Prostate Cancer with PTEN Deficiency — An Interview with Dr Neeraj Agarwal (Companion Faculty Lecture)

Research To Practice | Oncology Videos · Oct 2, 2026 · 23m

Featuring a slide presentation and related discussion from Dr Neeraj Agarwal, including the following topics:

Therapeutic targets of systemic therapy in prostate cancer (0:00)

Prevalence of genomic alterations in prostate cancer including PTEN deficiency; prognostic and predictive value (3:52)

Optimal timing of and approach to PTEN assessment; pathophysiology surrounding PTEN loss (9:29)

Comparison of ipatasertib and capivasertib; key findings from Phase III IPATential150 and CAPItello-281 studies (14:26)

Safety and tolerability profile of capivasertib; strategies for management of adverse…