Paroxysmal Nocturnal Hemoglobinuria | Practical Perspectives: Investigators Discuss the Current Management of Paroxysmal Nocturnal Hemoglobinuria

Featuring perspectives from Dr Gloria Gerber, Dr Jamie Koprivnikar, Prof Alexander Röth and Dr Jamile M Shammo, including the following topics:

Introduction: Paroxysmal Nocturnal Hemoglobinuria (PNH) and the General Medical Oncologist

Diagnosis of and myths and misperceptions about PNH (0:00)

Overview — Biology and Pathophysiology

Role of complement activation in PNH; classification and clinical presentation (7:00)

PNH treatments and their complement targets (21:37)

Current Management Approaches

Mechanistic similarities and differences between crovalimab and other available C5 inhibitors…

The skinny

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