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The Medicine That Never Crossed the Threshold: DOET's Lost Promise
The Medicine That Never Crossed the Threshold: DOET's Lost Promise
Calm euphoria at one milligram, no hallucinations, no cardiovascular effects - a drug that behaved like medicine but was buried because its cousin became a scandal. How did a compound that passed three clinical trials and earned a place among a chemist’s “ten classics” vanish from medicine?
In this episode, we tell the story of DOET’s discovery, its clinical results, and the events that stopped its development - and ask how a safe, nonhallucinogenic compound ended up abandoned after a chemical relative sparked a public health…
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