445-The Human Skin Microbiome: Metagenomes to Therapeutics
This review explores the human skin microbiome, detailing how a complex ecosystem of bacteria, fungi, and viruses maintains dermatological health and immune function. Advances in metagenomic sequencing have allowed researchers to identify specific microbial shifts associated with conditions like atopic dermatitis, acne, and psoriasis. By understanding these interspecies interactions, scientists are developing novel microbiome-based therapeutics, including probiotics, phage therapy, and engineered bacteria. While these treatments offer targeted precision for skin repair and inflammation, they…
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