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515-Human MGE Development and Inhibitory Neurogenesis

Research identifies subventricular zone radial glial cells (SVZ RGCs) as a novel progenitor population in the human medial ganglionic eminence. These cells drive the expanded production of GABAergic inhibitory neurons, contributing to the high cognitive capacity of the human brain.

References:

Jia L, Li X, Yan Y, et al. Subventricular zone radial glial cells maintain inhibitory neuron production in the human brain[J]. Science, 2026, 391(6782): eadw1803.

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