to create false
- 5:33targets. Now you find a cyst in your
- 5:36liver. Most people have them.
- 5:38Oh, but it could be something. You're going to find a nodule in
- 5:43your kidney. You're going to find a lump in
- 5:45your thyroid. Far better to do targeted
- 5:51segmental assessment. At the right age, say 50 or
- 5:56older, a calcium score of your heart is worth getting.
- 5:59It's a CAT scan of your heart. It can tell you whether or not
- 6:03and how much hardening of the arteries you have calcium build
- 6:07up. It's inexpensive.
- 6:09Yes it's radiation exposure, but it's a one and done test.
- 6:13You don't track this test that frequently.
- 6:16It doesn't change that quickly. At age 50 if your calcium scores
- 6:21is 0. Good news, your risk of a heart
- 6:24attack, stroke, heart failure, practically non existent for the
- 6:28next 10 years. A valuable tool to help
- 6:31determine how aggressively you should be focusing on
- 6:35cardiovascular, either support or restoration.
- 6:40Another test worth getting is a consideration.
- 6:45It's actually an MRI of your brain.
- 6:47I mean, why not? Your brain is a vital part of
- 6:50your aging dynamic that most people kind of ignore.
- 6:55You can be losing cognitive function without knowing it.
- 7:00Your brain adapts, it fills in the blanks, the words you can't
- 7:04find. It builds a bridge over them.
- 7:06Executive function can corrode, but you can compensate for that
- 7:12until you can't. A brain MRI is a reasonable
- 7:15consideration without contrast, right?
- 7:18No radiation. It can help determine.
- 7:21Do you have microvascular changes?
- 7:26Are the capillaries damaged in a manner that is slowly killing
- 7:30off neurons? So I like a one shot brain MRI.
- 7:36What else do I like? Well, I like the told you
- 7:40calcium score, the brain MRI. There's a test you can do to
- 7:46help assess future cardiovascular risk in addition
- 7:49to the ones I described. It's called the prevent
- 7:52calculator. That's prevent PREVENT
- 7:57calculator. You can put that in a search
- 8:00engine and the calculator will pop up.
- 8:03With the help of your doctor, you can order the necessary
- 8:06testing, plug in the numbers and it will give you a 10 year risk
- 8:11of heart attack, stroke, heart failure.
- 8:16It's fantastic because it's the most accurate metric yet
- 8:20devised. It supersedes.
- 8:21It's better than what's out there currently, although it's
- 8:24not fully mainstreamed yet. They look at things like total
- 8:28cholesterol, HDL, your hemoglobin A1C measure of blood
- 8:34sugar. Look at your creatinine
- 8:37clearance, how well is your kidney filtering.
- 8:40Look at the albumin to creatinine ratio in your urine.
- 8:46This test can be easily ordered. Ask your doctor for it.
- 8:50It'll tell you whether or not you're spilling protein into the
- 8:54urine. An early sign of kidney damage,
- 8:57which connects to arterial health.
- 9:00All these things linked together, things not to get.
- 9:06There's something out there called Lifeline where they
- 9:09assess your arteries, they do an ultrasound of your abdomen, your
- 9:13feet for peripheral vascular disease.
- 9:15It sounds good, but it is useless.
- 9:20You can make the same assessments just through your
- 9:23history and if needed, imaging studies can be ordered in a
- 9:29targeted manner. Brain, heart, kidney, these are
- 9:36the areas we want to look at. Musculoskeletal that is
- 9:40primarily history based. You don't need X-rays of your
- 9:44joints. You really don't.
- 9:46I really don't like getting X-rays just to see what's there.
- 9:51If it'll make a decision about treatment that's different.
- 9:55Once you know what you know, you don't have to track it.
- 9:58What do I mean? So I have an arthritic shoulder
- 10:02well established, had an X-ray three years ago.
- 10:05It was bone on bone, saith the doctor.
- 10:08Of course you guys know I don't believe in that Bone on bone
- 10:11doesn't really reflect what's going on in the joint.
- 10:15After all of his bone on bone, you can't move it because, well,
- 10:19it's bone upon bone. If I can move my shoulder, let
- 10:23me show it off my range of motion.
- 10:26If I can move my shoulder, it tells me that the surface is
- 10:31still intact on a microscopic level.
- 10:35The idea of regrowing cartilage, Your body attempts to do that.
- 10:41It can happen. Orthopaedic docs don't believe
- 10:44in that. But history defies the common
- 10:49notion that bone on bone is irreversible.
- 10:52So I guess I'll put that in my category of things to be
- 10:55cautious about. Be wary of getting joints
- 10:58replaced if it has to happen. I get it, it's something that
- 11:03may enhance function when pain can't otherwise be controlled.
- 11:08But go slowly down that path, try to regenerate your joints,
- 11:12and if it gets replaced, remember the muscles that
- 11:17surround it or what's going to maintain it for as long as
- 11:21possible. Once that joint gets replaced,
- 11:23it's going to start to decay, so you want to avoid weakening the
- 11:29muscles that surround it. And this is where things like
- 11:32testosterone and the proper use of peptides can come in.
- 11:36And while I'm on that topic, I'll put that in my category of
- 11:40things not to do. Body hackers that are going
- 11:44online and buying peptides for research purposes only.
- 11:49That's how they're labeled. That means they were
- 11:52manufactured likely overseas. They're manufactured in a manner
- 11:57that is not fit for human use. One study found that the
- 12:03majority of peptides tested for human for experimental purposes
- 12:08only. These are the kind you can buy
- 12:11direct online. You'll get bombarded by them
- 12:15with all the promotional hype that goes along with it.
- 12:19How fantastic they are. I'm going to do peptide
- 12:22stacking. No, you're going to be exposing
- 12:26yourself to fruitless expense in most cases with unknown purity
- 12:32and quality. One study found that the
- 12:35majority of peptides sold online had in fact nothing in them.
- 12:43They were selling you powder. A placebo.
- 12:49How about purity? If they say it's 99% pure,
- 12:53that's contaminated folks. It doesn't take much to create
- 12:58an adverse reaction. Furthermore, there's a better
- 13:02solution. Yes, there are peptides that are
- 13:05completely legal for doctors to prescribe.
- 13:09If you're using a peptide, it should be coming from a doctor
- 13:13or a nurse practitioner. In some cases, a licensed
- 13:17naturopath can have authority to prescribe.
- 13:20It should not be coming from Freddie the body hacker online.
- 13:25These people are there for a purpose and the purpose is to
- 13:28make them money and sell you stuff with a bunch of hype
- 13:32without much tangible value. Peptides, properly directed,
- 13:37properly utilized, can have a niche to fill, but they should
- 13:42be from a cleared American compounding pharmacy.
- 13:49And if they're not, they're not worth it.
- 13:50Folks, you could do better things with your time, with your
- 13:53money, with better effect. There are peptides that are
- 13:56clean and available. You want to have a legitimate
- 13:59provider. If a doctor or provider guides
- 14:02you towards black market peptides, in my opinion, they're
- 14:07operating below the highest ethical standards.
- 14:11You cannot do that to people in clear conscience thinking that
- 14:15they'll be no potential adverse effect.
- 14:18In fact, it might even be technically illegal, but I'm not
- 14:22here to be a whistleblower. I'm here to help you stay vital
- 14:26stay healthy yes maintain anti aging.
- 14:30So avoiding the hype, avoiding the false notions, avoiding the
- 14:37the pitch for targeted supplements based upon specious
- 14:43lab testing. So most of the places where you
- 14:47can get biological age testing done, they're going to link that
- 14:51to supplements you should use to make your biological age score
- 14:55look better. OK, it's just a circular logic.
- 15:02You're treating numbers and labs, not cellular health.
- 15:07Another thing that I don't believe has merit this over
- 15:12promotion of MTHFR mutation imposing or at least implying
- 15:21that you are methylating in an inefficient inappropriate manner
- 15:25and because you have a mutation called the MTHFR, you need
- 15:30special supplements so you can methylate better.
- 15:36Methylation is valuable, it's important, and there are some
- 15:38people that are methylate that are challenged in their ability
- 15:41to methylate a relative minority of them.
- 15:45It can be assessed quite easily by looking at your homocysteine
- 15:49level. It can be assessed quite easily,
- 15:51easily by looking at the folate and the vitamin B12 levels.
- 15:55There are legitimate ways to look at it, but methylation
- 15:59mutation is a mislabel. We all have MTHFR genotypes.
- 16:07It would be like calling blue eyes a mutation.
- 16:11It is a trait. So you, me, all of us, we have
- 16:17an MTHFR trait and there are very few people, an exquisite
- 16:24minority that have a true mutation that imposes risk to
- 16:31their health. One of the most sensitive
- 16:34markers for methylation inadequacy is an elevated
- 16:39homocysteine level simple blood test easily acquired.
- 16:43So avoid the hyper promotion of supplements.
- 16:51Link up with a provider that can help guide you in that in that
- 16:54space as well. If you're buying a supplements
- 16:57online from a company that sells supplements, it's hard to get a
- 17:01straight answer. I like clinicians who really you
- 17:07pay them for their mind, for their guidance, for their
- 17:09opinion, but they're relatively agnostic when it comes to the
- 17:15supplements that they'll recommend.
- 17:17Focusing really on what's best for the patient.
- 17:21That's the goal, that's the direction.
- 17:24So get me to a good anti aging specialist.
- 17:28They're out there. You know, I've been doing this
- 17:31for many years. You don't find it through
- 17:34conventional medicine. I will say another tip for your
- 17:37anti aging pursuit, a Doctor Who is working for a company, a
- 17:44hospital, a group, or is taking a conventional insurance as
- 17:51reimbursement is less likely to have the interest, the knowledge
- 17:56and the capacity to fully engage in your anti aging guided
- 18:02therapy. It's not that they are
- 18:04incapable, it's just they're put themselves in a position of
- 18:09having to follow the standard of care for conventional medicine.
- 18:15It's a separate universe. You got conventional medicine
- 18:18over here, disease intervention. You have what you and I really
- 18:23want, vitality, youthful energy, a lack of decay.
- 18:30That, my friends, requires guidance from a clinician who's
- 18:34dedicated significant time to acquiring the fund of knowledge
- 18:38to guide you and can give you the time needed to execute that
- 18:43path. Well, I hope these tips have
- 18:46helped you a little bit. I hope they, I hope they help
- 18:49you focus. Look, we all have a finite
- 18:52budget. Time, money, swallow capacity,
- 18:57injection tolerance. There are a lot of things out
- 19:01there. You can't do them all.
- 19:03You want to do the ones that matter the most to you.
- 19:06So avoid radiation, avoid DEXA scans, avoid well specious
- 19:13testing, biological aging, lot of smoke and mirrors.
- 19:20One last thing to avoid VO2 Max. I see this promoted a lot.
- 19:27It is a test of how efficiently your body is utilizing oxygen.
- 19:33It is true that if you have a good VO2 Max, you're well
- 19:36conditioned. A lot of athletes have a
- 19:39fabulous VO2 Max. It doesn't mean, however,
- 19:42they're going to live a long time.
- 19:44It just means that you're conditioned.
- 19:47The idea that this parallels longevity is a false
- 19:51extrapolation. It parallels conditioning.
- 19:56It parallels cardiovascular capacity.
- 19:59You look at NBA players have a great the O2 Max.
- 20:02Are they going to live long? A lot of pro athletes have
- 20:06disappointingly short life spans.
- 20:09So I don't like the O2 Max as a metric of anti aging.
- 20:14I think if you want to utilize it to measure your conditioning
- 20:17regimen, I suppose that's OK. You can get the same result by
- 20:22doing more simple testing. One last Test.
- 20:25One last Test that's worth considering.
- 20:28It's called the Sit stand test. I know it sounds stupidly simple
- 20:33because it is. You literally cross your hands
- 20:37over your shoulders like this and in 30 seconds see how many
- 20:41times you can stand, sit and stand again with a chair
- 20:45underneath your butt. Standard chair.
- 20:48Look at that number and then compare it year over year.
- 20:54It should remain stable or improve.
- 20:56That test correlates better with longevity than VO2 Max.
- 21:01Simple and expensive. All right, well, that's all I
- 21:04got for today team. Thanks for watching and let's
- 21:08keep fighting aging. Let's live the future like it's
- 21:12now. Staying vital.
- 21:14Get old chronologically, but not physiologically.
- 21:19See you next time.