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When Protein Stops Working, and How to Make Midlife Muscle Respond

Ever feel like you’re “doing everything right”—eating plenty of protein—yet your strength and muscle just aren’t responding the way they used to? You’re not imagining it. In this episode, Dr. Laurie Marbas breaks down anabolic resistance: the very real midlife shift where the same protein-rich meal that once sparked muscle-building barely moves the needle.

You’ll hear about the surprising “two-week trap” research—how cutting daily movement (without changing diet) can reduce lean tissue, strength, and your muscle’s response to protein in as little as 10–14 days. Then we simplify the science…

The skinny

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