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Dr. Anne O'Dea & Dr. Mabel Mardones - SERENA-6 & ctDNA-Guided Therapy in mBC

Can we improve outcomes by changing treatment before radiographic progression occurs?

In this in-depth discussion, Dr. Anne O'Dea and Dr. Mabel Mardones explore how the SERENA-6 trial is reshaping the management of HR-positive, HER2-negative metastatic breast cancer through ctDNA-guided treatment decisions and earlier intervention for emerging ESR1 mutations.

Topics discussed include:

The clinical impact of the SERENA-6 trial

Using ctDNA to detect ESR1 mutations before disease progression

When and why to switch endocrine therapy

Camizestrant and molecularly guided treatment strategies…

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